Published in Infect Immun on May 01, 1991
Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis. J Exp Med (1998) 3.68
Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein. J Exp Med (2001) 2.76
Genetics of mosquito vector competence. Microbiol Mol Biol Rev (2000) 2.19
Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: An adaptive response induced by the fly? Proc Natl Acad Sci U S A (2000) 1.58
Implication of haematophagous arthropod salivary proteins in host-vector interactions. Parasit Vectors (2011) 1.39
Saliva of the Lyme disease vector, Ixodes dammini, blocks cell activation by a nonprostaglandin E2-dependent mechanism. J Exp Med (1994) 1.39
Sand fly saliva enhances Leishmania amazonensis infection by modulating interleukin-10 production. Infect Immun (2004) 1.35
Effects of sand fly vector saliva on development of cutaneous lesions and the immune response to Leishmania braziliensis in BALB/c mice. Infect Immun (1996) 1.32
Characterization of the antibody response to the saliva of Phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis. Am J Trop Med Hyg (2011) 1.14
Phlebotomus papatasi saliva inhibits protein phosphatase activity and nitric oxide production by murine macrophages. Infect Immun (1998) 1.07
Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis. PLoS Negl Trop Dis (2010) 1.02
Human cellular immune response to the saliva of Phlebotomus papatasi is mediated by IL-10-producing CD8+ T cells and Th1-polarized CD4+ lymphocytes. PLoS Negl Trop Dis (2011) 0.92
Sand-fly saliva-leishmania-man: the trigger trio. Front Immunol (2013) 0.92
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. Am J Trop Med Hyg (2010) 0.91
Maxadilan, a PAC1 receptor agonist from sand flies. Peptides (2007) 0.91
What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity. Infect Genet Evol (2014) 0.91
Immunity to visceral leishmaniasis using genetically defined live-attenuated parasites. J Trop Med (2011) 0.91
Experimental infection of dogs with Leishmania and saliva as a model to study Canine Visceral Leishmaniasis. PLoS One (2013) 0.90
DNA vaccination with KMP11 and Lutzomyia longipalpis salivary protein protects hamsters against visceral leishmaniasis. Acta Trop (2011) 0.89
Analysis of salivary gland transcripts of the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis. Infect Genet Evol (2012) 0.88
Cooperative blood-feeding and the function and implications of feeding aggregations in the sand fly, Lutzomyia longipalpis (Diptera: Psychodidae). PLoS Negl Trop Dis (2009) 0.83
The protein LJM 111 from Lutzomyia longipalpis salivary gland extract (SGE) accounts for the SGE-inhibitory effects upon inflammatory parameters in experimental arthritis model. Int Immunopharmacol (2012) 0.81
Validation of Recombinant Salivary Protein PpSP32 as a Suitable Marker of Human Exposure to Phlebotomus papatasi, the Vector of Leishmania major in Tunisia. PLoS Negl Trop Dis (2015) 0.80
Meta-analysis of the effects of insect vector saliva on host immune responses and infection of vector-transmitted pathogens: a focus on leishmaniasis. PLoS Negl Trop Dis (2014) 0.80
Hitchhiking of host biology by beneficial symbionts enhances transmission. Sci Rep (2014) 0.79
Experimental models in vaccine research: malaria and leishmaniasis. Braz J Med Biol Res (2013) 0.79
Salivary gland homogenates from wild-caught sand flies Lutzomyia flaviscutellata and Lutzomyia (Psychodopygus) complexus showed inhibitory effects on Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis infection in BALB/c mice. Int J Exp Pathol (2014) 0.78
Leishmania enriettii: biochemical characterisation of lipophosphoglycans (LPGs) and glycoinositolphospholipids (GIPLs) and infectivity to Cavia porcellus. Parasit Vectors (2015) 0.78
Study of Leishmania pathogenesis in mice: experimental considerations. Parasit Vectors (2016) 0.77
Immunogenicity and Serological Cross-Reactivity of Saliva Proteins among Different Tsetse Species. PLoS Negl Trop Dis (2015) 0.76
Characterization of an I-E-restricted, gp63-specific, CD4-T-cell clone from Leishmania major-resistant C3H mice that secretes type 2 cytokines and exacerbates infection with L. major. Infect Immun (2004) 0.75
Insights into the sand fly saliva: Blood-feeding and immune interactions between sand flies, hosts, and Leishmania. PLoS Negl Trop Dis (2017) 0.75
Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity. Science (1988) 4.10
Identification of an infective stage of Leishmania promastigotes. Science (1984) 4.00
Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J Immunol (1985) 3.47
Role of saliva in blood-feeding by arthropods. Annu Rev Entomol (1987) 2.78
Immunological regulation of experimental cutaneous leishmaniasis. 1. Immunogenetic aspects of susceptibility to Leishmania tropica in mice. Parasite Immunol (1980) 2.54
The effect of post-bloodmeal nutrition of Phlebotomus papatasi on the transmission of Leishmania major. Am J Trop Med Hyg (1986) 1.78
Immunological regulation and control of experimental leishmaniasis. Int Rev Exp Pathol (1986) 1.75
A mouse model of Leishmania braziliensis braziliensis infection produced by coinjection with sand fly saliva. J Exp Med (1991) 1.70
The role of vector saliva in transmission of arthropod-borne disease. Parasitol Today (1990) 1.48
Peptides encoded by the calcitonin gene inhibit macrophage function. J Immunol (1989) 1.19
A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. Science (1989) 1.16
A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol (1985) 4.71
Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity. Science (1988) 4.10
Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J Immunol (1985) 3.47
Antibody testing in Lyme disease. A comparison of results in four laboratories. JAMA (1990) 3.20
Methodological concerns and recommendations on policy consequences of the World Health Report 2000. Lancet (2001) 3.04
Dissemination and salivary delivery of Lyme disease spirochetes in vector ticks (Acari: Ixodidae). J Med Entomol (1987) 3.00
Role of saliva in blood-feeding by arthropods. Annu Rev Entomol (1987) 2.78
Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein. J Exp Med (2001) 2.76
Comparing the relative potential of rodents as reservoirs of the Lyme disease spirochete (Borrelia burgdorferi). Am J Epidemiol (1989) 2.62
Apoptosis and disease. Lancet (1993) 2.55
Exacerbation of murine cutaneous leishmaniasis by adoptive transfer of parasite-specific helper T cell populations capable of mediating Leishmania major-specific delayed-type hypersensitivity. J Immunol (1984) 2.35
Human immune response to sand fly salivary gland antigens: a useful epidemiological marker? Am J Trop Med Hyg (2000) 2.18
Antihemostatic, antiinflammatory, and immunosuppressive properties of the saliva of a tick, Ixodes dammini. J Exp Med (1985) 1.97
Increased intradermal probing time in sporozoite-infected mosquitoes. Am J Trop Med Hyg (1984) 1.93
Regulation of differentiation to the infective stage of the protozoan parasite Leishmania major by tetrahydrobiopterin. Science (2001) 1.77
Sandfly maxadilan exacerbates infection with Leishmania major and vaccinating against it protects against L. major infection. J Immunol (2001) 1.74
Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis. J Biol Chem (2000) 1.73
A simple method for quantifying Leishmania in tissues of infected animals. Parasitol Today (1997) 1.61
An OspC-specific monoclonal antibody passively protects mice from tick-transmitted infection by Borrelia burgdorferi B31. Infect Immun (1999) 1.60
Exploring the transcriptome of the malaria sporozoite stage. Proc Natl Acad Sci U S A (2001) 1.59
Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: An adaptive response induced by the fly? Proc Natl Acad Sci U S A (2000) 1.58
Toward an understanding of the biochemical and pharmacological complexity of the saliva of a hematophagous sand fly Lutzomyia longipalpis. Proc Natl Acad Sci U S A (1999) 1.57
The salivary gland-specific apyrase of the mosquito Aedes aegypti is a member of the 5'-nucleotidase family. Proc Natl Acad Sci U S A (1995) 1.56
Patterns of cytokine secretion in murine leishmaniasis: correlation with disease progression or resolution. Infect Immun (1990) 1.55
Intracellular destruction of Leishmania tropica by macrophages activated with macrophage activating factor/interferon. Clin Exp Immunol (1984) 1.51
The role of vector saliva in transmission of arthropod-borne disease. Parasitol Today (1990) 1.48
Orally induced tolerance. Definition at the cellular level. Int Arch Allergy Appl Immunol (1981) 1.48
Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice. J Immunol (1986) 1.45
Experimental syphilis in the rabbit: passive transfer of immunity with immunoglobulin G from immune serum. J Infect Dis (1979) 1.44
The immunomodulatory factors of bloodfeeding arthropod saliva. Parasite Immunol (2000) 1.42
The salivary apyrase of the blood-sucking sand fly Phlebotomus papatasi belongs to the novel Cimex family of apyrases. J Exp Biol (2001) 1.40
Saliva of the Lyme disease vector, Ixodes dammini, blocks cell activation by a nonprostaglandin E2-dependent mechanism. J Exp Med (1994) 1.39
Chitinases of the avian malaria parasite Plasmodium gallinaceum, a class of enzymes necessary for parasite invasion of the mosquito midgut. J Biol Chem (2000) 1.39
Effects of sand fly vector saliva on development of cutaneous lesions and the immune response to Leishmania braziliensis in BALB/c mice. Infect Immun (1996) 1.32
Isolation of maxadilan, a potent vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. J Biol Chem (1991) 1.32
Saliva of Lutzomyia longipalpis sibling species differs in its composition and capacity to enhance leishmaniasis. Philos Trans R Soc Lond B Biol Sci (1994) 1.29
Sand fly vector saliva selectively modulates macrophage functions that inhibit killing of Leishmania major and nitric oxide production. J Immunol (1995) 1.28
Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme. J Biol Chem (1998) 1.28
Salivary apyrase of Aedes aegypti: characterization and secretory fate. Comp Biochem Physiol B (1984) 1.27
Role of mosquito saliva in blood vessel location. J Exp Biol (1984) 1.24
Anti-tick antibodies: an epidemiologic tool in Lyme disease research. Am J Epidemiol (1990) 1.23
Purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus. J Biol Chem (2000) 1.22
Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis. J Immunol (2001) 1.21
Peptides encoded by the calcitonin gene inhibit macrophage function. J Immunol (1989) 1.19
Variation in the salivary peptide, maxadilan, from species in the Lutzomyia longipalpis complex. Insect Mol Biol (1999) 1.19
Salivary gland material from the sand fly Lutzomyia longipalpis has an inhibitory effect on macrophage function in vitro. Parasite Immunol (1993) 1.19
Phlebotomus papatasi sand fly salivary gland lysate down-regulates a Th1, but up-regulates a Th2, response in mice infected with Leishmania major. J Immunol (1998) 1.18
Isoelectric points of proteins: theoretical determination. Anal Biochem (1989) 1.18
Anophelin: kinetics and mechanism of thrombin inhibition. Biochemistry (1999) 1.17
Purification, partial characterization, and cloning of nitric oxide-carrying heme proteins (nitrophorins) from salivary glands of the blood-sucking insect Rhodnius prolixus. J Biol Chem (1995) 1.17
Nitric oxide binding and crystallization of recombinant nitrophorin I, a nitric oxide transport protein from the blood-sucking bug Rhodnius prolixus. Biochemistry (1997) 1.14
Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response. J Infect Dis (1996) 1.14
Variants with reduced virulence derived from Leishmania major after mutagen treatment. Parasite Immunol (1987) 1.12
A salivary nitrophorin (nitric-oxide-carrying hemoprotein) in the bedbug Cimex lectularius. J Exp Biol (1995) 1.12
Analysis of the immune responses of mice to infection with Leishmania braziliensis. Infect Immun (1998) 1.11
A simple and effective method to assess murine delayed type hypersensitivity to proteins. J Immunol Methods (1981) 1.11
Leishmania major-parasitized macrophages augment Th2-type T cell activation. J Immunol (1994) 1.11
Borrelia burgdorferi-pulsed dendritic cells induce a protective immune response against tick-transmitted spirochetes. Infect Immun (1997) 1.11
Increased biting rate and reduced fertility in sporozoite-infected mosquitoes. Am J Trop Med Hyg (1986) 1.11
Nitric oxide loading of the salivary nitric-oxide-carrying hemoproteins (nitrophorins) in the blood-sucking bug Rhodnius prolixus. J Exp Biol (1995) 1.10
Role of tumor necrosis factor in macrophage leishmanicidal activity in vitro and resistance to cutaneous leishmaniasis in vivo. Infect Immun (1991) 1.10
Aedes aegypti: model for blood finding strategy and prediction of parasite manipulation. Exp Parasitol (1985) 1.07
Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti. Proc Natl Acad Sci U S A (1994) 1.07
Purification, cloning, and synthesis of a novel salivary anti-thrombin from the mosquito Anopheles albimanus. Biochemistry (1999) 1.06
Considerations on methodology used in the World Health Organization 2000 Report. Cad Saude Publica (2001) 1.05
Biochemical insights derived from insect diversity. Annu Rev Biochem (1992) 1.05
Nitrophorin-2: a novel mixed-type reversible specific inhibitor of the intrinsic factor-X activating complex. Biochemistry (1998) 1.03
Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. Proc Natl Acad Sci U S A (1992) 1.03
Can satyrs control pests and vectors? J Med Entomol (1988) 1.02
Purification and cloning of the salivary nitrophorin from the hemipteran Cimex lectularius. J Exp Biol (1998) 1.02
Blood-finding strategy of a capillary-feeding sandfly, Lutzomyia longipalpis. Comp Biochem Physiol A Comp Physiol (1986) 1.01
Histologic characterization of experimental cutaneous leishmaniasis in mice infected with Leishmania braziliensis in the presence or absence of sand fly vector salivary gland lysate. J Parasitol (1998) 1.01
T cell and non-T cell compartments can independently determine resistance to Leishmania major. J Exp Med (1995) 1.00
Lyme disease and babesiosis: acaricide focused on potentially infected ticks. Am J Trop Med Hyg (1987) 0.99
Platelet antiaggregating activity in the salivary secretion of the blood sucking bug Rhodnius prolixus. Experientia (1981) 0.98
Leishmania major-specific, CD4+, major histocompatibility complex class II-restricted T cells derived in vitro from lymphoid tissues of naive mice. J Exp Med (1993) 0.98
5-hydroxytryptamine in the salivary glands of adult female Aedes aegypti and its role in regulation of salivation. J Exp Biol (1995) 0.97
A snake venom phospholipase A(2) blocks malaria parasite development in the mosquito midgut by inhibiting ookinete association with the midgut surface. J Exp Biol (2001) 0.96
Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease. J Infect Dis (1995) 0.96
Enhanced mosquito blood-finding success on parasitemic hosts: evidence for vector-parasite mutualism. Proc Natl Acad Sci U S A (1985) 0.95
The effect of treating with anti-interleukin-1 receptor antibody on the course of experimental murine cutaneous leishmaniasis. Parasite Immunol (1994) 0.95
Ixodes dammini: salivary anaphylatoxin inactivating activity. Exp Parasitol (1986) 0.95
Antioxidant role of Rhodnius prolixus heme-binding protein. Protection against heme-induced lipid peroxidation. J Biol Chem (1995) 0.94
An avirulent lipophosphoglycan-deficient Leishmania major clone induces CD4+ T cells which protect susceptible BALB/c mice against infection with virulent L. major. Infect Immun (1993) 0.94
Salivary apyrase of Rhodnius prolixus. Kinetics and purification. Biochem J (1986) 0.92
Can transposable elements be used to drive disease refractoriness genes into vector populations? Parasitol Today (1992) 0.92
The salivary adenosine deaminase from the sand fly Lutzomyia longipalpis. Exp Parasitol (2000) 0.91
Indomethacin treatment slows disease progression and enhances a Th1 response in susceptible BALB/c mice infected with Leishmania major. Parasite Immunol (1999) 0.91
A heme-binding protein from hemolymph and oocytes of the blood-sucking insect, Rhodnius prolixus. Isolation and characterization. J Biol Chem (1995) 0.91
Differential distribution of immature Ixodes dammini (Acari: Ixodidae) on rodent hosts. J Parasitol (1989) 0.90
The invertebrate growth factor/CECR1 subfamily of adenosine deaminase proteins. Gene (2001) 0.90
Malaria vaccines: lessons from field trials. Cad Saude Publica (2004) 0.90
Reversion to virulence in Leishmania major correlates with expression of surface lipophosphoglycan. Mol Biochem Parasitol (1993) 0.89
Leishmania amazonensis: sensitivity of different promastigote morphotypes to salivary gland homogenates of the sand fly Lutzomyia longipalpis. Exp Parasitol (1995) 0.88
Virulent or avirulent (dhfr-ts-) Leishmania major elicit predominantly a type-1 cytokine response by human cells in vitro. Clin Exp Immunol (2000) 0.87
Blood-feeding strategy of Haematobia irritans (Diptera: Muscidae). J Med Entomol (1998) 0.87