|
1
|
Propagation of tau pathology in a model of early Alzheimer's disease.
|
Neuron
|
2012
|
6.23
|
|
2
|
Caspase activation precedes and leads to tangles.
|
Nature
|
2010
|
3.24
|
|
3
|
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.
|
Neuron
|
2010
|
2.68
|
|
4
|
A systems approach to prion disease.
|
Mol Syst Biol
|
2009
|
2.49
|
|
5
|
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.
|
Am J Pathol
|
2006
|
2.47
|
|
6
|
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein.
|
Proc Natl Acad Sci U S A
|
2008
|
2.27
|
|
7
|
In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons.
|
J Neurosci
|
2008
|
1.77
|
|
8
|
NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.
|
J Neurosci
|
2005
|
1.68
|
|
9
|
Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain.
|
Am J Pathol
|
2011
|
1.30
|
|
10
|
Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy.
|
J Neuropathol Exp Neurol
|
2009
|
1.19
|
|
11
|
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
|
Proc Natl Acad Sci U S A
|
2011
|
1.19
|
|
12
|
Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency.
|
Proc Natl Acad Sci U S A
|
2012
|
1.11
|
|
13
|
Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model.
|
J Neuropathol Exp Neurol
|
2011
|
1.10
|
|
14
|
Prion infection of mouse neurospheres.
|
Proc Natl Acad Sci U S A
|
2006
|
1.01
|
|
15
|
Synaptic alterations in the rTg4510 mouse model of tauopathy.
|
J Comp Neurol
|
2013
|
0.99
|
|
16
|
Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease.
|
J Neurosci
|
2013
|
0.96
|
|
17
|
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
|
Acta Neuropathol
|
2013
|
0.96
|
|
18
|
Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
|
PLoS Pathog
|
2011
|
0.96
|
|
19
|
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
|
Acta Neuropathol Commun
|
2015
|
0.94
|
|
20
|
The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases.
|
Database (Oxford)
|
2009
|
0.92
|
|
21
|
Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression.
|
Hum Mol Genet
|
2004
|
0.90
|
|
22
|
Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia.
|
Front Pharmacol
|
2012
|
0.84
|
|
23
|
Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy.
|
PLoS One
|
2013
|
0.81
|
|
24
|
Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
|
J Comp Neurol
|
2013
|
0.81
|
|
25
|
Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau.
|
PLoS One
|
2012
|
0.79
|
|
26
|
Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease.
|
PLoS One
|
2013
|
0.79
|