1
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Transcriptional regulatory networks in Saccharomyces cerevisiae.
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Science
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2002
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43.52
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2
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STEM: a tool for the analysis of short time series gene expression data.
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BMC Bioinformatics
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2006
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5.21
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3
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A critical assessment of Mus musculus gene function prediction using integrated genomic evidence.
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Genome Biol
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2008
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4.78
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4
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The sirtuin SIRT6 regulates lifespan in male mice.
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Nature
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2012
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4.07
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5
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Evaluation of different biological data and computational classification methods for use in protein interaction prediction.
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Proteins
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2006
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3.78
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6
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Clustering short time series gene expression data.
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Bioinformatics
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2005
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3.48
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7
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Reconstructing dynamic regulatory maps.
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Mol Syst Biol
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2007
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2.36
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8
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Random forest similarity for protein-protein interaction prediction from multiple sources.
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Pac Symp Biocomput
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2005
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2.25
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9
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A probabilistic generative model for GO enrichment analysis.
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Nucleic Acids Res
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2008
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2.01
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10
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Integrating multiple evidence sources to predict transcription factor binding in the human genome.
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Genome Res
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2010
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1.84
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11
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Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways.
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Am J Respir Crit Care Med
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2014
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1.69
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12
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Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis.
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Elife
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2013
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1.64
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13
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A biological solution to a fundamental distributed computing problem.
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Science
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2011
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1.62
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14
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Impact of the solvent capacity constraint on E. coli metabolism.
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BMC Syst Biol
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2008
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1.61
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15
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Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
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Am J Respir Crit Care Med
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2014
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1.54
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16
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Cross species analysis of microarray expression data.
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Bioinformatics
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2009
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1.47
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17
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A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli.
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PLoS Comput Biol
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2008
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1.40
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18
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Discovering pathways by orienting edges in protein interaction networks.
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Nucleic Acids Res
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2010
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1.32
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19
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Protein complex identification by supervised graph local clustering.
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Bioinformatics
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2008
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1.32
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20
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Backup in gene regulatory networks explains differences between binding and knockout results.
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Mol Syst Biol
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2009
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1.27
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21
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A mixture of feature experts approach for protein-protein interaction prediction.
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BMC Bioinformatics
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2007
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1.24
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22
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Alignment and classification of time series gene expression in clinical studies.
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Bioinformatics
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2008
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1.22
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23
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Biological interaction networks are conserved at the module level.
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BMC Syst Biol
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2011
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1.16
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24
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Extracting dynamics from static cancer expression data.
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IEEE/ACM Trans Comput Biol Bioinform
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2008
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1.14
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25
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Linking the signaling cascades and dynamic regulatory networks controlling stress responses.
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Genome Res
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2012
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1.14
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26
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DREM 2.0: Improved reconstruction of dynamic regulatory networks from time-series expression data.
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BMC Syst Biol
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2012
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1.11
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27
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Combined analysis reveals a core set of cycling genes.
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Genome Biol
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2007
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1.10
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28
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Combined static and dynamic analysis for determining the quality of time-series expression profiles.
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Nat Biotechnol
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2005
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1.09
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29
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Budding yeast SSD1-V regulates transcript levels of many longevity genes and extends chronological life span in purified quiescent cells.
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Mol Biol Cell
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2009
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1.09
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30
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Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1).
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PLoS One
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2011
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1.09
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31
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Probabilistic error correction for RNA sequencing.
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Nucleic Acids Res
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2013
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1.08
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32
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Reconstructing dynamic microRNA-regulated interaction networks.
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Proc Natl Acad Sci U S A
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2013
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1.01
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33
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MicroRNA regulation and its effects on cellular transcriptome in human immunodeficiency virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts.
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BMC Infect Dis
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2013
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1.00
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34
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A patient-gene model for temporal expression profiles in clinical studies.
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J Comput Biol
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2007
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0.98
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35
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DECOD: fast and accurate discriminative DNA motif finding.
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Bioinformatics
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2011
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0.98
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36
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Integrating sequence, expression and interaction data to determine condition-specific miRNA regulation.
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Bioinformatics
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2013
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0.97
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37
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Identifying cycling genes by combining sequence homology and expression data.
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Bioinformatics
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2006
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0.97
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38
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Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering.
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Genome Biol
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2010
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0.97
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39
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Algorithms in nature: the convergence of systems biology and computational thinking.
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Mol Syst Biol
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2011
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ExpressionBlast: mining large, unstructured expression databases.
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Nat Methods
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2013
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Inferring pairwise regulatory relationships from multiple time series datasets.
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Bioinformatics
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2007
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0.92
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Identifying proteins controlling key disease signaling pathways.
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Bioinformatics
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2013
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A high-throughput framework to detect synapses in electron microscopy images.
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Bioinformatics
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2013
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0.90
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A network-based approach for predicting missing pathway interactions.
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PLoS Comput Biol
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2012
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0.90
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45
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Systematic prediction of human membrane receptor interactions.
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Proteomics
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2009
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0.90
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46
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Cross-species queries of large gene expression databases.
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Bioinformatics
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2010
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0.89
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47
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Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells.
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BMC Syst Biol
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2013
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0.87
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48
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Discriminative motif finding for predicting protein subcellular localization.
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IEEE/ACM Trans Comput Biol Bioinform
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2011
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0.86
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49
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A combined expression-interaction model for inferring the temporal activity of transcription factors.
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J Comput Biol
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2009
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50
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Combination of genomic approaches with functional genetic experiments reveals two modes of repression of yeast middle-phase meiosis genes.
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BMC Genomics
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2010
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0.86
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Continuous hidden process model for time series expression experiments.
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Bioinformatics
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2007
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Computational methods for analyzing dynamic regulatory networks.
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Methods Mol Biol
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2010
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IL-3 and oncogenic Abl regulate the myeloblast transcriptome by altering mRNA stability.
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PLoS One
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2009
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Matching experiments across species using expression values and textual information.
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Bioinformatics
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2012
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cDREM: inferring dynamic combinatorial gene regulation.
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J Comput Biol
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2015
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Cross species expression analysis of innate immune response.
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J Comput Biol
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2010
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Learning cellular sorting pathways using protein interactions and sequence motifs.
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J Comput Biol
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2011
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Transcriptome analyses identify key cellular factors associated with HIV-1-associated neuropathogenesis in infected men.
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AIDS
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2017
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Topological properties of robust biological and computational networks.
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J R Soc Interface
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2014
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Preface: RECOMB Conference on Systems Biology, Regulatory Genomics, and DREAM Challenges 2010 special issue.
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J Comput Biol
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2011
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The SDREM Method for Reconstructing Signaling and Regulatory Response Networks: Applications for Studying Disease Progression.
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Methods Mol Biol
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2016
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