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1
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Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.
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J Natl Cancer Inst
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2010
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4.54
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2
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Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.
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Nat Genet
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2009
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4.47
|
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3
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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
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Nat Genet
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2012
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3.19
|
|
4
|
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
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J Natl Cancer Inst
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2011
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3.05
|
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5
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A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.
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Cell
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2013
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2.60
|
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6
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Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk.
|
Nat Genet
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2010
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2.47
|
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7
|
Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
|
J Pathol
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2011
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2.45
|
|
8
|
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.
|
Nat Genet
|
2012
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2.25
|
|
9
|
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission.
|
Cancer Res
|
2003
|
2.24
|
|
10
|
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.
|
Gastroenterology
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2008
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1.79
|
|
11
|
Distinct expression profile in fumarate-hydratase-deficient uterine fibroids.
|
Hum Mol Genet
|
2005
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1.26
|
|
12
|
Deciphering the 8q24.21 association for glioma.
|
Hum Mol Genet
|
2013
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1.08
|
|
13
|
CYP3A variation, premenopausal estrone levels, and breast cancer risk.
|
J Natl Cancer Inst
|
2012
|
1.06
|
|
14
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Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk.
|
Blood
|
2010
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1.02
|
|
15
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Effect of genome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk.
|
Lancet Oncol
|
2010
|
1.01
|
|
16
|
Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.
|
Hum Mol Genet
|
2013
|
1.00
|
|
17
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Investigation of the Birt-Hogg-Dube tumour suppressor gene (FLCN) in familial and sporadic colorectal cancer.
|
J Med Genet
|
2010
|
0.97
|
|
18
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Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.
|
Cancer Res
|
2008
|
0.96
|
|
19
|
Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair.
|
Carcinogenesis
|
2005
|
0.95
|
|
20
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7q deletion mapping and expression profiling in uterine fibroids.
|
Oncogene
|
2005
|
0.92
|
|
21
|
A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.
|
BMC Genomics
|
2013
|
0.91
|
|
22
|
Current morphologic criteria perform poorly in identifying hereditary leiomyomatosis and renal cell carcinoma syndrome-associated uterine leiomyomas.
|
Int J Gynecol Pathol
|
2014
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0.78
|
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23
|
Erratum: A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
|
Sci Rep
|
2015
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0.76
|
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24
|
A novel test for gene-ancestry interactions in genome-wide association data.
|
PLoS One
|
2012
|
0.75
|