Published in Arch Intern Med on March 22, 2010
QTc prolongation by psychotropic drugs and the risk of Torsade de Pointes. Dtsch Arztebl Int (2011) 1.93
Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem. Ther Adv Psychopharmacol (2013) 0.90
Stereoselective Inhibition of the hERG1 Potassium Channel. Front Pharmacol (2010) 0.83
Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis. PLoS One (2014) 0.83
ICH E14 Q&A(R2) document: commentary on the further updated recommendations on thorough QT studies. Br J Clin Pharmacol (2015) 0.82
Practicability, safety, and efficacy of a "German model" for opioid conversion to oral levo-methadone. Support Care Cancer (2011) 0.82
Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort. OMICS (2013) 0.81
Pharmacokinetic interaction between telaprevir and methadone. Antimicrob Agents Chemother (2013) 0.81
Regulation of ecto-apyrase CD39 (ENTPD1) expression by phosphodiesterase III (PDE3). FASEB J (2013) 0.81
(R)-methadone versus racemic methadone: what is best for patient care? Addiction (2011) 0.80
Evaluation of QTc interval in Iranian causalities (Janbazan) of Iran-Iraq war receiving maintenance methadone treatment. J Res Med Sci (2012) 0.79
CSAT's QT interval screening in methadone report: outrageous fortune or sea of troubles? J Addict Dis (2011) 0.79
A systematic review of the cardiotoxicity of methadone. EXCLI J (2015) 0.79
Hepatitis C virus infection influences the S-methadone metabolite plasma concentration. PLoS One (2013) 0.78
[Accidental levomethadone intoxication in a palliative patient]. Schmerz (2012) 0.78
Does methadone prolong QTc intervals by depleting testosterone levels? Arch Intern Med (2010) 0.75
Tell-Tale SNPs: The Role of CYP2B6 in Methadone Fatalities. J Anal Toxicol (2017) 0.75
Personalized prescribing: a new medical model for clinical implementation of psychotropic drugs. Dialogues Clin Neurosci (2016) 0.75
The Impact of Opioids on Cardiac Electrophysiology. Curr Cardiol Rev (2016) 0.75
False sense of safety by daily QTc interval monitoring during methadone IVPCA titration in a patient with chronic pain. J Pain Res (2013) 0.75
Pharmacogenomic considerations in opioid analgesia. Pharmgenomics Pers Med (2012) 0.75
[Drug interactions in pain therapy]. Schmerz (2015) 0.75
Ischemic Cerebroprotection Conferred by Myeloid Lineage-Restricted or Global CD39 Transgene Expression. Circulation (2017) 0.75
Comparison of the glomerular filtration rate in children by the new revised Schwartz formula and a new generalized formula. Kidney Int (2012) 3.40
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet (2002) 3.32
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Dominant TNF-α+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease. Nat Med (2011) 2.77
Mephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issues. Psychopharmacology (Berl) (2010) 1.94
In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogenet Genomics (2009) 1.79
Social and medical vulnerability factors of emergency department frequent users in a universal health insurance system. Acad Emerg Med (2012) 1.72
Status epilepticus: impact of therapeutic coma on outcome. Crit Care Med (2015) 1.70
Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovasc Res (2005) 1.66
Counsellor behaviours and patient language during brief motivational interventions: a sequential analysis of speech. Addiction (2008) 1.58
Who drinks most of the total alcohol in young men--risky single occasion drinking as normative behaviour. Alcohol Alcohol (2008) 1.57
J-shaped association between serum glucose and functional outcome in acute ischemic stroke. Stroke (2010) 1.54
ABCB1 and cytochrome P450 genotypes and phenotypes: influence on methadone plasma levels and response to treatment. Clin Pharmacol Ther (2006) 1.49
New electrocardiographic criteria for discriminating between Brugada types 2 and 3 patterns and incomplete right bundle branch block. J Am Coll Cardiol (2011) 1.48
Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment. Clin Pharmacol Ther (2005) 1.45
Prediction of Large Vessel Occlusions in Acute Stroke: National Institute of Health Stroke Scale Is Hard to Beat. Crit Care Med (2016) 1.44
Multicenter study on the clinical effectiveness, pharmacokinetics, and pharmacogenetics of mirtazapine in depression. J Clin Psychopharmacol (2012) 1.44
Importance of early weight changes to predict long-term weight gain during psychotropic drug treatment. J Clin Psychiatry (2015) 1.40
Counselor motivational interviewing skills and young adult change talk articulation during brief motivational interventions. J Subst Abuse Treat (2010) 1.38
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Addict Biol (2011) 1.37
Counselor skill influences outcomes of brief motivational interventions. J Subst Abuse Treat (2009) 1.29
Does change talk during brief motivational interventions with young men predict change in alcohol use? J Subst Abuse Treat (2012) 1.13
Topical review on the abuse and misuse potential of tramadol and tilidine in Germany. Subst Abus (2013) 1.13
Promoting innovation and excellence to face the rapid diffusion of novel psychoactive substances in the EU: the outcomes of the ReDNet project. Hum Psychopharmacol (2013) 1.12
Feasibility and outcome of substitution treatment of heroin-dependent patients in specialized substitution centers and primary care facilities in Germany: a naturalistic study in 2694 patients. Drug Alcohol Depend (2008) 1.08
Designer drugs on the internet: a phenomenon out-of-control? the emergence of hallucinogenic drug Bromo-Dragonfly. Curr Clin Pharmacol (2011) 1.08
Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs. J Virol (2008) 1.08
Association between inhibitory control capacity and body weight in overweight and obese children and adolescents: dependence on age and inhibitory control component. Child Neuropsychol (2010) 1.07
Change talk sequence during brief motivational intervention, towards or away from drinking. Addiction (2010) 1.07
Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients. Eur J Clin Pharmacol (2005) 1.06
Identifying emerging trends in recreational drug use; outcomes from the Psychonaut Web Mapping Project. Prog Neuropsychopharmacol Biol Psychiatry (2012) 1.05
The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test. Pharmacogenet Genomics (2009) 1.05
CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients. Ther Drug Monit (2008) 1.04
Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data. Psychother Psychosom (2011) 1.04
ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine. J Clin Psychopharmacol (2009) 1.03
Factors associated with latent tuberculosis among asylum seekers in Switzerland: a cross-sectional study in Vaud County. BMC Infect Dis (2012) 1.02
Treating childhood obesity: family background variables and the child's success in a weight-control intervention. Int J Eat Disord (2009) 1.02
Effect of age and gender on citalopram and desmethylcitalopram steady-state plasma concentrations in adults and elderly depressed patients. Prog Neuropsychopharmacol Biol Psychiatry (2005) 1.01
Prevalence of substance use in a Swiss psychiatric hospital: interview reports and urine screening. Addict Behav (2005) 1.01
CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins. Gastroenterology (2011) 1.01
Phenomenon of new drugs on the Internet: the case of ketamine derivative methoxetamine. Hum Psychopharmacol (2012) 1.01
Determination of unbound antiretroviral drug concentrations by a modified ultrafiltration method reveals high variability in the free fraction. Ther Drug Monit (2008) 1.01
Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: a pilot study. Pharmacol Res (2008) 0.99
The Acute STroke Registry and Analysis of Lausanne (ASTRAL): design and baseline analysis of an ischemic stroke registry including acute multimodal imaging. Stroke (2010) 0.99
Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients. Pharmacogenet Genomics (2008) 0.99
Disentangling structural brain alterations associated with violent behavior from those associated with substance use disorders. Arch Gen Psychiatry (2011) 0.98
Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: relationship with S-citalopram concentrations in plasma and cerebrospinal fluid (CSF) and clinical response. Psychopharmacology (Berl) (2005) 0.98
Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers. J Clin Psychopharmacol (2002) 0.96
Craving in alcohol-dependent patients after detoxification is related to glutamatergic dysfunction in the nucleus accumbens and the anterior cingulate cortex. Neuropsychopharmacology (2013) 0.95
CYP2D6 and ABCB1 genetic variability: influence on paroxetine plasma level and therapeutic response. Ther Drug Monit (2008) 0.95
Does inhibitory control capacity in overweight and obese children and adolescents predict success in a weight-reduction program? Eur Child Adolesc Psychiatry (2009) 0.94
Perception of the amount of drinking by others in a sample of 20-year-old men: the more I think you drink, the more I drink. Alcohol Alcohol (2010) 0.94
Degree of cross-genotype reactivity of hepatitis C virus-specific CD8+ T cells directed against NS3. Hepatology (2009) 0.93
Association of dopamine and opioid receptor genetic polymorphisms with response to methadone maintenance treatment. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.93
Efficacy of brief motivational intervention in reducing binge drinking in young men: A randomized controlled trial. Drug Alcohol Depend (2010) 0.92
Drugs on the web; the Psychonaut 2002 EU project. Prog Neuropsychopharmacol Biol Psychiatry (2006) 0.92
Enantiomers' potential in psychopharmacology--a critical analysis with special emphasis on the antidepressant escitalopram. Eur Neuropsychopharmacol (2002) 0.92
Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study. Pharmacogenet Genomics (2013) 0.92
Impulsivity-related brain volume deficits in schizophrenia-addiction comorbidity. Brain (2010) 0.92
Neuropeptide Y and corticotropin-releasing hormone in CSF mark response to antidepressive treatment with citalopram. Int J Neuropsychopharmacol (2005) 0.92
In vitro P-glycoprotein-mediated transport of (R)-, (S)-, (R,S)-methadone, LAAM and their main metabolites. Pharmacology (2007) 0.92
Effects of grapefruit juice on the pharmacokinetics of the enantiomers of methadone. Clin Pharmacol Ther (2004) 0.91
Predictive value of readiness, importance, and confidence in ability to change drinking and smoking. BMC Public Health (2012) 0.91
Free and total plasma levels of lopinavir during pregnancy, at delivery and postpartum: implications for dosage adjustments in pregnant women. Antivir Ther (2012) 0.90
Orosomucoid (alpha1-acid glycoprotein) plasma concentration and genetic variants: effects on human immunodeficiency virus protease inhibitor clearance and cellular accumulation. Clin Pharmacol Ther (2006) 0.90
Early mobilization out of bed after ischaemic stroke reduces severe complications but not cerebral blood flow: a randomized controlled pilot trial. Clin Rehabil (2011) 0.90
Pharmacodynamic, pharmacokinetic and pharmacogenetic aspects of drugs used in the treatment of Alzheimer's disease. Clin Pharmacokinet (2013) 0.89
Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction. Int J Cardiol (2012) 0.89
Risperidone-induced symptomatic hyperprolactinaemia in adolescents. J Clin Psychopharmacol (2006) 0.89
Increased (R)-methadone plasma concentrations by quetiapine in cytochrome P450s and ABCB1 genotyped patients. J Clin Psychopharmacol (2007) 0.89
αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior. Neuropsychopharmacology (2013) 0.89
Longitudinal patterns of benzodiazepine consumption in a German cohort of methadone maintenance treatment patients. Hum Psychopharmacol (2011) 0.88
Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome. Cardiovasc Res (2008) 0.88
Opiate treatment in depression refractory to antidepressants and electroconvulsive therapy. J Clin Psychopharmacol (2008) 0.88
Selective hyper-responsiveness of the interferon system in major depressive disorders and depression induced by interferon therapy. PLoS One (2012) 0.88
Cytochrome P4503A4 metabolic activity, methadone blood concentrations, and methadone doses. Drug Alcohol Depend (2003) 0.88
Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells. PLoS Pathog (2013) 0.87
Diagnostic performance of ethyl glucuronide in hair for the investigation of alcohol drinking behavior: a comparison with traditional biomarkers. Int J Legal Med (2011) 0.87
Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy. Swiss Med Wkly (2004) 0.86
The impact of alcohol dependence on social brain function. Addict Biol (2012) 0.85
Blood pressure in relation to coffee and caffeine consumption. Curr Hypertens Rep (2014) 0.85
Auditory target processing in methadone substituted opiate addicts: the effect of nicotine in controls. BMC Psychiatry (2007) 0.85
Increased clozapine plasma concentrations and side effects induced by smoking cessation in 2 CYP1A2 genotyped patients. Ther Drug Monit (2005) 0.85
Influence of CRTC1 polymorphisms on body mass index and fat mass in psychiatric patients and the general adult population. JAMA Psychiatry (2013) 0.85
Cytochrome P450 and ABCB1 genetics: association with quetiapine and norquetiapine plasma and cerebrospinal fluid concentrations and with clinical response in patients suffering from schizophrenia. A pilot study. J Psychopharmacol (2010) 0.85
Stereoselective metabolism of citalopram in plasma and cerebrospinal fluid of depressive patients: relationship with 5-HIAA in CSF and clinical response. J Clin Psychopharmacol (2004) 0.84
Psychotropic drug-induced weight gain and other metabolic complications in a Swiss psychiatric population. J Psychiatr Res (2012) 0.84
Association of CYP3A5 genotypes with blood pressure and renal function in African families. J Hypertens (2006) 0.84
Is brief motivational intervention effective in reducing alcohol use among young men voluntarily receiving it? A randomized controlled trial. Alcohol Clin Exp Res (2011) 0.84
Stepwise evaluation of syncope: a prospective population-based controlled study. Int J Cardiol (2007) 0.84