PubRank

Jean-Philippe Stephan

Author PubWeight™ 28.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology 2004 4.25
2 A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell 2011 2.14
3 A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. Am J Pathol 2002 2.02
4 Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Invest 2009 1.89
5 PlGF blockade does not inhibit angiogenesis during primary tumor growth. Cell 2010 1.75
6 Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin. J Virol 2012 1.50
7 Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Res 2009 1.41
8 TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer. Mol Cell 2012 1.34
9 Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). J Med Chem 2012 1.27
10 An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer. Cancer Res 2012 1.23
11 Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma. Blood 2007 1.11
12 Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4. MAbs 2011 1.06
13 High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate. Br J Haematol 2007 1.03
14 Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies. Clin Cancer Res 2013 1.02
15 Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake. Mol Cancer Ther 2008 0.98
16 Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans. MAbs 2012 0.95
17 Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold. J Med Chem 2009 0.88
18 Ultrasensitive detection of cellular protein interactions using bioluminescence resonance energy transfer quantum dot-based nanoprobes. J Cell Biochem 2012 0.80
19 Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma. Cancer Chemother Pharmacol 2011 0.78
20 Application of a new wall-less plate technology to complex multistep cell-based investigations using suspension cells. Blood 2012 0.77
21 Nucleic acid capture assay, a new method for direct quantitation of nucleic acids. Nucleic Acids Res 2003 0.75