Published in Vaccine on April 29, 2010
Population genomics of post-vaccine changes in pneumococcal epidemiology. Nat Genet (2013) 2.63
Clonal replacement among 19A Streptococcus pneumoniae in Massachusetts, prior to 13 valent conjugate vaccination. Vaccine (2011) 1.22
Expression of the type 1 pneumococcal pilus is bistable and negatively regulated by the structural component RrgA. Infect Immun (2011) 1.00
Toll-like receptor (TLR) 2 mediates inflammatory responses to oligomerized RrgA pneumococcal pilus type 1 protein. J Biol Chem (2012) 0.99
Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum. PLoS Comput Biol (2012) 0.97
Prevalence and clonal distribution of pcpA, psrP and Pilus-1 among pediatric isolates of Streptococcus pneumoniae. PLoS One (2012) 0.93
Nasopharyngeal colonization elicits antibody responses to staphylococcal and pneumococcal proteins that are not associated with a reduced risk of subsequent carriage. Infect Immun (2012) 0.89
Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae. PLoS Pathog (2015) 0.88
Panel 6: Vaccines. Otolaryngol Head Neck Surg (2013) 0.83
Expression of the Streptococcus pneumoniae pilus-1 undergoes on and off switching during colonization in mice. Sci Rep (2013) 0.82
An epigenetic switch mediates bistable expression of the type 1 pilus genes in Streptococcus pneumoniae. J Bacteriol (2011) 0.81
Invasive and noninvasive Streptococcus pneumoniae capsule and surface protein diversity following the use of a conjugate vaccine. Clin Vaccine Immunol (2013) 0.81
Population Structure of Streptococcus pneumoniae Causing Invasive Disease in Adults in Portugal before PCV13 Availability for Adults: 2008-2011. PLoS One (2016) 0.80
Emergence of Multidrug-resistant Pneumococcal Serotype 35B among U.S. Children. J Clin Microbiol (2016) 0.79
Prevalence of pilus-encoding islets and clonality of pneumococcal isolates from children with acute otitis media. Eur J Clin Microbiol Infect Dis (2011) 0.79
Staphylococcus aureus and Streptococcus pneumoniae interaction and response to pneumococcal vaccination: Myth or reality? Hum Vaccin Immunother (2016) 0.79
Piliation of invasive Streptococcus pneumoniae isolates in the era before pneumococcal conjugate vaccine introduction in Malawi. Clin Vaccine Immunol (2013) 0.76
Diverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening. Proc Natl Acad Sci U S A (2017) 0.76
A Serine-Threonine Kinase (StkP) Regulates Expression of the Pneumococcal Pilus and Modulates Bacterial Adherence to Human Epithelial and Endothelial Cells In Vitro. PLoS One (2015) 0.76
Panel 5: Microbiology and immunology panel. Otolaryngol Head Neck Surg (2013) 0.76
Genetic diversity of the Pneumococcal CbpA: Implications for next-generation vaccine development. Hum Vaccin Immunother (2015) 0.75
The Pneumococcal Type 1 Pilus Genes Are Thermoregulated and Are Repressed by a Member of the Snf2 Protein Family. J Bacteriol (2017) 0.75
Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis (2004) 9.73
Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. N Engl J Med (2006) 7.68
Estimates of world-wide distribution of child deaths from acute respiratory infections. Lancet Infect Dis (2002) 6.73
Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004. J Infect Dis (2007) 6.45
Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis. Lancet (2007) 5.50
A pneumococcal pilus influences virulence and host inflammatory responses. Proc Natl Acad Sci U S A (2006) 4.40
Direct and indirect effects of routine vaccination of children with 7-valent pneumococcal conjugate vaccine on incidence of invasive pneumococcal disease--United States, 1998-2003. MMWR Morb Mortal Wkly Rep (2005) 4.39
Effect of pneumococcal conjugate vaccine on pneumococcal meningitis. N Engl J Med (2009) 4.38
Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004. Pediatrics (2005) 3.42
Continued impact of pneumococcal conjugate vaccine on carriage in young children. Pediatrics (2009) 3.32
Invasive pneumococcal disease in children 5 years after conjugate vaccine introduction--eight states, 1998-2005. MMWR Morb Mortal Wkly Rep (2008) 3.03
Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household members. Clin Infect Dis (2008) 2.72
Indirect effect of conjugate vaccine on adult carriage of Streptococcus pneumoniae: an explanation of trends in invasive pneumococcal disease. J Infect Dis (2006) 2.30
RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet. Infect Immun (2006) 2.18
Impact of the pneumococcal conjugate vaccine on serotype distribution and antimicrobial resistance of invasive Streptococcus pneumoniae isolates in Dallas, TX, children from 1999 through 2005. Pediatr Infect Dis J (2007) 2.15
Streptococcus pneumoniae pilus subunits protect mice against lethal challenge. Infect Immun (2006) 1.74
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells. J Bacteriol (2008) 1.72
Changing characteristics of invasive pneumococcal disease in Metropolitan Atlanta, Georgia, after introduction of a 7-valent pneumococcal conjugate vaccine. Clin Infect Dis (2007) 1.68
Clonal success of piliated penicillin nonsusceptible pneumococci. Proc Natl Acad Sci U S A (2007) 1.64
Pneumonia hospitalizations among young children before and after introduction of pneumococcal conjugate vaccine--United States, 1997-2006. MMWR Morb Mortal Wkly Rep (2009) 1.54
Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence. J Clin Microbiol (2007) 1.51
Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related. J Infect Dis (2008) 1.49
Changes in serotypes and antimicrobial susceptibility of invasive Streptococcus pneumoniae strains in Cleveland: a quarter century of experience. J Clin Microbiol (2008) 1.45
Antibiotic-resistant Streptococcus pneumoniae in the heptavalent pneumococcal conjugate vaccine era: predictors of carriage in a multicommunity sample. Pediatrics (2003) 1.37
The presence of the pilus locus is a clonal property among pneumococcal invasive isolates. BMC Microbiol (2008) 1.36
Molecular characterization of equine isolates of Streptococcus pneumoniae: natural disruption of genes encoding the virulence factors pneumolysin and autolysin. Infect Immun (1999) 1.35
Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine. Clin Microbiol Infect (2008) 1.28
The pneumococcal pilus predicts the absence of Staphylococcus aureus co-colonization in pneumococcal carriers. Clin Infect Dis (2009) 1.23
Pneumococcal meningitis in the era of pneumococcal conjugate vaccine implementation. Eur J Clin Microbiol Infect Dis (2007) 1.15
Measuring immune selection. Parasitology (2002) 1.13
Pandemic potential of a strain of influenza A (H1N1): early findings. Science (2009) 26.24
eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J Bacteriol (2004) 17.92
Transmissibility of 1918 pandemic influenza. Nature (2004) 16.14
Rapid pneumococcal evolution in response to clinical interventions. Science (2011) 9.09
Seasonality of antibiotic-resistant streptococcus pneumoniae that causes acute otitis media: a clue for an antibiotic-restriction policy? J Infect Dis (2008) 7.76
A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet (2005) 7.64
Serotype replacement in disease after pneumococcal vaccination. Lancet (2011) 7.14
Whole-genome genotyping with the single-base extension assay. Nat Methods (2006) 6.66
The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol (2007) 6.19
Public health interventions and epidemic intensity during the 1918 influenza pandemic. Proc Natl Acad Sci U S A (2007) 5.90
The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis. PLoS Med (2009) 5.86
Estimates of the prevalence of pandemic (H1N1) 2009, United States, April-July 2009. Emerg Infect Dis (2009) 5.56
Absolute humidity and the seasonal onset of influenza in the continental United States. PLoS Biol (2010) 5.43
Prescription drug use in pregnancy. Am J Obstet Gynecol (2004) 4.92
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nat Genet (2011) 4.81
Maternal age and other predictors of newborn blood pressure. J Pediatr (2004) 4.78
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci U S A (2003) 4.56
Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nat Genet (2011) 4.19
Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung. Cancer Res (2006) 4.11
Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog (2008) 4.05
Estimation of the reproductive number and the serial interval in early phase of the 2009 influenza A/H1N1 pandemic in the USA. Influenza Other Respir Viruses (2009) 4.02
Emergence of 19A as virulent and multidrug resistant Pneumococcus in Massachusetts following universal immunization of infants with pneumococcal conjugate vaccine. Pediatr Infect Dis J (2007) 3.99
Recombination and the nature of bacterial speciation. Science (2007) 3.98
Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr (2007) 3.89
Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults. Gastroenterology (2008) 3.79
Inhaled nitric oxide in premature infants with the respiratory distress syndrome. N Engl J Med (2003) 3.78
Legislative mandates for use of active surveillance cultures to screen for methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci: position statement from the Joint SHEA and APIC Task Force. Infect Control Hosp Epidemiol (2007) 3.57
Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States. Nat Med (2003) 3.54
Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals. Proc Natl Acad Sci U S A (2004) 3.46
Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004. Pediatrics (2005) 3.42
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. Proc Natl Acad Sci U S A (2012) 3.42
Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis (2012) 3.41
Continued impact of pneumococcal conjugate vaccine on carriage in young children. Pediatrics (2009) 3.32
CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization. Proc Natl Acad Sci U S A (2005) 3.30
Variation in HIV-1 set-point viral load: epidemiological analysis and an evolutionary hypothesis. Proc Natl Acad Sci U S A (2007) 3.29
Viral shedding and clinical illness in naturally acquired influenza virus infections. J Infect Dis (2010) 3.29
Weather-based prediction of Plasmodium falciparum malaria in epidemic-prone regions of Ethiopia I. Patterns of lagged weather effects reflect biological mechanisms. Malar J (2004) 3.07
Control-group selection importance in studies of antimicrobial resistance: examples applied to Pseudomonas aeruginosa, Enterococci, and Escherichia coli. Clin Infect Dis (2002) 2.99
Timing of solid food introduction and risk of obesity in preschool-aged children. Pediatrics (2011) 2.99
Predictors of change in physical activity during and after pregnancy: Project Viva. Am J Prev Med (2007) 2.98
Breast-feeding and risk for childhood obesity: does maternal diabetes or obesity status matter? Diabetes Care (2006) 2.93
Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA (2007) 2.91
Maternal gestational weight gain and offspring weight in adolescence. Obstet Gynecol (2008) 2.90
Pandemic flu: we are not prepared. MedGenMed (2005) 2.89
The bacterial species challenge: making sense of genetic and ecological diversity. Science (2009) 2.88
Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo. PLoS Biol (2006) 2.81
Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Nat Genet (2013) 2.80
Racial/ethnic differences in early-life risk factors for childhood obesity. Pediatrics (2010) 2.73
Differential effects of pneumococcal vaccines against serotypes 6A and 6C. J Infect Dis (2008) 2.70
Pneumococcal capsular polysaccharide structure predicts serotype prevalence. PLoS Pathog (2009) 2.69
Improving the estimation of influenza-related mortality over a seasonal baseline. Epidemiology (2012) 2.68
Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis (2012) 2.67
Population genomics of post-vaccine changes in pneumococcal epidemiology. Nat Genet (2013) 2.63
Short sleep duration in infancy and risk of childhood overweight. Arch Pediatr Adolesc Med (2008) 2.61
Decreasing prevalence of obesity among young children in Massachusetts from 2004 to 2008. Pediatrics (2012) 2.58
Displaying the relatedness among isolates of bacterial species -- the eBURST approach. FEMS Microbiol Lett (2004) 2.56
Racial/ethnic variation in asthma status and management practices among children in managed medicaid. Pediatrics (2002) 2.54
Intrauterine exposure to gestational diabetes, child adiposity, and blood pressure. Am J Hypertens (2008) 2.50
Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis (2010) 2.50
Assigning strains to bacterial species via the internet. BMC Biol (2009) 2.49
Neutral microepidemic evolution of bacterial pathogens. Proc Natl Acad Sci U S A (2005) 2.42
Detection of recombination events in bacterial genomes from large population samples. Nucleic Acids Res (2011) 2.41
Increase in the prevalence of the newly discovered pneumococcal serotype 6C in the nasopharynx after introduction of pneumococcal conjugate vaccine. J Infect Dis (2009) 2.36
Assessing the reliability of eBURST using simulated populations with known ancestry. BMC Microbiol (2007) 2.36
Trends in overweight from 1980 through 2001 among preschool-aged children enrolled in a health maintenance organization. Obesity (Silver Spring) (2006) 2.31
Weight status in the first 6 months of life and obesity at 3 years of age. Pediatrics (2009) 2.30
T(H)17-based vaccine design for prevention of Streptococcus pneumoniae colonization. Cell Host Microbe (2011) 2.30
Real-time influenza forecasts during the 2012-2013 season. Nat Commun (2013) 2.26
Evolutionary dynamics of Vibrio cholerae O1 following a single-source introduction to Haiti. MBio (2013) 2.24
HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response. J Immunol (2005) 2.24
The potential regional impact of contact precaution use in nursing homes to control methicillin-resistant Staphylococcus aureus. Infect Control Hosp Epidemiol (2012) 2.22
Interference between Streptococcus pneumoniae and Staphylococcus aureus: In vitro hydrogen peroxide-mediated killing by Streptococcus pneumoniae. J Bacteriol (2006) 2.22
Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method. PLoS Med (2011) 2.22
Antibody-independent, interleukin-17A-mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide. Infect Immun (2006) 2.20
Construction of otherwise isogenic serotype 6B, 7F, 14, and 19F capsular variants of Streptococcus pneumoniae strain TIGR4. Appl Environ Microbiol (2003) 2.19
Effect of a pediatric hospitalist system on housestaff education and experience. Arch Pediatr Adolesc Med (2002) 2.15
Nontypeable Haemophilus influenzae as a pathogen in children. Pediatr Infect Dis J (2009) 2.12
Randomized controlled trial to improve primary care to prevent and manage childhood obesity: the High Five for Kids study. Arch Pediatr Adolesc Med (2011) 2.12