Howard Colman

Author PubWeight™ 100.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006 21.66
2 A randomized trial of bevacizumab for newly diagnosed glioblastoma. N Engl J Med 2014 9.19
3 The transcriptional network for mesenchymal transformation of brain tumours. Nature 2009 8.44
4 Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med 2015 5.71
5 FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell 2011 3.58
6 Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res 2005 3.10
7 Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol 2007 3.07
8 Retracted Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig2-positive glioma tumor-initiating cells. Cancer Res 2013 2.75
9 The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev 2011 2.48
10 Retracted Glioma-associated cancer-initiating cells induce immunosuppression. Clin Cancer Res 2010 2.24
11 Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J Natl Cancer Inst 2007 2.23
12 Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway. Mol Cancer Ther 2010 2.00
13 Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res 2006 1.91
14 YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma. Clin Cancer Res 2005 1.81
15 MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol 2009 1.69
16 The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors. Cancer 2005 1.34
17 IDH1 and IDH2 mutations in gliomas. Curr Neurol Neurosci Rep 2013 1.32
18 Glioma biology and molecular markers. Cancer Treat Res 2015 1.24
19 A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies. Neuro Oncol 2008 1.23
20 Exploratory analysis of the copy number alterations in glioblastoma multiforme. PLoS One 2008 1.17
21 Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells. J Proteome Res 2010 1.09
22 Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma. J Neurooncol 2009 1.07
23 A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells. Stem Cells 2014 1.07
24 Tie2/TEK modulates the interaction of glioma and brain tumor stem cells with endothelial cells and promotes an invasive phenotype. Oncotarget 2010 1.05
25 Effective elimination of cancer stem cells by a novel drug combination strategy. Stem Cells 2013 1.04
26 Phase 2 trial design in neuro-oncology revisited: a report from the RANO group. Lancet Oncol 2012 1.01
27 REST regulates oncogenic properties of glioblastoma stem cells. Stem Cells 2012 1.00
28 Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway. J Neurooncol 2012 0.95
29 Isolation and perivascular localization of mesenchymal stem cells from mouse brain. Neurosurgery 2010 0.93
30 A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma. Neuro Oncol 2010 0.93
31 Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme. Neuro Oncol 2008 0.93
32 ELTD1, a potential new biomarker for gliomas. Neurosurgery 2013 0.91
33 Glycomic and transcriptomic response of GSC11 glioblastoma stem cells to STAT3 phosphorylation inhibition and serum-induced differentiation. J Proteome Res 2010 0.90
34 A practical review of prognostic correlations of molecular biomarkers in glioblastoma. Neurosurg Focus 2015 0.90
35 Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells. Neoplasia 2013 0.88
36 Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma. J Neurooncol 2010 0.87
37 Experimental validation of 5 in-silico predicted glioma biomarkers. Neuro Oncol 2013 0.86
38 Brain tumor stem cells. Curr Probl Cancer 2008 0.85
39 Incorporation of biomarker assessment in novel clinical trial designs: personalizing brain tumor treatments. Curr Oncol Rep 2011 0.83
40 Polar lipid remodeling and increased sulfatide expression are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan. Glycoconj J 2009 0.82
41 Phase I trial of verubulin (MPC-6827) plus carboplatin in patients with relapsed glioblastoma multiforme. J Neurooncol 2012 0.79
42 Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas. Neurosurg Focus 2015 0.79
43 Phase 1/1b study of lonafarnib and temozolomide in patients with recurrent or temozolomide refractory glioblastoma. Cancer 2013 0.79
44 Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma. Cancer 2011 0.78
45 Retraction: Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig 2-positive glioma tumor-initiating cells. Cancer Res 2014 0.75
46 Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report. Case Rep Oncol 2013 0.75
47 Medulloblastoma: molecular classifications and prognostic associations. Oncology (Williston Park) 2012 0.75