Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1.

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Published in Bioorg Med Chem Lett on February 12, 2010

Authors

John G Catalano1, Kristjan S Gudmundsson, Angilique Svolto, Sharon D Boggs, John F Miller, Andrew Spaltenstein, Michael Thomson, Pat Wheelan, Doug J Minick, Dean P Phelps, Stephen Jenkinson

Author Affiliations

1: Department of Medicinal Chemistry, Infectious Diseases Center of Excellence for Drug Discovery, GlaxoSmithKline Research & Development, Five Moore Drive, Research Triangle Park, NC 27709-3398, USA. john.g.catalano@gsk.com

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