Chenguang Wang

Author PubWeight™ 188.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 2004 5.22
3 The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma. Cell Cycle 2009 4.69
4 Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study. J Clin Oncol 2009 4.20
5 Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells. Cell Cycle 2010 3.15
6 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol 2008 3.02
7 Akt1 governs breast cancer progression in vivo. Proc Natl Acad Sci U S A 2007 2.67
8 Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation. Cell Cycle 2010 2.45
9 Dose-intensified compared with standard chemotherapy for nonmetastatic Ewing sarcoma family of tumors: a Children's Oncology Group Study. J Clin Oncol 2009 2.44
10 The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. Cell Cycle 2010 2.26
11 Effectiveness of high-dose methotrexate in T-cell lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma: a randomized study by the Children's Oncology Group (POG 9404). Blood 2011 2.04
12 Towards precise classification of cancers based on robust gene functional expression profiles. BMC Bioinformatics 2005 2.01
13 Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem 2005 2.01
14 Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Mol Cell Biol 2006 1.95
15 Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nat Med 2011 1.93
16 Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol 2006 1.91
17 Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol 2003 1.89
18 HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle 2010 1.89
19 p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo. Proc Natl Acad Sci U S A 2009 1.89
20 Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling". Aging (Albany NY) 2010 1.88
21 Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts. Am J Pathol 2009 1.87
22 Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors. Cell Cycle 2011 1.82
23 DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Mol Cell Biol 2006 1.80
24 Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol 2004 1.80
25 Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy. Cancer Biol Ther 2008 1.79
26 Cyclin D1 determines mitochondrial function in vivo. Mol Cell Biol 2006 1.75
27 Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell 2009 1.68
28 Cyclin D1 induction of cellular migration requires p27(KIP1). Cancer Res 2006 1.64
29 ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. J Clin Invest 2012 1.62
30 Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy. Cell Cycle 2009 1.61
31 Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells. Cancer Res 2010 1.55
32 Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest 2012 1.52
33 Noncontrast three-dimensional magnetic resonance imaging vs lymphoscintigraphy in the evaluation of lymph circulation disorders: A comparative study. J Vasc Surg 2005 1.49
34 Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol Cell Biol 2002 1.48
35 DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J Biol Chem 2003 1.47
36 Alternative cyclin D1 splice forms differentially regulate the DNA damage response. Cancer Res 2010 1.45
37 Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer Biol Ther 2011 1.43
38 p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res 2002 1.36
39 Cyclin D1 functions in cell migration. Cell Cycle 2006 1.36
40 Acetylation of nuclear receptors in cellular growth and apoptosis. Biochem Pharmacol 2004 1.34
41 Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. J Biol Chem 2005 1.33
42 Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells. Cell Cycle 2011 1.32
43 microRNA, cell cycle, and human breast cancer. Am J Pathol 2010 1.32
44 Evaluating reproducibility of differential expression discoveries in microarray studies by considering correlated molecular changes. Bioinformatics 2009 1.29
45 The Dachshund gene in development and hormone-responsive tumorigenesis. Trends Endocrinol Metab 2009 1.28
46 Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration. J Biol Chem 2008 1.25
47 Attenuation of Forkhead signaling by the retinal determination factor DACH1. Proc Natl Acad Sci U S A 2010 1.20
48 Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol 2006 1.20
49 Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer. Cancer Res 2014 1.19
50 Altered expression of DACH1 and cyclin D1 in endometrial cancer. Cancer Biol Ther 2009 1.18
51 Regulation of the androgen receptor by SET9-mediated methylation. Nucleic Acids Res 2010 1.17
52 The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. Cancer Res 2009 1.14
53 PPARgamma activation induces autophagy in breast cancer cells. Int J Biochem Cell Biol 2009 1.14
54 The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. J Biol Chem 2004 1.14
55 ErbB2 induces Notch1 activity and function in breast cancer cells. Clin Transl Sci 2008 1.13
56 BRCA1 inhibition of telomerase activity in cultured cells. Mol Cell Biol 2003 1.12
57 Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation. Trends Endocrinol Metab 2007 1.11
58 Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol 2009 1.11
59 Bayesian model selection for incomplete data using the posterior predictive distribution. Biometrics 2012 1.08
60 Dachshund binds p53 to block the growth of lung adenocarcinoma cells. Cancer Res 2013 1.07
61 Effects of replacing the unreliable cDNA microarray measurements on the disease classification based on gene expression profiles and functional modules. Bioinformatics 2006 1.07
62 Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature. Am J Pathol 2009 1.06
63 Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. Am J Pathol 2009 1.05
64 The functional significance of nuclear receptor acetylation. Steroids 2007 1.04
65 Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways. Mol Cancer Ther 2002 1.04
66 Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget 2013 1.03
67 The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer. Oncotarget 2014 1.01
68 Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res 2010 1.00
69 Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res 2013 1.00
70 PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b. Cell Cycle 2011 0.99
71 Nuclear receptor modifications and endocrine cell proliferation. J Steroid Biochem Mol Biol 2003 0.99
72 Globally predicting protein functions based on co-expressed protein-protein interaction networks and ontology taxonomy similarities. Gene 2006 0.99
73 Repression of endometrial tumor growth by targeting SREBP1 and lipogenesis. Cell Cycle 2012 0.97
74 Body weight-dependent pharmacokinetics of busulfan in paediatric haematopoietic stem cell transplantation patients: towards individualized dosing. Clin Pharmacokinet 2012 0.96
75 Cyclin D1 determines estrogen signaling in the mammary gland in vivo. Mol Endocrinol 2013 0.95
76 3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation. Mol Endocrinol 2005 0.94
77 Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancer. Cancer Res 2013 0.94
78 Activating peroxisome proliferator-activated receptor gamma mutant promotes tumor growth in vivo by enhancing angiogenesis. Cancer Res 2009 0.93
79 Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide. Cell Cycle 2013 0.93
80 ErbB2 activation upregulates glutaminase 1 expression which promotes breast cancer cell proliferation. J Cell Biochem 2014 0.92
81 Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors. Clin Cancer Res 2013 0.92
82 miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget 2014 0.92
83 Phylogenetic considerations in designing a broadly protective multimeric L2 vaccine. J Virol 2013 0.92
84 Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation. Am J Pathol 2009 0.91
85 Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. Nat Commun 2013 0.91
86 Tumor-suppressive effects of CDK8 in endometrial cancer cells. Cell Cycle 2013 0.90
87 A computational approach for functional mapping of quantitative trait loci that regulate thermal performance curves. PLoS One 2007 0.90
88 Identification of a tumor-suppressive human-specific microRNA within the FHIT tumor-suppressor gene. Cancer Res 2014 0.90
89 Bayesian approaches in medical device clinical trials: a discussion with examples in the regulatory setting. J Biopharm Stat 2011 0.88
90 Imaging spontaneous MMTVneu transgenic murine mammary tumors: targeting metabolic activity versus genetic products. J Nucl Med 2009 0.87
91 p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling. Cancer Res 2006 0.87
92 Acetylation in hormone signaling and the cell cycle. Cytokine Growth Factor Rev 2002 0.87
93 Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. J Biol Chem 2010 0.86
94 Comparison of different normalization assumptions for analyses of DNA methylation data from the cancer genome. Gene 2012 0.86
95 Intensified PEG-L-asparaginase and antimetabolite-based therapy for treatment of higher risk precursor-B acute lymphoblastic leukemia: a report from the Children's Oncology Group. J Pediatr Hematol Oncol 2007 0.85
96 Epigenetics and the estrogen receptor. Ann N Y Acad Sci 2006 0.85
97 Complex alternative splicing of the smarca2 gene suggests the importance of smarca2-B variants. J Cancer 2011 0.84
98 A causal model for joint evaluation of placebo and treatment-specific effects in clinical trials. Biometrics 2013 0.84
99 Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation. PLoS One 2013 0.84
100 Extensive increase of microarray signals in cancers calls for novel normalization assumptions. Comput Biol Chem 2011 0.83
101 Network analysis of genomic alteration profiles reveals co-altered functional modules and driver genes for glioblastoma. Mol Biosyst 2013 0.83
102 Inhibition of cyclin D1 gene transcription by Brg-1. Cell Cycle 2007 0.83
103 Glutamine depletion and glucose depletion trigger growth inhibition via distinctive gene expression reprogramming. Cell Cycle 2012 0.83
104 Environment-sensitive fluorescent probe: a benzophosphole oxide with an electron-donating substituent. Angew Chem Int Ed Engl 2015 0.82
105 Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle 2013 0.82
106 An NF-kappa B-dependent survival pathway protects against cell death induced by TVB receptors for avian leukosis viruses. J Virol 2002 0.81
107 Extensive up-regulation of gene expression in cancer: the normalised use of microarray data. Mol Biosyst 2012 0.81
108 Nexrutine inhibits survival and induces G1 cell cycle arrest, which is associated with apoptosis or autophagy depending on the breast cancer cell line. Nutr Cancer 2013 0.81
109 Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Mol Biol Cell 2008 0.81
110 Evaluating the consistency of differential expression of microRNA detected in human cancers. Mol Cancer Ther 2011 0.80
111 Estimating the Causal Effect of Low Tidal Volume Ventilation on Survival in Patients with Acute Lung Injury. J R Stat Soc Ser C Appl Stat 2011 0.80
112 Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate. Int J Biochem Cell Biol 2011 0.80
113 AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol. Cell Cycle 2015 0.80
114 A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults. Clin Pharmacokinet 2013 0.80
115 Angiomyolipoma occurred at the cervical spine. Joint Bone Spine 2008 0.80
116 Analysis of pathway mutation profiles highlights collaboration between cancer-associated superpathways. Hum Mutat 2011 0.80
117 Modeling genetic imprinting effects of DNA sequences with multilocus polymorphism data. Algorithms Mol Biol 2009 0.80
118 Histone deacetylase inhibitor AR-42 enhances E7-specific CD8⁺ T cell-mediated antitumor immunity induced by therapeutic HPV DNA vaccination. J Mol Med (Berl) 2013 0.79
119 [Effects of moxibustion on cell proliferative factors in gastric mucosa in rats with precancerous lesions of chronic atrophic gastritis]. Zhongguo Zhen Jiu 2015 0.78
120 A general quantitative genetic model for haplotyping a complex trait in humans. Curr Genomics 2007 0.78
121 Microwave-assisted pyrolysis of microalgae for biofuel production. Bioresour Technol 2011 0.78
122 Evaluation of cDNA microarray data by multiple clones mapping to the same transcript. OMICS 2009 0.78
123 Risk haplotype analysis for bovine paratuberculosis. Mamm Genome 2009 0.78
124 Computed tomographic and magnetic resonance imaging presentations of pancreatitis maldiagnosed as pancreatic carcinoma. Pancreas 2010 0.77
125 Combination of phosphatidylinositol 3-kinases pathway inhibitor and photodynamic therapy in endothelial and tumor cells. Photochem Photobiol 2012 0.77
126 Targeting epigenetics for the treatment of prostate cancer: recent progress and future directions. Semin Oncol 2013 0.77
127 Effect of Robo4 on retinal endothelial permeability. Curr Eye Res 2012 0.77
128 An electrochemical immunosensor for quantitative detection of ficolin-3. Nanotechnology 2016 0.76
129 Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration. Mol Endocrinol 2014 0.76
130 Functional comparison between genes dysregulated in ulcerative colitis and colorectal carcinoma. PLoS One 2013 0.76
131 A Comparative Treatment Study of Intravitreal Voriconazole and Liposomal Amphotericin B in an Aspergillus fumigatus Endophthalmitis Model. Invest Ophthalmol Vis Sci 2015 0.75
132 An implantable device for neuropsychiatric rehabilitation by chronic deep brain stimulation in freely moving rats. Neuroreport 2017 0.75
133 Pitfalls in experimental designs for characterizing the transcriptional, methylational and copy number changes of oncogenes and tumor suppressor genes. PLoS One 2013 0.75
134 Discussion of "Missing Data Methods in Longitudinal Studies: A Review" by Ibrahim and Molenberghs. Test (Madr) 2009 0.75
135 Prospective EHR-based clinical trials: the challenge of missing data. J Gen Intern Med 2014 0.75
136 Systems mapping of metabolic genes through control theory. Adv Drug Deliv Rev 2013 0.75
137 High-resolution triple-color patterns based on the liquid behavior of organic molecules. Small 2011 0.75
138 Novel robust skylight compass method based on full-sky polarization imaging under harsh conditions. Opt Express 2016 0.75
139 Retrievals of all-weather daytime land surface temperature from FengYun-2D data. Opt Express 2017 0.75
140 Kinetic modeling of ethane pyrolysis at high conversion. J Phys Chem A 2011 0.75
141 A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Invest New Drugs 2005 0.75
142 Synthesis and photophysical properties of phosphorus(V) porphyrins functionalized with axial carbazolylvinylnaphthalimides. Org Biomol Chem 2012 0.75
143 Optimizing the order of hypotheses in serial testing of multiple endpoints in clinical trials. Stat Med 2015 0.75
144 Addressable organic structure by anisotropic wetting. Adv Mater 2013 0.75
145 Three-dimensional attitude determination strategy for fused polarized light and geomagnetism. Appl Opt 2022 0.75
146 Real-time quantitative nicking endonuclease-mediated isothermal amplification with small molecular beacons. Analyst 2016 0.75
147 Gray consistency optical flow algorithm based on mask-R-CNN and a spatial filter for velocity calculation. Appl Opt 2021 0.75
148 Diagnosis of inguinal lymph node metastases using contrast enhanced high resolution MR lymphangiography. Acad Radiol 2012 0.75
149 Novel urea-functionalized quinacridone derivatives: ultrasound and thermo effects on supramolecular organogels. Chemistry 2010 0.75
150 Signal transduction inhibitors in cellular function. Methods Mol Biol 2004 0.75