PubRank

Nicholas Topley

Author PubWeight™ 69.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Morphologic changes in the peritoneal membrane of patients with renal disease. J Am Soc Nephrol 2002 3.33
2 Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat Med 2005 2.06
3 The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane. Kidney Int 2004 1.91
4 Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus. J Rheumatol 2009 1.84
5 Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J Clin Invest 2003 1.69
6 IL-6 regulates neutrophil trafficking during acute inflammation via STAT3. J Immunol 2008 1.69
7 Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130. J Immunol 2003 1.68
8 IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. Proc Natl Acad Sci U S A 2005 1.66
9 The natural course of peritoneal membrane biology during peritoneal dialysis. Kidney Int Suppl 2003 1.58
10 The pathophysiology of the peritoneal membrane. J Am Soc Nephrol 2010 1.47
11 Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. PLoS Pathog 2011 1.46
12 Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. J Biol Chem 2005 1.45
13 12/15-Lipoxygenase regulates the inflammatory response to bacterial products in vivo. J Immunol 2008 1.38
14 Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol 2010 1.36
15 A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. PLoS Pathog 2009 1.35
16 Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. J Immunol 2009 1.35
17 Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering. J Immunol 2009 1.22
18 Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. J Biol Chem 2009 1.18
19 Independent effects of systemic and peritoneal inflammation on peritoneal dialysis survival. J Am Soc Nephrol 2013 1.18
20 Differential regulation of neutrophil-activating chemokines by IL-6 and its soluble receptor isoforms. J Immunol 2004 1.14
21 Pathogen-specific local immune fingerprints diagnose bacterial infection in peritoneal dialysis patients. J Am Soc Nephrol 2013 1.09
22 Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis Rheum 2006 1.07
23 Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 2010 1.02
24 Effects of conventional and new peritoneal dialysis fluids on leukocyte recruitment in the rat peritoneal membrane. J Am Soc Nephrol 2003 1.01
25 Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J 2010 1.01
26 Enhanced neutrophil migratory activity following major blunt trauma. Injury 2005 1.01
27 TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. Eur J Immunol 2011 1.00
28 Interferon-gamma protects against the development of structural damage in experimental arthritis by regulating polymorphonuclear neutrophil influx into diseased joints. Arthritis Rheum 2007 0.98
29 Glucose degradation products (GDP) retard remesothelialization independently of D-glucose concentration. Kidney Int 2003 0.97
30 Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol 2002 0.97
31 Peritoneal dialysis: changes to the structure of the peritoneal membrane and potential for biocompatible solutions. Kidney Int Suppl 2003 0.96
32 Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. J Biol Chem 2006 0.96
33 Increased neutrophil migratory activity after major trauma: a factor in the etiology of acute respiratory distress syndrome? Crit Care Med 2002 0.95
34 Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis. J Am Soc Nephrol 2009 0.94
35 Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent. Kidney Int 2003 0.93
36 Identification and analysis of the promoter region of the human hyaluronan synthase 2 gene. J Biol Chem 2004 0.92
37 Intraperitoneal IL-6 signaling in incident patients treated with icodextrin and glucose bicarbonate/lactate-based peritoneal dialysis solutions. Perit Dial Int 2012 0.91
38 Interferon-gamma inhibits interleukin-1beta-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis. Arthritis Res Ther 2010 0.88
39 Can artifact mimic the pathology of the peritoneal mesothelium? Perit Dial Int 2003 0.88
40 Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors. Nephrol Dial Transplant 2011 0.87
41 Clinical indices of in vivo biocompatibility: the role of ex vivo cell function studies and effluent markers in peritoneal dialysis patients. Kidney Int Suppl 2003 0.86
42 Morphological and functional changes in the dialysed peritoneal cavity: impact of more biocompatible solutions. Nephrol Dial Transplant 2002 0.86
43 Viral IL-6 blocks neutrophil infiltration during acute inflammation. J Immunol 2005 0.86
44 Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation. J Immunol 2008 0.85
45 The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers. Int J Biochem Cell Biol 2003 0.84
46 Dialysate interleukin-6 predicts increasing peritoneal solute transport rate in incident peritoneal dialysis patients. BMC Nephrol 2014 0.84
47 Peritoneal membrane transport: driving under the influence. Perit Dial Int 2006 0.84
48 Nitric oxide synthase isoforms play distinct roles during acute peritonitis. Nephrol Dial Transplant 2009 0.82
49 How can genetic advances impact on experimental models of encapsulating peritoneal sclerosis? Perit Dial Int 2008 0.82
50 Piece by piece: solving the puzzle of peritoneal fibrosis. Perit Dial Int 2008 0.81
51 Neutrophil priming for elastase release in adult blunt trauma patients. J Trauma 2006 0.80
52 Alteration of polymorphonuclear neutrophil surface receptor expression and migratory activity after isolation: comparison of whole blood and isolated PMN preparations from normal and postfracture trauma patients. J Trauma 2006 0.80
53 Inhibition of nitric oxide synthase reverses permeability changes in a mouse model of acute peritonitis. Perit Dial Int 2005 0.79
54 Targeting the TLR co-receptor CD14 with TLR2-derived peptides modulates immune responses to pathogens. Sci Transl Med 2013 0.79
55 Receptor-interacting protein-2 deficiency delays macrophage migration and increases intracellular infection during peritoneal dialysis-associated peritonitis. Am J Nephrol 2008 0.78
56 Continuous dialysis with bicarbonate/lactate-buffered peritoneal dialysis fluids results in a long-term improvement in ex vivo peritoneal macrophage function. J Am Soc Nephrol 2002 0.78
57 Proteomics and peritoneal dialysis: early days but clear potential. Nephrol Dial Transplant 2010 0.78
58 Chemiluminescence: comparison of whole blood with isolated polymorphonuclear leukocytes after major trauma. J Trauma 2004 0.77
59 Switching on EMT in the peritoneal membrane: considering the evidence. Nephrol Dial Transplant 2010 0.77
60 Suppression of pro-inflammatory T-cell responses by human mesothelial cells. Nephrol Dial Transplant 2013 0.76
61 Peritoneal fibrosis is mouse strain dependent. Nephrol Dial Transplant 2012 0.76
62 Altering peritoneal membrane function: removing the GAG? Nephrol Dial Transplant 2009 0.76
63 Neutrophil activation and renal scarring. Kidney Int 2005 0.75
64 Now you see them, now you don't. Perit Dial Int 2004 0.75
65 Encapsulating peritoneal sclerosis: time to act. Perit Dial Int 2006 0.75
66 Peritoneal infection and inflammation. Mediators Inflamm 2012 0.75
67 What are renal defensins defending? Nephron Exp Nephrol 2003 0.75
68 The in vitro biocompatibility performance of a 25 mmol/L bicarbonate/10 mmol/L lactate-buffered peritoneal dialysis fluid. Kidney Int Suppl 2003 0.75