Published in Mol Cell on March 12, 2010
Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nat Struct Mol Biol (2010) 2.40
Coordinated control of replication and transcription by a SAPK protects genomic integrity. Nature (2012) 2.28
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst) (2011) 1.45
RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. Nat Struct Mol Biol (2011) 1.36
Rescuing stalled or damaged replication forks. Cold Spring Harb Perspect Biol (2013) 1.34
Recovery of arrested replication forks by homologous recombination is error-prone. PLoS Genet (2012) 1.05
The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts. Genes Dev (2014) 0.99
Emerging critical roles of Fe-S clusters in DNA replication and repair. Biochim Biophys Acta (2015) 0.96
Homologous recombination as a replication fork escort: fork-protection and recovery. Biomolecules (2012) 0.94
Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid. PLoS Genet (2013) 0.88
Is homologous recombination really an error-free process? Front Genet (2014) 0.85
Recombination and replication. Cold Spring Harb Perspect Biol (2014) 0.83
Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability. Nucleic Acids Res (2011) 0.81
RNA polymerase II contributes to preventing transcription-mediated replication fork stalls. EMBO J (2014) 0.80
The role of CSM3, MRC1, and TOF1 in minisatellite stability and large loop DNA repair during meiosis in yeast. Fungal Genet Biol (2012) 0.79
The rem mutations in the ATP-binding groove of the Rad3/XPD helicase lead to Xeroderma pigmentosum-Cockayne syndrome-like phenotypes. PLoS Genet (2014) 0.79
Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity. Cell Cycle (2014) 0.77
Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1. Proc Natl Acad Sci U S A (2011) 0.76
A unified model for the molecular basis of Xeroderma pigmentosum-Cockayne Syndrome. Rare Dis (2015) 0.76
Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications. Nucleic Acids Res (2015) 0.76
High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast. PLoS Genet (2016) 0.76
Rescue from replication stress during mitosis. Cell Cycle (2017) 0.75
Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase. G3 (Bethesda) (2015) 0.75
Genome stability in the uvh6 mutant of Arabidopsis thaliana. Plant Cell Rep (2014) 0.75
The Role of PALB2 in the DNA Damage Response and Cancer Predisposition. Int J Mol Sci (2017) 0.75
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell (2003) 5.48
CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature (2008) 3.96
The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell (2011) 2.65
Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol Cell (2011) 2.59
Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J (2005) 2.32
Coordinated control of replication and transcription by a SAPK protects genomic integrity. Nature (2012) 2.28
R loops are linked to histone H3 S10 phosphorylation and chromatin condensation. Mol Cell (2013) 1.95
Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex. Mol Cell Biol (2006) 1.73
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability. Mol Cell (2005) 1.72
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination. Nat Cell Biol (2006) 1.71
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus. Chromosoma (2008) 1.69
The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange. EMBO Rep (2004) 1.68
Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation. J Biol Chem (2003) 1.63
Molecular evidence indicating that the yeast PAF complex is required for transcription elongation. EMBO Rep (2004) 1.58
Mitotic recombination in Saccharomyces cerevisiae. Curr Genet (2002) 1.55
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep (2006) 1.51
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability. Mol Biol Cell (2008) 1.51
Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles. EMBO J (2011) 1.49
Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast. Mol Cell (2003) 1.49
Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J (2003) 1.48
Genome instability and transcription elongation impairment in human cells depleted of THO/TREX. PLoS Genet (2011) 1.41
The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development. PLoS One (2012) 1.38
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. Proc Natl Acad Sci U S A (2007) 1.34
Impairment of transcription elongation by R-loops in vitro. Biochem Biophys Res Commun (2007) 1.32
The interface between transcription and mRNP export: from THO to THSC/TREX-2. Biochim Biophys Acta (2010) 1.32
Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae. Genetics (2002) 1.26
The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants. Mol Cell Biol (2009) 1.26
Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery. J Cell Biol (2009) 1.25
mRNA processing and genomic instability. Nat Struct Mol Biol (2005) 1.19
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions. Nat Struct Mol Biol (2011) 1.16
Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Mol Cell Biol (2012) 1.15
An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination. Mol Cell Biol (2006) 1.14
Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet (2009) 1.13
Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor. EMBO J (2012) 1.08
Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity. Mol Genet Genomics (2007) 1.08
Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae. Yeast (2003) 1.07
The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces cerevisiae. Genetics (2009) 1.06
New clues to understand the role of THO and other functionally related factors in mRNP biogenesis. Biochim Biophys Acta (2011) 1.05
A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J (2011) 1.04
Partial depletion of histone H4 increases homologous recombination-mediated genetic instability. Mol Cell Biol (2005) 1.04
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants. Mol Cell Biol (2006) 1.04
The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability. Genes Dev (2013) 1.03
Chromosomal translocations caused by either pol32-dependent or pol32-independent triparental break-induced replication. Mol Cell Biol (2009) 1.02
R-loops cause replication impairment and genome instability during meiosis. EMBO Rep (2012) 1.00
Transcription-associated genome instability. Chem Rev (2013) 1.00
The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress. Mol Biol Cell (2009) 1.00
AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants. PLoS Genet (2011) 1.00
The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts. Genes Dev (2014) 0.99
Control of cross-over by single-strand DNA resection. Trends Genet (2003) 0.98
Characterization of two highly similar Rad51 homologs of Physcomitrella patens. J Mol Biol (2002) 0.98
A new connection of mRNP biogenesis and export with transcription-coupled repair. Nucleic Acids Res (2007) 0.96
Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers. BMC Cancer (2011) 0.96
Transcription coupled repair at the interface between transcription elongation and mRNP biogenesis. Biochim Biophys Acta (2012) 0.96
Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases. PLoS Genet (2012) 0.93
R-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity. PLoS One (2013) 0.92
Nab2 functions in the metabolism of RNA driven by polymerases II and III. Mol Biol Cell (2011) 0.92
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication. Nucleic Acids Res (2007) 0.91
A novel class of mRNA-containing cytoplasmic granules are produced in response to UV-irradiation. Mol Biol Cell (2008) 0.91
A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants. Mol Genet Genomics (2008) 0.89
A novel yeast mutation, rad52-L89F, causes a specific defect in Rad51-independent recombination that correlates with a reduced ability of Rad52-L89F to interact with Rad59. Genetics (2004) 0.89
Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res (2011) 0.88
Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid. PLoS Genet (2013) 0.88
Defective nucleotide excision repair in yeast hpr1 and tho2 mutants. Nucleic Acids Res (2002) 0.87
Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination. Nucleic Acids Res (2012) 0.86
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation. Mol Cell Biol (2010) 0.85
Methods to study transcription-coupled repair in chromatin. Methods Mol Biol (2009) 0.85
SMC proteins, new players in the maintenance of genomic stability. Cell Cycle (2007) 0.84
Transcription at the proximity of the nuclear pore: a role for the THP1-SAC3-SUS1-CDC31 (THSC) complex. RNA Biol (2009) 0.82
Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability. Nucleic Acids Res (2011) 0.81
R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX. Nucleic Acids Res (2009) 0.81
The THO complex as a key mRNP biogenesis factor in development and cell differentiation. J Biol (2010) 0.79
Genetic and molecular analysis of mitotic recombination in Saccharomyces cerevisiae. Methods Mol Biol (2011) 0.78
Yeast pol4 promotes tel1-regulated chromosomal translocations. PLoS Genet (2013) 0.77
Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1. Proc Natl Acad Sci U S A (2011) 0.76
Methods to study transcription-coupled repair in chromatin. Methods Mol Biol (2015) 0.76
Correction: The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development. PLoS One (2016) 0.75