Xavier Morelli

Author PubWeight™ 22.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nat Struct Biol 2003 1.68
2 Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci U S A 2007 1.34
3 Atomic analysis of protein-protein interfaces with known inhibitors: the 2P2I database. PLoS One 2010 1.29
4 2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions. Nucleic Acids Res 2012 1.25
5 Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR. FEBS Lett 2009 1.00
6 Impact of geocoding methods on associations between long-term exposure to urban air pollution and lung function. Environ Health Perspect 2013 0.96
7 Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16. J Biol Chem 2010 0.93
8 Structural and genetic analyses reveal a key role in prophage excision for the TorI response regulator inhibitor. J Biol Chem 2005 0.90
9 Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step. Antiviral Res 2009 0.87
10 GFscore: a general nonlinear consensus scoring function for high-throughput docking. J Chem Inf Model 2006 0.85
11 The cytochrome c3-[Fe]-hydrogenase electron-transfer complex: structural model by NMR restrained docking. FEBS Lett 2003 0.82
12 The type I/type II cytochrome c3 complex: an electron transfer link in the hydrogen-sulfate reduction pathway. J Mol Biol 2005 0.82
13 Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity. J Med Chem 2010 0.82
14 Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments. PLoS One 2013 0.81
15 A specific protein disorder catalyzer of HIV-1 Nef. Bioorg Med Chem 2011 0.81
16 Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X. Biochem J 2010 0.81
17 Multiple orientations in a physiological complex: the pyruvate-ferredoxin oxidoreductase-ferredoxin system. Biochemistry 2004 0.81
18 2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine. J R Soc Interface 2013 0.80
19 Protein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets. Comb Chem High Throughput Screen 2009 0.80
20 An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity. Bioorg Med Chem 2010 0.79
21 The crystal structure of the hexadeca-heme cytochrome Hmc and a structural model of its complex with cytochrome c(3). Structure 2002 0.79
22 Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space. Future Med Chem 2014 0.79
23 A peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama V(HH) domain. Biochem J 2002 0.78
24 Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix). FEBS Lett 2012 0.78
25 Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex. Protein Sci 2006 0.75
26 Sequential NMR assignment of the ferri-cytochrome c3 from Desulfovibrio vulgaris Hildenborough. J Biomol NMR 2002 0.75
27 Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides. Biochimie 2012 0.75
28 Stereoselective synthesis of original spirolactams displaying promising folded structures. Org Biomol Chem 2013 0.75