Published in Org Biomol Chem on February 03, 2010
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter. Biochemistry (2005) 2.27
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter. J Am Chem Soc (2006) 1.93
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein. J Biol Chem (2009) 1.72
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4. Nucleic Acids Res (2007) 1.66
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene. J Am Chem Soc (2007) 1.53
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. J Am Chem Soc (2005) 1.40
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101. Proc Natl Acad Sci U S A (2003) 1.39
Haemogenic endocardium contributes to transient definitive haematopoiesis. Nat Commun (2013) 1.36
NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III(1). Mol Cancer Ther (2009) 1.19
Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene. Nucleic Acids Res (2008) 1.16
A novel cyclic enkephalin analogue with potent opioid antagonist activity. Bioorg Med Chem Lett (2004) 1.13
Ventricular constraint using the acorn cardiac support device reduces myocardial akinetic area in an ovine model of acute infarction. Circulation (2002) 1.13
Salient Region Detection via Integrating Diffusion-Based Compactness and Local Contrast. IEEE Trans Image Process (2015) 1.12
Enantioselective [3 + 2] cycloaddition of allenes to acrylates catalyzed by dipeptide-derived phosphines: facile creation of functionalized cyclopentenes containing quaternary stereogenic centers. J Am Chem Soc (2011) 1.12
Versatile enantioselective [3+2] cyclization between imines and allenoates catalyzed by dipeptide-based phosphines. Angew Chem Int Ed Engl (2011) 1.06
High diversity of human-pathogenic Enterocytozoon bieneusi genotypes in swine in northeast China. Parasitol Res (2014) 1.04
Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene. Nucleic Acids Res (2010) 1.04
Heterogeneous nuclear ribonucleoprotein K and nucleolin as transcriptional activators of the vascular endothelial growth factor promoter through interaction with secondary DNA structures. Biochemistry (2011) 1.03
Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells. Chem Res Toxicol (2010) 1.00
The suppression of prostate LNCaP cancer cells growth by Selenium nanoparticles through Akt/Mdm2/AR controlled apoptosis. Biomaterials (2011) 0.99
Synergistic toxicity of the environmental neurotoxins methylmercury and β-N-methylamino-L-alanine. Neuroreport (2012) 0.97
Highly enantioselective [3+2] annulation of Morita-Baylis-Hillman adducts mediated by L-threonine-derived phosphines: synthesis of 3-spirocyclopentene-2-oxindoles having two contiguous quaternary centers. Angew Chem Int Ed Engl (2011) 0.95
Oxygenation in cervical cancer and normal uterine cervix assessed using blood oxygenation level-dependent (BOLD) MRI at 3T. NMR Biomed (2012) 0.94
ZnO nanorods/Au hybrid nanocomposites for glucose biosensor. Biosens Bioelectron (2010) 0.93
Monitoring histone deacetylase inhibition in vivo: noninvasive magnetic resonance spectroscopy method. Mol Imaging (2008) 0.93
Asymmetric Mannich reaction of fluorinated ketoesters with a tryptophan-derived bifunctional thiourea catalyst. Angew Chem Int Ed Engl (2009) 0.93
Conversion of delta-, kappa- and mu-receptor selective opioid peptide agonists into delta-, kappa- and mu-selective antagonists. Life Sci (2003) 0.91
Highly enantioselective synthesis of 3,4-dihydropyrans through a phosphine-catalyzed [4+2] annulation of allenones and β,γ-unsaturated α-keto esters. J Am Chem Soc (2014) 0.91
Asymmetric synthesis of spiropyrazolones through phosphine-catalyzed [4+1] annulation. Angew Chem Int Ed Engl (2014) 0.89
Silencing of DLGAP5 by siRNA significantly inhibits the proliferation and invasion of hepatocellular carcinoma cells. PLoS One (2013) 0.89
Enantioselective Morita-Baylis-Hillman reaction of isatins with acrylates: facile creation of 3-hydroxy-2-oxindoles. Org Lett (2010) 0.89
Binding of G-quadruplex-interactive agents to distinct G-quadruplexes induces different biological effects in MiaPaCa cells. Nucleosides Nucleotides Nucleic Acids (2005) 0.89
An economic evaluation for prevention of diabetes mellitus in a developing country: a modelling study. BMC Public Health (2013) 0.89
Phosphine-catalyzed enantioselective γ-addition of 3-substituted oxindoles to 2,3-butadienoates and 2-butynoates: use of prochiral nucleophiles. Angew Chem Int Ed Engl (2014) 0.89
Targeting p53 as a therapeutic strategy in sensitizing TRAIL-induced apoptosis in cancer cells. Cancer Lett (2011) 0.88
Asymmetric catalysis with chiral primary amine-based organocatalysts. Chem Commun (Camb) (2009) 0.88
Interferon regulatory factor 3 deficiency leads to interleukin-17-mediated liver ischemia-reperfusion injury. Hepatology (2012) 0.88
Passive ventricular constraint to improve left ventricular function and mechanics in an ovine model of heart failure secondary to acute myocardial infarction. J Thorac Cardiovasc Surg (2003) 0.88
Chiral phosphine catalyzed asymmetric Michael addition of oxindoles. Angew Chem Int Ed Engl (2012) 0.87
Metadherin contributes to the pathogenesis of diffuse large B-cell lymphoma. PLoS One (2012) 0.87
Expressions of IL-18 and its binding protein in peripheral blood leukocytes and kidney tissues of lupus nephritis patients. Clin Rheumatol (2010) 0.87
Response enhancement of olfactory sensory neurons-based biosensors for odorant detection. J Zhejiang Univ Sci B (2009) 0.86
The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. Biochem Biophys Res Commun (2011) 0.86
The Brucella suis type IV secretion system assembles in the cell envelope of the heterologous host Agrobacterium tumefaciens and increases IncQ plasmid pLS1 recipient competence. Infect Immun (2006) 0.86
Cellular response and molecular mechanism of antitumor activity by leinamycin in MiaPaCa human pancreatic cancer cells. Anticancer Drugs (2004) 0.86
Asymmetric Michael addition mediated by novel cinchona alkaloid-derived bifunctional catalysts containing sulfonamides. Org Lett (2009) 0.86
Intercalated graphitic carbon nitride: a fascinating two-dimensional nanomaterial for an ultra-sensitive humidity nanosensor. Nanoscale (2014) 0.86
CCND1 G870A polymorphism with altered cyclin D1 transcripts expression is associated with the risk of glioma in a Chinese population. DNA Cell Biol (2012) 0.85
Primary amino acids: privileged catalysts in enantioselective organocatalysis. Org Biomol Chem (2008) 0.85
The direct asymmetric vinylogous aldol reaction of furanones with α-ketoesters: access to chiral γ-butenolides and glycerol derivatives. Angew Chem Int Ed Engl (2011) 0.85
Asymmetric [3+2] annulation of allenes with maleimides catalyzed by dipeptide-derived phosphines: facile creation of functionalized bicyclic cyclopentenes containing two tertiary stereogenic centers. Chem Commun (Camb) (2011) 0.84
Stereocontrolled creation of all-carbon quaternary stereocenters by organocatalytic conjugate addition of oxindoles to vinyl sulfone. Angew Chem Int Ed Engl (2010) 0.84
Simultaneous measurement of tissue oxygen level-dependent (TOLD) and blood oxygenation level-dependent (BOLD) effects in abdominal tissue oxygenation level studies. J Magn Reson Imaging (2013) 0.83
Active hydrogen species on TiO2 for photocatalytic H2 production. Phys Chem Chem Phys (2014) 0.83
Direct asymmetric aldol reactions between aldehydes and ketones catalyzed by L-tryptophan in the presence of water. Org Biomol Chem (2010) 0.83
"Carba"-analogues of fentanyl are opioid receptor agonists. J Med Chem (2010) 0.83
Factors affecting patient delay of diagnosis and completion of Direct Observation Therapy, Short-course (DOTS) among the migrant population in Shandong, China. Biosci Trends (2013) 0.83
Synthesis of Fe3O4@SiO2-Ag magnetic nanocomposite based on small-sized and highly dispersed silver nanoparticles for catalytic reduction of 4-nitrophenol. J Colloid Interface Sci (2012) 0.83
Primary amine/CSA ion pair: a powerful catalytic system for the asymmetric enamine catalysis. Org Lett (2011) 0.83
Layer-by-layer self-assembly of functionalized graphene nanoplates for glucose sensing in vivo integrated with on-line microdialysis system. Biosens Bioelectron (2011) 0.83
Size-controllable gold-platinum alloy nanoparticles on nine functionalized ionic-liquid surfaces and their application as electrocatalysts for hydrogen peroxide reduction. Chemistry (2011) 0.82
High expression and nuclear localization of β-catenin in diffuse large B-cell lymphoma. Mol Med Rep (2012) 0.82
Losartan, an angiotensin II type 1 receptor blocker, ameliorates cerebral ischemia-reperfusion injury via PI3K/Akt-mediated eNOS phosphorylation. Brain Res Bull (2012) 0.82
Tripterygium wilfordii Hook F (a traditional Chinese medicine) for primary nephrotic syndrome. Cochrane Database Syst Rev (2013) 0.81
Synthesis and characterization of a small analogue of the anticancer natural product leinamycin. Bioorg Med Chem (2012) 0.81
Diversity and recombination of human parechovirus in children with acute gastroenteritis in Guangzhou, China. J Med Virol (2014) 0.80
Tetramethylpyrazine analogue CXC195 protects against cerebral ischemia/reperfusion injury in the rat by an antioxidant action via inhibition of NADPH oxidase and iNOS expression. Pharmacology (2013) 0.80
Asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones via bifunctional thiourea-mediated intramolecular cyclization. Org Lett (2010) 0.80
DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences. Bioorg Med Chem (2012) 0.80
Using pure protein to build a multiple reaction monitoring mass spectrometry assay for targeted detection and quantitation. Methods Mol Biol (2013) 0.80
Chiral primary amine mediated conjugate addition of branched aldehydes to vinyl sulfone: asymmetric generation of quaternary carbon centers. Chem Commun (Camb) (2010) 0.80
From the Feist-Bénary reaction to organocatalytic domino Michael-alkylation reactions: asymmetric synthesis of 3(2H)-furanones. Chemistry (2011) 0.80
Asymmetric organocatalytic decarboxylative Mannich reaction using β-keto acids: A new protocol for the synthesis of chiral β-amino ketones. Beilstein J Org Chem (2012) 0.80
MYPT1 sustains centromeric cohesion and the spindle-assembly checkpoint. J Genet Genomics (2013) 0.79
Asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles via intramolecular trapping of chiral aza-ortho-xylylene. Chem Commun (Camb) (2013) 0.79
Antimicrobial activity and molecular mechanism of the CRES protein. PLoS One (2012) 0.79
The macrocycle of leinamycin imparts hydrolytic stability to the thiol-sensing 1,2-dithiolan-3-one 1-oxide unit of the natural product. Bioorg Med Chem Lett (2012) 0.79
Stathmin expression in glioma-derived microvascular endothelial cells: a novel therapeutic target. Oncol Rep (2011) 0.79
Room-temperature synthesis of flower-like BiOX (X═Cl, Br, I) hierarchical structures and their visible-light photocatalytic activity. Inorg Chem (2013) 0.79
Enantioselective Morita-Baylis-Hillman reaction promoted by L-threonine-derived phosphine-thiourea catalysts. Org Biomol Chem (2011) 0.79
Kinetic evidence of an apparent negative activation enthalpy in an organocatalytic process. Sci Rep (2013) 0.79
Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent. J Med Chem (2010) 0.79
Enantioselective construction of 3-hydroxy oxindoles via decarboxylative addition of β-ketoacids to isatins. Org Lett (2012) 0.79
Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: an organocatalytic access to chiral 3-fluoro-3-substituted oxindoles. Org Biomol Chem (2013) 0.79
High performance of a palladium phosphinooxazoline catalyst in the asymmetric arylation of cyclic N-sulfonyl ketimines. Angew Chem Int Ed Engl (2014) 0.78
Anti-inflammatory effect of acetylpuerarin on eicosanoid signaling pathway in primary rat astrocytes. J Mol Neurosci (2013) 0.78
Asymmetric allylic alkylation of isatin-derived Morita-Baylis-Hillman carbonates with nitroalkanes. Org Lett (2012) 0.78
Organocatalytic Michael addition of aldehydes to vinyl sulfones: enantioselective alpha-alkylations of aldehydes and their derivatives. Org Lett (2008) 0.78
Asymmetric aldol reactions catalyzed by tryptophan in water. Chem Commun (Camb) (2006) 0.78
Magnetically separable Fe3O4@SiO2@TiO2-Ag microspheres with well-designed nanostructure and enhanced photocatalytic activity. J Hazard Mater (2013) 0.78
MicroRNA-9 inhibits vasculogenic mimicry of glioma cell lines by suppressing Stathmin expression. J Neurooncol (2013) 0.78
Asymmetric construction of functionalized bicyclic imides via [3 + 2] annulation of MBH carbonates catalyzed by dipeptide-based phosphines. Org Lett (2012) 0.78
Direct asymmetric three-component organocatalytic anti-selective Mannich reactions in a purely aqueous system. Org Biomol Chem (2007) 0.78
Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: asymmetric preparation of 3-nitro-1,2-dihydroquinolines. Org Biomol Chem (2010) 0.78
Spatial and temporal expression of c-mos in mouse testis during postnatal development. Asian J Androl (2007) 0.78
Novel opioid peptide derived antagonists containing (2S)-2-methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp]. J Med Chem (2008) 0.77
[Effect of acupuncture combined behavior intervention on children with autism]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2006) 0.77
Asymmetric organocatalytic Michael addition of ketones to vinyl sulfone. Chem Commun (Camb) (2008) 0.77
Asymmetric generation of fluorine-containing quaternary carbons adjacent to tertiary stereocenters: uses of fluorinated methines as nucleophiles. Chem Commun (Camb) (2009) 0.77