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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Werner syndrome protein is a DNA helicase. Nat Genet 1997 4.03
2 Activity staining of nucleolytic enzymes after sodium dodecyl sulfate-polyacrylamide gel electrophoresis: use of aqueous isopropanol to remove detergent from gels. Anal Biochem 1982 2.50
3 An RNA polymerase mutant with reduced accuracy of chain elongation. Biochemistry 1986 1.75
4 A functional GTP-binding motif is necessary for antiviral activity of Mx proteins. J Virol 1993 1.64
5 Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix. J Biol Chem 2000 1.58
6 Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy. Arch Dermatol 1999 1.44
7 The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. Clin Cancer Res 2002 1.37
8 Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas. Clin Cancer Res 2001 1.36
9 O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clin Cancer Res 1999 1.34
10 Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin. Clin Cancer Res 1996 1.27
11 Detection of enzymatic activities in sodium dodecyl sulfate-polyacrylamide gels: DNA polymerases as model enzymes. Anal Biochem 1983 1.26
12 O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines. Clin Cancer Res 2005 1.23
13 O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems. Biochim Biophys Acta 2012 1.22
14 Quantitative estimation of attenuation in ultrasound video images: correlation with histology in diffuse liver disease. Invest Radiol 2000 1.22
15 O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics. Cancer Res 1998 1.13
16 Ribonucleases of human serum, urine, cerebrospinal fluid, and leukocytes. Activity staining following electrophoresis in sodium dodecyl sulfate-polyacrylamide gels. Biochemistry 1981 1.03
17 Posttraumatic stress disorder in a community group of former prisoners of war: a normative response to severe trauma. Am J Psychiatry 1997 1.02
18 Mx proteins: GTPases involved in the interferon-induced antiviral state. Ciba Found Symp 1993 1.01
19 Human glioma cell sensitivity to the sequence-specific alkylating agent methyl-lexitropsin. Clin Cancer Res 2007 1.01
20 Lack of the DNA repair protein O6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors. Proc Natl Acad Sci U S A 1996 0.94
21 The to and fro sign: the hallmark of pseudoaneurysm. Isr Med Assoc J 2001 0.93
22 HIV-infected patients and treatment outcomes: an equivalence study of community-located, primary care-based HIV treatment vs. hospital-based specialty care in the Bronx, New York. AIDS Care 2010 0.93
23 Comorbidity and course of psychiatric disorders in a community sample of former prisoners of war. Am J Psychiatry 1998 0.92
24 Contribution of O6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines. Mol Carcinog 1995 0.90
25 Multiple ribonucleases of human urine. Biochemistry 1981 0.89
26 Repair of 3-methyladenine and abasic sites by base excision repair mediates glioblastoma resistance to temozolomide. Front Oncol 2012 0.89
27 Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression. Mol Cancer Ther 2010 0.88
28 Apurinic endonuclease activity in adult gliomas and time to tumor progression after alkylating agent-based chemotherapy and after radiotherapy. Clin Cancer Res 2004 0.88
29 Solubility and fluoride release in ionomers and compomers. Quintessence Int 1999 0.88
30 Mirror movements in hemiparesis. Confin Neurol 1974 0.87
31 Acute, severe, central and peripheral nervous system combined demyelination. Pediatr Neurol 1989 0.87
32 O6-methylguanine-DNA methyltransferase deficiency in developing brain: implications for brain tumorigenesis. DNA Repair (Amst) 2007 0.84
33 Dielectric Resonator for Ka-Band Pulsed EPR Measurements at Cryogenic Temperatures: Probehead Construction and Applications. Appl Magn Reson 2012 0.83
34 Ribonuclease U 4 from Ustilago sphaerogena. Purification and physical properties. Biochemistry 1972 0.83
35 Electrically elicited blink reflex in children. Arch Phys Med Rehabil 1983 0.82
36 Microsatellite instability is infrequent in sporadic adult gliomas. Oncol Res 1998 0.81
37 The electrophysiologic pattern of development of muscular fatigue in muscular dystrophy. Electromyogr Clin Neurophysiol 1980 0.81
38 Relationship between the human T-lymphotropic virus type 1 infection and clinical manifestations of tegumentary leishmaniasis in the Colombian Pacific Coast. Mem Inst Oswaldo Cruz 1999 0.81
39 Increased serum levels of C-terminal parathyroid hormone-related protein in different diseases associated with HTLV-1 infection. Leukemia 1994 0.81
40 Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival. DNA Repair (Amst) 2008 0.80
41 Geographic independence of HTLV-I and HTLV-II foci in the Andes highland, the Atlantic coast, and the Orinoco of Colombia. AIDS Res Hum Retroviruses 1994 0.80
42 Apurinic/apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma. Int J Cancer 2011 0.80
43 The size of active motor units in the initiation and maintenance of an isometric contraction carried out to fatigue. Electromyogr Clin Neurophysiol 1980 0.80
44 Differences in glycosylation pattern of human secretory ribonucleases. Biochem J 1988 0.79
45 Human body fluid ribonucleases: detection, interrelationships and significance. Nucleic Acids Symp Ser 1981 0.78
46 Phylogenetic study of ten new HTLV-I strains from the Americas. AIDS Res Hum Retroviruses 1994 0.78
47 Effect of exercise of the lower limbs on the non-exercised biceps brachii muscle. Am J Phys Med 1984 0.78
48 Ethnic segregation of HTLV-I and HTLV-II carriers among South American native Indians. Int J Cancer 1995 0.77
49 Ribonucleases of human cerebrospinal fluid: detection of altered glycosylation relative to their serum counterparts. Biochemistry 1982 0.77
50 Infective dermatitis in Colombia. Lancet 1995 0.77
51 Estimation of spin-echo relaxation time. J Magn Reson 2013 0.77
52 Electromyographic investigation of the superficial sphincter ani muscle (SSAM) in spinal cord injury. Electromyogr Clin Neurophysiol 1975 0.77
53 Differential activity staining: its use in characterization of guanylyl-specific ribonuclease in the genus Ustilago. Proc Natl Acad Sci U S A 1975 0.76
54 Perfusion culture promotes differentiation of oral keratinocytes in vitro. J Physiol Pharmacol 2009 0.76
55 Recurrent inhibition in spastic hemiplegia. Electromyogr Clin Neurophysiol 1985 0.76
56 Comparison of the electrophysiological pattern of fatigue between athletes required to perform explosive and endurance sports. Electromyogr Clin Neurophysiol 1990 0.76
57 Electrophysiological pattern of development of muscle fatigue in patients undergoing dialysis. Electromyogr Clin Neurophysiol 1987 0.76
58 The elderly: abused or abusers? Can Med Assoc J 1982 0.75
59 HTLV-II detection in an Amerindian family in Colombian southern Andean region. J Acquir Immune Defic Syndr Hum Retrovirol 1995 0.75
60 [Electrophysiological testing in peripheral nerve injuries]. Harefuah 1976 0.75
61 [Reflex sympathetic dystrophy syndrome]. Harefuah 1986 0.75
62 [The syndrome of multiple pain in human body]. Harefuah 1979 0.75
63 [Pseudomyotonia with cervical osteoarthrotic changes]. Harefuah 1978 0.75
64 Electrophysiological assessment of the tongue and the conduction time of the hypoglossal nerve. Electromyogr Clin Neurophysiol 1987 0.75
65 Ribonuclease U 4 . Novel phosphotransferases catalyzing exonucleolytic degradation of ribonucleic acid. Biochemistry 1972 0.75
66 A comparative study of the efficacy of ACTH4-9 analog, methylphenidate, and placebo on attention deficit disorder with hyperkinesis. J Clin Psychopharmacol 1983 0.75
67 Dermabrasion of lesions of adenoma sebaceum. J Dermatol Surg Oncol 1981 0.75
68 [Shoulder-hand syndrome in patients with hemiplegia]. Harefuah 1974 0.75
69 Recovery after muscular fatigue in hemiparesis. Am J Phys Med 1981 0.75
70 Lundh meal: a single non-invasive challenge test for evaluation of exocrine and endocrine pancreatic function in cystic fibrosis patients. Int J Clin Lab Res 1999 0.75
71 Efficacy of ACTH 4-9 analog, methylphenidate, and placebo on attention deficit disorder with hyperkinesis. Prog Neuropsychopharmacol Biol Psychiatry 1984 0.75
72 Distribution of HLA and haplotypes of Colombian and Jamaican black populations. Tissue Antigens 1995 0.75
73 Electrophysiological pattern of development of fatigue during isometric contraction in sportsmen. Electromyogr Clin Neurophysiol 1988 0.75
74 Effects of artificially induced ischemia (AII) on the electrophysiological pattern of muscular fatigue in healthy humans. Electromyogr Clin Neurophysiol 1980 0.75
75 [Mortality in spinal cord injuries]. Harefuah 1977 0.75
76 Mammographic evolution of fat necrosis of the breast. Breast J 2002 0.75
77 [The tendon test of the tibial nerve in Hansen's disease]. Hansenol Int 1983 0.75
78 Nemaline myopathy and a mitochondrial neuromuscular disorder in one family. Neuropediatrics 1981 0.75
79 The electrophysiological pattern of sustained muscular contraction in ischemic heart disease (IHD). Electromyogr Clin Neurophysiol 1984 0.75