Claude Leclerc

Author PubWeight™ 108.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat Med 2003 5.97
2 Neonatal adaptive immunity comes of age. Nat Rev Immunol 2004 5.31
3 Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. Immunity 2009 3.52
4 Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infect Immun 2006 2.56
5 Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP. PLoS Pathog 2008 1.94
6 Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity. J Immunol 2002 1.88
7 Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Nat Genet 2013 1.67
8 Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. Immunity 2005 1.66
9 Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity. J Biol Chem 2005 1.64
10 Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system. J Immunol 2005 1.61
11 An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis. Infect Immun 2006 1.51
12 CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules. J Exp Med 2002 1.49
13 Developing a model of recovery in mental health. BMC Health Serv Res 2009 1.40
14 Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation. Mol Microbiol 2012 1.39
15 Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells. J Exp Med 2007 1.39
16 Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines. Bioconjug Chem 2005 1.36
17 Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood 2008 1.32
18 Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6. Infect Immun 2004 1.31
19 Ontogeny and innate properties of neonatal dendritic cells. Blood 2003 1.30
20 High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection. Infect Immun 2006 1.26
21 A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates. Cancer Res 2004 1.26
22 Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J Immunol 2007 1.25
23 Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis. Schizophr Res 2008 1.20
24 CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family. Infect Immun 2003 1.18
25 The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences. Cancer Res 2012 1.17
26 Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation. Blood 2004 1.17
27 In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway. J Immunol 2003 1.16
28 Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain. J Biol Chem 2003 1.15
29 Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. J Infect Dis 2004 1.13
30 Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system. Cancer Res 2007 1.11
31 ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis. J Infect Dis 2010 1.09
32 The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo. J Immunol 2007 1.08
33 Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming. J Immunol 2004 1.06
34 Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells. Vaccine 2008 1.05
35 TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help. Blood 2007 1.04
36 Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein. Cancer Res 2005 1.03
37 Group cognitive behavior therapy or social skills training for individuals with a recent onset of psychosis? Results of a randomized controlled trial. J Nerv Ment Dis 2008 1.01
38 Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential. Cell Host Microbe 2012 1.01
39 Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells. J Immunol 2002 1.01
40 Regulatory B and T cells in infections. Microbes Infect 2008 1.01
41 Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis. PLoS One 2008 1.00
42 Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector. Clin Vaccine Immunol 2007 0.98
43 Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells. Biochemistry 2005 0.98
44 Virus-like particles: a new family of delivery systems. Expert Rev Vaccines 2002 0.96
45 New tools for antigen delivery to the MHC class I pathway. Trends Immunol 2004 0.96
46 Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids. Infect Immun 2005 0.95
47 Recognition of mycobacterial antigens delivered by genetically detoxified Bordetella pertussis adenylate cyclase by T cells from cattle with bovine tuberculosis. Infect Immun 2004 0.93
48 Delivery of a MalE CD4(+)-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase. Infect Immun 2002 0.92
49 MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion. J Leukoc Biol 2013 0.90
50 Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis. J Virol 2005 0.90
51 The adenylate cyclase toxin from Bordetella pertussis--a novel promising vehicle for antigen delivery to dendritic cells. Int J Med Microbiol 2004 0.90
52 The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization. Int Immunol 2003 0.89
53 Carbohydrate antigens: synthesis aspects and immunological applications in cancer. Mini Rev Med Chem 2006 0.89
54 In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells. Eur J Immunol 2002 0.88
55 CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles. Virology 2003 0.88
56 Adenylate cyclase toxin translocates across target cell membrane without forming a pore. Mol Microbiol 2010 0.88
57 Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo. Int Immunol 2006 0.87
58 Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences. Vaccine 2002 0.87
59 Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres. J Immunol 2004 0.86
60 Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses. J Biol Chem 2010 0.86
61 The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. Cancer Res 2009 0.86
62 Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes. Vaccine 2002 0.85
63 The shift of Th1 to Th2 immunodominance associated with the chronicity of Mycobacterium bovis bacille Calmette-Guérin infection does not affect the memory response. J Immunol 2003 0.85
64 Personality characteristics and attachment in first episode psychosis: impact on social functioning. J Nerv Ment Dis 2007 0.85
65 Fetal spleen stroma drives macrophage commitment. Development 2006 0.85
66 Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer. Cancer Immunol Immunother 2013 0.85
67 Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal. J Immunol 2005 0.85
68 Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin. Int J Cancer 2011 0.85
69 Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. PLoS One 2013 0.85
70 Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial antigens by MHC molecules. J Immunol 2007 0.85
71 Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes. Int Immunol 2003 0.85
72 Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores. PLoS Pathog 2012 0.85
73 Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination. Glycobiology 2006 0.84
74 Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells. J Virol 2006 0.84
75 Pivotal role of plasmacytoid dendritic cells in inflammation and NK-cell responses after TLR9 triggering in mice. Blood 2012 0.84
76 Induction of anti-Tat neutralizing antibodies by the CyaA vector targeting dendritic cells: influence of the insertion site and of the delivery of multicopies of the dominant Tat B-cell epitope. Vaccine 2010 0.82
77 Group CBT for early psychosis--are there still benefits one year later? Int J Group Psychother 2012 0.82
78 Change in jumping to conclusions linked to change in delusions in early psychosis. Schizophr Res 2013 0.81
79 Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood 2010 0.81
80 Do people with a first episode of psychosis differ in personality profiles? Schizophr Res 2006 0.81
81 Spirituality and religion in outpatients with schizophrenia: a multi-site comparative study of Switzerland, Canada, and the United States. Int J Psychiatry Med 2012 0.81
82 The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells. Eur J Immunol 2011 0.80
83 Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses. Vaccine 2012 0.79
84 Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen. Bioorg Med Chem Lett 2004 0.78
85 Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions. J Neuroimmunol 2008 0.78
86 Complexes of streptavidin-fused antigens with biotinylated antibodies targeting receptors on dendritic cell surface: a novel tool for induction of specific T-cell immune responses. Mol Biotechnol 2012 0.78
87 Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates. Vaccine 2006 0.78
88 Do personality traits matter when choosing a group therapy for early psychosis? Psychol Psychother 2011 0.77
89 Personality traits in early psychosis: relationship with symptom and coping treatment outcomes. Early Interv Psychiatry 2010 0.76
90 The process of recovery of people with mental illness: the perspectives of patients, family members and care providers: part 1. BMC Health Serv Res 2010 0.76
91 Religion and spirituality: how clinicians in quebec and geneva cope with the issue when faced with patients suffering from chronic psychosis. Community Ment Health J 2009 0.76
92 Intrusion errors in explicit memory: their differential relationship with clinical and social outcome in chronic schizophrenia. Cogn Neuropsychiatry 2007 0.76
93 Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo. Vaccine 2004 0.76
94 Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis. Vaccine 2010 0.75
95 Challenges and issues in new vaccine development. Trends Immunol 2002 0.75
96 [Analysis of in vitro delivering CD8+ T epitopes by attenuated bacteria]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 0.75
97 [In-vivo dynamic changes of antigen presenting cells infected with recombinant attenuated Salmonella typhimurium expressing green fluorescent protein]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 0.75
98 [Group interventions for people with refractory psychosis]. Sante Ment Que 2005 0.75
99 [Reaction of nurses to telephone clients with borderline personality disorder]. Perspect Infirm 2012 0.75
100 [Evaluation of the mental condition. How are you today?]. Perspect Infirm 2011 0.75