Giuseppina Tesco

Author PubWeight™ 16.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 BACE is degraded via the lysosomal pathway. J Biol Chem 2005 1.53
2 Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum Mol Genet 2009 1.46
3 Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion. J Biol Chem 2006 1.26
4 Ubiquitin regulates GGA3-mediated degradation of BACE1. J Biol Chem 2010 1.16
5 Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1. J Biol Chem 2003 1.12
6 Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease. Neurodegener Dis 2012 1.10
7 Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy. Circulation 2010 1.08
8 Molecular mechanisms of cognitive dysfunction following traumatic brain injury. Front Aging Neurosci 2013 1.05
9 Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1. J Neurosci 2012 0.95
10 Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab 2010 0.93
11 Hypocapnia induces caspase-3 activation and increases Abeta production. Neurodegener Dis 2004 0.91
12 Natural amyloid-β oligomers acutely impair the formation of a contextual fear memory in mice. PLoS One 2012 0.85
13 BACE1 protein endocytosis and trafficking are differentially regulated by ubiquitination at lysine 501 and the Di-leucine motif in the carboxyl terminus. J Biol Chem 2012 0.84
14 Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1. Cell Signal 2008 0.79
15 New advances in Alzheimer's disease: from biology to therapy. Curr Genomics 2007 0.75
16 Autophagy: a common road to perdition in acute brain injuries and Alzheimer's disease. J Neurochem 2012 0.75