Published in Bioorg Med Chem Lett on February 17, 2010
Targeted Detection of G-Quadruplexes in Cellular RNAs. Angew Chem Int Ed Engl (2015) 0.82
Mechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells. Sci Rep (2016) 0.81
Macrocyclic biphenyl tetraoxazoles: synthesis, evaluation as G-quadruplex stabilizers and cytotoxic activity. Bioorg Med Chem (2013) 0.79
Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes. Sci Rep (2016) 0.75
Macrocyclic pyridyl polyoxazoles: structure-activity studies of the aminoalkyl side-chain on G-quadruplex stabilization and cytotoxic activity. Molecules (2013) 0.75
The KEGG resource for deciphering the genome. Nucleic Acids Res (2004) 53.05
Development of a chemical structure comparison method for integrated analysis of chemical and genomic information in the metabolic pathways. J Am Chem Soc (2003) 15.30
LIGAND: database of chemical compounds and reactions in biological pathways. Nucleic Acids Res (2002) 13.61
Computational assignment of the EC numbers for genomic-scale analysis of enzymatic reactions. J Am Chem Soc (2004) 11.50
Mice genetically deficient in vasopressin V1a and V1b receptors are resistant to jet lag. Science (2013) 3.51
Identification of novel microRNA targets based on microRNA signatures in bladder cancer. Int J Cancer (2009) 3.15
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat Med (2009) 2.30
GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools update. Nucleic Acids Res (2007) 2.22
GLIDA: GPCR-ligand database for chemical genomic drug discovery. Nucleic Acids Res (2006) 2.21
Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Mol Cell Biol (2007) 1.63
Data mining of the public version of the FDA Adverse Event Reporting System. Int J Med Sci (2013) 1.56
Histamine synthesis is required for granule maturation in murine mast cells. Eur J Immunol (2013) 1.44
MicroRNA: biogenetic and functional mechanisms and involvements in cell differentiation and cancer. J Pharmacol Sci (2006) 1.33
Global correlation analysis for micro-RNA and mRNA expression profiles in human cell lines. J Hum Genet (2008) 1.23
MicroRNA-338-3p and microRNA-451 contribute to the formation of basolateral polarity in epithelial cells. Nucleic Acids Res (2009) 1.23
Analysis of multiple compound-protein interactions reveals novel bioactive molecules. Mol Syst Biol (2011) 1.19
Secreted CXCL1 is a potential mediator and marker of the tumor invasion of bladder cancer. Clin Cancer Res (2008) 1.18
Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system. PLoS One (2011) 1.17
Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA adverse event reporting system, AERS. J Exp Clin Cancer Res (2011) 1.15
A probabilistic model for mining implicit 'chemical compound-gene' relations from literature. Bioinformatics (2005) 1.11
Omeprazole- and esomeprazole-associated hypomagnesaemia: data mining of the public version of the FDA Adverse Event Reporting System. Int J Med Sci (2012) 1.11
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization. BMC Bioinformatics (2010) 1.11
Platinum agent-induced hypersensitivity reactions: data mining of the public version of the FDA adverse event reporting system, AERS. Int J Med Sci (2011) 1.10
Adverse event profiles of platinum agents: data mining of the public version of the FDA adverse event reporting system, AERS, and reproducibility of clinical observations. Int J Med Sci (2011) 1.09
Heuristics for chemical compound matching. Genome Inform (2003) 1.09
Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. Cancer Res (2010) 1.08
Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis. Proc Natl Acad Sci U S A (2005) 1.06
Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations. Int J Med Sci (2011) 1.05
Adverse event profile of tigecycline: data mining of the public version of the U.S. Food and Drug Administration adverse event reporting system. Biol Pharm Bull (2012) 1.02
Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database. Toxicology (2009) 0.97
Efficient tree-matching methods for accurate carbohydrate database queries. Genome Inform (2003) 0.97
The rare crystallographic structure of d(CGCGCG)(2): the natural spermidine molecule bound to the minor groove of left-handed Z-DNA d(CGCGCG)(2) at 10 degrees C. Biochem Biophys Res Commun (2007) 0.95
The SPR sensor detecting cytosine[bond]cytosine mismatches. J Am Chem Soc (2004) 0.92
Hole trapping at N6-cyclopropyldeoxyadenosine suggests a direct contribution of adenine bases to hole transport through DNA. J Am Chem Soc (2003) 0.90
Systems biology and systems chemistry: new directions for drug discovery. Chem Biol (2012) 0.90
Ligand binding to tandem G quadruplexes from human telomeric DNA. Chembiochem (2008) 0.88
GEM-TREND: a web tool for gene expression data mining toward relevant network discovery. BMC Genomics (2009) 0.88
Cbx2, a polycomb group gene, is required for Sry gene expression in mice. Endocrinology (2011) 0.87
Photoregulation of a peptide-RNA interaction on a gold surface. J Am Chem Soc (2007) 0.87
Prostaglandin E2 stimulates granulocyte colony-stimulating factor production via the prostanoid EP2 receptor in mouse peritoneal neutrophils. J Immunol (2005) 0.87
Exploiting small molecule binding to DNA for the detection of single-nucleotide mismatches and their base environment. Anal Chem (2007) 0.86
Toxicogenomic multigene biomarker for predicting the future onset of proximal tubular injury in rats. Toxicology (2012) 0.85
Microarray evaluation of EP4 receptor-mediated prostaglandin E2 suppression of 3T3-L1 adipocyte differentiation. Biochem Biophys Res Commun (2004) 0.85
Inhibition of DNA replication by a d(CAG) repeat binding ligand. Nucleic Acids Symp Ser (Oxf) (2006) 0.84
A survey of the FAERS database concerning the adverse event profiles of α1-adrenoreceptor blockers for lower urinary tract symptoms. Int J Med Sci (2013) 0.84
Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells. FEBS Lett (2008) 0.84
Computational chemogenomics: is it more than inductive transfer? J Comput Aided Mol Des (2014) 0.83
Site-specific binding of chelerythrine and sanguinarine to single pyrimidine bulges in hairpin DNA. Anal Bioanal Chem (2008) 0.83
Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface. Nucleic Acids Res (2004) 0.83
Aspirin- and clopidogrel-associated bleeding complications: data mining of the public version of the FDA adverse event reporting system, AERS. Int J Med Sci (2012) 0.83
Ligand-assisted complex formation of two DNA hairpin loops. Angew Chem Int Ed Engl (2011) 0.82
Polyamines stabilize left-handed Z-DNA: using X-ray crystallographic analysis, we have found a new type of polyamine (PA) that stabilizes left-handed Z-DNA. Biochem Biophys Res Commun (2007) 0.82
Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenesis. Toxicol Lett (2006) 0.82
Fluorescent indicator displacement assay for ligand-RNA interactions. J Am Chem Soc (2010) 0.82
Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: targeting secondary structures of pre-miRNA by small molecules. Bioorg Med Chem Lett (2012) 0.81
Allele specific C-bulge probes with one unique fluorescent molecule discriminate the single nucleotide polymorphism in DNA. Chemistry (2007) 0.81
Mismatch-binding ligands function as a molecular glue for DNA. Angew Chem Int Ed Engl (2006) 0.81
Electroconvulsive seizure-induced changes in gene expression in the mouse hypothalamic paraventricular nucleus. J Psychopharmacol (2013) 0.81
Photoswitchable molecular glue for DNA. J Am Chem Soc (2007) 0.81
Chemically induced hairpin formation in DNA monolayers. J Am Chem Soc (2002) 0.81
Characterization of gene expression profiles for different types of mast cells pooled from mouse stomach subregions by an RNA amplification method. BMC Genomics (2009) 0.81
Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads. Endocrinology (2010) 0.80
Dissecting kinase profiling data to predict activity and understand cross-reactivity of kinase inhibitors. J Chem Inf Model (2012) 0.80
Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway. J Biol Chem (2011) 0.80
A synthetic riboswitch that operates using a rationally designed ligand-RNA pair. Angew Chem Int Ed Engl (2013) 0.80
Binding of naphthyridine carbamate dimer to the (CGG)n repeat results in the disruption of the G-C base pairing. Angew Chem Int Ed Engl (2005) 0.80
Formation and destruction of the guanine quartet in solution observed by cold-spray ionization mass spectrometry. Chem Commun (Camb) (2003) 0.80
Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling. Biochimie (2010) 0.80
Electroconvulsive seizures activate anorexigenic signals in the ventromedial nuclei of the hypothalamus. Neuropharmacology (2013) 0.79
Ligand inducible assembly of a DNA tetrahedron. Chem Commun (Camb) (2011) 0.79
Laplacian linear discriminant analysis approach to unsupervised feature selection. IEEE/ACM Trans Comput Biol Bioinform (2009) 0.79
A small molecule regulates hairpin structures in d(CGG) trinucleotide repeats. Bioorg Med Chem Lett (2012) 0.79
Correlation index-based responsible-enzyme gene screening (CIRES), a novel DNA microarray-based method for enzyme gene involved in glycan biosynthesis. PLoS One (2007) 0.79
Secondary-structure-inducible ligand fluorescence coupled with PCR. Angew Chem Int Ed Engl (2009) 0.79
Application of a new probabilistic model for mining implicit associated cancer genes from OMIM and medline. Cancer Inform (2007) 0.79
Application of L-DNA as a molecular tag. Nucleic Acids Symp Ser (Oxf) (2005) 0.79
Antisense-induced guanine quadruplexes inhibit reverse transcription by HIV-1 reverse transcriptase. J Am Chem Soc (2010) 0.79
Cross-target view to feature selection: identification of molecular interaction features in ligand-target space. J Chem Inf Model (2010) 0.79
Substructure mining of GPCR ligands reveals activity-class specific functional groups in an unbiased manner. J Chem Inf Model (2009) 0.79
The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA. Bioorg Med Chem (2009) 0.79
Guanine of the third strand of C.G*G triplex serves as an effective hole trap. J Am Chem Soc (2002) 0.78
A hierarchical mixture of Markov models for finding biologically active metabolic paths using gene expression and protein classes. Proc IEEE Comput Syst Bioinform Conf (2004) 0.78
A small molecule affecting the replication of trinucleotide repeat d(GAA)n. Chemistry (2009) 0.78
A novel DANP-coupled hairpin RT-PCR for rapid detection of Chikungunya virus. J Mol Diagn (2013) 0.77
Synthesis and reaction of DNA oligomers containing modified cytosines related to bisulfite sequencing. Org Lett (2009) 0.77
Control of DNA hybridization by photoswitchable molecular glue. Chem Soc Rev (2011) 0.77
Molecular-glue-triggered DNA assembly to form a robust and photoresponsive nano-network. Chemistry (2011) 0.77
NMR structural analysis of the G.G mismatch DNA complexed with naphthyridine-dimer. Nucleic Acids Symp Ser (Oxf) (2005) 0.77
2-Ureidoquinoline: a useful molecular element for stabilizing single cytosine and thymine bulges. Bioorg Med Chem Lett (2004) 0.77
Genotyping by allele-specific L-DNA-tagged PCR. J Biotechnol (2008) 0.77
Augmentation of drug-induced cell death by ER protein BRI3BP. Biochem Biophys Res Commun (2007) 0.77
N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA. Bioorg Med Chem (2005) 0.77
Programmed assembly of organic radicals on DNA. Chem Commun (Camb) (2010) 0.77
A light-driven supramolecular optical switch. Angew Chem Int Ed Engl (2009) 0.77
Cholinesterase inhibitors and Pisa syndrome: a pharmacovigilance study. Pharmacotherapy (2013) 0.76
A new ligand binding to G-G mismatch having improved thermal and alkaline stability. Bioorg Med Chem Lett (2005) 0.76