Published in J Am Chem Soc on April 07, 2010
Phosphine-catalyzed asymmetric additions of malonate esters to {gamma}-substituted allenoates and allenamides. Proc Natl Acad Sci U S A (2010) 1.17
Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs. Chem Commun (Camb) (2013) 1.14
Application of a new chiral phosphepine to the catalytic asymmetric synthesis of highly functionalized cyclopentenes that bear an array of heteroatom-substituted quaternary stereocenters. J Am Chem Soc (2011) 1.14
Chiral phosphines in nucleophilic organocatalysis. Beilstein J Org Chem (2014) 1.01
Catalytic asymmetric C-N bond formation: phosphine-catalyzed intra- and intermolecular γ-addition of nitrogen nucleophiles to allenoates and alkynoates. Angew Chem Int Ed Engl (2013) 0.98
Enantioselective Carbon-Sulfur Bond Formation: γ Additions of Aryl Thiols to Allenoates Catalyzed by a Chiral Phosphepine. Chem Sci (2011) 0.93
Phosphine-Catalyzed Doubly Stereoconvergent γ-Additions of Racemic Heterocycles to Racemic Allenoates: The Catalytic Enantioselective Synthesis of Protected α,α-Disubstituted α-Amino Acid Derivatives. J Am Chem Soc (2015) 0.88
Highly enantioselective, intermolecular hydroamination of allenyl esters catalyzed by bifunctional phosphinothioureas. J Am Chem Soc (2014) 0.84
Stereoselective Syntheses of α,β-Unsaturated γ-Amino Esters Through Phosphine-Catalyzed γ-Umpolung Additions of Sulfonamides to γ-Substituted Allenoates. Tetrahedron Lett (2015) 0.80
Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts. Beilstein J Org Chem (2016) 0.75
Asymmetric cyanation of imines via dipeptide-derived organophosphine dual-reagent catalysis. Nat Commun (2016) 0.75
Catalytic Enantioselective Carbon-Oxygen Bond Formation: Phosphine-Catalyzed Synthesis of Benzylic Ethers via the Oxidation of Benzylic C-H Bonds. J Am Chem Soc (2016) 0.75
1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis. Beilstein J Org Chem (2016) 0.75
Reactions of electron-deficient alkynes and allenes under phosphine catalysis. Acc Chem Res (2001) 1.86
Phosphine-triggered synthesis of functionalized cyclic compounds. Chem Soc Rev (2008) 1.80
Phosphine-catalyzed enantioselective synthesis of oxygen heterocycles. Angew Chem Int Ed Engl (2009) 1.67
Enantioselective catalysis and complexity generation from allenoates. Chem Soc Rev (2009) 1.61
Asymmetric carbon-carbon bond formation gamma to a carbonyl group: phosphine-catalyzed addition of nitromethane to allenes. J Am Chem Soc (2009) 1.59
Enantioselective organocatalyzed alpha sulfenylation of aldehydes. Angew Chem Int Ed Engl (2005) 1.55
Phosphine-catalyzed annulation of thioamides and 2-alkynoates: a new synthesis of thiazolines. J Org Chem (2002) 1.22
Tandem reactions to construct heterocycles via phosphine-catalyzed umpolung addition and intramolecular conjugate addition. Org Lett (2002) 1.19
A chiral 1,2-bisphospholane ligand with a novel structural motif: applications in highly enantioselective Rh-catalyzed hydrogenations. Angew Chem Int Ed Engl (2002) 1.08
Dienamine catalysis: organocatalytic asymmetric gamma-amination of alpha,beta-unsaturated aldehydes. J Am Chem Soc (2006) 1.06
Catalytic asymmetric conjugate addition of simple alkyl thiols to alpha,beta-unsaturated N-acylated oxazolidin-2-ones with bifunctional catalysts. J Am Chem Soc (2009) 1.01
Exploiting organocatalysis: enantioselective synthesis of vinyl glycines by allylic sulfimide [2,3] sigmatropic rearrangement. Angew Chem Int Ed Engl (2007) 0.87
Palladium-catalyzed coupling reactions of aryl chlorides. Angew Chem Int Ed Engl (2002) 3.51
Enantioselective alkyl-alkyl Suzuki cross-couplings of unactivated homobenzylic halides. J Am Chem Soc (2008) 2.35
Catalytic asymmetric Hiyama cross-couplings of racemic alpha-bromo esters. J Am Chem Soc (2008) 2.33
Asymmetric nickel-catalyzed Negishi cross-couplings of secondary alpha-bromo amides with organozinc reagents. J Am Chem Soc (2005) 2.27
Suzuki cross-couplings of unactivated secondary alkyl bromides and iodides. J Am Chem Soc (2004) 2.09
Catalytic enantioselective Negishi reactions of racemic secondary benzylic halides. J Am Chem Soc (2005) 2.06
Nickel-catalyzed asymmetric negishi cross-couplings of secondary allylic chlorides with alkylzincs. J Am Chem Soc (2008) 2.03
Pd/P(t-Bu)(3): a mild and general catalyst for Stille reactions of aryl chlorides and aryl bromides. J Am Chem Soc (2002) 1.96
Catalytic asymmetric synthesis of piperidine derivatives through the [4 + 2] annulation of imines with allenes. J Am Chem Soc (2005) 1.94
Amino alcohols as ligands for nickel-catalyzed suzuki reactions of unactivated alkyl halides, including secondary alkyl chlorides, with arylboronic acids. J Am Chem Soc (2006) 1.87
Synthesis of functionalized cyclopentenes through catalytic asymmetric [3+2] cycloadditions of allenes with enones. Angew Chem Int Ed Engl (2006) 1.76
Phosphine-catalyzed enantioselective synthesis of oxygen heterocycles. Angew Chem Int Ed Engl (2009) 1.67
Nickel-catalyzed asymmetric cross-couplings of racemic propargylic halides with arylzinc reagents. J Am Chem Soc (2008) 1.65
Asymmetric carbon-carbon bond formation gamma to a carbonyl group: phosphine-catalyzed addition of nitromethane to allenes. J Am Chem Soc (2009) 1.59
Cross-couplings of unactivated secondary alkyl halides: room-temperature nickel-catalyzed Negishi reactions of alkyl bromides and iodides. J Am Chem Soc (2003) 1.58
Asymmetric alkyl-alkyl cross-couplings of unactivated secondary alkyl electrophiles: stereoconvergent Suzuki reactions of racemic acylated halohydrins. J Am Chem Soc (2010) 1.58
Catalytic asymmetric γ-alkylation of carbonyl compounds via stereoconvergent Suzuki cross-couplings. J Am Chem Soc (2011) 1.52
Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors. Proc Natl Acad Sci U S A (2011) 1.52
Nickel/bis(oxazoline)-catalyzed asymmetric Kumada reactions of alkyl electrophiles: cross-couplings of racemic alpha-bromoketones. J Am Chem Soc (2010) 1.52
Suzuki cross-couplings of alkyl tosylates that possess beta hydrogen atoms: synthetic and mechanistic studies. Angew Chem Int Ed Engl (2002) 1.51
Catalytic asymmetric cross-couplings of racemic alpha-bromoketones with arylzinc reagents. Angew Chem Int Ed Engl (2009) 1.47
Asymmetric Suzuki cross-couplings of activated secondary alkyl electrophiles: arylations of racemic alpha-chloroamides. J Am Chem Soc (2010) 1.46
Toward an improved understanding of the unusual reactivity of Pd0/trialkylphosphane catalysts in cross-couplings of alkyl electrophiles: quantifying the factors that determine the rate of oxidative addition. Angew Chem Int Ed Engl (2003) 1.40
A versatile method for Suzuki cross-coupling reactions of nitrogen heterocycles. Angew Chem Int Ed Engl (2006) 1.39
Stille cross-couplings of unactivated secondary alkyl halides using monoorganotin reagents. J Am Chem Soc (2005) 1.38
Stereoconvergent amine-directed alkyl-alkyl Suzuki reactions of unactivated secondary alkyl chlorides. J Am Chem Soc (2011) 1.36
New directing groups for metal-catalyzed asymmetric carbon-carbon bond-forming processes: stereoconvergent alkyl-alkyl Suzuki cross-couplings of unactivated electrophiles. J Am Chem Soc (2012) 1.34
Palladium-catalyzed negishi cross-coupling reactions of unactivated alkyl iodides, bromides, chlorides, and tosylates. J Am Chem Soc (2003) 1.32
Enantioselective Staudinger synthesis of beta-lactams catalyzed by a planar-chiral nucleophile. J Am Chem Soc (2002) 1.30
Alkyl-alkyl suzuki cross-couplings of unactivated secondary alkyl halides at room temperature. J Am Chem Soc (2007) 1.29
Boronic acids: new coupling partners in room-temperature Suzuki reactions of alkyl bromides. Crystallographic characterization of an oxidative-addition adduct generated under remarkably mild conditions. J Am Chem Soc (2002) 1.24
Elucidating reactivity differences in palladium-catalyzed coupling processes: the chemistry of palladium hydrides. J Am Chem Soc (2004) 1.24
Intramolecular Heck reactions of unactivated alkyl halides. J Am Chem Soc (2007) 1.23
Umpolung of Michael acceptors catalyzed by N-heterocyclic carbenes. J Am Chem Soc (2006) 1.23
Nickel-catalyzed Negishi arylations of propargylic bromides: a mechanistic investigation. J Am Chem Soc (2014) 1.22
Nickel-catalyzed carbon-carbon bond-forming reactions of unactivated tertiary alkyl halides: Suzuki arylations. J Am Chem Soc (2013) 1.21
Cu(I)/bis(azaferrocene)-catalyzed enantioselective synthesis of beta-lactams via couplings of alkynes with nitrones. J Am Chem Soc (2002) 1.18
Enantioconvergent cross-couplings of racemic alkylmetal reagents with unactivated secondary alkyl electrophiles: catalytic asymmetric Negishi α-alkylations of N-Boc-pyrrolidine. J Am Chem Soc (2013) 1.17
Catalytic enantioselective synthesis of oxindoles and benzofuranones that bear a quaternary stereocenter. Angew Chem Int Ed Engl (2003) 1.17
Phosphine-catalyzed asymmetric additions of malonate esters to {gamma}-substituted allenoates and allenamides. Proc Natl Acad Sci U S A (2010) 1.17
Nickel-catalyzed coupling reactions of alkyl electrophiles, including unactivated tertiary halides, to generate carbon-boron bonds. J Am Chem Soc (2012) 1.17
Enantioselective alkenylation via nickel-catalyzed cross-coupling with organozirconium reagents. J Am Chem Soc (2010) 1.16
A new copper-catalyzed [3 + 2] cycloaddition: enantioselective coupling of terminal alkynes with azomethine imines to generate five-membered nitrogen heterocycles. J Am Chem Soc (2003) 1.15
Application of a new chiral phosphepine to the catalytic asymmetric synthesis of highly functionalized cyclopentenes that bear an array of heteroatom-substituted quaternary stereocenters. J Am Chem Soc (2011) 1.14
Catalytic asymmetric Staudinger reactions to form beta-lactams: an unanticipated dependence of diastereoselectivity on the choice of the nitrogen substituent. J Am Chem Soc (2005) 1.13
Hiyama reactions of activated and unactivated secondary alkyl halides catalyzed by a nickel/norephedrine complex. Angew Chem Int Ed Engl (2007) 1.13
Alkyl-alkyl Suzuki cross-coupling of unactivated secondary alkyl chlorides. Angew Chem Int Ed Engl (2010) 1.12
Kinetic resolutions of azomethine imines via copper-catalyzed [3 + 2] cycloadditions. J Am Chem Soc (2005) 1.10
Copper-catalyzed asymmetric N-H insertion reactions: couplings of diazo compounds with carbamates to generate alpha-amino acids. J Am Chem Soc (2007) 1.10
Nickel/bis(oxazoline)-catalyzed asymmetric Negishi arylations of racemic secondary benzylic electrophiles to generate enantioenriched 1,1-diarylalkanes. J Am Chem Soc (2013) 1.09
Transition-metal-catalyzed alkylations of amines with alkyl halides: photoinduced, copper-catalyzed couplings of carbazoles. Angew Chem Int Ed Engl (2013) 1.08
Nickel-catalyzed enantioselective cross-couplings of racemic secondary electrophiles that bear an oxygen leaving group. J Am Chem Soc (2012) 1.08
Method for palladium-catalyzed cross-couplings of simple alkyl chlorides: Suzuki reactions catalyzed by [Pd2(dba)3]/PCy3. Angew Chem Int Ed Engl (2002) 1.07
Photoinduced Ullmann C-N coupling: demonstrating the viability of a radical pathway. Science (2012) 1.07
Catalytic enantioselective cross-couplings of secondary alkyl electrophiles with secondary alkylmetal nucleophiles: Negishi reactions of racemic benzylic bromides with achiral alkylzinc reagents. J Am Chem Soc (2012) 1.06
Catalytic enantioselective O-H insertion reactions. J Am Chem Soc (2006) 1.05
Asymmetric synthesis of highly substituted beta-lactones by nucleophile-catalyzed [2+2] cycloadditions of disubstituted ketenes with aldehydes. Angew Chem Int Ed Engl (2004) 1.05
Nickel-catalyzed cross-couplings of organosilicon reagents with unactivated secondary alkyl bromides. J Am Chem Soc (2004) 1.05
Kinetic resolutions of indolines by a nonenzymatic acylation catalyst. J Am Chem Soc (2006) 1.04
A straightforward and mild synthesis of functionalized 3-alkynoates. Angew Chem Int Ed Engl (2004) 1.04
Catalytic enantioselective synthesis of quaternary stereocenters via intermolecular C-acylation of silyl ketene acetals: dual activation of the electrophile and the nucleophile. J Am Chem Soc (2003) 1.03
Photoinduced, copper-catalyzed alkylation of amides with unactivated secondary alkyl halides at room temperature. J Am Chem Soc (2014) 1.02
A new family of nucleophiles for photoinduced, copper-catalyzed cross-couplings via single-electron transfer: reactions of thiols with aryl halides under mild conditions (O °C). J Am Chem Soc (2013) 1.01
Catalytic asymmetric synthesis of secondary nitriles via stereoconvergent Negishi arylations and alkenylations of racemic α-bromonitriles. J Am Chem Soc (2012) 1.00
A mild, palladium-catalyzed method for the dehydrohalogenation of alkyl bromides: synthetic and mechanistic studies. J Am Chem Soc (2012) 1.00
A versatile approach to Ullmann C-N couplings at room temperature: new families of nucleophiles and electrophiles for photoinduced, copper-catalyzed processes. J Am Chem Soc (2013) 0.99
Parallel kinetic resolution of 4-alkynals catalyzed by Rh(I)/Tol-BINAP: synthesis of enantioenriched cyclobutanones and cyclopentenones. J Am Chem Soc (2003) 0.99
Catalytic asymmetric synthesis of tertiary alkyl chlorides. Angew Chem Int Ed Engl (2007) 0.98
Catalytic asymmetric C-N bond formation: phosphine-catalyzed intra- and intermolecular γ-addition of nitrogen nucleophiles to allenoates and alkynoates. Angew Chem Int Ed Engl (2013) 0.98
Room-temperature Stille cross-couplings of alkenyltin reagents and functionalized alkyl bromides that possess beta hydrogens. J Am Chem Soc (2003) 0.95
Enantioselective nucleophilic catalysis: the synthesis of aza-beta-lactams through [2+2] cycloadditions of ketenes with azo compounds. Angew Chem Int Ed Engl (2008) 0.94
The first applications of carbene ligands in cross-couplings of alkyl electrophiles: sonogashira reactions of unactivated alkyl bromides and iodides. J Am Chem Soc (2003) 0.94
Catalytic asymmetric couplings of ketenes with aldehydes to generate enol esters. Angew Chem Int Ed Engl (2005) 0.94
Enantioselective Carbon-Sulfur Bond Formation: γ Additions of Aryl Thiols to Allenoates Catalyzed by a Chiral Phosphepine. Chem Sci (2011) 0.93
Nucleophile-catalyzed asymmetric acylations of silyl ketene imines: application to the enantioselective synthesis of verapamil. Angew Chem Int Ed Engl (2005) 0.93
Enantioselective synthesis of protected amines by the catalytic asymmetric addition of hydrazoic acid to ketenes. Angew Chem Int Ed Engl (2007) 0.90
Application of a new family of P,N ligands to the highly enantioselective hydrosilylation of aryl alkyl and dialkyl ketones. Angew Chem Int Ed Engl (2002) 0.90
Catalytic asymmetric synthesis of tertiary alkyl fluorides: Negishi cross-couplings of racemic α,α-dihaloketones. J Am Chem Soc (2014) 0.90
Nickel-catalyzed Negishi cross-couplings of secondary nucleophiles with secondary propargylic electrophiles at room temperature. Angew Chem Int Ed Engl (2008) 0.89
Stereoconvergent arylations and alkenylations of unactivated alkyl electrophiles: catalytic enantioselective synthesis of secondary sulfonamides and sulfones. J Am Chem Soc (2014) 0.89
Asymmetric [3 + 2] annulations catalyzed by a planar-chiral derivative of DMAP. Chem Commun (Camb) (2006) 0.88
Pd/P(t-Bu)(3)-Catalyzed Suzuki Cross-Couplings in the Presence of Water. Adv Synth Catal (2010) 0.87
A novel rhodium-catalyzed reduction-oxidation process: reaction of 4-alkynals with phenol to provide cis-4-alkenoates. Angew Chem Int Ed Engl (2002) 0.87
Biphenyl-derived phosphepines as chiral nucleophilic catalysts: enantioselective [4+1] annulations to form functionalized cyclopentenes. Angew Chem Int Ed Engl (2014) 0.86
Catalytic enantioselective construction of all-carbon quaternary stereocenters: synthetic and mechanistic studies of the C-acylation of silyl ketene acetals. J Am Chem Soc (2005) 0.86
Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition. J Am Chem Soc (2012) 0.86
Cross-couplings of alkyl electrophiles under "ligandless" conditions: Negishi reactions of organozirconium reagents. J Am Chem Soc (2004) 0.86
PALLADIUM-CATALYZED ALKYL-ALKYL SUZUKI CROSS-COUPLINGS OF PRIMARY ALKYL BROMIDES AT ROOM-TEMPERATURE: (13-CHLOROTRIDECYLOXY)TRIETHYLSILANE [Silane, [(13-chlorotridecyl)oxy]triethyl-]. Organic Synth (2010) 0.85
A unique rhodium-catalyzed rearrangement process: isomerization of an alkyne to a 1,3-diene with concomitant migration of a formyl group. An expeditious route to dienals from readily available 4-alkynals. Chem Commun (Camb) (2002) 0.84
Catalytic asymmetric synthesis of esters from ketenes. J Am Chem Soc (2005) 0.84
Enantioselective synthesis of cyclopentenones via rhodium-catalyzed kinetic resolution and desymmetrization of 4-alkynals. J Am Chem Soc (2002) 0.83
Enantioselective nucleophile-catalyzed synthesis of tertiary alkyl fluorides via the α-fluorination of ketenes: synthetic and mechanistic studies. J Am Chem Soc (2014) 0.82
Nonenzymatic dynamic kinetic resolution of secondary alcohols via enantioselective acylation: synthetic and mechanistic studies. J Am Chem Soc (2012) 0.82
Enantioselective addition of amines to ketenes catalyzed by a planar-chiral derivative of PPY: possible intervention of chiral Brønsted-acid catalysis. J Am Chem Soc (2002) 0.82
NICKEL-CATALYZED ENANTIOSELECTIVE NEGISHI CROSS-COUPLINGS OF RACEMIC SECONDARY α-BROMO AMIDES WITH ALKYLZINC REAGENTS: (S)-N-BENZYL-7-CYANO-2-ETHYL-N-PHENYLHEPTANAMIDE. Organic Synth (2010) 0.81
Catalytic enantioselective cyclization/cross-coupling with alkyl electrophiles. J Am Chem Soc (2014) 0.80
NICKEL-CATALYZED ASYMMETRIC NEGISHI CROSS-COUPLINGS OF RACEMIC SECONDARY ALLYLIC CHLORIDES WITH ALKYLZINCS: (S,E)-ETHYL 6-(1,3-DIOXOLAN-2-YL)-4-METHYLHEX-2-ENOATE. Organic Synth (2010) 0.80
Catalytic asymmetric cycloaddition of ketenes and nitroso compounds: enantioselective synthesis of alpha-hydroxycarboxylic acid derivatives. Angew Chem Int Ed Engl (2009) 0.80
Room-temperature Hiyama cross-couplings of arylsilanes with alkyl bromides and iodides. J Am Chem Soc (2003) 0.80
Ligands for palladium-catalyzed cross-couplings of alkyl halides: use of an alkyldiaminophosphane expands the scope of the Stille reaction. Angew Chem Int Ed Engl (2003) 0.79