PubRank

Chenglong Li

Author PubWeight™ 88.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia. Cancer Cell 2010 2.37
2 Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells. Cancer Res 2010 1.91
3 Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. Proc Natl Acad Sci U S A 2006 1.88
4 A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Neoplasia 2010 1.70
5 STAT3 is necessary for proliferation and survival in colon cancer-initiating cells. Cancer Res 2011 1.63
6 Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning 1H NMR spectroscopy in conjunction with multivariate data analysis. J Proteome Res 2007 1.47
7 Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease. Circulation 2012 1.31
8 Curcumin is a potent DNA hypomethylation agent. Bioorg Med Chem Lett 2008 1.31
9 Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells. J Biol Chem 2010 1.28
10 The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer 2010 1.27
11 JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells. Cancer Res 2013 1.19
12 Design, synthesis, and studies of small molecule STAT3 inhibitors. Bioorg Med Chem Lett 2007 1.18
13 Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J Biol Chem 2003 1.14
14 ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB. Cell Rep 2013 1.14
15 STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH⁺/CD133⁺ stem cell-like human colon cancer cells. Biochem Biophys Res Commun 2011 1.13
16 Epigenetic silencing of miR-338-3p contributes to tumorigenicity in gastric cancer by targeting SSX2IP. PLoS One 2013 1.11
17 Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex. Clin Cancer Res 2012 1.11
18 Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer. J Gastroenterol 2013 1.09
19 LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3. J Biol Chem 2005 1.09
20 A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. Mol Cancer 2010 1.05
21 Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK. FEBS Lett 2012 1.05
22 Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid. Biochemistry 2003 1.05
23 Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors. J Pharmacol Exp Ther 2010 1.03
24 Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice. Invest New Drugs 2011 1.03
25 The serine-rich domain from Crk-associated substrate (p130cas) is a four-helix bundle. J Biol Chem 2005 1.03
26 alpha-Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 function. J Biol Chem 2006 1.03
27 New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells. Cancer Sci 2009 1.01
28 Celecoxib inhibits interleukin-6/interleukin-6 receptor-induced JAK2/STAT3 phosphorylation in human hepatocellular carcinoma cells. Cancer Prev Res (Phila) 2011 1.01
29 New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells. BMC Cancer 2009 1.00
30 Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma. Cancer Res 2014 1.00
31 Modulation of DNA methylation by a sesquiterpene lactone parthenolide. J Pharmacol Exp Ther 2009 0.99
32 Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12. PLoS One 2012 0.99
33 Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. J Pharmacol Exp Ther 2008 0.98
34 Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue. J Biol Chem 2010 0.98
35 Structure-activity relationship studies of curcumin analogues. Bioorg Med Chem Lett 2009 0.97
36 The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells. PLoS One 2011 0.96
37 Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. J Med Chem 2010 0.96
38 Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines. PLoS One 2012 0.95
39 IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells. Cell Cycle 2010 0.94
40 The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC Cancer 2011 0.93
41 Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design. J Med Chem 2013 0.93
42 Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells. Int J Oncol 2011 0.92
43 Drug design targeting protein-protein interactions (PPIs) using multiple ligand simultaneous docking (MLSD) and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface. J Med Chem 2014 0.91
44 A thalidomide analogue with in vitro antiproliferative, antimitotic, and microtubule-stabilizing activities. Mol Cancer Ther 2006 0.91
45 A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells. Int J Cancer 2011 0.90
46 Multiple ligand simultaneous docking: orchestrated dancing of ligands in binding sites of protein. J Comput Chem 2010 0.90
47 Decrease of miR-202-3p expression, a novel tumor suppressor, in gastric cancer. PLoS One 2013 0.90
48 Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells. Cancer Sci 2011 0.90
49 Identification of a negative allosteric site on human α4β2 and α3β4 neuronal nicotinic acetylcholine receptors. PLoS One 2011 0.89
50 XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis 2011 0.88
51 Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells. Anticancer Drugs 2009 0.88
52 Conformational restrictions in the active site of unliganded human caspase-3. J Mol Recognit 2003 0.87
53 Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening. J Biol Chem 2004 0.87
54 Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95. J Biol Chem 2011 0.86
55 Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation. PLoS One 2013 0.86
56 LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells. Anticancer Res 2011 0.86
57 Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance. J Med Chem 2006 0.86
58 Carborane clusters in computational drug design: a comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex. J Chem Inf Model 2009 0.85
59 Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells. Biochem Biophys Res Commun 2011 0.85
60 Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416. Bioorg Med Chem 2006 0.85
61 Fragment-based drug design and drug repositioning using multiple ligand simultaneous docking (MLSD): identifying celecoxib and template compounds as novel inhibitors of signal transducer and activator of transcription 3 (STAT3). J Med Chem 2011 0.85
62 STAT3 as a Therapeutic Target for Glioblastoma. Anticancer Agents Med Chem 2010 0.85
63 Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents. Bioorg Med Chem 2007 0.85
64 Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). J Biol Chem 2002 0.85
65 Novel inhibitor discovery through virtual screening against multiple protein conformations generated via ligand-directed modeling: a maternal embryonic leucine zipper kinase example. J Chem Inf Model 2012 0.84
66 XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells. PLoS One 2012 0.84
67 Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction. ACS Chem Biol 2012 0.84
68 Development and application of a quantitative fluorescence-based immunochromatographic assay for fumonisin b1 in maize. J Agric Food Chem 2014 0.84
69 Characterization of molecular recognition of STAT3 SH2 domain inhibitors through molecular simulation. J Mol Recognit 2011 0.83
70 Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. J Biol Chem 2007 0.83
71 Analysis of efficacy of chiral adrenergic agonists. Chirality 2008 0.82
72 Thermally responsive nanoparticle-encapsulated curcumin and its combination with mild hyperthermia for enhanced cancer cell destruction. Acta Biomater 2014 0.81
73 Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors. J Med Chem 2011 0.81
74 Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry 2011 0.81
75 Dynamic ligand-induced-fit simulation via enhanced conformational samplings and ensemble dockings: a survivin example. J Phys Chem B 2010 0.80
76 Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. J Nat Prod 2013 0.80
77 Sphenostylisins A-K: bioactive modified isoflavonoid constituents of the root bark of Sphenostylis marginata ssp. erecta. J Org Chem 2013 0.79
78 Persistent GP130/STAT3 Signaling Contributes to the Resistance of Doxorubicin, Cisplatin, and MEK Inhibitor in Human Rhabdomyosarcoma Cells. Curr Cancer Drug Targets 2016 0.79
79 Computational structure activity relationship studies on the CD1d/glycolipid/TCR complex using AMBER and AUTODOCK. J Chem Inf Model 2009 0.78
80 Structurally adaptive hot spots at a protein interaction interface on TRAF3. J Mol Recognit 2002 0.78
81 Comparative docking assessment of glucokinase interactions with its allosteric activators. Curr Chem Genomics 2008 0.78
82 Insights into the binding mode of curcumin to MD-2: studies from molecular docking, molecular dynamics simulations and experimental assessments. Mol Biosyst 2015 0.77
83 Effect of architecture on the micellar properties of poly (ɛ-caprolactone) containing sulfobetaines. Colloids Surf B Biointerfaces 2013 0.77
84 Defining the putative inhibitory site for a selective negative allosteric modulator of human α4β2 neuronal nicotinic receptors. ACS Chem Neurosci 2012 0.77
85 Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle. Bioorg Med Chem Lett 2013 0.77
86 Comparative study of different procedures for the separation of peripheral blood mononuclear cells in cytokine-induced killer cell immunotherapy for hepatocarcinoma. Tumour Biol 2014 0.77
87 Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas. Blood 2012 0.76
88 Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies. Bioorg Med Chem 2013 0.76
89 O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2. Anticancer Agents Med Chem 2016 0.76
90 MicroRNA-183 Functions As an Oncogene by Regulating PDCD4 in Gastric Cancer. Anticancer Agents Med Chem 2016 0.75
91 4-Nitro-phenyl N-(2-sulfamoylphen-yl)carbamate. Acta Crystallogr Sect E Struct Rep Online 2013 0.75
92 8,8-dialkyldihydroberberines with potent antiprotozoal activity. J Nat Prod 2012 0.75
93 Correction: PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. J Immunol 2017 0.75
94 Visual Tracking via Dynamic Graph Learning. IEEE Trans Pattern Anal Mach Intell 2018 0.75
95 Learning Collaborative Sparse Representation for Grayscale-Thermal Tracking. IEEE Trans Image Process 2016 0.75
96 A highly selective fluorescent sensor for Al³⁺ and the use of the resulting complex as a secondary sensor for PPi in aqueous media: its applicability in live cell imaging. Dalton Trans 2015 0.75
97 PISA: pixelwise image saliency by aggregating complementary appearance contrast measures with edge-preserving coherence. IEEE Trans Image Process 2015 0.75
98 Detection-Free Multiobject Tracking by Reconfigurable Inference With Bundle Representations. IEEE Trans Cybern 2015 0.75
99 Laser frequency locking with second-harmonic demodulation. Appl Opt 2014 0.75
100 An Approach to Streaming Video Segmentation With Sub-Optimal Low-Rank Decomposition. IEEE Trans Image Process 2016 0.75
101 Influence of Small Molecular Property on Antibody Response. J Agric Food Chem 2020 0.75