Published in Can Med Assoc J on August 26, 1961
The association between schizophrenia and two objective tests. Can Med Assoc J (1962) 0.75
Adrenaline and adrenochrome. Biochem J (1937) 12.85
[Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system]. Klin Wochenschr (1960) 4.77
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Schizophrenia: a new approach. J Ment Sci (1952) 1.84
The concentration of adrenaline in human plasma and its relation to mental activity. J Ment Sci (1955) 1.80
Excretion of dopamine in diseases of basal ganglia. Science (1961) 1.69
Schizophrenia; a new approach. II. Result of a year's research. J Ment Sci (1954) 1.57
[Relative lack of pharmacologic action of 3-methoxy analogue of norepinephrine]. Proc Soc Exp Biol Med (1958) 0.99
Is adrenochrome present in the blood. Am J Psychiatry (1958) 0.85
Recent advances in the biochemistry of psychosis. Lancet (1960) 0.84
Methylation of the 3-OH position of catechol acids by rat liver and kidney preparations. Can J Biochem Physiol (1958) 0.83
The relationship between affect and the excretion of adrenaline, noradrenaline, and 17-hydroxycorticosteroids. J Psychosom Res (1960) 0.83
On the relationship of adrenaline and its oxidation products to schizophrenia. Am J Psychiatry (1959) 0.82
Biological activity of 3-methoxy-catecholamines. Science (1960) 0.81
Biochemical aspects of schizophrenia. J Nerv Ment Dis (1958) 0.80
On the measurement of adrenochrome in blood. Am J Psychiatry (1960) 0.80
The effects of 5-hydroxytryptophan (a serotonin precursor) in schizophrenic patients. J Ment Sci (1960) 0.79
Effects of 5-hydroxytryptophan on schizophrenia. J Ment Sci (1959) 0.79
Schizophrenia: a new approach. J Ment Sci (1959) 0.79
Physiological effects of schizophrenic body fluids. J Ment Sci (1959) 0.78
Relation between the rate of excretion of pyrocatecholamines in the urine and the outcome of electroshock therapy. Confin Neurol (1958) 0.78
Striatal amines, experimental tremor and the effect of harmaline in the monkey. Brain (1966) 1.76
Properties of purified, soluble monoamine oxidase. Can J Biochem (1966) 1.76
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies. Brain Res (1974) 1.29
Iron- and riboflavin-dependent metabolism of a monamine in the rat in vivo. Science (1971) 1.25
A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model. J Cereb Blood Flow Metab (1990) 1.20
Transport of L-tryptophan into slices of rat cerebral cortex. J Neurochem (1972) 1.17
Antidepressant action of tryptophan. Lancet (1974) 1.05
Dopa decarboxylase: substrates, coenzyme, inhibitors. Pharmacol Rev (1966) 1.04
Decreased monoamine oxidase activity in liver of iron-deficient rats. Can J Biochem (1969) 1.03
Properties of the monoamine oxidase of rat liver mitochondria. Adv Pharmacol (1968) 1.02
Decrease of cerebral serotonin and 5-hydroxyindolylacetic acid caused by (-)-alpha-methyltryptophan. J Neurochem (1970) 1.00
Serotonin synthesis rate measured in living dog brain by positron emission tomography. J Neurochem (1991) 0.99
Homovanillic acid and dihydroxyphenylacetic acid in the striatum of monkeys with brain lesions. Can J Physiol Pharmacol (1967) 0.99
Reversible effect of L-dopa on tremor and catatonia induced by alpha-methyl-p-tyrosine. Can J Physiol Pharmacol (1970) 0.99
Tryptophan catabolism by tryptophan pyrrolase in rat liver. The effect of tryptophan loads and changes in tryptophan pyrrolase activity. J Biol Chem (1975) 0.98
The effect of copper loading on the distribution of copper in rat liver cytosol. Biochem Med (1973) 0.98
Effects of aporphine and emetine alkaloids on central dopaminergic mechanisms in rats. Eur J Pharmacol (1972) 0.98
Sites of origin in the central nervous system of monoamine metabolites measured in human cerebrospinal fluid. J Neurol Neurosurg Psychiatry (1973) 0.97
Determination of UDPG and UDPGA in tissues. Anal Biochem (1967) 0.97
Liver and brain tryptophan metabolism following hydrocortisone administration to rats and gerbils. Br J Pharmacol (1975) 0.97
Importance of tryptophan pyrrolase and aromatic amino acid decarboxylase in the catabolism of tryptophan. Biochem Pharmacol (1978) 0.96
Alpha-methyltryptophan: effects on synthesis and degradation of serotonin in the brain. Neuropharmacology (1972) 0.95
Correlative neuroanatomical and neuropharmacological study of tremor and catatonia in the monkey. Neuropharmacology (1971) 0.94
Serotonin and dopamine in the extrapyramidal system. Adv Pharmacol (1968) 0.94
Effect of apomorphine on growth hormone, prolactin, luteinizing hormone and follicle-stimulating hormone levels in human serum. J Clin Endocrinol Metab (1973) 0.94
The effect of yohimbine on brain serotonin metabolism, motor behavior and body temperature of the rat. Eur J Pharmacol (1971) 0.93
Tryptophan and 5-hydroxyindoleacetic acid in human cerebrospinal fluid. J Neurochem (1974) 0.92
A new method to measure brain serotonin synthesis in vivo. II. A practical autoradiographic method tested in normal and lithium-treated rats. J Cereb Blood Flow Metab (1990) 0.91
Neurochemical bases of tremor and other disorders of movement. Can Med Assoc J (1966) 0.91
Alpha-methyltryptophan and its actions on tryptophan metabolism. Fed Proc (1971) 0.91
Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study. Acta Psychiatr Scand (1979) 0.91
Formation of respiratory 14CO2 from variously labeled forms of tryptophan-14C in intact and adrenalectomized rats. Arch Biochem Biophys (1968) 0.90
Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man. J Neurol Neurosurg Psychiatry (1974) 0.89
Relationship between rat brain and cisternal CSF tryptophan concentrations. J Neurol Neurosurg Psychiatry (1976) 0.89
Relationships between tryptophan in serum and CSF, and 5-hydroxyindoleacetic acid in CSF of man: effect of cirrhosis of liver and probenecid administration. J Neurol Neurosurg Psychiatry (1975) 0.87
Purification and properties of hog-kidney 3,4-dihydroxyphenylalanine decarboxylase. Can J Biochem (1972) 0.87
The flavin prosthetic group of purified rat liver mitochondrial monoamine oxidase. Adv Biochem Psychopharmacol (1972) 0.87
5-Hydroxyindoleacetic acid, homovanillic acid and tryptophan levels in CSF above and below a complete block of CSF flow. Psychiatr Neurol Neurochir (1974) 0.87
Deposition of copper in rat tissues--the effect of dose and duration of administration of copper sulfate. Toxicol Appl Pharmacol (1971) 0.86
Effect of yohimbine on tryptophan metabolism. J Pharmacol Exp Ther (1969) 0.86
Effect of amine precursors on the concentration of striatal dopamine and serotonin in cats with and without unilateral brain stem lesions. Brain Res (1967) 0.86
Cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid, lactic acid, and pH before and after probenecid in hepatic coma. Clin Neurol Neurosurg (1975) 0.86
Regional transport of tryptophan in rat brain. J Neurochem (1977) 0.85
Effect of brain lesions and of harmaline on the DOPA decarboxylase activity in the striatum of the cat. J Neurol Sci (1970) 0.85
The concentration of homovanillic and 5-hydroxyindoleacetic acids in ventricular and lumbar CSF. Studies in patients with extrapyramidal disorders, epilepsy, and other diseases. Neurology (1972) 0.85
The effect of theophylline on tryptophan pyrrolase in the hypophysectomized rat and some observations on the validity of tryptophan pyrrolase assays. J Biol Chem (1974) 0.84
Inhibition by albumin of tryptophan uptake by rat brain. Nature (1976) 0.84
Pharmacological and biochemical actions of the hemolytic agents acetylphenylhydrazine and phenylhydrazine on monoamine oxidase in the rat. Biochem Pharmacol (1974) 0.83
Some enzymic aspects of the production of oxidized or reduced metabolites of catecholamines and 5-hydroxytryptamine by brain tissues. J Neurochem (1974) 0.83
Apomorphine, pimozide, L-Dopa and the probenecid test in Huntington's chorea. Psychiatr Neurol Neurochir (1973) 0.82
The role of the adrenal medulla in the hypoglycemia of foetal malnutrition. Biol Neonat (1967) 0.82
Inverse relationship of heptic copper and iron concentrations in rats fed deficient diets. Can J Biochem (1968) 0.82
Influence of drugs on the temperature-lowering effect of harmaline. Eur J Pharmacol (1968) 0.82
On the origin of homovanillic acid (HVA) in the cerebrospinal fluid. J Neural Transm (1973) 0.82
(18F) Fluoro-Dopa: a unique gamma emitting substrate for Dopa decarboxylase. Experientia (1975) 0.82
On the intracerebral origin of homovanillic acid of the cerebrospinal fluid of experimental animals. Brain Res (1971) 0.81
A controlled study of tryptophan-benserazide in schizophrenia. Commun Psychopharmacol (1978) 0.81
Glucuronidation of 3-O-methylnoradrenaline, harmalol and some related compounds. Biochem J (1968) 0.81
Reserpine and the monoaminergic regulation of adrenal dopamine beta-hydroxylase activity. Neuroscience (1986) 0.81
Ontogeny of stereotyped behaviour induced by apomorphine and amphetamine in the rat. Arch Int Pharmacodyn Ther (1973) 0.81
Monoamine metabolism in human brain. Arch Gen Psychiatry (1977) 0.80
Role of protein in removal of copper from the liver. Nature (1968) 0.80
Effect of various chlorpromazine metabolites on amphetamine-induced stereotyped behaviour in the rat. Eur J Pharmacol (1972) 0.80
Putrescine metabolism and the study of diamine oxidase activity in vivo. Agents Actions (1981) 0.80
Effects of drugs on the metabolism of tryptophan. Alpha-hydrazinotryptophan and other amino acid analogs. Biochem Pharmacol (1968) 0.80
Dopaminergic function in Gilles de la Tourette's syndrome, Sydenham's chorea and torsion dystonia. Clin Neurol Neurosurg (1976) 0.80
Metabolism of alpha-methyltryptophan. Biochem Pharmacol (1965) 0.80
Parallel variation of ventricular CSF tryptophan and free serum tryptophan in man. J Neurol Neurosurg Psychiatry (1976) 0.80
Intracellular distribution of copper in the liver during chronic administration of copper sulfate to the rat. Toxicol Appl Pharmacol (1971) 0.80
Uridine nucleotides in brain. J Neurochem (1968) 0.79
Inhibition by dopamine agonists of dopamine accumulation following gamma-hydroxybutyrate treatment. Eur J Pharmacol (1975) 0.79
Biochemistry of mental depression. Can Psychiatr Assoc J (1977) 0.79
Effect of alpha-methyl-DL-tryptophan on tryptophan metabolism of Musca domestica L. Comp Biochem Physiol (1969) 0.79
Narcolepsy and idiopthic hypersomnia: biogenic amines and related compounds in CSF. Neurology (1982) 0.79
Monoamine metabolites in the CSF of epileptic patients. Neurology (1979) 0.79
Substrate-dependent activation energy of the reaction catalyzed by monoamine oxidase. Arch Biochem Biophys (1981) 0.79
Effect of apomorphine on human-growth-hormone secretion. Lancet (1972) 0.79
[Serotoninergic systems and the problem of false transmitters]. Union Med Can (1971) 0.79
O-methylation of apomorphine and the metabolic prolongation of apomorphine-induced stereotyped behaviour. Eur J Pharmacol (1973) 0.79
Activity of aldehyde dehydrogenase, aldehyde reductase, and acetylcholine esterase in striatum of rats bearing electrolytic lesions of the medial forebrain bundle. J Neurochem (1975) 0.79
Inhibition of hepatic protein synthesis by alpha-methyl-DL-tryptophan in vivo. Further studies on the glyconeogenic action of alpha-methyltryptophan. Biochemistry (1970) 0.78
Aldehyde dehydrogenase and monoamine oxidase in the striatum of cats with nigrostriatal lesions. J Neurochem (1972) 0.78
Biological model for the in vivo measurement of rate of serotonin synthesis in the brain. J Neural Transm Suppl (1990) 0.78
Acidic metabolites of dopamine and serotonin in cerebrospinal fluid. Adv Neurol (1974) 0.78
Descending spinal pathways mediating the responses of adrenal tyrosine hydroxylase and catecholamines to insulin and 2-deoxyglucose. Brain Res (1985) 0.78
Tryptophan in hepatic coma. J Neural Transm Suppl (1978) 0.78
Copper, biogenic amines, and amine oxidases. Ciba Found Symp (1980) 0.78
Essential sulfhydryl groups of rat liver monoamine oxidase. Can J Biochem (1975) 0.77
Non-mast cell histamine levels in rat tissues after histidine loading. Eur J Pharmacol (1977) 0.77
Metabolism of dihydroxyphenylalanine and tryptophan in pyridoxine-deficient rats. Ann N Y Acad Sci (1969) 0.77
Role of descending spinal pathways in the regulation of adrenal tyrosine hydroxylase. Exp Neurol (1979) 0.77
The effect of certain tranquilisers, chlorpromazine metabolites and diethyldithiocarbamate on tissue amphetamine levels in the rat. Arch Int Pharmacodyn Ther (1974) 0.77
Possible new metabolites mediating actions of L-dopa. Nature (1971) 0.77
Effect of heparin on the metabolism of putrescine in vivo. Can J Biochem (1979) 0.77
Metabolism of monoamines and diamines in hyperthyroid and hypothyroid rats. Can J Biochem (1977) 0.77
Concentration of homovanillic acid in the ventricular fluid of patients with Parkinson's disease and other dyskinesias. Neurology (1970) 0.77
The influence of alpha-methyltryptophan and some tryptophan metabolites on hepatic glycogenesis. Biochemistry (1967) 0.77
Conversion of 14C-dopamine to cardiac 14C-noradrenaline in the copper-deficient rat. Eur J Pharmacol (1967) 0.77
Studies on cyclic AMP in different compartments of cerebrospinal fluid. J Neurol Neurosurg Psychiatry (1976) 0.77
Action of inhibitors on monoamine and diamine metabolism in the rat. Can J Biochem (1977) 0.77