Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis.

PubWeight™: 1.25‹?› | Rank: Top 10%

🔗 View Article (PMID 2019794)

Published in J Lab Clin Med on May 01, 1991

Authors

G D McLaren1, M H Nathanson, A Jacobs, D Trevett, W Thomson

Author Affiliations

1: Department of Veterans Affairs Medical Center, Fargo, North Dakota.

Articles citing this

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology (2015) 3.40

Genes that modify the hemochromatosis phenotype in mice. J Clin Invest (2000) 1.99

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man. J Exp Med (1996) 1.78

Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1. Proc Natl Acad Sci U S A (1999) 1.66

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. Proc Natl Acad Sci U S A (1999) 1.60

Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis. Gut (2004) 1.45

Regulation of intestinal non-haem iron absorption. Gut (1997) 1.18

Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study. Environ Health Perspect (2004) 1.15

Variants in iron metabolism genes predict higher blood lead levels in young children. Environ Health Perspect (2008) 1.14

Environmental manganese exposure in residents living near a ferromanganese refinery in Southeast Ohio: a pilot study. Neurotoxicology (2009) 1.13

Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation. Am J Physiol Gastrointest Liver Physiol (2006) 1.06

Pathophysiology of hereditary hemochromatosis. Semin Liver Dis (2005) 1.01

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis. Proc Natl Acad Sci U S A (2002) 1.01

Duodenal expression of iron transport molecules in untreated haemochromatosis subjects. Gut (2003) 0.95

Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse. Proc Natl Acad Sci U S A (2002) 0.93

Interactions between peripheral blood CD8 T lymphocytes and intestinal epithelial cells (iEC). Clin Exp Immunol (1998) 0.88

Telomere length and elevated iron: the influence of phenotype and HFE genotype. Am J Hematol (2013) 0.78

Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study. Hematology Am Soc Hematol Educ Program (2009) 0.78

Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation. Can J Gastroenterol (2012) 0.76

HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: a genotype-stratified cohort study of hemochromatosis in Australian women. J Gastroenterol Hepatol (2016) 0.75

Inherited liver diseases in adults. West J Med (1995) 0.75

Clinical-Pathological Conference Series from the Medical University of Graz : Case No 159: 52-year-old patient with psoriasis and arthralgia of the finger joints. Wien Klin Wochenschr (2016) 0.75

Articles by these authors

Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. Br Med J (1972) 4.60

Ferritin in serum. Clinical and biochemical implications. N Engl J Med (1975) 4.51

An immunoradiometric assay for ferritin in the serum of normal subjects and patients with iron deficiency and iron overload. J Clin Pathol (1972) 4.42

Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol (1993) 3.33

Calcium and Phosphorus Deficiencies in Poor Dietary. Br Med J (1938) 3.33

AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation (2001) 2.79

Percutaneous coronary intervention in the current era compared with 1985-1986: the National Heart, Lung, and Blood Institute Registries. Circulation (2000) 2.65

Susceptibility to melanoma: influence of skin type and polymorphism in the melanocyte stimulating hormone receptor gene. J Invest Dermatol (1998) 2.37

Type III InsP3 receptor channel stays open in the presence of increased calcium. Nature (1998) 2.26

The Arthritis and Rheumatism Council's National Repository of Family Material: pedigrees from the first 100 rheumatoid arthritis families containing affected sibling pairs. Br J Rheumatol (1994) 2.14

Current spectrum of cardiogenic shock and effect of early revascularization on mortality. Results of an International Registry. SHOCK Registry Investigators. Circulation (1995) 2.07

Low molecular weight intracellular iron transport compounds. Blood (1977) 2.02

Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis (2008) 2.01

Defect of cell-mediated immunity in patients with iron-deficiency anaemia. Lancet (1972) 2.01

A system for data processing in haematology. J Clin Pathol (1974) 1.95

Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas. Lancet (2001) 1.94

Mannose-binding protein gene polymorphism in systemic lupus erythematosus. Arthritis Rheum (1995) 1.94

Role in host cell invasion of Trypanosoma cruzi-induced cytosolic-free Ca2+ transients. J Exp Med (1994) 1.84

Trial of strategy for reducing the use of laboratory tests. Br Med J (Clin Res Ed) (1986) 1.82

Precision of automatic measurements of pigmented skin lesion parameters with a MelaFind(TM) multispectral digital dermoscope. Melanoma Res (2000) 1.78

The influence of diet upon ketonaemia in pregnant ewes. J Physiol (1938) 1.77

Quality assurance in general practice: the state of the art in Europe. Fam Pract (1994) 1.75

The characteristics of ferritin from human tissues, serum and blood cells. Clin Sci Mol Med (1975) 1.75

Isolated rat hepatocytes can signal to other hepatocytes and bile duct cells by release of nucleotides. Proc Natl Acad Sci U S A (1996) 1.69

T-DNA integration patterns in co-transformed plant cells suggest that T-DNA repeats originate from co-integration of separate T-DNAs. Plant J (1997) 1.64

The pharmacogenetics of methotrexate. Rheumatology (Oxford) (2007) 1.63

The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse macrophages. Destruction, survival, recovery. J Immunol (1993) 1.62

Population genetics of rheumatoid arthritis. Rheum Dis Clin North Am (1992) 1.61

Iron metabolism, sickle cell disease, and response to cyanate. Blood (1975) 1.60

Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector. Ultramicroscopy (2009) 1.60

Polymyalgia rheumatica can be distinguished from late onset rheumatoid arthritis at baseline: results of a 5-yr prospective study. Rheumatology (Oxford) (2008) 1.60

FMS mutations in myelodysplastic, leukemic, and normal subjects. Proc Natl Acad Sci U S A (1990) 1.58

HLA-DRB1*0401/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity. J Rheumatol (1995) 1.58

Serum ferritin in acute leukaemia at presentation and during remission. Br Med J (1975) 1.57

The measurement of reticuloendothelial iron release using iron-dextran. Br J Haematol (1971) 1.53

RANTES role in rheumatoid arthritis. Lancet (1994) 1.51

Cerebral hemodynamic response to the introduction of desflurane: A comparison with sevoflurane. Anesth Analg (2000) 1.50

Local anaesthetics and adjuvants--future developments. Anaesthesia (2010) 1.49

Ferritin synthesis in normal and leukaemic leukocytes. Nature (1974) 1.48

Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis. Ann Rheum Dis (2007) 1.47

Nuclear and cytosolic calcium are regulated independently. Proc Natl Acad Sci U S A (2003) 1.46

Epithelial Overgrowths and Diverticula. Br Med J (1937) 1.45

A second isolate of HTLV-II associated with atypical hairy-cell leukemia. N Engl J Med (1986) 1.44

Replacing 99Tcm-DMSA for renal imaging? Nucl Med Commun (1992) 1.43

On Black Expectoration, and the Deposition of Black Matter in the Lungs, particularly as occurring in Coal miners, &c. Med Chir Trans (1837) 1.41

Maternal-fetal HLA incompatibility and the course of inflammatory arthritis during pregnancy. J Rheumatol (2000) 1.41

A novel 5'-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum (2001) 1.41

The DNA sequences of T-DNA junctions suggest that complex T-DNA loci are formed by a recombination process resembling T-DNA integration. Plant J (1999) 1.41

A rapid method for the detection of ferritin in serum. J Clin Pathol (1971) 1.41

RAS and FMS mutations following cytotoxic therapy for childhood acute lymphoblastic leukaemia. Leukemia (1995) 1.39

Rivaroxaban for thromboembolism prophylaxis after orthopaedic surgery. Anaesthesia (2010) 1.39

Long-term outcomes in patients with schizophrenia treated with risperidone long-acting injection or oral antipsychotics in Spain: results from the electronic Schizophrenia Treatment Adherence Registry (e-STAR). Eur Psychiatry (2009) 1.38

Validation of the minimal citrate tube fill volume for routine coagulation tests on ACL TOP 500 CTS®. Int J Lab Hematol (2013) 1.38

HMPAO SPET and FDG PET in Alzheimer's disease and vascular dementia: comparison of perfusion and metabolic pattern. Eur J Nucl Med (1994) 1.38

Evolutionary divergence of genes for ornithine and aspartate carbamoyl-transferases--complete sequence and mode of regulation of the Escherichia coli argF gene; comparison of argF with argI and pyrB. Nucleic Acids Res (1984) 1.37

Ferritinaemia in leukaemia and Hodgkin's disease. Br J Cancer (1973) 1.37

Properties of human tissue isoferritins. Biochem J (1978) 1.37

The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford) (2006) 1.36

Myelodysplastic syndromes: pathogenesis, functional abnormalities, and clinical implications. J Clin Pathol (1985) 1.36

Haemoglobin estimation: a comparison of different techniques. Br Med J (1966) 1.35

The performance of anti-cyclic citrullinated peptide antibodies in predicting the severity of radiologic damage in inflammatory polyarthritis: results from the Norfolk Arthritis Register. Arthritis Rheum (2007) 1.35

Association between duration of symptoms and severity of disease at first presentation to paediatric rheumatology: results from the Childhood Arthritis Prospective Study. Rheumatology (Oxford) (2008) 1.33

Ferritin in normal erythrocytes, lymphocytes, polymorphs, and monocytes. Br J Haematol (1974) 1.32

Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke. Stroke (2004) 1.28

Molecular imaging of gene therapy for cancer. Gene Ther (2004) 1.28

The influence of HLA-DRB1 alleles and rheumatoid factor on disease outcome in an inception cohort of patients with early inflammatory arthritis. Arthritis Rheum (1999) 1.28

Nomenclature for factors of the dog major histocompatibility system (DLA), 2000: Second report of the ISAG DLA Nomenclature Committee. Tissue Antigens (2001) 1.27

Are certain HLA haplotypes responsible for low testosterone levels in males? Dis Markers (1989) 1.26

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. Hum Gene Ther (1997) 1.26

Human preleukaemia: do we have a model? Br J Cancer (1987) 1.25

Studies in desferrioxamine and ferrioxamine metabolism in normal and iron-loaded subjects. Br J Haematol (1979) 1.25

Serial [18F] fluorodeoxyglucose positron emission tomography after human neuronal implantation for stroke. Neurosurgery (2001) 1.25

Ferrokinetics and erythropoiesis in man: the measurement of effective erythropoiesis, ineffective erythropoiesis and red cell lifespan using 59Fe. Br J Haematol (1975) 1.25

HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis. J Rheumatol (2001) 1.25

Iron uptake by Chang cells from transferrin, nitriloacetate and citrate complexes: the effects of iron-loading and chelation with desferrioxamine. Biochim Biophys Acta (1978) 1.25

Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. Am J Physiol Gastrointest Liver Physiol (2001) 1.24

Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration. Gut (1975) 1.24

The purification and properties of ferritin from human serum. Biochem J (1976) 1.24

Binding of serum ferritin to concanavalin A: patients with homozygous beta thalassaemia and transfusional iron overload. Br J Haematol (1980) 1.23

Improved performance of seroconversion with a 4th generation HIV antigen/antibody assay. J Virol Methods (1999) 1.22

Nomenclature for factors of the dog major histocompatibility system (DLA), 1998. First report of the ISAG DLA Nomenclature Committee. International Society for Animals Genetics. Tissue Antigens (1999) 1.22

Clinical characteristics of patients younger than 60 years with mitral anular calcium: comparison with age- and sex-matched control subjects. Am J Cardiol (1984) 1.22

Patterns of failure in endometrial carcinoma stage IB grade 3 and IC patients treated with postoperative vaginal vault brachytherapy. Gynecol Oncol (1999) 1.21

Transferrin iron, chelatable iron and ferritin in idiopathic haemochromatosis. Br J Haematol (1974) 1.20

Absence of rheumatoid arthritis in a rural Nigerian population. J Rheumatol (1993) 1.19

Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis. Genes Immun (2003) 1.18

AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 update. A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. J Am Coll Cardiol (2001) 1.17

Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis. Arthritis Rheum (2001) 1.17

Erythrocyte ferritin in normal subjects and patients with abnormal iron metabolism. Br J Haematol (1983) 1.15

Biotin labeling of red cells in the measurement of red cell volume in preterm infants. Pediatr Res (1990) 1.15

Proinflammatory cytokines inhibit secretion in rat bile duct epithelium. Gastroenterology (2001) 1.15

Expression and subcellular localization of the ryanodine receptor in rat pancreatic acinar cells. Biochem J (1999) 1.15

Exploring the genetic susceptibility of chronic widespread pain: the tender points in genetic association studies. Rheumatology (Oxford) (2008) 1.14

Arylhydrocarbon hydroxylase activity in lymphocytes of patients with psoriasis. Lancet (1980) 1.14

The conjugal intermediate of plasmid RSF1010 inhibits Agrobacterium tumefaciens virulence and VirB-dependent export of VirE2. J Bacteriol (1998) 1.14

Ferritin in blood cells from normal subjects and patients with leukaemia. Br J Haematol (1974) 1.13

Iron overload--clinical and pathologic aspects. Semin Hematol (1977) 1.13