| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
Nat Genet
|
2009
|
14.86
|
|
2
|
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
|
Nat Genet
|
2011
|
9.23
|
|
3
|
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
|
Gastroenterology
|
2007
|
2.32
|
|
4
|
Late-life depression, mild cognitive impairment, and dementia: possible continuum?
|
Am J Geriatr Psychiatry
|
2010
|
2.22
|
|
5
|
An association study between epicardial fat thickness and cognitive impairment in the elderly.
|
Am J Physiol Heart Circ Physiol
|
2014
|
2.06
|
|
6
|
The prevalence of diarrhea and its association with drug use in elderly outpatients: a multicenter study.
|
Am J Gastroenterol
|
2008
|
1.64
|
|
7
|
Development and validation of a multidimensional prognostic index for one-year mortality from comprehensive geriatric assessment in hospitalized older patients.
|
Rejuvenation Res
|
2008
|
1.60
|
|
8
|
Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumors.
|
Clin Cancer Res
|
2004
|
1.55
|
|
9
|
Prevalence, clinical features and avoidability of adverse drug reactions as cause of admission to a geriatric unit: a prospective study of 1756 patients.
|
Drug Saf
|
2008
|
1.31
|
|
10
|
Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease.
|
Ageing Res Rev
|
2010
|
1.30
|
|
11
|
Metabolic syndrome and cognitive impairment: current epidemiology and possible underlying mechanisms.
|
J Alzheimers Dis
|
2010
|
1.23
|
|
12
|
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.
|
J Alzheimers Dis
|
2010
|
1.19
|
|
13
|
Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies.
|
Immunotherapy
|
2012
|
1.18
|
|
14
|
The Multidimensional Prognostic Index (MPI), based on a comprehensive geriatric assessment predicts short- and long-term mortality in hospitalized older patients with dementia.
|
J Alzheimers Dis
|
2009
|
1.16
|
|
15
|
Alcohol consumption in mild cognitive impairment and dementia: harmful or neuroprotective?
|
Int J Geriatr Psychiatry
|
2012
|
1.08
|
|
16
|
Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms.
|
J Alzheimers Dis
|
2010
|
1.06
|
|
17
|
Glycerophospholipids and glycerophospholipid-derived lipid mediators: a complex meshwork in Alzheimer's disease pathology.
|
Prog Lipid Res
|
2011
|
1.05
|
|
18
|
Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?
|
Expert Opin Investig Drugs
|
2011
|
1.04
|
|
19
|
Mutations of the D310 mitochondrial mononucleotide repeat in primary tumors and cytological specimens.
|
Cancer Lett
|
2003
|
1.04
|
|
20
|
Diet and Alzheimer's disease risk factors or prevention: the current evidence.
|
Expert Rev Neurother
|
2011
|
1.03
|
|
21
|
A combined analytical approach reveals novel EXT1/2 gene mutations in a large cohort of Italian multiple osteochondromas patients.
|
Genes Chromosomes Cancer
|
2007
|
1.01
|
|
22
|
Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations.
|
Neurobiol Aging
|
2011
|
1.00
|
|
23
|
Alcohol drinking, cognitive functions in older age, predementia, and dementia syndromes.
|
J Alzheimers Dis
|
2009
|
0.98
|
|
24
|
Solanezumab for the treatment of mild-to-moderate Alzheimer's disease.
|
Expert Rev Clin Immunol
|
2012
|
0.97
|
|
25
|
Usefulness of the comprehensive geriatric assessment in older patients with upper gastrointestinal bleeding: a two-year follow-up study.
|
Dig Dis
|
2007
|
0.97
|
|
26
|
Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease.
|
Expert Rev Neurother
|
2014
|
0.97
|
|
27
|
Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome?
|
J Alzheimers Dis
|
2010
|
0.96
|
|
28
|
REVIEW: γ-Secretase inhibitors for the treatment of Alzheimer's disease: The current state.
|
CNS Neurosci Ther
|
2010
|
0.96
|
|
29
|
Clinical features of reflux esophagitis in older people: a study of 840 consecutive patients.
|
J Am Geriatr Soc
|
2006
|
0.94
|
|
30
|
Anti-β-amyloid immunotherapy for Alzheimer's disease: focus on bapineuzumab.
|
Curr Alzheimer Res
|
2011
|
0.93
|
|
31
|
Angiotensin-converting enzyme inhibitors and incidence of mild cognitive impairment. The Italian Longitudinal Study on Aging.
|
Age (Dordr)
|
2011
|
0.92
|
|
32
|
Frailty syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Aging.
|
Alzheimers Dement
|
2012
|
0.92
|
|
33
|
Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment.
|
J Alzheimers Dis
|
2010
|
0.91
|
|
34
|
Lipoproteins, vascular-related genetic factors, and human longevity.
|
Rejuvenation Res
|
2007
|
0.90
|
|
35
|
Neuropsychiatric symptoms and functional status in Alzheimer's disease and vascular dementia patients.
|
Curr Alzheimer Res
|
2012
|
0.89
|
|
36
|
APOE epsilon 2/epsilon 4 genotype a risk factor for primary progressive aphasia in women.
|
Arch Neurol
|
2009
|
0.88
|
|
37
|
Polymorphisms in glutathione S-transferase omega-1 gene and increased risk of sporadic Alzheimer disease.
|
Rejuvenation Res
|
2010
|
0.87
|
|
38
|
Apolipoprotein E genotypes in hospitalized elderly patients with vascular dementia.
|
Dement Geriatr Cogn Disord
|
2007
|
0.87
|
|
39
|
FOXP2, APOE, and PRNP: new modulators in primary progressive aphasia.
|
J Alzheimers Dis
|
2012
|
0.86
|
|
40
|
Apolipoprotein E genotypes and neuropsychiatric symptoms and syndromes in late-onset Alzheimer's disease.
|
Ageing Res Rev
|
2011
|
0.85
|
|
41
|
Effectiveness of the frequency rhythmic electrical modulation system for the treatment of chronic and painful venous leg ulcers in older adults.
|
Rejuvenation Res
|
2012
|
0.85
|
|
42
|
Frailty syndrome and all-cause mortality in demented patients: the Italian Longitudinal Study on Aging.
|
Age (Dordr)
|
2011
|
0.85
|
|
43
|
The complex interaction between APOE promoter and AD: an Italian case-control study.
|
Eur J Hum Genet
|
2009
|
0.85
|
|
44
|
Beyond the neurotransmitter-focused approach in treating Alzheimer's disease: drugs targeting beta-amyloid and tau protein.
|
Aging Clin Exp Res
|
2009
|
0.85
|
|
45
|
Higher total cholesterol, cognitive decline, and dementia.
|
Neurobiol Aging
|
2008
|
0.85
|
|
46
|
Current epidemiological approaches to the metabolic-cognitive syndrome.
|
J Alzheimers Dis
|
2012
|
0.83
|
|
47
|
Differential modulation of Ku70/80 DNA-binding activity in a patient with multiple basal cell carcinomas.
|
J Invest Dermatol
|
2003
|
0.83
|
|
48
|
Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease.
|
Expert Opin Drug Discov
|
2011
|
0.83
|
|
49
|
The APOE polymorphism in Alzheimer's disease patients with neuropsychiatric symptoms and syndromes.
|
Int J Geriatr Psychiatry
|
2010
|
0.82
|
|
50
|
Apoe epsilon2-epsilon4 genotype is a possible risk factor for primary progressive aphasia.
|
Ann Neurol
|
2006
|
0.81
|
|
51
|
Bapineuzumab: anti-β-amyloid monoclonal antibodies for the treatment of Alzheimer's disease.
|
Immunotherapy
|
2010
|
0.81
|
|
52
|
Neuropsychiatric Symptoms, Endophenotypes, and Syndromes in Late-Onset Alzheimer's Disease: Focus on APOE Gene.
|
Int J Alzheimers Dis
|
2011
|
0.81
|
|
53
|
Apolipoprotein E, dementia, and human longevity.
|
J Am Geriatr Soc
|
2009
|
0.81
|
|
54
|
DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor.
|
World J Gastroenterol
|
2005
|
0.81
|
|
55
|
Monoclonal antibodies against β-amyloid (Aβ) for the treatment of Alzheimer's disease: the Aβ target at a crossroads.
|
Expert Opin Biol Ther
|
2011
|
0.81
|
|
56
|
Undercoding of Alzheimer's disease and related dementias in hospitalized elderly patients in Italy.
|
Am J Alzheimers Dis Other Demen
|
2005
|
0.80
|
|
57
|
Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease.
|
J Neurol Sci
|
2006
|
0.80
|
|
58
|
Diet, cholesterol metabolism, and Alzheimer's disease: Apolipoprotein E as a possible link?
|
J Am Geriatr Soc
|
2006
|
0.80
|
|
59
|
LRP-1 variation is not associated with risk of Alzheimer's disease.
|
Int J Mol Epidemiol Genet
|
2010
|
0.80
|
|
60
|
Apolipoprotein E genotypes in mild cognitive impairment subtypes.
|
J Am Geriatr Soc
|
2006
|
0.80
|
|
61
|
Survival in Alzheimer's disease is shorter in women carrying heterozygosity at codon 129 of the PRNP gene and no APOE epsilon 4 allele.
|
Dement Geriatr Cogn Disord
|
2008
|
0.80
|
|
62
|
Short arm of chromosome 11 and sporadic Alzheimer's disease: catalase and cathepsin D gene polymorphisms.
|
Neurosci Lett
|
2007
|
0.79
|
|
63
|
Comparison of four proton pump inhibitors for the short-term treatment of esophagitis in elderly patients.
|
World J Gastroenterol
|
2007
|
0.79
|
|
64
|
Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model.
|
Biochem Biophys Res Commun
|
2008
|
0.78
|
|
65
|
Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: a genetic association analysis.
|
Age (Dordr)
|
2011
|
0.78
|
|
66
|
Dietary patterns and protection against Alzheimer disease and cognitive decline.
|
Arch Neurol
|
2010
|
0.78
|
|
67
|
Interleukin 6-174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2009
|
0.78
|
|
68
|
Psychotic symptoms in Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: evidence for an association.
|
J Alzheimers Dis
|
2009
|
0.77
|
|
69
|
Genetic variation in MME in relation to neprilysin protein and enzyme activity, Aβ levels, and Alzheimer's disease risk.
|
Int J Mol Epidemiol Genet
|
2012
|
0.77
|
|
70
|
Plasma lipid disturbances and cognitive decline.
|
J Am Geriatr Soc
|
2010
|
0.77
|
|
71
|
ApoE gene delivery inhibits severe hypercholesterolemia in newborn ApoE-KO mice.
|
Biochem Biophys Res Commun
|
2007
|
0.77
|
|
72
|
Treatment of late-life major depressive disorder with selective serotonin reuptake inhibitors improves the multidimensional prognostic index.
|
J Clin Psychopharmacol
|
2012
|
0.77
|
|
73
|
Pharmacogenetics in geriatric medicine: challenges and opportunities for clinical practice.
|
Curr Drug Metab
|
2011
|
0.77
|
|
74
|
Differences in allele frequencies of ACE I/D polymorphism between Northern and Southern Europe at different ages.
|
Atherosclerosis
|
2006
|
0.77
|
|
75
|
Association of apolipoprotein E and angiotensin converting enzyme gene polymorphisms with the multidimensional impairment in older patients.
|
Rejuvenation Res
|
2009
|
0.76
|
|
76
|
Dietary unsaturated fatty acids and risk of mild cognitive impairment.
|
J Alzheimers Dis
|
2010
|
0.76
|
|
77
|
Frailty, disability and physical exercise in the aging process and in chronic kidney disease.
|
Kidney Blood Press Res
|
2014
|
0.75
|
|
78
|
Apolipoprotein E-related all-cause mortality in hospitalized elderly patients.
|
Age (Dordr)
|
2010
|
0.75
|
|
79
|
Peripheral antioxidant markers in mild cognitive impairment and its progression to dementia.
|
J Alzheimers Dis
|
2010
|
0.75
|
|
80
|
Is Extracorporeal Shockwave Therapy Combined With Isokinetic Exercise More Effective Than Extracorporeal Shockwave Therapy Alone for Subacromial Impingement Syndrome? A Randomized Clinical Trial.
|
J Orthop Sports Phys Ther
|
2016
|
0.75
|
|
81
|
Possible predictors of vascular cognitive impairment-no dementia.
|
J Am Geriatr Soc
|
2009
|
0.75
|
|
82
|
Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs.
|
Clin Lab
|
2011
|
0.75
|
|
83
|
Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease.
|
Neurobiol Aging
|
2008
|
0.75
|
|
84
|
Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection.
|
Eur J Epidemiol
|
2007
|
0.75
|
|
85
|
Phytochemicals in the Treatment of Alzheimer's Disease: A Systematic Review.
|
Curr Drug Targets
|
2016
|
0.75
|
|
86
|
Plasma levels of n-3 polyunsaturated fatty acids and cognitive decline: possible role of depressive symptoms and apolipoprotein E genotyping.
|
J Am Geriatr Soc
|
2010
|
0.75
|
|
87
|
[Forkhead-box-O1 locus and metabolic markers in the elderly: an association study].
|
Rev Esp Geriatr Gerontol
|
2012
|
0.75
|
|
88
|
Pharmacogenetics in Neurodegenerative Diseases: Implications for Clinical Trials.
|
Front Neurol Neurosci
|
2016
|
0.75
|