|
1
|
Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay.
|
Lancet
|
2011
|
2.60
|
|
2
|
Disease-associated prion protein oligomers inhibit the 26S proteasome.
|
Mol Cell
|
2007
|
2.01
|
|
3
|
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.
|
Biochem J
|
2008
|
1.77
|
|
4
|
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates.
|
J Proteome Res
|
2007
|
1.59
|
|
5
|
Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis.
|
PLoS One
|
2010
|
1.25
|
|
6
|
Efficient dissemination of prions through preferential transmission to nearby cells.
|
J Gen Virol
|
2007
|
1.15
|
|
7
|
The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC.
|
J Biol Chem
|
2004
|
1.14
|
|
8
|
Elongated oligomers assemble into mammalian PrP amyloid fibrils.
|
J Mol Biol
|
2006
|
1.10
|
|
9
|
PrP glycoforms are associated in a strain-specific ratio in native PrPSc.
|
J Gen Virol
|
2005
|
1.09
|
|
10
|
PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit.
|
Hum Mutat
|
2010
|
1.07
|
|
11
|
Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS).
|
PLoS One
|
2010
|
1.05
|
|
12
|
Highly sensitive, quantitative cell-based assay for prions adsorbed to solid surfaces.
|
Proc Natl Acad Sci U S A
|
2009
|
1.04
|
|
13
|
Spontaneous generation of mammalian prions.
|
Proc Natl Acad Sci U S A
|
2010
|
1.00
|
|
14
|
Definable equilibrium states in the folding of human prion protein.
|
Biochemistry
|
2005
|
0.99
|
|
15
|
PrPSc binding antibodies are potent inhibitors of prion replication in cell lines.
|
J Biol Chem
|
2004
|
0.99
|
|
16
|
The R1441C mutation alters the folding properties of the ROC domain of LRRK2.
|
Biochim Biophys Acta
|
2009
|
0.98
|
|
17
|
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4.
|
Biochem J
|
2006
|
0.98
|
|
18
|
Protein conformation significantly influences immune responses to prion protein.
|
J Immunol
|
2005
|
0.95
|
|
19
|
Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification.
|
Transfusion
|
2010
|
0.94
|
|
20
|
A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K.
|
Transfusion
|
2010
|
0.94
|
|
21
|
Folding kinetics of the human prion protein probed by temperature jump.
|
Proc Natl Acad Sci U S A
|
2009
|
0.94
|
|
22
|
A reassessment of copper(II) binding in the full-length prion protein.
|
Biochem J
|
2006
|
0.92
|
|
23
|
Pharmacological chaperone for the structured domain of human prion protein.
|
Proc Natl Acad Sci U S A
|
2010
|
0.90
|
|
24
|
A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay.
|
J Gen Virol
|
2010
|
0.90
|
|
25
|
Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc.
|
Biochim Biophys Acta
|
2007
|
0.90
|
|
26
|
Recombinant prion protein does not possess SOD-1 activity.
|
Biochem J
|
2005
|
0.87
|
|
27
|
Conformational properties of beta-PrP.
|
J Biol Chem
|
2009
|
0.87
|
|
28
|
The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease.
|
J Biol Chem
|
2010
|
0.86
|
|
29
|
Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation.
|
J Gen Virol
|
2006
|
0.86
|
|
30
|
A role of cellular prion protein in programming T-cell cytokine responses in disease.
|
FASEB J
|
2009
|
0.85
|
|
31
|
The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells.
|
Immunology
|
2008
|
0.85
|
|
32
|
The H187R mutation of the human prion protein induces conversion of recombinant prion protein to the PrP(Sc)-like form.
|
Biochemistry
|
2010
|
0.84
|
|
33
|
Inhibition of proteinase K activity by copper(II) ions.
|
Biochemistry
|
2007
|
0.81
|
|
34
|
Removal of the glycosylphosphatidylinositol anchor from PrP(Sc) by cathepsin D does not reduce prion infectivity.
|
Biochem J
|
2006
|
0.77
|
|
35
|
The human prion protein residue 129 polymorphism lies within a cluster of epitopes for T cell recognition.
|
J Neuropathol Exp Neurol
|
2006
|
0.75
|