An LYPSL late domain in the gag protein contributes to the efficient release and replication of Rous sarcoma virus.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 2903267)

Published in J Virol on April 14, 2010

Authors

Kari A Dilley1, Devon Gregory, Marc C Johnson, Volker M Vogt

Author Affiliations

1: Department of Molecular Biology and Genetics, Biotech Bldg., Cornell University, Ithaca, NY 14853, USA.

Articles cited by this

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell (2001) 12.00

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release. Proc Natl Acad Sci U S A (1991) 10.05

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat Med (2001) 8.38

AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell (2003) 6.69

The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol (2004) 6.31

Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. Science (2007) 6.13

An assembly domain of the Rous sarcoma virus Gag protein required late in budding. J Virol (1994) 5.87

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc Natl Acad Sci U S A (2001) 5.83

A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding. Proc Natl Acad Sci U S A (2000) 5.30

Positionally independent and exchangeable late budding functions of the Rous sarcoma virus and human immunodeficiency virus Gag proteins. J Virol (1995) 4.92

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. Proc Natl Acad Sci U S A (2003) 4.21

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function. Proc Natl Acad Sci U S A (2002) 4.14

Late budding domains and host proteins in enveloped virus release. Virology (2006) 4.11

Equine infectious anemia virus utilizes a YXXL motif within the late assembly domain of the Gag p9 protein. J Virol (1997) 4.08

Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain. J Virol (1996) 3.97

Retrovirus budding. Virus Res (2004) 3.66

Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding. Cell (2007) 3.06

Overlapping motifs (PTAP and PPEY) within the Ebola virus VP40 protein function independently as late budding domains: involvement of host proteins TSG101 and VPS-4. J Virol (2003) 3.05

Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells. Proc Natl Acad Sci U S A (2001) 3.04

Infectivity of Moloney murine leukemia virus defective in late assembly events is restored by late assembly domains of other retroviruses. J Virol (2000) 2.98

Imaging the biogenesis of individual HIV-1 virions in live cells. Nature (2008) 2.92

The late domain of human immunodeficiency virus type 1 p6 promotes virus release in a cell type-dependent manner. J Virol (2002) 2.66

Visualization of retrovirus budding with correlated light and electron microscopy. Proc Natl Acad Sci U S A (2005) 2.41

HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway. J Cell Biol (2004) 2.34

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release. Proc Natl Acad Sci U S A (2008) 2.33

Structural basis for endosomal targeting by the Bro1 domain. Dev Cell (2005) 2.28

The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release. J Virol (2003) 2.19

Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1. Nat Rev Microbiol (2007) 2.08

Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site. J Virol (2007) 1.93

Context-dependent effects of L domains and ubiquitination on viral budding. J Virol (2004) 1.92

Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus. J Virol (2005) 1.88

Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing. Virology (1991) 1.84

Retroviral gene delivery. Methods Cell Biol (1997) 1.82

PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected]. J Virol (2003) 1.80

Intronic sequences and 3' splice sites control Rous sarcoma virus RNA splicing. J Virol (1992) 1.79

Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV. Nat Struct Mol Biol (2007) 1.76

Structural basis for viral late-domain binding to Alix. Nat Struct Mol Biol (2007) 1.69

Functional replacement and positional dependence of homologous and heterologous L domains in equine infectious anemia virus replication. J Virol (2002) 1.60

The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral budding. PLoS Pathog (2009) 1.55

Human immunodeficiency virus type 1 Gag engages the Bro1 domain of ALIX/AIP1 through the nucleocapsid. J Virol (2007) 1.48

An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains. J Biol Chem (2006) 1.44

The ESCRT pathway and HIV-1 budding. Biochem Soc Trans (2009) 1.32

Assembly of the murine leukemia virus is directed towards sites of cell-cell contact. PLoS Biol (2009) 1.32

Role of Nedd4 and ubiquitination of Rous sarcoma virus Gag in budding of virus-like particles from cells. J Virol (2004) 1.27

A bipartite late-budding domain in human immunodeficiency virus type 1. J Virol (2003) 1.25

The cell biology of HIV-1 and other retroviruses. Retrovirology (2006) 1.21

Both the PPPY and PTAP motifs are involved in human T-cell leukemia virus type 1 particle release. J Virol (2004) 1.17

Functional role of Alix in HIV-1 replication. Virology (2009) 1.16

The functionally exchangeable L domains in RSV and HIV-1 Gag direct particle release through pathways linked by Tsg101. Traffic (2005) 1.16

Divergent Bro1 domains share the capacity to bind human immunodeficiency virus type 1 nucleocapsid and to enhance virus-like particle production. J Virol (2009) 1.05

Rous sarcoma virus negative regulator of splicing selectively suppresses SRC mRNA splicing and promotes polyadenylation. Virology (2002) 0.97

Heterologous late-domain sequences have various abilities to promote budding of human immunodeficiency virus type 1. J Virol (2005) 0.97

The negative regulator of splicing element of Rous sarcoma virus promotes polyadenylation. J Virol (2006) 0.92

Deletion of a Cys-His motif from the Alpharetrovirus nucleocapsid domain reveals late domain mutant-like budding defects. Virology (2006) 0.91

Refined study of the interaction between HIV-1 p6 late domain and ALIX. Retrovirology (2008) 0.89

Basal budding and replication of the murine leukemia virus are independent of the gag L domains. J Virol (2008) 0.81

Functional hierarchy of two L domains in porcine endogenous retrovirus (PERV) that influence release and infectivity. Virology (2008) 0.79

Transgene expression facilitated by the v-src splice acceptor can impair replication kinetics and lead to genomic instability of Rous sarcoma virus-based vectors. J Virol (2007) 0.77

Articles by these authors

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe (2008) 9.27

Tetherin inhibits HIV-1 release by directly tethering virions to cells. Cell (2009) 5.06

The stoichiometry of Gag protein in HIV-1. Nat Struct Mol Biol (2004) 4.91

Plasma membrane is the site of productive HIV-1 particle assembly. PLoS Biol (2006) 4.43

Nef proteins from simian immunodeficiency viruses are tetherin antagonists. Cell Host Microbe (2009) 4.11

Visualization of retrovirus budding with correlated light and electron microscopy. Proc Natl Acad Sci U S A (2005) 2.41

Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis. Cell Host Microbe (2008) 1.91

Direct measurement of Gag-Gag interaction during retrovirus assembly with FRET and fluorescence correlation spectroscopy. J Cell Biol (2003) 1.70

Nucleic acid-independent retrovirus assembly can be driven by dimerization. J Virol (2002) 1.66

Rous sarcoma virus Gag protein-oligonucleotide interaction suggests a critical role for protein dimer formation in assembly. J Virol (2002) 1.56

The retroviral capsid domain dictates virion size, morphology, and coassembly of gag into virus-like particles. J Virol (2005) 1.52

Ubiquitin-dependent virus particle budding without viral protein ubiquitination. Proc Natl Acad Sci U S A (2007) 1.51

Cryo-electron microscopy reveals conserved and divergent features of gag packing in immature particles of Rous sarcoma virus and human immunodeficiency virus. J Mol Biol (2005) 1.47

Electrostatic interactions drive membrane association of the human immunodeficiency virus type 1 Gag MA domain. J Virol (2007) 1.42

Biochemical characterization of rous sarcoma virus MA protein interaction with membranes. J Virol (2005) 1.27

HIV-1 Gag protein can sense the cholesterol and acyl chain environment in model membranes. Proc Natl Acad Sci U S A (2012) 1.24

Nucleic acid binding-induced Gag dimerization in the assembly of Rous sarcoma virus particles in vitro. J Virol (2004) 1.19

Dimeric rous sarcoma virus capsid protein structure relevant to immature Gag assembly. J Mol Biol (2004) 1.17

Foreign glycoproteins can be actively recruited to virus assembly sites during pseudotyping. J Virol (2009) 1.09

A molecular switch required for retrovirus assembly participates in the hexagonal immature lattice. EMBO J (2008) 1.09

Conserved and variable features of Gag structure and arrangement in immature retrovirus particles. J Virol (2010) 1.09

The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production. J Virol (2006) 1.05

Clathrin facilitates the morphogenesis of retrovirus particles. PLoS Pathog (2011) 1.05

Neural cell adhesion molecule (NCAM) marks adult myogenic cells committed to differentiation. Exp Cell Res (2008) 1.03

Rous sarcoma virus gag has no specific requirement for phosphatidylinositol-(4,5)-bisphosphate for plasma membrane association in vivo or for liposome interaction in vitro. J Virol (2011) 1.02

Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding. J Virol (2008) 1.00

The NV gene of snakehead rhabdovirus (SHRV) is not required for pathogenesis, and a heterologous glycoprotein can be incorporated into the SHRV envelope. J Virol (2004) 0.95

Effect of multimerization on membrane association of Rous sarcoma virus and HIV-1 matrix domain proteins. J Virol (2013) 0.93

The C-terminal half of TSG101 blocks Rous sarcoma virus budding and sequesters Gag into unique nonendosomal structures. J Virol (2005) 0.92

Solution structure of the Rous sarcoma virus nucleocapsid protein: muPsi RNA packaging signal complex. J Mol Biol (2006) 0.90

Domain swapping and retroviral assembly. Mol Cell (2005) 0.90

Higher-order structure of the Rous sarcoma virus SP assembly domain. J Virol (2014) 0.89

Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio. Dev Comp Immunol (2004) 0.88

Two distinct mechanisms regulate recruitment of murine leukemia virus envelope protein to retroviral assembly sites. Virology (2010) 0.87

Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing. Mol Ther (2012) 0.86

Knocking down gene function with an RNA aptamer expressed as part of an intron. Nucleic Acids Res (2010) 0.86

Characterization of the protease of a fish retrovirus, walleye dermal sarcoma virus. J Virol (2002) 0.86

NMR relaxation studies of an RNA-binding segment of the rous sarcoma virus gag polyprotein in free and bound states: a model for autoinhibition of assembly. Biochemistry (2010) 0.85

Pseudotyping incompatibility between HIV-1 and gibbon ape leukemia virus Env is modulated by Vpu. J Virol (2009) 0.84

Retrovirus glycoprotein functionality requires proper alignment of the ectodomain and the membrane-proximal cytoplasmic tail. J Virol (2013) 0.82

Blocking HIV-1 virus assembly. Nat Struct Mol Biol (2005) 0.82

CRM1-dependent trafficking of retroviral Gag proteins revisited. J Virol (2012) 0.82

Multiple Gag domains contribute to selective recruitment of murine leukemia virus (MLV) Env to MLV virions. J Virol (2012) 0.81

Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch. Protein Sci (2007) 0.81

Vpu downmodulates two distinct targets, tetherin and gibbon ape leukemia virus envelope, through shared features in the Vpu cytoplasmic tail. PLoS One (2012) 0.80

Walleye dermal sarcoma virus reverse transcriptase is temperature sensitive. J Gen Virol (2002) 0.80

Sequences in gibbon ape leukemia virus envelope that confer sensitivity to HIV-1 accessory protein Vpu. J Virol (2011) 0.79

Recombination can lead to spurious results in retroviral transduction with dually fluorescent reporter genes. J Virol (2013) 0.78

Functional complementation of a model target to study Vpu sensitivity. PLoS One (2013) 0.75