Xiaohua Gong

Author PubWeight™ 40.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ Res 2002 2.11
2 EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet 2009 1.82
3 Disruption of Gja8 (alpha8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation. Development 2002 1.72
4 Lens gap junctions in growth, differentiation, and homeostasis. Physiol Rev 2010 1.70
5 Optic nerve axon number in mouse is regulated by PAX2. J AAPOS 2007 1.39
6 A model for familial exudative vitreoretinopathy caused by LPR5 mutations. Hum Mol Genet 2008 1.36
7 A Gja8 (Cx50) point mutation causes an alteration of alpha 3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice. Hum Mol Genet 2002 1.28
8 Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice. Genetics 2004 1.28
9 Connections between connexins, calcium, and cataracts in the lens. J Gen Physiol 2004 1.23
10 Special fasciculiform cataract caused by a mutation in the gammaD-crystallin gene. Mol Vis 2004 1.17
11 Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis. Development 2006 1.10
12 GammaD-crystallin associated protein aggregation and lens fiber cell denucleation. Invest Ophthalmol Vis Sci 2007 1.06
13 The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium. Exp Cell Res 2009 1.04
14 Dominant cataracts result from incongruous mixing of wild-type lens connexins. J Cell Biol 2003 1.03
15 Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis. Mol Biol Cell 2009 1.03
16 The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins. J Cell Sci 2007 1.03
17 Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells. Exp Eye Res 2006 1.00
18 Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency. J Biol Chem 2005 0.99
19 Knock-in of alpha3 connexin prevents severe cataracts caused by an alpha8 point mutation. J Cell Sci 2006 0.99
20 Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency. Invest Ophthalmol Vis Sci 2006 0.94
21 Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice. Eur J Cell Biol 2006 0.94
22 Diverse roles of Eph/ephrin signaling in the mouse lens. PLoS One 2011 0.93
23 EphA2 and Src regulate equatorial cell morphogenesis during lens development. Development 2013 0.90
24 LRP5 is required for vascular development in deeper layers of the retina. PLoS One 2010 0.90
25 Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2. PLoS One 2012 0.88
26 Severe retinal degeneration caused by a novel rhodopsin mutation. Invest Ophthalmol Vis Sci 2009 0.88
27 Dense nuclear cataract caused by the gammaB-crystallin S11R point mutation. Invest Ophthalmol Vis Sci 2008 0.84
28 Papillorenal syndrome-causing missense mutations in PAX2/Pax2 result in hypomorphic alleles in mouse and human. PLoS Genet 2010 0.83
29 The role of Vldlr in intraretinal angiogenesis in mice. Invest Ophthalmol Vis Sci 2011 0.82
30 Gap junction communication influences intercellular protein distribution in the lens. Exp Eye Res 2008 0.82
31 Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis. J Biol Chem 2010 0.81
32 Connexin mediated cataract prevention in mice. PLoS One 2010 0.81
33 Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization. Invest Ophthalmol Vis Sci 2016 0.80
34 Mechanism of cataract formation in alphaA-crystallin Y118D mutation. Invest Ophthalmol Vis Sci 2009 0.80
35 An identical alphaA-crystallin mutation (R54C) leads to recessive cataracts in humans and mice. Am J Ophthalmol 2008 0.78
36 Correction: A Novel GJA8 Mutation (p.V44A) Causing Autosomal Dominant Congenital Cataract. PLoS One 2015 0.77
37 Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization. PLoS One 2013 0.76
38 Characterization of mouse mutants with abnormal RPE cells. Adv Exp Med Biol 2006 0.76
39 Enhancement of ubiquitin conjugation activity reduces intracellular aggregation of V76D mutant γD-crystallin. Invest Ophthalmol Vis Sci 2012 0.75