Sarcopenia: characteristics, mechanisms and functional significance.

Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front Physiol (2012) 2.37

A prospective study of frailty in nephrology-referred patients with CKD. Am J Kidney Dis (2012) 1.90

New horizons in the pathogenesis, diagnosis and management of sarcopenia. Age Ageing (2013) 1.63

In vivo and in vitro evidence that intrinsic upper- and lower-limb skeletal muscle function is unaffected by ageing and disuse in oldest-old humans. Acta Physiol (Oxf) (2015) 1.52

C57BL/6 neuromuscular healthspan scoring system. J Gerontol A Biol Sci Med Sci (2013) 1.38

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing. Nutr Metab (Lond) (2011) 1.28

Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management. Orphanet J Rare Dis (2012) 1.27

Age-associated alterations of the neuromuscular junction. Exp Gerontol (2010) 1.26

Muscle stem cells contribute to myofibres in sedentary adult mice. Nat Commun (2015) 1.23

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise. J Appl Physiol (1985) (2011) 1.11

Sarcopenia is independently associated with cardiovascular disease in older Korean adults: the Korea National Health and Nutrition Examination Survey (KNHANES) from 2009. PLoS One (2013) 1.08

Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism. Aging (Albany NY) (2012) 1.05

National Cancer Institute-National Heart, Lung and Blood Institute/pediatric Blood and Marrow Transplant Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: long-term organ damage and dysfunction. Biol Blood Marrow Transplant (2011) 1.01

Characterizing upper limb muscle volume and strength in older adults: a comparison with young adults. J Biomech (2011) 0.99

Serological muscle loss biomarkers: an overview of current concepts and future possibilities. J Cachexia Sarcopenia Muscle (2012) 0.99

Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia. Int J Biochem Cell Biol (2013) 0.97

Structure and function of human muscle fibres and muscle proteome in physically active older men. J Physiol (2017) 0.96

Enhanced force production in old age is not a far stretch: an investigation of residual force enhancement and muscle architecture. Physiol Rep (2013) 0.96

Terminal Schwann cells participate in neuromuscular synapse remodeling during reinnervation following nerve injury. J Neurosci (2014) 0.95

The effect of physiological stimuli on sarcopenia; impact of Notch and Wnt signaling on impaired aged skeletal muscle repair. Int J Biol Sci (2012) 0.94

Diagnostic measures for sarcopenia and bone mineral density. Osteoporos Int (2013) 0.92

Association between Sarcopenia, Bone Density, and Health-Related Quality of Life in Korean Men. Korean J Fam Med (2013) 0.92

Total daily activity declines more rapidly with increasing age in older adults. Arch Gerontol Geriatr (2013) 0.92

Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation. PLoS One (2013) 0.90

Aging influences adaptations of the neuromuscular junction to endurance training. Neuroscience (2011) 0.88

Altered activation of the antagonist muscle during practice compromises motor learning in older adults. J Neurophysiol (2014) 0.87

Temporal development of muscle atrophy in murine model of arthritis is related to disease severity. J Cachexia Sarcopenia Muscle (2013) 0.87

Proteomics of muscle chronological ageing in post-menopausal women. BMC Genomics (2014) 0.86

Increased residual force enhancement in older adults is associated with a maintenance of eccentric strength. PLoS One (2012) 0.86

Age-related greater Achilles tendon compliance is not associated with larger plantar flexor muscle fascicle strains in senior women. J Appl Physiol (1985) (2014) 0.86

Murine models of atrophy, cachexia, and sarcopenia in skeletal muscle. Biochim Biophys Acta (2013) 0.86

Optimal therapy of type 2 diabetes: a controversial challenge. Aging (Albany NY) (2014) 0.85

Human neuromuscular structure and function in old age: A brief review. J Sport Health Sci (2013) 0.85

The pleiotropic effect of physical exercise on mitochondrial dynamics in aging skeletal muscle. Oxid Med Cell Longev (2015) 0.85

Limitations to exercise in female centenarians: evidence that muscular efficiency tempers the impact of failing lungs. Age (Dordr) (2012) 0.85

Sarcopenia: An emphasis on occlusion training and dietary protein. Hippokratia (2011) 0.85

Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people. Cell Stress Chaperones (2011) 0.85

Effects of Three Types of Exercise Interventions on Healthy Old Adults' Gait Speed: A Systematic Review and Meta-Analysis. Sports Med (2015) 0.84

Physical predictors of cognitive performance in healthy older adults: a cross-sectional analysis. PLoS One (2013) 0.84

Age-related differences in diffusion tensor indices and fiber architecture in the medial and lateral gastrocnemius. J Magn Reson Imaging (2014) 0.84

Age and grip strength predict hand dexterity in adults. PLoS One (2015) 0.83

miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. Genes Dev (2015) 0.83

Androgen effects on skeletal muscle: implications for the development and management of frailty. Asian J Androl (2014) 0.83

Muscle protein synthesis response to exercise training in obese, older men and women. Med Sci Sports Exerc (2012) 0.83

Endoplasmic reticulum stress in human skeletal muscle: any contribution to sarcopenia? Front Physiol (2013) 0.83

Age-associated differences in triceps surae muscle composition and strength - an MRI-based cross-sectional comparison of contractile, adipose and connective tissue. BMC Musculoskelet Disord (2014) 0.83

Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal. Am J Physiol Endocrinol Metab (2014) 0.82

TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice. Endocrinology (2016) 0.82

Protein carbonylation and heat shock proteins in human skeletal muscle: relationships to age and sarcopenia. J Gerontol A Biol Sci Med Sci (2014) 0.81

Association of body composition with sarcopenic obesity in elderly women. Int J Gen Med (2013) 0.81

The role of exercise capacity in the health and longevity of centenarians. Maturitas (2012) 0.81

Sarcopenia is associated with Framingham risk score in the Korean population: Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2011. J Geriatr Cardiol (2015) 0.80

Strength training-induced responses in older adults: attenuation of descending neural drive with age. Age (Dordr) (2015) 0.80

Effects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjects. Oncotarget (2015) 0.79

Explosive type of moderate-resistance training induces functional, cardiovascular, and molecular adaptations in the elderly. Age (Dordr) (2013) 0.79

The Instrumented Sit-to-Stand Test (iSTS) Has Greater Clinical Relevance than the Manually Recorded Sit-to-Stand Test in Older Adults. PLoS One (2016) 0.79

Metabolic Syndrome and Cardiovascular Disease after Hematopoietic Cell Transplantation: Screening and Preventive Practice Recommendations from the CIBMTR and EBMT. Biol Blood Marrow Transplant (2016) 0.78

Commentaries on Viewpoint: Muscle atrophy is not always sarcopenia. J Appl Physiol (1985) (2012) 0.78

The aromatic amino acid tryptophan stimulates skeletal muscle IGF1/p70s6k/mTor signaling in vivo and the expression of myogenic genes in vitro. Nutrition (2015) 0.78

Is co-contraction responsible for the decline in maximal knee joint torque in older males? Age (Dordr) (2014) 0.78

Hyperhomocysteinemia inhibits satellite cell regenerative capacity through p38 alpha/beta MAPK signaling. Am J Physiol Heart Circ Physiol (2015) 0.78

Sarcopenia and the analysis of body composition. Adv Nutr (2014) 0.78

Muscle wasting and cachexia in heart failure: mechanisms and therapies. Nat Rev Cardiol (2017) 0.78

Protein Supplementation Does Not Significantly Augment the Effects of Resistance Exercise Training in Older Adults: A Systematic Review. J Am Med Dir Assoc (2016) 0.78

Age-related structural changes in upper extremity muscle tissue in a nonhuman primate model. J Shoulder Elbow Surg (2015) 0.78

Age and muscle strength mediate the age-related biomechanical plasticity of gait. Eur J Appl Physiol (2016) 0.77

Interaction between bone and muscle in older persons with mobility limitations. Curr Pharm Des (2014) 0.77

Cardiometabolic risk in overweight subjects with or without relative fat-free mass deficiency: the Strong Heart Study. Nutr Metab Cardiovasc Dis (2013) 0.77

Longitudinal changes in insulin sensitivity, insulin secretion, beta cell function and glucose effectiveness during development of non-diabetic hyperglycemia in a Japanese population. Springerplus (2014) 0.77

Sarcopenic obesity and cognitive functioning: the mediating roles of insulin resistance and inflammation? Curr Gerontol Geriatr Res (2012) 0.76

Resistance Exercise to Prevent and Manage Sarcopenia and Dynapenia. Annu Rev Gerontol Geriatr (2016) 0.76

Age-Related Uptake of Heavy Metals in Human Spinal Interneurons. PLoS One (2016) 0.76

Maximal aerobic power and anaerobic capacity in cycling across the age spectrum in male master athletes. Eur J Appl Physiol (2016) 0.76

Analysis of postural control and muscular performance in young and elderly women in different age groups. Braz J Phys Ther (2015) 0.76

Sarcopenia and physical independence in older adults: the independent and synergic role of muscle mass and muscle function. J Cachexia Sarcopenia Muscle (2016) 0.75

Fiber type composition of the human quadratus plantae muscle: a comparison of the lateral and medial heads. J Foot Ankle Res (2014) 0.75

Sarcopenia in heart failure: mechanisms and therapeutic strategies. J Geriatr Cardiol (2016) 0.75

CIR-Myo News: Proceedings of the 2014 Spring Padua Muscle Days: Terme Euganee and Padova (Italy), April 3-5, 2014. Eur J Transl Myol (2014) 0.75

Calf-raise senior: a new test for assessment of plantar flexor muscle strength in older adults: protocol, validity, and reliability. Clin Interv Aging (2016) 0.75

Modeling age-related changes in muscle-tendon dynamics during cyclical contractions in the rat gastrocnemius. J Appl Physiol (1985) (2016) 0.75

Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine. J Cachexia Sarcopenia Muscle (2016) 0.75

The Need for Standardized Assessment of Muscle Quality in Skeletal Muscle Function Deficit and Other Aging-Related Muscle Dysfunctions: A Symposium Report. Front Physiol (2017) 0.75

Neuromuscular electrical stimulation leads to physiological gains enhancing postural balance in the pre-frail elderly. Physiol Rep (2015) 0.75

Analysis of effects of loading and postural demands on upper limb reaching in older adults using statistical parametric mapping. J Biomech (2016) 0.75

Sleep, Muscle Mass and Muscle Function in Older People. Dtsch Arztebl Int (2016) 0.75

Influence of aging on isometric muscle strength, fat-free mass and electromyographic signal power of the upper and lower limbs in women. Braz J Phys Ther (2014) 0.75

Urocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle. J Endocrinol (2014) 0.75

Age attenuates leucine oxidation after eccentric exercise. Int J Sports Med (2013) 0.75

Metabolic syndrome and cardiovascular disease following hematopoietic cell transplantation: screening and preventive practice recommendations from CIBMTR and EBMT. Bone Marrow Transplant (2016) 0.75

The impact of obesity on skeletal muscle strength and structure through adolescence to old age. Biogerontology (2015) 0.75

Factors Affecting Sarcopenia in Korean Adults by Age Groups. Osong Public Health Res Perspect (2017) 0.75

Bone strength and muscle properties in postmenopausal women with and without a recent distal radius fracture. Osteoporos Int (2015) 0.75

"Age-related effect of cell death on fiber morphology and number in tongue muscle". Muscle Nerve (2017) 0.75

Changes in muscle fascicles of tibialis anterior during anisometric contractions are not associated with motor-output variability of the ankle dorsiflexors in young and old adults. Eur J Appl Physiol (2010) 0.75

Measurement of muscle health in aging. Biogerontology (2017) 0.75

Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals. J Clin Endocrinol Metab (2017) 0.75

Tendon injury and tendinopathy: healing and repair. J Bone Joint Surg Am (2005) 3.55

Eccentric loading, shock-wave treatment, or a wait-and-see policy for tendinopathy of the main body of tendo Achillis: a randomized controlled trial. Am J Sports Med (2007) 2.77

Ultrasound as a primary evaluation tool of bone stress injuries in elite track and field athletes. Am J Sports Med (2012) 2.75

Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial. Am J Sports Med (2010) 2.26

Biochemical markers of muscular damage. Clin Chem Lab Med (2010) 2.25

Eccentric loading compared with shock wave treatment for chronic insertional achilles tendinopathy. A randomized, controlled trial. J Bone Joint Surg Am (2008) 2.24

IOC consensus paper on the use of platelet-rich plasma in sports medicine. Br J Sports Med (2010) 2.15

Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene. Knee Surg Sports Traumatol Arthrosc (2009) 2.15

Trauma and orthopaedic training in the United Kingdom. J Bone Joint Surg Am (2002) 2.11

Creatine kinase monitoring in sport medicine. Br Med Bull (2007) 2.00

How successful are current ankle replacements?: a systematic review of the literature. Clin Orthop Relat Res (2009) 2.00

Quantitative review of operative and nonoperative management of achilles tendon ruptures. Am J Sports Med (2002) 1.82

Equivalent clinical results of arthroscopic single-row and double-row suture anchor repair for rotator cuff tears: a randomized controlled trial. Am J Sports Med (2007) 1.81

Platelet-rich plasma or hyaluronate in the management of osteochondral lesions of the talus. Am J Sports Med (2012) 1.81

Surgery for ACL deficiency in patients over 50. Knee Surg Sports Traumatol Arthrosc (2010) 1.75

The effectiveness of arts-based interventions in medical education: a literature review. Med Educ (2011) 1.71

Evolving trauma and orthopedics training in the UK. J Surg Educ (2012) 1.69

Rating systems for evaluation of the elbow. Br Med Bull (2008) 1.68

Plantar fascia-specific stretching versus radial shock-wave therapy as initial treatment of plantar fasciopathy. J Bone Joint Surg Am (2010) 1.67

The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse. J Physiol (2007) 1.64

Bone regenerative medicine: classic options, novel strategies, and future directions. J Orthop Surg Res (2014) 1.64

Tenotomy versus tenodesis in the management of pathologic lesions of the tendon of the long head of the biceps brachii. Am J Sports Med (2008) 1.62

Low-energy extracorporeal shock wave therapy as a treatment for medial tibial stress syndrome. Am J Sports Med (2009) 1.55

Magnetic resonance imaging versus arthroscopy in the diagnosis of knee pathology, concentrating on meniscal lesions and ACL tears: a systematic review. Br Med Bull (2007) 1.52

Management of tendinopathy. Am J Sports Med (2009) 1.52

Achilles tendon disorders: etiology and epidemiology. Foot Ankle Clin (2005) 1.51

Selective Kirschner wiring for displaced distal radial fractures in children. Acta Orthop Traumatol Turc (2010) 1.45

Epidemiology of injury in child and adolescent sports: injury rates, risk factors, and prevention. Clin Sports Med (2008) 1.45

Eccentric calf muscle training in non-athletic patients with Achilles tendinopathy. J Sci Med Sport (2006) 1.44

The effect of magnetic resonance imaging scans on knee arthroscopy: randomized controlled trial. Arthroscopy (2007) 1.43

Platelet-rich plasma for managing pain and inflammation in osteoarthritis. Nat Rev Rheumatol (2013) 1.43

Appropriate informed consent, then randomization is the only ethical way! Arthroscopy (2007) 1.39

A European ACL register. Knee Surg Sports Traumatol Arthrosc (2007) 1.38

Signal or noise, a statistical perspective. Proc Natl Acad Sci U S A (2014) 1.36

Physiopathology of intratendinous calcific deposition. BMC Med (2012) 1.35

Histopathology of the supraspinatus tendon in rotator cuff tears. Am J Sports Med (2007) 1.29

Prevention of adhesions in surgery of the flexor tendons of the hand: what is the evidence? Br Med Bull (2009) 1.29

Tendon augmentation grafts: a systematic review. Br Med Bull (2010) 1.28

Genetics and epidemiology of idiopathic congenital talipes equinovarus. J Pediatr Orthop (2003) 1.27

Reinjury after acute posterior thigh muscle injuries in elite track and field athletes. Am J Sports Med (2010) 1.26

Posterior thigh muscle injuries in elite track and field athletes. Am J Sports Med (2010) 1.26

No advantages in repairing a type II superior labrum anterior and posterior (SLAP) lesion when associated with rotator cuff repair in patients over age 50: a randomized controlled trial. Am J Sports Med (2007) 1.25

Eccentric loading versus eccentric loading plus shock-wave treatment for midportion achilles tendinopathy: a randomized controlled trial. Am J Sports Med (2008) 1.25

Collagens, proteoglycans, MMP-2, MMP-9 and TIMPs in human achilles tendon rupture. Clin Orthop Relat Res (2008) 1.25

Calcific tendinopathy of the rotator cuff tendons. Sports Med Arthrosc (2011) 1.23

Home training, local corticosteroid injection, or radial shock wave therapy for greater trochanter pain syndrome. Am J Sports Med (2009) 1.22

Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study. Disabil Rehabil (2008) 1.19

Biomechanics and pathophysiology of overuse tendon injuries: ideas on insertional tendinopathy. Sports Med (2004) 1.19

Functional anatomy of the Achilles tendon. Knee Surg Sports Traumatol Arthrosc (2010) 1.19

Meniscectomy as a risk factor for knee osteoarthritis: a systematic review. Br Med Bull (2011) 1.18

Minimally invasive locked plating of distal tibia fractures is safe and effective. Clin Orthop Relat Res (2009) 1.17

Epidemiology of sprains of the lateral ankle ligament complex. Foot Ankle Clin (2006) 1.16

Extra-osseous osteochondroma-like soft tissue mass of the patello-femoral space. BMC Musculoskelet Disord (2006) 1.14

Acute muscle strain injuries: a proposed new classification system. Knee Surg Sports Traumatol Arthrosc (2012) 1.14

Femoroacetabular impingement syndrome management: arthroscopy or open surgery? Int Orthop (2011) 1.13

Protocol for the ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial: a pragmatic multi-centre randomised controlled trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults. BMC Musculoskelet Disord (2009) 1.13

Arthroscopic-assisted Broström-Gould for chronic ankle instability: a long-term follow-up. Am J Sports Med (2011) 1.11

Tissue engineered biological augmentation for tendon healing: a systematic review. Br Med Bull (2010) 1.10

Genetics and sports. Br Med Bull (2009) 1.09

Anti-inflammatory and Matrix Restorative Mechanisms of Platelet-Rich Plasma in Osteoarthritis: Letter to the Editor. Am J Sports Med (2014) 1.09

The anterior cruciate ligament remnant: to leave it or not? Arthroscopy (2013) 1.08

Shock wave therapy for chronic plantar fasciopathy. Br Med Bull (2007) 1.08

Microfracture for chondral defects of the talus: maintenance of early results at midterm follow-up. Knee Surg Sports Traumatol Arthrosc (2010) 1.08

Ankle instability. Sports Med Arthrosc (2009) 1.08

Upper cervical spine injuries: indications and limits of the conservative management in Halo vest. A systematic review of efficacy and safety. Injury (2010) 1.07

Ageing of human muscles and tendons. Disabil Rehabil (2008) 1.07

Rating scales for low back pain. Br Med Bull (2010) 1.07

Recurrent subluxation of the peroneal tendons. Sports Med (2006) 1.07

Anterior cruciate ligament tears: what we already know. Knee Surg Sports Traumatol Arthrosc (2012) 1.07

Remplissage repair--new frontiers in the prevention of recurrent shoulder instability: a 2-year follow-up comparative study. Am J Sports Med (2012) 1.07

Minimally invasive total knee arthroplasty: a systematic review. Orthop Clin North Am (2009) 1.07

Anteromedial portal versus transtibial drilling techniques in anterior cruciate ligament reconstruction: any clinical relevance? A retrospective comparative study. Arthroscopy (2013) 1.07

Management of the greater trochanteric pain syndrome: a systematic review. Br Med Bull (2011) 1.07

Metalloproteases and rotator cuff disease. J Shoulder Elbow Surg (2012) 1.06

Tendon healing and platelet-rich plasma therapies. Expert Opin Biol Ther (2010) 1.06

The effects of LIPUS on soft-tissue healing: a review of literature. Br Med Bull (2008) 1.05

Eosinophilic granuloma of the pediatric cervical spine. Spine (Phila Pa 1976) (2008) 1.05

Reconstruction of the anterior cruciate ligament with a patella-tendon-bone graft may lead to a permanent loss of bone mineral content due to decreased patellar tendon stiffness. Med Hypotheses (2005) 1.05

The best surgical treatment for type II fractures of the dens is still controversial. Clin Orthop Relat Res (2011) 1.05

Incidence and distribution of pediatric sport-related injuries. Clin J Sport Med (2006) 1.04

Achilles tendinopathy. Sports Med Arthrosc (2009) 1.04

Arthroscopic classification of acetabular rim labrochondral disease. Am J Sports Med (2013) 1.04

Medial patellofemoral ligament reconstruction: a new technique. BMC Musculoskelet Disord (2007) 1.04

High volume image guided injections in chronic Achilles tendinopathy. Disabil Rehabil (2008) 1.03

Management of Achilles tendinopathy by ultrasound-guided percutaneous tenotomy. Med Sci Sports Exerc (2002) 1.03

Inflammation in overuse tendon injuries. Sports Med Arthrosc (2011) 1.02

Percutaneous plating of the distal tibia. J Foot Ankle Surg (2004) 1.01

Tendinopathy of the tendon of the long head of the biceps. Sports Med Arthrosc (2011) 1.01

Acute ruptures of the achilles tendon. Sports Med Arthrosc (2009) 1.00

History and evolution in total ankle arthroplasty. Br Med Bull (2008) 1.00

The evidence of low-intensity pulsed ultrasound for in vitro, animal and human fracture healing. Br Med Bull (2011) 1.00

Hamstring exercises for track and field athletes: injury and exercise biomechanics, and possible implications for exercise selection and primary prevention. Br J Sports Med (2012) 0.99

The FIFA 11+ program is effective in preventing injuries in elite male basketball players: a cluster randomized controlled trial. Am J Sports Med (2012) 0.99

Arthroscopic management of chronic patellar tendinopathy. Am J Sports Med (2011) 0.99

Platelet-rich plasma for muscle injury and tendinopathy. Sports Med Arthrosc (2013) 0.99

Conservative management of tendinopathy: an evidence-based approach. Muscles Ligaments Tendons J (2012) 0.99

Tendinopathy and tendon injury: the future. Disabil Rehabil (2008) 0.99

Achilles tendon problems: not just an orthopaedic issue. Disabil Rehabil (2008) 0.99

Medial patellofemoral ligament reconstruction with a divergent patellar transverse 2-tunnel technique. Am J Sports Med (2011) 0.99

Joint pathology and platelet-rich plasma therapies. Expert Opin Biol Ther (2012) 0.98