1
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Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
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Nat Genet
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2011
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4.04
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2
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Blood pressure and hypertension are associated with 7 loci in the Japanese population.
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Circulation
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2010
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1.66
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3
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Inhibitor for advanced glycation end products formation attenuates hypertension and oxidative damage in genetic hypertensive rats.
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J Hypertens
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2002
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1.52
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4
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Genome-wide searches for blood pressure quantitative trait loci in the stroke-prone spontaneously hypertensive rat of a Japanese colony.
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J Hypertens
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2003
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1.38
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5
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Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population.
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Circ J
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2011
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1.37
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6
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Genome-wide association study of coronary artery disease in the Japanese.
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Eur J Hum Genet
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2011
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1.32
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7
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Effect of a gamma-aminobutyric acid-enriched dairy product on the blood pressure of spontaneously hypertensive and normotensive Wistar-Kyoto rats.
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Br J Nutr
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2004
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1.21
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8
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Nutritional variation and cardiovascular risk factors in Tanzania--rural-urban difference.
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S Afr Med J
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2003
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1.16
|
9
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Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment.
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Hypertension
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2004
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1.09
|
10
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Black and green tea polyphenols attenuate blood pressure increases in stroke-prone spontaneously hypertensive rats.
|
J Nutr
|
2004
|
1.08
|
11
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Serum lipid effects of a monounsaturated (palmitoleic) fatty acid-rich diet based on macadamia nuts in healthy, young Japanese women.
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Clin Exp Pharmacol Physiol
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2004
|
1.05
|
12
|
Antioxidant nutrients and hypoxia/ischemia brain injury in rodents.
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Toxicology
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2003
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1.05
|
13
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Gene-environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population.
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Hypertens Res
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2009
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1.02
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14
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Inverse relationship between urinary markers of animal protein intake and blood pressure in Chinese: results from the WHO Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study.
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Int J Epidemiol
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2002
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1.01
|
15
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Obesity, emerging risk in China: trend of increasing prevalence of obesity and its association with hypertension and hypercholesterolaemia among the Chinese.
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Clin Exp Pharmacol Physiol
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2004
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1.01
|
16
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Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells.
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Hypertens Res
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2003
|
0.95
|
17
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Beneficial effects of soybean isoflavone supplementation on bone metabolism and serum lipids in postmenopausal japanese women: a four-week study.
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J Am Coll Nutr
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2002
|
0.95
|
18
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Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats.
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Hypertens Res
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2002
|
0.95
|
19
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Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.
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PLoS One
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2012
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0.94
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20
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Prevalence of dementia in the older Japanese-Brazilian population.
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Psychiatry Clin Neurosci
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2002
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0.93
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21
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Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes.
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Glia
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2003
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0.93
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22
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Effects of dietary intake of soy protein and isoflavones on cardiovascular disease risk factors in high risk, middle-aged men in Scotland.
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J Am Coll Nutr
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2004
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0.91
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23
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Cyanidin-3-glucoside regulates phosphorylation of endothelial nitric oxide synthase.
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FEBS Lett
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2004
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0.90
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24
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Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr.
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Environ Health Prev Med
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2011
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0.90
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25
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Caffeic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II in stroke-prone spontaneously hypertensive rats.
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Hypertens Res
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2005
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0.89
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26
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Hypoxia-induced changes in tight junction permeability of brain capillary endothelial cells are associated with IL-1beta and nitric oxide.
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Neurobiol Dis
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2004
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0.88
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27
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Prevalence of obesity and dyslipidemia in middle-aged men and women in Tanzania, Africa: relationship with resting energy expenditure and dietary factors.
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J Nutr Sci Vitaminol (Tokyo)
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2002
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0.88
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28
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Physical activity and cardiovascular disease risk factors among young and middle-aged men in urban Mwanza, Tanzania.
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Pan Afr Med J
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2012
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0.87
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29
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Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways.
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Phytother Res
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2009
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0.87
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30
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Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract suppresses multiple angiogenesis-related endothelial cell functions and tumor angiogenesis.
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Mol Nutr Food Res
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2011
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0.86
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31
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Epidemiological evidence of the association between dietary protein intake and blood pressure: a meta-analysis of published data.
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Hypertens Res
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2002
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0.85
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32
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Evaluation of genetic loci influencing adult height in the Japanese population.
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J Hum Genet
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2009
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0.85
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33
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C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase.
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Mol Endocrinol
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2006
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0.85
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34
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Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat.
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Hypertens Res
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2005
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0.85
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35
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Genetic impact on uric acid concentration and hyperuricemia in the Japanese population.
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J Atheroscler Thromb
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2012
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0.84
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36
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Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.
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PLoS One
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2012
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0.84
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37
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Atherogenic dyslipidemia and altered hepatic gene expression in SHRSP.Z-Leprfa/IzmDmcr rats.
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Int J Mol Med
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2009
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0.84
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38
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Role of the renal nerves in gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats.
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Eur J Pharmacol
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2005
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0.84
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39
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Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo.
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Cancer Sci
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2010
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0.84
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40
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Effects of Ginkgo biloba extract (EGb 761) on cerebral thrombosis and blood pressure in stroke-prone spontaneously hypertensive rats.
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Clin Exp Pharmacol Physiol
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2002
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0.84
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41
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Deterioration of traditional dietary custom increases the risk of lifestyle-related diseases in young male Africans.
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J Biomed Sci
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2010
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0.83
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42
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Proposition of a feasible protocol to evaluate salt sensitivity in a population-based setting.
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Hypertens Res
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2002
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0.83
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43
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Effects of the herbal medicine composition "Saiko-ka-ryukotsu-borei-To" on the function of endothelial progenitor cells in hypertensive rats.
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Phytomedicine
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2012
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0.83
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44
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Cardiovascular remodeling and metabolic abnormalities in SHRSP.Z-Lepr(fa)/IzmDmcr rats as a new model of metabolic syndrome.
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Hypertens Res
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2008
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0.82
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45
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Supplementation of elderly Japanese men and women with fucoidan from seaweed increases immune responses to seasonal influenza vaccination.
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J Nutr
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2013
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0.82
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46
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Green tea polyphenols down-regulate caveolin-1 expression via ERK1/2 and p38MAPK in endothelial cells.
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J Nutr Biochem
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2009
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0.82
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47
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Inhibitory effect of polyphenol cyanidin on TNF-alpha-induced apoptosis through multiple signaling pathways in endothelial cells.
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Atherosclerosis
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2006
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0.82
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48
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High-fat-cholesterol diet mainly induced necrosis in fibrotic steatohepatitis rat by suppressing caspase activity.
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Life Sci
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2013
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0.82
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49
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Isolation of a chromosome 1 region affecting blood pressure and vascular disease traits in the stroke-prone rat model.
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Hypertension
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2003
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0.82
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50
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Differential regulation of glial cell line-derived neurotrophic factor (GDNF) mRNA expression during hypoxia and reoxygenation in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
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Glia
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2002
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0.81
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51
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Resting heart rate in relation to blood pressure: results from the World Health Organization-Cardiovascular Disease and Alimentary Comparison study.
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Int J Cardiol
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2009
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0.81
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52
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Soy isoflavone tablets reduce osteoporosis risk factors and obesity in middle-aged Japanese women.
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Clin Exp Pharmacol Physiol
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2004
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0.81
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53
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Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats.
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Dig Dis Sci
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2013
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0.81
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54
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Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.
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Clin Exp Pharmacol Physiol
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2013
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0.81
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55
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Taurine in 24-h Urine Samples Is Inversely Related to Cardiovascular Risks of Middle Aged Subjects in 50 Populations of the World.
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Adv Exp Med Biol
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2015
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0.81
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56
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Low birth weight as cardiometabolic risk in Japanese high school girls.
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J Am Coll Nutr
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2012
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0.80
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57
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A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model.
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Dig Dis Sci
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2014
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0.80
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58
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The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model.
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Life Sci
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2012
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0.80
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59
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Caffeic acid phenethyl ester suppresses oxidative stress in 3T3-L1 adipocytes.
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J Asian Nat Prod Res
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2013
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0.80
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60
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Phosphorylated endothelial NOS Ser1177 via the PI3K/Akt pathway is depressed in the brain of stroke-prone spontaneously hypertensive rat.
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J Stroke Cerebrovasc Dis
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2010
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0.80
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61
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New chromone derivative terminalianone from African plant Terminalia brownii Fresen (Combretaceae) in Tanzania.
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J Asian Nat Prod Res
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2011
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0.80
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62
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Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway.
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Genes Nutr
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2012
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0.79
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63
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Comprehensive QTL analysis of serum cholesterol levels before and after a high-cholesterol diet in SHRSP.
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Physiol Genomics
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2007
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0.79
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64
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Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat.
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Environ Health Prev Med
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2012
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0.79
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65
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Pharmacological studies of alcohol susceptibility and brain monoamine function in stroke-prone spontaneously hypertensive rats (SHRSP) and stroke-resistant spontaneously hypertensive rats (SHRSR).
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Tohoku J Exp Med
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2003
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0.78
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66
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Antithrombotic effect of taurine in healthy Japanese people may be related to an increased endogenous thrombolytic activity.
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Thromb Res
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2012
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0.78
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67
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Effects of docosahexaenoic Acid supplementation on blood pressure, heart rate, and serum lipids in Scottish men with hypertension and hypercholesterolemia.
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Int J Hypertens
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2011
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0.78
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68
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Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
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Clin Exp Pharmacol Physiol
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2004
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0.78
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69
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Hypertension, periodontal disease, and potassium intake in nonsmoking, nondrinker african women on no medication.
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Int J Hypertens
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2011
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0.78
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70
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Flax oil-mediated activation of PPAR-γ correlates with reduction of hepatic lipid accumulation in obese spontaneously hypertensive/NDmcr-cp rats, a model of the metabolic syndrome.
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Br J Nutr
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2010
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0.78
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71
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Adenosine induces expression of glial cell line-derived neurotrophic factor (GDNF) in primary rat astrocytes.
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Neurosci Res
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2007
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0.78
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72
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Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese.
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Asia Pac J Clin Nutr
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2012
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0.78
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73
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Effects of cooking using multi-ply cookware on absorption of potassium and vitamins: a randomized double-blind placebo control study.
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Int J Food Sci Nutr
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2012
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0.77
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74
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Soy isoflavones improve bone metabolism in postmenopausal Japanese women.
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Clin Exp Pharmacol Physiol
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2004
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0.77
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75
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Relationship of sodium and magnesium intakes to hypertension proven by 24-hour urianalysis in a South Indian population.
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J Clin Hypertens (Greenwich)
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2014
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0.77
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76
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Mitochondrial HMG-CoA synthase partially contributes to antioxidant protection in the kidney of stroke-prone spontaneously hypertensive rats.
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Nutrition
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2010
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0.77
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77
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Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.
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Hypertens Res
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2004
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0.77
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78
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Palatinose-blended sugar compared with sucrose: different effects on insulin sensitivity after 12 weeks supplementation in sedentary adults.
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Int J Food Sci Nutr
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2010
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0.77
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79
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The role of cytochrome p-450 in salt-sensitive stroke in stroke-prone spontaneously hypertensive rats.
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Hypertens Res
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2008
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80
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Downregulation of Rac1 activation by caffeic acid in aortic smooth muscle cells.
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Life Sci
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2005
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0.76
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81
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First direct comparison of platelet reactivity and thrombolytic status between Japanese and Western volunteers: possible relationship to the "Japanese paradox".
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Int J Cardiol
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2010
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0.76
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82
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Delivery may affect arterial elasticity in women.
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Circ J
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2009
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0.76
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83
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Comparative studies on 24-hour urinary excretion in Japanese and Chinese adults and children--need for nutritional education.
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Adv Exp Med Biol
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2009
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84
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Effects of voluntary exercise on cerebral thrombosis and endothelial function in spontaneously hypertensive rats (SHRSP/Izm).
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Clin Exp Pharmacol Physiol
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2004
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85
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Possible association of high urinary magnesium and taurine to creatinine ratios with metabolic syndrome risk reduction in Australian aboriginals.
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Cardiol Res Pract
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2011
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0.75
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86
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Evaluation of the atrial natriuretic peptide gene in stroke.
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Atherosclerosis
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2002
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87
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Taurine in morning spot urine for the useful assessment of dietary seafood intake in Japanese children and adolescents.
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J Biomed Sci
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2010
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88
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Peripheral gene expression profile of mechanical hyperalgesia induced by repeated cold stress in SHRSP5/Dmcr rats.
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J Physiol Sci
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2015
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89
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Nitric oxide reduces astrocytic lactate production and induces neuronal vulnerability in stroke-prone spontaneously hypertensive rats.
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Glia
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OS 03-01 HIGHER SALT INTAKE ATTENUATES NOCTURNAL DIPPING IN BLOOD PRESSURE AND HEART RATE.
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J Hypertens
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2016
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Change in the protein level of mevalonate pyrophosphate decarboxylase in tissues of mouse by pravastatin.
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Biol Pharm Bull
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2003
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92
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OS 03-01 HIGHER SALT INTAKE ATTENUATES NOCTURNAL DIPPING IN BLOOD PRESSURE AND HEART RATE.
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J Hypertens
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2016
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93
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Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor {beta} and expression of glycodelin in human endometrial epithelial cells.
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J Endocrinol
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2008
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0.75
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94
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Comparison of subcellular distribution of mevalonate pyrophosphate decarboxylase between stroke-prone spontaneously hypertensive rat and Wistar Kyoto rat.
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Biol Pharm Bull
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2002
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Subcellular distribution of mouse mevalonate pyrophosphate decarboxylase.
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Biol Pharm Bull
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[Animal models for metabolic syndrome].
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Nihon Rinsho
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Correction: Soy and fish as features of the Japanese diet and cardiovascular disease risks.
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PLoS One
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2017
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98
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Nutritional prevention on hypertension, cerebral hemodynamics and thrombosis in stroke-prone spontaneously hypertensive rats.
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Cell Mol Neurobiol
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2004
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Effect of a soybean product on serum lipid levels in female university students.
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Clin Exp Pharmacol Physiol
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2004
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100
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Peroxisome proliferative drugs do not induce an increase of rat mevalonate pyrophosphate decarboxylase.
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Biol Pharm Bull
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2003
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101
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Purification and characterization of mouse mevalonate pyrophosphate decarboxylase.
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Biol Pharm Bull
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2002
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102
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Estimation of hydroxyl radicals based on the salicylate trapping method in hippocampus of stroke-prone spontaneously hypertensive rats (SHRSP) during transient ischemia and recirculation.
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Adv Exp Med Biol
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2003
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103
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High susceptibility of obese hypertensive SHRSP.Z-Lepr(fa) /IzmDmcr rats to lipid deposition in the mesenteric artery.
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Clin Exp Pharmacol Physiol
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2010
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104
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Probucol decreases mevalonate pyrophosphate decarboxylase in the rat liver.
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Biol Pharm Bull
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[A rat model of metabolic syndrome].
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