PubRank

Nicholas M Luscombe

Author PubWeight™ 112.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A census of human transcription factors: function, expression and evolution. Nat Rev Genet 2009 9.19
2 The transcriptional activity of human Chromosome 22. Genes Dev 2003 6.82
3 iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution. Nat Struct Mol Biol 2010 5.98
4 Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs. Genome Res 2004 5.26
5 DNA-binding specificities of human transcription factors. Cell 2013 5.14
6 Structure and evolution of transcriptional regulatory networks. Curr Opin Struct Biol 2004 4.48
7 Distribution of NF-kappaB-binding sites across human chromosome 22. Proc Natl Acad Sci U S A 2003 3.89
8 Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Res 2010 3.46
9 GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proc Natl Acad Sci U S A 2002 3.41
10 Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 2002 3.27
11 Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila. Cell 2008 3.18
12 Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22. Genome Res 2002 2.89
13 Protein-RNA interactions: new genomic technologies and perspectives. Nat Rev Genet 2012 2.80
14 Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters. Science 2012 2.75
15 Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements. Cell 2013 2.67
16 Gene loops enhance transcriptional directionality. Science 2012 2.50
17 Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. J Bacteriol 2008 2.47
18 iCLIP predicts the dual splicing effects of TIA-RNA interactions. PLoS Biol 2010 2.39
19 Genomic analysis of gene expression relationships in transcriptional regulatory networks. Trends Genet 2003 2.38
20 Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast. J Mol Biol 2006 2.36
21 CREB binds to multiple loci on human chromosome 22. Mol Cell Biol 2004 2.28
22 Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. PLoS Genet 2010 1.94
23 iCLIP--transcriptome-wide mapping of protein-RNA interactions with individual nucleotide resolution. J Vis Exp 2011 1.80
24 Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli. Nucleic Acids Res 2010 1.71
25 The nonspecific lethal complex is a transcriptional regulator in Drosophila. Mol Cell 2010 1.68
26 Evidence of non-random mutation rates suggests an evolutionary risk management strategy. Nature 2012 1.56
27 Prediction of regulatory networks: genome-wide identification of transcription factor targets from gene expression data. Bioinformatics 2003 1.55
28 Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes. Nucleic Acids Res 2002 1.40
29 Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targets. Nucleic Acids Res 2010 1.35
30 Transcriptional regulatory networks in bacteria: from input signals to output responses. Curr Opin Microbiol 2006 1.30
31 A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast. Genome Res 2011 1.23
32 Genomics of DNA cytosine methylation in Escherichia coli reveals its role in stationary phase transcription. Nat Commun 2012 1.19
33 Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity. Nucleic Acids Res 2010 1.14
34 Principles of transcriptional regulation and evolution of the metabolic system in E. coli. Genome Res 2008 1.14
35 Non-random mutation: the evolution of targeted hypermutation and hypomutation. Bioessays 2012 1.09
36 The NSL complex regulates housekeeping genes in Drosophila. PLoS Genet 2012 1.08
37 Genomic analysis of DNA binding and gene regulation by homologous nucleoid-associated proteins IHF and HU in Escherichia coli K12. Nucleic Acids Res 2011 1.05
38 The MOF chromobarrel domain controls genome-wide H4K16 acetylation and spreading of the MSL complex. Dev Cell 2012 1.02
39 Extrapolating traditional DNA microarray statistics to tiling and protein microarray technologies. Methods Enzymol 2006 0.99
40 Cellular resolution models for even skipped regulation in the entire Drosophila embryo. Elife 2013 0.98
41 Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast. Nucleic Acids Res 2014 0.92
42 Transcriptomics and adaptive genomics of the asymptomatic bacteriuria Escherichia coli strain 83972. Mol Genet Genomics 2008 0.88
43 The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1. Mol Cell Proteomics 2011 0.85
44 SpeCond: a method to detect condition-specific gene expression. Genome Biol 2011 0.85
45 Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med 2011 0.84
46 Response to Comments on "Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters". Science 2013 0.83
47 m:Explorer: multinomial regression models reveal positive and negative regulators of longevity in yeast quiescence. Genome Biol 2012 0.81
48 Know your limits: assumptions, constraints and interpretation in systems biology. Biochim Biophys Acta 2009 0.80
49 Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements. Genome Res 2013 0.80
50 How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genome. Methods Mol Biol 2012 0.79
51 Large-scale nuclear architecture and transcriptional control. Subcell Biochem 2011 0.78
52 Comparative genomics suggests differential deployment of linear and branched signaling across bacteria. Mol Biosyst 2011 0.76
53 An overview of prokaryotic transcription factors : a summary of function and occurrence in bacterial genomes. Subcell Biochem 2011 0.76
54 Structural genomics: a new era for pharmaceutical research. Genome Biol 2002 0.75
55 Transcriptional networking. Genome Biol 2005 0.75