Published in Cancer Treat Res on January 01, 2009
Observational Study in Localized Osteosarcoma (ISG Os2Oss) | NCT04890067
miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res (2012) 2.52
Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Rep (2014) 2.27
The molecular pathogenesis of osteosarcoma: a review. Sarcoma (2011) 1.91
Survival from high-grade localised extremity osteosarcoma: combined results and prognostic factors from three European Osteosarcoma Intergroup randomised controlled trials. Ann Oncol (2011) 1.28
Programmed cell death ligand 1 expression in osteosarcoma. Cancer Immunol Res (2014) 1.23
MiR-133b is down-regulated in human osteosarcoma and inhibits osteosarcoma cells proliferation, migration and invasion, and promotes apoptosis. PLoS One (2013) 1.15
MicroRNA function and dysregulation in bone tumors: the evidence to date. Cancer Manag Res (2014) 1.07
Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy. Pharmacogenomics J (2011) 1.05
Descriptive epidemiology of malignant primary osteosarcoma using population-based registries, United States, 1999-2008. J Registry Manag (2013) 1.04
miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells. Oncotarget (2015) 1.00
Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma. PLoS One (2012) 0.99
NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene (2015) 0.99
What are the levels of evidence on which we base decisions for surgical management of lower extremity bone tumors? Clin Orthop Relat Res (2013) 0.98
Perspectives on cancer stem cells in osteosarcoma. Cancer Lett (2012) 0.97
Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity. Oncotarget (2013) 0.97
Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy. Pak J Med Sci (2013) 0.96
MicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcoma. Onco Targets Ther (2013) 0.95
Surgical technique: Computer-generated custom jigs improve accuracy of wide resection of bone tumors. Clin Orthop Relat Res (2013) 0.95
The tumor suppressor role of miR-124 in osteosarcoma. PLoS One (2014) 0.95
Similar survival but better function for patients after limb salvage versus amputation for distal tibia osteosarcoma. Clin Orthop Relat Res (2012) 0.95
Endothelin-1 promotes osteosarcoma cell invasion and survival against cisplatin-induced apoptosis. Clin Orthop Relat Res (2011) 0.94
CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma. Sci Rep (2015) 0.91
Dendropanoxide induces autophagy through ERK1/2 activation in MG-63 human osteosarcoma cells and autophagy inhibition enhances dendropanoxide-induced apoptosis. PLoS One (2013) 0.89
P2X7 Receptor Function in Bone-Related Cancer. J Osteoporos (2012) 0.89
The epidemiology of bone cancer in 0 - 39 year olds in northern England, 1981 - 2002. BMC Cancer (2010) 0.89
Understanding the Biology of Bone Sarcoma from Early Initiating Events through Late Events in Metastasis and Disease Progression. Front Oncol (2013) 0.88
Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma. Sci Rep (2016) 0.88
Silencing of Barkor/ATG14 sensitizes osteosarcoma cells to cisplatin‑induced apoptosis. Int J Mol Med (2013) 0.88
Moving forward through consensus: protocol for a modified Delphi approach to determine the top research priorities in the field of orthopaedic oncology. BMJ Open (2016) 0.87
GRM4 gene polymorphism is associated with susceptibility and prognosis of osteosarcoma in a Chinese Han population. Med Oncol (2014) 0.86
Decreased expression of long non-coding RNA MEG3 acts as a potential predictor biomarker in progression and poor prognosis of osteosarcoma. Int J Clin Exp Pathol (2015) 0.86
S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications. Cancer Med (2015) 0.86
In silico functional analyses and discovery of survival-associated microRNA signatures in pediatric osteosarcoma. Oncoscience (2014) 0.86
What Sport Activity Levels Are Achieved in Patients After Resection and Endoprosthetic Reconstruction for a Proximal Femur Bone Sarcoma? Clin Orthop Relat Res (2016) 0.86
Sociooccupational and physical outcomes more than 20 years after the diagnosis of osteosarcoma in children and adolescents: limb salvage versus amputation. Cancer (2013) 0.86
RNAi-mediated silencing of AQP1 expression inhibited the proliferation, invasion and tumorigenesis of osteosarcoma cells. Cancer Biol Ther (2015) 0.86
CD133 expression predicts lung metastasis and poor prognosis in osteosarcoma patients: A clinical and experimental study. Exp Ther Med (2012) 0.86
Inhibition of beclin1 affects the chemotherapeutic sensitivity of osteosarcoma. Int J Clin Exp Pathol (2014) 0.86
miR-155 mediates drug resistance in osteosarcoma cells via inducing autophagy. Exp Ther Med (2014) 0.85
Extensor function after medial gastrocnemius flap reconstruction of the proximal tibia. Clin Orthop Relat Res (2013) 0.85
Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases. Oncotarget (2015) 0.84
Small-area analyses of bone cancer diagnosed in Great Britain provide clues to aetiology. BMC Cancer (2012) 0.84
Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines. Genome Med (2012) 0.84
TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin. Oncol Lett (2013) 0.84
Combined microRNA-340 and ROCK1 mRNA profiling predicts tumor progression and prognosis in pediatric osteosarcoma. Int J Mol Sci (2014) 0.84
The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis. J Cancer Res Clin Oncol (2011) 0.84
Associations of IL-27 polymorphisms and serum IL-27p28 levels with osteosarcoma risk. Medicine (Baltimore) (2014) 0.84
Effects of the myeloid cell nuclear differentiation antigen on the proliferation, apoptosis and migration of osteosarcoma cells. Oncol Lett (2014) 0.83
MicroRNA-138 functions as a tumor suppressor in osteosarcoma by targeting differentiated embryonic chondrocyte gene 2. J Exp Clin Cancer Res (2016) 0.83
Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma. Oncotarget (2016) 0.82
Comparison of pirarubicin-based versus gemcitabine-docetaxel chemotherapy for relapsed and refractory osteosarcoma: a single institution experience. Int J Clin Oncol (2012) 0.82
Interferon-α suppresses invasion and enhances cisplatin-mediated apoptosis and autophagy in human osteosarcoma cells. Oncol Lett (2013) 0.82
A polymorphism site in the pre‑miR‑34a coding region reduces miR‑34a expression and promotes osteosarcoma cell proliferation and migration. Mol Med Rep (2014) 0.82
Stereotactic radiosurgery, a potential alternative treatment for pulmonary metastases from osteosarcoma. Int J Oncol (2014) 0.82
Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo. Cell Death Dis (2016) 0.81
Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways. Oncotarget (2016) 0.81
Polymorphisms of vascular endothelial growth factor on prognosis in osteosarcoma patients. Pak J Med Sci (2014) 0.81
FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma. Int J Mol Sci (2015) 0.81
Low miR-34a and miR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma. Am J Transl Res (2015) 0.81
Astrocyte elevated gene-1 regulates osteosarcoma cell invasion and chemoresistance via endothelin-1/endothelin A receptor signaling. Oncol Lett (2012) 0.81
Forkhead box protein M1 predicts outcome in human osteosarcoma. Int J Clin Exp Med (2015) 0.81
MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells. Int J Oncol (2014) 0.81
miR-155 inhibitor reduces the proliferation and migration in osteosarcoma MG-63 cells. Exp Ther Med (2014) 0.80
miR-181c associates with tumor relapse of high grade osteosarcoma. Oncotarget (2015) 0.80
Haptic robot-assisted surgery improves accuracy of wide resection of bone tumors: a pilot study. Clin Orthop Relat Res (2013) 0.80
Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature. J Oral Maxillofac Pathol (2014) 0.80
Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells. Int J Oncol (2015) 0.80
Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis. Pediatr Blood Cancer (2014) 0.80
Bone formation induced by BMP-2 in human osteosarcoma cells. Int J Oncol (2013) 0.80
High-dose chemotherapy and autologous stem cell transplantation with melphalan, etoposide and carboplatin for high-risk osteosarcoma. Bone Marrow Transplant (2015) 0.79
Gene expression profiling analysis of osteosarcoma cell lines. Mol Med Rep (2015) 0.79
Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells. PLoS One (2014) 0.79
New small molecules targeting apoptosis and cell viability in osteosarcoma. PLoS One (2015) 0.79
Clinical significance of hypoxia-inducible factor 1 and VEGF-A in osteosarcoma. Int J Clin Oncol (2015) 0.79
WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma. Cancer Res (2016) 0.79
Moving Forward Through Consensus: A Modified Delphi Approach to Determine the Top Research Priorities in Orthopaedic Oncology. Clin Orthop Relat Res (2017) 0.79
Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty. Exp Ther Med (2014) 0.78
Elevated ASCL2 expression is associated with metastasis of osteosarcoma and predicts poor prognosis of the patients. Am J Cancer Res (2016) 0.78
Upregulation of lncRNA HNF1A-AS1 promotes cell proliferation and metastasis in osteosarcoma through activation of the Wnt/β-catenin signaling pathway. Am J Transl Res (2016) 0.78
Is fluoride a risk factor for bone cancer? Small area analysis of osteosarcoma and Ewing sarcoma diagnosed among 0-49-year-olds in Great Britain, 1980-2005. Int J Epidemiol (2014) 0.78
MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression. Mol Med Rep (2015) 0.78
Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma. PLoS One (2014) 0.78
Effect of ABCB1 polymorphism on the clinical outcome of osteosarcoma patients after receiving chemotherapy. Pak J Med Sci (2014) 0.78
HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis. J Cancer Res Clin Oncol (2012) 0.78
Genetic polymorphisms in nucleotide excision repair pathway influences response to chemotherapy and overall survival in osteosarcoma. Int J Clin Exp Pathol (2015) 0.78
Correlations of ezrin expression with pathological characteristics and prognosis of osteosarcoma: a meta-analysis. ScientificWorldJournal (2014) 0.78
Osteotropic cancer diagnosis by an osteocalcin inspired molecular imaging mimetic. Biochim Biophys Acta (2013) 0.78
Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population. Int J Clin Exp Pathol (2015) 0.78
Crosstalk between Beclin-1-dependent autophagy and caspase‑dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells. Oncol Rep (2016) 0.78
Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG‑63 through the ROS/JNK signaling pathway. Oncol Rep (2016) 0.78
Genetic polymorphisms of interleukin-1 beta and osteosarcoma risk. Int Orthop (2014) 0.78
Prophylactic antibiotic regimens in tumour surgery (PARITY): a pilot multicentre randomised controlled trial. Bone Joint Res (2015) 0.78
Cobalt chloride inhibits tumor formation in osteosarcoma cells through upregulation of HIF-1α Oncol Lett (2013) 0.78
Down-regulation of S100A9 inhibits osteosarcoma cell growth through inactivating MAPK and NF-κB signaling pathways. BMC Cancer (2016) 0.78
Auranofin is a potent suppressor of osteosarcoma metastasis. Oncotarget (2016) 0.78
Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression. Oncotarget (2016) 0.78
MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells. PLoS One (2016) 0.78
miR-200bc/429 Inhibits Osteosarcoma Cell Proliferation and Invasion by Targeting PMP22. Med Sci Monit (2017) 0.77
Overexpression of miR-664 is associated with enhanced osteosarcoma cell migration and invasion ability via targeting SOX7. Clin Exp Med (2015) 0.77
Cisplatin promotes mesenchymal-like characteristics in osteosarcoma through Snail. Oncol Lett (2016) 0.77
Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma. J Pediatr Surg (2006) 1.50
The etiology of osteosarcoma. Cancer Treat Res (2009) 1.39
Psychosocial and functional outcomes in long-term survivors of osteosarcoma: a comparison of limb-salvage surgery and amputation. Pediatr Blood Cancer (2010) 1.24
Chemotherapy response is an important predictor of local recurrence in Ewing sarcoma. Cancer (2007) 1.21
Functional, psychosocial and professional outcomes in long-term survivors of lower-extremity osteosarcomas: amputation versus limb salvage. Cancer Treat Res (2009) 1.08
Ewing's sarcoma of the mobile spine. Spine (Phila Pa 1976) (2005) 1.01
Osteosarcoma multidisciplinary approach to the management from the pathologist's perspective. Cancer Treat Res (2009) 0.92
Sociooccupational and physical outcomes more than 20 years after the diagnosis of osteosarcoma in children and adolescents: limb salvage versus amputation. Cancer (2013) 0.86
High-dose ifosfamide in relapsed pediatric osteosarcoma: therapeutic effects and renal toxicity. Pediatr Blood Cancer (2005) 0.81
Clinical and pathologic study of two siblings with osteosarcoma. Med Pediatr Oncol (2002) 0.79
Comparison of doxorubicin cardiotoxicity in pediatric sarcoma patients when given with dexrazoxane versus as continuous infusion. Pediatr Hematol Oncol (2010) 0.78
Adult survivors of childhood cancer and unemployment: a metaanalysis. Cancer (2006) 0.78
Methylene blue reversal of ifosfamide-related encephalopathy. J Pediatr Hematol Oncol (2004) 0.77
The classic: recent advances in chemotherapy of metastatic osteogenic sarcoma. 1972. Clin Orthop Relat Res (2005) 0.77
Osteosarcoma: lessons learned and future avenues. Sarcoma (2013) 0.76
Editorial summation. What have we learned, where do we stand and where do we go from here? Cancer Treat Res (2009) 0.76
Metachronous skeletal osteosarcoma after therapy. J Clin Oncol (2004) 0.75
Eosinophilic pneumonia in an infant. Med Pediatr Oncol (2002) 0.75
Relapse eighteen and one-half years after apparent cure of sarcoma botryoides of the vagina. Med Pediatr Oncol (2003) 0.75
Conditions that mimic osteosarcoma. Cancer Treat Res (2009) 0.75