1
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Multivalency as a chemical organization and action principle.
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Angew Chem Int Ed Engl
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2012
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1.97
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2
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Akt1 controls insulin-driven VEGF biosynthesis from keratinocytes: implications for normal and diabetes-impaired skin repair in mice.
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J Invest Dermatol
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2008
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1.62
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3
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Positive sentinel lymph nodes are a negative prognostic factor for survival in T1-2 oral/oropharyngeal cancer-a long-term study on 103 patients.
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Ann Surg Oncol
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2008
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1.60
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4
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Native chemical ligation at valine.
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Angew Chem Int Ed Engl
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2008
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1.48
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5
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Adult palatum as a novel source of neural crest-related stem cells.
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Stem Cells
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2009
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1.45
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6
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New cyanine dyes as base surrogates in PNA: forced intercalation probes (FIT-probes) for homogeneous SNP detection.
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Bioorg Med Chem
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2007
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1.07
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7
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Forced intercalation probes (FIT Probes): thiazole orange as a fluorescent base in peptide nucleic acids for homogeneous single-nucleotide-polymorphism detection.
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Chembiochem
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2005
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1.01
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8
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Triplex molecular beacons as modular probes for DNA detection.
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Angew Chem Int Ed Engl
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2007
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1.00
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9
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DNA-catalyzed transfer of a reporter group.
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J Am Chem Soc
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2006
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1.00
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10
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Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs.
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Nucleic Acids Res
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2011
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1.00
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11
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9-Fluorenylmethoxycarbonyl-based solid-phase synthesis of peptide α-thioesters.
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Angew Chem Int Ed Engl
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2010
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0.97
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12
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Solid-phase synthesis of peptide thioesters with self-purification.
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Angew Chem Int Ed Engl
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2007
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0.97
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13
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Brief S2k guidelines--Merkel cell carcinoma.
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J Dtsch Dermatol Ges
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2013
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0.96
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14
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Infrared characterization of interfacial Si-O bond formation on silanized flat SiO2/Si surfaces.
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Langmuir
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2010
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0.96
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15
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Brightness enhanced DNA FIT-probes for wash-free RNA imaging in tissue.
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J Am Chem Soc
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2013
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0.93
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16
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Single-nucleotide-specific PNA-peptide ligation on synthetic and PCR DNA templates.
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J Am Chem Soc
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2004
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0.92
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17
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Polycyclic aromatic DNA-base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase.
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Angew Chem Int Ed Engl
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2003
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0.92
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18
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Combined cetuximab and reirradiation for locoregional recurrent and inoperable squamous cell carcinoma of the head and neck.
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Strahlenther Onkol
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2009
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0.91
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19
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Achieving turnover in DNA-templated reactions.
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Chembiochem
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2008
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0.91
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20
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An exploratory pilot study into the association between microcirculatory parameters derived by MRI-based pharmacokinetic analysis and glucose utilization estimated by PET-CT imaging in head and neck cancer.
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Eur Radiol
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2010
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0.91
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21
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Low-noise stemless PNA beacons for sensitive DNA and RNA detection.
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Angew Chem Int Ed Engl
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2008
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0.90
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22
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Fluorescence imaging of influenza H1N1 mRNA in living infected cells using single-chromophore FIT-PNA.
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Angew Chem Int Ed Engl
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2011
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0.89
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23
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Target-catalyzed transfer reactions for the amplified detection of RNA.
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Angew Chem Int Ed Engl
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2008
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0.88
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24
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Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21.
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Angew Chem Int Ed Engl
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2008
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0.88
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25
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Lipid domain specific recruitment of lipophilic nucleic acids: a key for switchable functionalization of membranes.
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J Am Chem Soc
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2010
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0.88
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26
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As fast and selective as enzymatic ligations: unpaired nucleobases increase the selectivity of DNA-controlled native chemical PNA ligation.
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Chembiochem
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2005
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0.87
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27
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Ligation-desulfurization: a powerful combination in the synthesis of peptides and glycopeptides.
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Biopolymers
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2010
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0.87
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28
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Induction and detection of human mesenchymal stem cell migration in the 48-well reusable transwell assay.
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Stem Cells Dev
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2005
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0.87
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29
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A preliminary report about treatment of bisphosphonate related osteonecrosis of the jaw with Er:YAG laser ablation.
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Lasers Surg Med
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2009
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0.87
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30
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DNA-guided display of proteins and protein ligands for the interrogation of biology.
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Chem Soc Rev
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2011
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0.86
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31
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Brightness through local constraint--LNA-enhanced FIT hybridization probes for in vivo ribonucleotide particle tracking.
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Angew Chem Int Ed Engl
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2014
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0.86
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32
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Convergent synthesis of peptide nucleic acids by native chemical ligation.
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Org Lett
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2005
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0.86
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33
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DNA as a molecular ruler: interrogation of a tandem SH2 domain with self-assembled, bivalent DNA-peptide complexes.
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Angew Chem Int Ed Engl
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2011
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0.86
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34
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Nucleic acid templated reactions: consequences of probe reactivity and readout strategy for amplified signaling and sequence selectivity.
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Chemistry
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2009
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0.86
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35
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Reducing product inhibition in DNA-template-controlled ligation reactions.
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Angew Chem Int Ed Engl
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2006
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0.86
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36
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Large dynamic Stokes shift of DNA intercalation dye Thiazole Orange has contribution from a high-frequency mode.
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J Am Chem Soc
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2006
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0.86
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37
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Single nucleotide specific detection of DNA by native chemical ligation of fluorescence labeled PNA-probes.
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Bioorg Med Chem
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2007
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0.85
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38
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Automated Fmoc-based solid-phase synthesis of peptide thioesters with self-purification effect and application in the construction of immobilized SH3 domains.
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J Am Chem Soc
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2010
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0.85
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39
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Diastereoselective synthesis of beta-Aryl-C-nucleosides from 1,2-anhydrosugars.
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Org Lett
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2006
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0.85
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40
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Palatal versus vestibular piezoelectric window osteotomy for maxillary sinus elevation: a comparative clinical study of two surgical techniques.
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Oral Surg Oral Med Oral Pathol Oral Radiol Endod
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2009
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0.85
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41
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Hairpin peptide beacon: dual-labeled PNA-peptide-hybrids for protein detection.
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J Am Chem Soc
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2007
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42
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Diels-Alder ligation of peptides and proteins.
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Chemistry
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2006
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0.84
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43
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FIT probes: peptide nucleic acid probes with a fluorescent base surrogate enable real-time DNA quantification and single nucleotide polymorphism discovery.
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Anal Biochem
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2008
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0.84
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44
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Extending the scope of native chemical peptide coupling.
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Angew Chem Int Ed Engl
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2008
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45
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Synthesis of protein-nucleic acid conjugates by expressed protein ligation.
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Chem Commun (Camb)
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2003
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46
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O-Allyl protection in the Fmoc-based synthesis of difficult PNA.
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Org Biomol Chem
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2008
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0.84
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47
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Ascorbate as an alternative to thiol additives in native chemical ligation.
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Chembiochem
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2011
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0.83
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48
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Thiazole orange as fluorescent universal base in peptide nucleic acids.
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Chem Commun (Camb)
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2003
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0.83
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49
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Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding.
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Chembiochem
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2011
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0.83
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50
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Nuclear NF-κB expression correlates with outcome among patients with head and neck squamous cell carcinoma treated with primary chemoradiation therapy.
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Int J Radiat Oncol Biol Phys
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2013
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0.83
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51
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Reirradiation with cetuximab in locoregional recurrent and inoperable squamous cell carcinoma of the head and neck: feasibility and first efficacy results.
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Int J Radiat Oncol Biol Phys
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2012
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0.82
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52
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DNA-controlled bivalent presentation of ligands for the estrogen receptor.
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Angew Chem Int Ed Engl
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2011
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0.82
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53
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Consecutive signal amplification for DNA detection based on de novo fluorophore synthesis and host-guest chemistry.
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Angew Chem Int Ed Engl
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2012
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0.82
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54
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Esthetic outcome of implant-based reconstructions in augmented bone: comparison of autologous and allogeneic bone block grafting with the pink esthetic score (PES).
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Head Face Med
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2014
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0.82
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55
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PNA FIT-probes for the dual color imaging of two viral mRNA targets in influenza H1N1 infected live cells.
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Bioconjug Chem
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2012
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0.82
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56
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Single labeled DNA FIT probes for avoiding false-positive signaling in the detection of DNA/RNA in qPCR or cell media.
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Chembiochem
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2012
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0.82
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57
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DNA-triggered synthesis and bioactivity of proapoptotic peptides.
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Angew Chem Int Ed Engl
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2011
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0.81
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58
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Dual fluorophore PNA FIT-probes--extremely responsive and bright hybridization probes for the sensitive detection of DNA and RNA.
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Org Biomol Chem
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2012
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0.81
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59
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Native chemical ligation in the synthesis of internally modified oligonucleotide-peptide conjugates.
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Biopolymers
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2010
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0.81
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60
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Amplification by nucleic acid-templated reactions.
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Org Biomol Chem
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2014
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61
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The role of reactivity in DNA templated native chemical PNA ligation during PCR.
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Bioorg Med Chem
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2013
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0.80
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62
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Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.
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Chembiochem
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2013
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0.80
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63
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Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization.
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Org Biomol Chem
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2010
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64
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Peptide-templated acyl transfer: a chemical method for the labeling of membrane proteins on live cells.
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Angew Chem Int Ed Engl
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2014
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0.79
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65
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Synthetic bone substitute material comparable with xenogeneic material for bone tissue regeneration in oral cancer patients: First and preliminary histological, histomorphometrical and clinical results.
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Ann Maxillofac Surg
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2013
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66
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Molecular beacons: signalling nucleic acid probes, methods, and protocols. Preface.
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Methods Mol Biol
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2008
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67
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Local disruption of DNA-base stacking by bulky base surrogates.
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Chem Commun (Camb)
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2002
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68
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Chemical properties of oxidized silicon carbide surfaces upon etching in hydrofluoric acid.
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J Am Chem Soc
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2009
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0.78
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69
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New isocysteine building blocks and chemoselective peptide ligation.
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Org Biomol Chem
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2003
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0.77
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70
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Efficient radiative and nonradiative energy transfer from proximal CdSe/ZnS nanocrystals into silicon nanomembranes.
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ACS Nano
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2012
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0.77
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71
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Double-clicking peptides onto phosphorothioate oligonucleotides: combining two proapoptotic agents in one molecule.
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Angew Chem Int Ed Engl
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2014
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0.77
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72
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Promoting strand exchange in a DNA-templated transfer reaction.
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Chem Commun (Camb)
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2012
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73
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DNA-triggered dye transfer on a quantum dot.
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Bioconjug Chem
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2013
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0.77
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74
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Exploring base-pair-specific optical properties of the DNA stain thiazole orange.
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Chemistry
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2007
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0.77
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75
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Total synthesis of proximicin A-C and synthesis of new furan-based DNA binding agents.
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Org Lett
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2009
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0.77
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76
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Radiation damage to alkyl chain monolayers on semiconductor substrates investigated by electron spectroscopy.
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J Phys Chem B
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2006
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0.77
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77
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Er:YAG laser osteotomy for intraoral bone grafting procedures: a case series with a fiber-optic delivery system.
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J Periodontol
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2007
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0.77
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78
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Reducing product inhibition in nucleic acid-templated ligation reactions: DNA-templated cycligation.
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Chembiochem
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2013
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79
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Tight spatial and temporal control in dynamic basal to distal migration of epithelial inflammatory responses and infiltration of cytoprotective macrophages determine healing skin flap transplants in mice.
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Ann Surg
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2009
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0.77
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80
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Six years clinical experience with the dorsally pedicled buccal musculomucosal flap.
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Ann Plast Surg
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2009
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0.77
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81
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DNA and RNA-controlled switching of protein kinase activity.
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Chembiochem
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2009
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0.76
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82
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FIT-probes in real-time PCR.
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Methods Mol Biol
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2008
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83
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Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair.
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Mol Pharmacol
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2008
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0.76
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84
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Remote control of lipophilic nucleic acids domain partitioning by DNA hybridization and enzymatic cleavage.
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J Am Chem Soc
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2012
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85
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DNA-controlled reversible switching of peptide conformation and bioactivity.
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Angew Chem Int Ed Engl
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2007
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86
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Protease probes that enable excimer signaling upon scission.
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Angew Chem Int Ed Engl
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2014
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87
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Controlling the activity of peptides and proteins with smart nucleic acid-protein hybrids.
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Org Biomol Chem
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2008
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[The Er:YAG laser in dentoalveolar surgery].
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Schweiz Monatsschr Zahnmed
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2007
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89
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Concise synthesis of aryl-C-nucleosides by Friedel-Crafts alkylation.
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Org Biomol Chem
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2005
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0.75
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90
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Synthesis of C-aryl-nucleosides and O-aryl-glycosides via cuprate glycosylation.
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J Org Chem
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2007
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0.75
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91
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Direct coupling of annexin A5 to VSOP yields small, protein-covered nanoprobes for MR imaging of apoptosis.
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Contrast Media Mol Imaging
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2014
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92
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DNA made of purines only.
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Chem Biol
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2007
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93
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Binaphthyl-DNA: stacking and fluorescence of a nonplanar aromatic base surrogate in DNA.
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Angew Chem Int Ed Engl
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2009
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0.75
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94
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Sequence-specific imaging of influenza A mRNA in living infected cells using fluorescent FIT-PNA.
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Methods Mol Biol
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2013
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0.75
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95
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Spatial screening of hemagglutinin on Influenza A virus particles: Sialyl-LacNAc displays on DNA and PEG scaffolds reveal the requirements for bivalency enhanced interactions with weak monovalent binders.
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J Am Chem Soc
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2017
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96
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Histologic characterization of human extraction sockets 3 years after grafting: a case report.
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Int J Periodontics Restorative Dent
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2015
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97
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Inducing the replacement of PNA in DNA.PNA duplexes by DNA.
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Bioorg Med Chem
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2007
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98
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Advantages and limits of 3-segment (paramedian) versus 2-segment (median) surgically assisted rapid maxillary expansion (SARME).
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Oral Surg Oral Med Oral Pathol Oral Radiol
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2011
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0.75
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99
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Bioorganic chemistry meeting in Wales.
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Chembiochem
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2002
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100
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DNA-templated native chemical ligation of functionalized peptide nucleic acids: a versatile tool for single base-specific detection of nucleic acids.
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Methods Mol Biol
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2014
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101
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Visible to near-infrared sensitization of silicon substrates via energy transfer from proximal nanocrystals: further insights for hybrid photovoltaics.
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ACS Nano
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2013
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102
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Comparison of bipartite versus tripartite osteotomy for maxillary transversal expansion using 3-dimensional preoperative and postexpansion computed tomography data.
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J Oral Maxillofac Surg
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2009
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103
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DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides.
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Bioorg Med Chem Lett
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2011
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104
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Synthesis and evaluation of a netropsin-proximicin-hybrid library for DNA binding and cytotoxicity.
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Bioorg Med Chem Lett
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2009
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105
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Ensemble hybridisation--a new method for exploring sequence dependent fluorescence of dye-nucleic acid conjugates.
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Chem Commun (Camb)
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2004
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106
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Nucleic acids: new life, new materials.
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Org Biomol Chem
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2013
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107
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Solid phase synthesis of short peptide-based multimetal tags for biomolecule labeling.
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Bioconjug Chem
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2014
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New aspects in fragmentation of peptide nucleic acids: comparison of positive and negative ions by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
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Rapid Commun Mass Spectrom
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2009
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Gold nanoparticles on oxide-free silicon-molecule interface for single electron transport.
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Langmuir
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2013
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N-->O-Acyl shift in Fmoc-based synthesis of phosphopeptides.
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Org Biomol Chem
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2008
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