|
1
|
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions.
|
Methods
|
2012
|
1.75
|
|
2
|
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124.
|
Proc Natl Acad Sci U S A
|
2010
|
1.64
|
|
3
|
Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter.
|
Chem Biol
|
2012
|
1.14
|
|
4
|
Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase.
|
J Med Chem
|
2012
|
1.14
|
|
5
|
Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay.
|
Mol Cancer Ther
|
2009
|
1.11
|
|
6
|
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
|
J Med Chem
|
2009
|
1.05
|
|
7
|
Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.
|
J Med Chem
|
2011
|
1.05
|
|
8
|
Non-iminosugar glucocerebrosidase small molecule chaperones.
|
Medchemcomm
|
2011
|
0.87
|
|
9
|
Discovery of a novel general anesthetic chemotype using high-throughput screening.
|
Anesthesiology
|
2015
|
0.78
|
|
10
|
Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A.
|
Chem Biol
|
2013
|
0.77
|
|
11
|
Discovery of a novel noniminosugar acid α glucosidase chaperone series.
|
J Med Chem
|
2012
|
0.76
|
|
12
|
High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.
|
J Biomol Screen
|
2012
|
0.75
|
|
13
|
Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.
|
PLoS One
|
2016
|
0.75
|