| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis.
|
Clin Cancer Res
|
2002
|
2.55
|
|
2
|
Anticancer potential of silymarin: from bench to bed side.
|
Anticancer Res
|
2007
|
1.91
|
|
3
|
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
|
Oncogene
|
2003
|
1.58
|
|
4
|
Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
|
Cancer Biol Ther
|
2003
|
1.46
|
|
5
|
Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice.
|
Cancer Res
|
2007
|
1.46
|
|
6
|
Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells.
|
Clin Cancer Res
|
2006
|
1.46
|
|
7
|
Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
|
Cancer Res
|
2007
|
1.45
|
|
8
|
Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells.
|
Acta Oncol
|
2009
|
1.43
|
|
9
|
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
|
Carcinogenesis
|
2005
|
1.37
|
|
10
|
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.
|
Cancer Res
|
2008
|
1.29
|
|
11
|
Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
|
Cancer Res
|
2007
|
1.22
|
|
12
|
Genetically engineered bacteria: an emerging tool for environmental remediation and future research perspectives.
|
Gene
|
2011
|
1.19
|
|
13
|
Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release.
|
Carcinogenesis
|
2002
|
1.15
|
|
14
|
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
|
Cancer Res
|
2004
|
1.15
|
|
15
|
Tumor angiogenesis--a potential target in cancer chemoprevention.
|
Food Chem Toxicol
|
2007
|
1.14
|
|
16
|
Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
|
Carcinogenesis
|
2006
|
1.13
|
|
17
|
Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
|
Neoplasia
|
2010
|
1.12
|
|
18
|
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
|
Cancer Res
|
2010
|
1.10
|
|
19
|
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
|
Cancer Prev Res (Phila)
|
2008
|
1.09
|
|
20
|
Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.
|
Int J Cancer
|
2008
|
1.07
|
|
21
|
A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
|
Cancer Res
|
2005
|
1.07
|
|
22
|
Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin.
|
Carcinogenesis
|
2005
|
1.05
|
|
23
|
Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells.
|
Breast Cancer Res Treat
|
2004
|
1.05
|
|
24
|
p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
|
Cancer Res
|
2009
|
1.04
|
|
25
|
Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice.
|
Neoplasia
|
2010
|
1.04
|
|
26
|
Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
|
Carcinogenesis
|
2004
|
1.03
|
|
27
|
Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy.
|
Mutat Res
|
2011
|
1.02
|
|
28
|
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
|
Mol Cancer Ther
|
2007
|
1.02
|
|
29
|
Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.
|
Mol Carcinog
|
2011
|
1.02
|
|
30
|
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
|
Mol Cancer Ther
|
2008
|
1.02
|
|
31
|
Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
|
Cancer Prev Res (Phila)
|
2009
|
1.02
|
|
32
|
Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice.
|
Clin Cancer Res
|
2008
|
1.02
|
|
33
|
Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
|
Mol Carcinog
|
2010
|
1.01
|
|
34
|
Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype.
|
Cell Cycle
|
2008
|
1.01
|
|
35
|
Silibinin efficacy against human hepatocellular carcinoma.
|
Clin Cancer Res
|
2005
|
1.00
|
|
36
|
Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.
|
Clin Cancer Res
|
2010
|
1.00
|
|
37
|
Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.
|
J Biol Chem
|
2005
|
1.00
|
|
38
|
Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells.
|
Anticancer Res
|
2003
|
1.00
|
|
39
|
Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators.
|
Mol Carcinog
|
2010
|
0.99
|
|
40
|
Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
|
Clin Cancer Res
|
2010
|
0.99
|
|
41
|
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
0.99
|
|
42
|
Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes.
|
Carcinogenesis
|
2003
|
0.97
|
|
43
|
Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells.
|
Neoplasia
|
2004
|
0.95
|
|
44
|
Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release.
|
Carcinogenesis
|
2004
|
0.93
|
|
45
|
Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.
|
Mol Carcinog
|
2011
|
0.93
|
|
46
|
Silibinin suppresses spontaneous tumorigenesis in APC min/+ mouse model by modulating beta-catenin pathway.
|
Pharm Res
|
2009
|
0.92
|
|
47
|
Anti-angiogenic efficacy of grape seed extract in endothelial cells.
|
Oncol Rep
|
2004
|
0.92
|
|
48
|
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
|
Carcinogenesis
|
2006
|
0.91
|
|
49
|
Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention.
|
Carcinogenesis
|
2011
|
0.88
|
|
50
|
Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells.
|
Biochem Biophys Res Commun
|
2003
|
0.86
|
|
51
|
Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
|
Anticancer Res
|
2003
|
0.85
|
|
52
|
Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression.
|
Cancer Prev Res (Phila)
|
2013
|
0.85
|
|
53
|
Agrobacterium tumefaciens mediated transfer of Phaseolus vulgaris alpha-amylase inhibitor-1 gene into mungbean Vigna radiata (L.) Wilczek using bar as selectable marker.
|
Plant Cell Rep
|
2006
|
0.85
|
|
54
|
Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
|
Mol Cancer Ther
|
2006
|
0.84
|
|
55
|
Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells.
|
Biochem Biophys Res Commun
|
2004
|
0.83
|
|
56
|
Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells.
|
Nutr Cancer
|
2013
|
0.82
|
|
57
|
Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells.
|
Int J Oncol
|
2003
|
0.81
|
|
58
|
Advances in prostate cancer chemoprevention: a translational perspective.
|
Nutr Cancer
|
2013
|
0.81
|
|
59
|
Differential toxicity of cadmium to mustard (Brassica juncia L.) genotypes under higher metal levels.
|
J Environ Biol
|
2011
|
0.79
|
|
60
|
Cadmium tolerance and its phytoremediation by two oil yielding plants Ricinus communis (L.) and Brassica juncea (L.) from the contaminated soil.
|
Int J Phytoremediation
|
2012
|
0.79
|
|
61
|
Arsenic and its combinations in cancer therapeutics.
|
Ther Deliv
|
2011
|
0.78
|
|
62
|
Inhibition of angiogenic attributes by decursin in endothelial cells and ex vivo rat aortic ring angiogenesis model.
|
Indian J Exp Biol
|
2011
|
0.78
|
|
63
|
Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor.
|
Nutr Cancer
|
2005
|
0.78
|
|
64
|
Silibinin combination with arsenic strongly inhibits survival and invasiveness of human prostate carcinoma cells.
|
Nutr Cancer
|
2015
|
0.77
|
|
65
|
Proceedings of the Indo-U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survival.
|
Cancer Med
|
2013
|
0.76
|
|
66
|
Remediation of nitrite contamination in ground and surface waters using aquatic macrophytes.
|
J Environ Biol
|
2012
|
0.76
|
|
67
|
Growth, biomass production and remediation of copper contamination by Jatropha curcas plant in industrial wasteland soil.
|
J Environ Biol
|
2012
|
0.75
|
|
68
|
Growth, tolerance efficiency and phytoremediation potential of Ricinus communis (L.) and Brassica juncea (L.) in salinity and drought affected cadmium contaminated soil.
|
Ecotoxicol Environ Saf
|
2012
|
0.75
|
|
69
|
Conservation tillage, optimal water and organic nutrient supply enhance soil microbial activities during wheat (Triticum Aestivum L.) cultivation.
|
Braz J Microbiol
|
2011
|
0.75
|
|
70
|
Improving soil microbiology under rice-wheat crop rotation in Indo-Gangetic Plains by optimized resource management.
|
Environ Monit Assess
|
2015
|
0.75
|
|
71
|
Ricinus communis L. A Value Added Crop for Remediation of Cadmium Contaminated Soil.
|
Bull Environ Contam Toxicol
|
2016
|
0.75
|
|
72
|
Degradation of lindane contaminated soil using zero-valent iron nanoparticles.
|
J Biomed Nanotechnol
|
2011
|
0.75
|
|
73
|
Organic matrix based slow release fertilizer enhances plant growth, nitrate assimilation and seed yield of Indian mustard (Brassica juncea L.).
|
J Environ Biol
|
2011
|
0.75
|
|
74
|
Increase in growth, productivity and nutritional status of wheat (Triticum aestivum L. cv. WH-711) and enrichment in soil fertility applied with organic matrix entrapped urea.
|
J Environ Biol
|
2013
|
0.75
|