Stephen R Holdsworth

Author PubWeight™ 73.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction. Kidney Int 2012 2.47
2 Lung T-cell responses to nontypeable Haemophilus influenzae in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol 2012 2.10
3 Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. J Am Soc Nephrol 2010 2.03
4 Adaptive immunity to nontypeable Haemophilus influenzae. Am J Respir Crit Care Med 2002 1.83
5 The Th17-defining transcription factor RORγt promotes glomerulonephritis. J Am Soc Nephrol 2010 1.67
6 IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen. J Am Soc Nephrol 2009 1.62
7 Th1 and Th17 cells induce proliferative glomerulonephritis. J Am Soc Nephrol 2009 1.55
8 Microbiologic follow-up study in adult bronchiectasis. Respir Med 2007 1.52
9 Anti-neutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in anti-myeloperoxidase crescentic glomerulonephritis. J Am Soc Nephrol 2006 1.49
10 Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis. J Am Soc Nephrol 2012 1.49
11 T cells in crescentic glomerulonephritis. J Am Soc Nephrol 2006 1.45
12 Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis. J Am Soc Nephrol 2003 1.22
13 T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis. J Am Soc Nephrol 2008 1.20
14 IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment. J Am Soc Nephrol 2005 1.20
15 Intrinsic renal cells are the major source of tumor necrosis factor contributing to renal injury in murine crescentic glomerulonephritis. J Am Soc Nephrol 2003 1.19
16 Experimental autoimmune Goodpasture's disease: a pathogenetic role for both effector cells and antibody in injury. Kidney Int 2005 1.18
17 Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma. J Am Soc Nephrol 2004 1.14
18 Characterisation of the onset and presenting clinical features of adult bronchiectasis. Respir Med 2006 1.10
19 Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis. J Am Soc Nephrol 2007 1.10
20 Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. Am J Pathol 2004 1.06
21 Outcome in adult bronchiectasis. COPD 2005 1.06
22 IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis. Nephrol Dial Transplant 2009 1.03
23 Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis. Arthritis Rheum 2011 1.03
24 IFN-gamma production by intrinsic renal cells and bone marrow-derived cells is required for full expression of crescentic glomerulonephritis in mice. J Immunol 2002 1.02
25 The emergence of TH17 cells as effectors of renal injury. J Am Soc Nephrol 2011 1.02
26 Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis. J Am Soc Nephrol 2003 1.02
27 Endogenous foxp3(+) T-regulatory cells suppress anti-glomerular basement membrane nephritis. Kidney Int 2011 1.01
28 T cells in glomerulonephritis. Springer Semin Immunopathol 2003 1.01
29 Contributions of IL-1beta and IL-1alpha to crescentic glomerulonephritis in mice. J Am Soc Nephrol 2004 1.00
30 Advances in the pathogenesis of Goodpasture's disease: from epitopes to autoantibodies to effector T cells. J Autoimmun 2008 0.98
31 The requirement for granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in leukocyte-mediated immune glomerular injury. J Am Soc Nephrol 2002 0.96
32 Tim-1 promotes cisplatin nephrotoxicity. Am J Physiol Renal Physiol 2011 0.96
33 Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis. Kidney Int 2010 0.96
34 The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Proc Natl Acad Sci U S A 2012 0.96
35 A pathogenetic role for mast cells in experimental crescentic glomerulonephritis. J Am Soc Nephrol 2005 0.95
36 An IL-12-independent role for CD40-CD154 in mediating effector responses: studies in cell-mediated glomerulonephritis and dermal delayed-type hypersensitivity. J Immunol 2004 0.94
37 Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function. Blood 2013 0.94
38 CD80 and CD86 costimulatory molecules regulate crescentic glomerulonephritis by different mechanisms. Kidney Int 2005 0.94
39 Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. J Am Soc Nephrol 2005 0.94
40 CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis. J Immunol 2006 0.93
41 Phenotypes of adult bronchiectasis: onset of productive cough in childhood and adulthood. COPD 2009 0.92
42 Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis. Kidney Int 2011 0.91
43 Granulocyte macrophage colony-stimulating factor expression by both renal parenchymal and immune cells mediates murine crescentic glomerulonephritis. J Am Soc Nephrol 2005 0.90
44 The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease. J Immunol Methods 2005 0.90
45 Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis. Am J Pathol 2010 0.90
46 The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. J Am Soc Nephrol 2013 0.89
47 Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells. J Am Soc Nephrol 2008 0.89
48 Mast cells mediate acute kidney injury through the production of TNF. J Am Soc Nephrol 2011 0.89
49 Distinct in vivo roles of CD80 and CD86 in the effector T-cell responses inducing antigen-induced arthritis. Immunology 2008 0.89
50 Laboratory assessment of immune function in renal transplant patients. Nephrol Dial Transplant 2003 0.88
51 Inducible co-stimulatory molecule ligand is protective during the induction and effector phases of crescentic glomerulonephritis. J Am Soc Nephrol 2006 0.87
52 Review: T helper 17 cells: their role in glomerulonephritis. Nephrology (Carlton) 2010 0.87
53 Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology 2009 0.86
54 Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis. Am J Pathol 2011 0.86
55 Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice. Am J Pathol 2011 0.86
56 The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses. Am J Pathol 2011 0.86
57 Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis. Cell Immunol 2013 0.85
58 T cell mediated autoimmune glomerular disease in mice. Curr Protoc Immunol 2014 0.83
59 Leukocyte phenotype and function predicts infection risk in renal transplant recipients. Nephrol Dial Transplant 2005 0.83
60 Fibrin independent proinflammatory effects of tissue factor in experimental crescentic glomerulonephritis. Kidney Int 2004 0.81
61 Cytokines in glomerulonephritis. Semin Nephrol 2007 0.80
62 Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN. J Am Soc Nephrol 2013 0.80
63 Endogenous myeloperoxidase is a mediator of joint inflammation and damage in experimental arthritis. Arthritis Rheumatol 2014 0.79
64 Lung diffusing capacity in adult bronchiectasis: a longitudinal study. Respir Care 2010 0.78
65 Endogenous IL-13 limits humoral responses and injury in experimental glomerulonephritis but does not regulate Th1 cell-mediated crescentic glomerulonephritis. J Am Soc Nephrol 2004 0.78
66 Glomerulonephritis Induced by Heterologous Anti-GBM Globulin as a Planted Foreign Antigen. Curr Protoc Immunol 2014 0.77
67 Ex vivo lymphocyte proliferative function is severely inhibited in renal transplant patients on mycophenolate mofetil treatment. Transpl Immunol 2004 0.75
68 Reply: To PMID 23142009. J Allergy Clin Immunol 2013 0.75
69 Chest pain and exacerbations of bronchiectasis. Int J Gen Med 2012 0.75
70 Targeting IL-17 and IL-23 in Immune Mediated Renal Disease. Curr Med Chem 2015 0.75
71 Atorvastatin enhances humoral immune responses but does not alter renal injury in experimental crescentic glomerulonephritis. Nephrology (Carlton) 2009 0.75
72 Interleukin-17RA Promotes Humoral Responses and Glomerular Injury in Experimental Rapidly Progressive Glomerulonephritis. Nephron 2016 0.75
73 The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis. Nephrol Dial Transplant 2004 0.75
74 Activated Renal Dendritic Cells Cross Present Intrarenal Antigens After Ischemia-Reperfusion Injury. Transplantation 2017 0.75