Scot W Ebbinghaus

Author PubWeight™ 26.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013 18.08
2 Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter. Biochemistry 2005 2.27
3 A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity. Nucleic Acids Res 2008 1.49
4 Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands. J Am Chem Soc 2009 1.42
5 PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions. Bioconjug Chem 2006 0.92
6 Voreloxin, a first-in-class anticancer quinolone derivative, in relapsed/refractory solid tumors: a report on two dosing schedules. Clin Cancer Res 2010 0.91
7 Peptide nucleic acid conjugates: synthesis, properties and applications. Curr Top Med Chem 2005 0.90
8 Targeting and regulation of the HER-2/neu oncogene promoter with bis-peptide nucleic acids. Oligonucleotides 2005 0.80
9 A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity. Biochemistry 2003 0.77
10 Tolerability, safety and pharmacokinetics of ridaforolimus in combination with bicalutamide in patients with asymptomatic, metastatic castration-resistant prostate cancer (CRPC). Cancer Chemother Pharmacol 2013 0.76
11 Mechanism of PNA transport to the nuclear compartment. Ann N Y Acad Sci 2006 0.75
12 Synthesis and evaluation of a triplex-forming oligonucleotide-pyrrolobenzodiazepine conjugate. Bioconjug Chem 2004 0.75