| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
|
Nat Genet
|
2007
|
12.62
|
|
2
|
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.
|
Nature
|
2010
|
12.27
|
|
3
|
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
Nat Genet
|
2010
|
9.90
|
|
4
|
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
|
Nat Genet
|
2010
|
8.55
|
|
5
|
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
Nat Genet
|
2010
|
8.48
|
|
6
|
Rheumatoid arthritis association at 6q23.
|
Nat Genet
|
2007
|
6.71
|
|
7
|
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
|
PLoS Genet
|
2008
|
5.85
|
|
8
|
Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites.
|
Am J Hum Genet
|
2004
|
4.76
|
|
9
|
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
Nat Genet
|
2012
|
4.46
|
|
10
|
Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom.
|
Arthritis Rheum
|
2002
|
3.78
|
|
11
|
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.
|
Nat Genet
|
2009
|
3.52
|
|
12
|
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.
|
Cell
|
2013
|
3.49
|
|
13
|
Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.
|
Arthritis Rheum
|
2008
|
2.93
|
|
14
|
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.
|
Arthritis Rheum
|
2005
|
2.93
|
|
15
|
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
Nat Genet
|
2010
|
2.56
|
|
16
|
Impact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis.
|
Arthritis Care Res (Hoboken)
|
2014
|
2.11
|
|
17
|
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
|
Arthritis Rheum
|
2010
|
2.08
|
|
18
|
Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.
|
Ann Rheum Dis
|
2006
|
1.99
|
|
19
|
Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.
|
Arthritis Rheum
|
2009
|
1.95
|
|
20
|
Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.
|
Arthritis Res Ther
|
2010
|
1.85
|
|
21
|
Informed conditioning on clinical covariates increases power in case-control association studies.
|
PLoS Genet
|
2012
|
1.57
|
|
22
|
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.
|
PLoS Genet
|
2013
|
1.54
|
|
23
|
Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci.
|
Arthritis Rheum
|
2011
|
1.44
|
|
24
|
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
|
Hum Mol Genet
|
2009
|
1.37
|
|
25
|
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.
|
Ann Rheum Dis
|
2013
|
1.37
|
|
26
|
Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.
|
Ann Rheum Dis
|
2010
|
1.36
|
|
27
|
Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.
|
Am J Hum Genet
|
2012
|
1.35
|
|
28
|
Investigation of association of the IL12B and IL23R genes with psoriatic arthritis.
|
Arthritis Rheum
|
2008
|
1.28
|
|
29
|
Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
|
Arthritis Rheum
|
2009
|
1.23
|
|
30
|
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
|
Nat Genet
|
2013
|
1.21
|
|
31
|
Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis.
|
Ann Rheum Dis
|
2011
|
1.17
|
|
32
|
Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort.
|
Arthritis Rheum
|
2012
|
1.17
|
|
33
|
Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis.
|
Arthritis Rheum
|
2005
|
1.16
|
|
34
|
Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis.
|
Hum Mol Genet
|
2008
|
1.16
|
|
35
|
Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.
|
Ann Rheum Dis
|
2012
|
1.14
|
|
36
|
Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.
|
Ann Rheum Dis
|
2009
|
1.10
|
|
37
|
Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis.
|
Ann Rheum Dis
|
2012
|
1.10
|
|
38
|
Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.
|
Arthritis Rheum
|
2009
|
1.09
|
|
39
|
HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis.
|
Ann Rheum Dis
|
2007
|
1.08
|
|
40
|
Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
|
Ann Rheum Dis
|
2009
|
1.07
|
|
41
|
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
|
Ann Rheum Dis
|
2009
|
1.06
|
|
42
|
Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.
|
Ann Rheum Dis
|
2010
|
1.06
|
|
43
|
Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis.
|
Ann Rheum Dis
|
2010
|
1.03
|
|
44
|
Genetic and genomic predictors of anti-TNF response.
|
Pharmacogenomics
|
2011
|
1.02
|
|
45
|
Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
|
Ann Rheum Dis
|
2012
|
1.01
|
|
46
|
Investigation of rheumatoid arthritis genetic susceptibility markers in the early rheumatoid arthritis study further replicates the TRAF1 association with radiological damage.
|
J Rheumatol
|
2012
|
0.98
|
|
47
|
The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.
|
Rheumatology (Oxford)
|
2010
|
0.98
|
|
48
|
Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.
|
Arthritis Res Ther
|
2010
|
0.98
|
|
49
|
Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.
|
Arthritis Rheum
|
2004
|
0.97
|
|
50
|
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
|
PLoS Genet
|
2013
|
0.96
|
|
51
|
Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris.
|
Ann Rheum Dis
|
2011
|
0.96
|
|
52
|
Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.
|
Ann Rheum Dis
|
2010
|
0.96
|
|
53
|
Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.
|
Hum Mutat
|
2012
|
0.94
|
|
54
|
Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.
|
Ann Rheum Dis
|
2010
|
0.93
|
|
55
|
Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.
|
PLoS One
|
2010
|
0.93
|
|
56
|
Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis.
|
Arthritis Res Ther
|
2011
|
0.93
|
|
57
|
Update on the genetic risk factors for rheumatoid arthritis.
|
Expert Rev Clin Immunol
|
2010
|
0.92
|
|
58
|
Investigation of association between the TRAF family genes and RA susceptibility.
|
Ann Rheum Dis
|
2007
|
0.92
|
|
59
|
Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
|
Ann Rheum Dis
|
2012
|
0.91
|
|
60
|
Variants in RUNX3 contribute to susceptibility to psoriatic arthritis, exhibiting further common ground with ankylosing spondylitis.
|
Arthritis Rheum
|
2013
|
0.91
|
|
61
|
Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.
|
Pharmacogenet Genomics
|
2009
|
0.91
|
|
62
|
The potential use of expression profiling: implications for predicting treatment response in rheumatoid arthritis.
|
Ann Rheum Dis
|
2013
|
0.91
|
|
63
|
The role of DMARDs in reducing the immunogenicity of TNF inhibitors in chronic inflammatory diseases.
|
Rheumatology (Oxford)
|
2013
|
0.90
|
|
64
|
Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.
|
Ann Rheum Dis
|
2010
|
0.90
|
|
65
|
Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort.
|
Arthritis Rheum
|
2006
|
0.89
|
|
66
|
The genetics of psoriatic arthritis: lessons from genome-wide association studies.
|
Discov Med
|
2010
|
0.88
|
|
67
|
Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.
|
Arthritis Rheum
|
2013
|
0.88
|
|
68
|
Expression of the autoimmunity associated TNFAIP3 is increased in rheumatoid arthritis but does not differ according to genotype at 6q23.
|
Rheumatology (Oxford)
|
2012
|
0.87
|
|
69
|
Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease.
|
Ann Rheum Dis
|
2009
|
0.87
|
|
70
|
Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis.
|
Arthritis Res Ther
|
2012
|
0.87
|
|
71
|
Benefit of early treatment in inflammatory polyarthritis patients with anti-cyclic citrullinated peptide antibodies versus those without antibodies.
|
Arthritis Care Res (Hoboken)
|
2010
|
0.86
|
|
72
|
Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.
|
Arthritis Res Ther
|
2012
|
0.86
|
|
73
|
ASSIMILATOR: a new tool to inform selection of associated genetic variants for functional studies.
|
Bioinformatics
|
2011
|
0.86
|
|
74
|
Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p.
|
Arthritis Rheum
|
2004
|
0.86
|
|
75
|
Increasing age at symptom onset is associated with worse radiological damage at presentation in patients with early inflammatory polyarthritis.
|
Ann Rheum Dis
|
2006
|
0.85
|
|
76
|
Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
|
Arthritis Rheumatol
|
2014
|
0.85
|
|
77
|
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.
|
Hum Genet
|
2010
|
0.85
|
|
78
|
Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.
|
Arthritis Res Ther
|
2012
|
0.85
|
|
79
|
Genetic susceptibility factors for psoriatic arthritis.
|
Curr Opin Rheumatol
|
2010
|
0.84
|
|
80
|
Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition.
|
BMC Genet
|
2005
|
0.84
|
|
81
|
Genetic variation in CCR5 does not predict clinical outcome in inflammatory arthritis.
|
Arthritis Rheum
|
2003
|
0.84
|
|
82
|
Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population.
|
Ann Rheum Dis
|
2009
|
0.84
|
|
83
|
Heterogeneity of anticitrullinated peptide antibodies and response to anti-tumor necrosis factor agents in rheumatoid arthritis.
|
J Rheumatol
|
2012
|
0.84
|
|
84
|
Investigation of an interleukin-6 receptor gene polymorphism (rs2228145) as a predictor of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.
|
Ann Rheum Dis
|
2013
|
0.84
|
|
85
|
Relationship between area-level socio-economic deprivation and autoantibody status in patients with rheumatoid arthritis: multicentre cross-sectional study.
|
Ann Rheum Dis
|
2012
|
0.84
|
|
86
|
Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis.
|
Rheumatology (Oxford)
|
2012
|
0.84
|
|
87
|
Lack of association of variants previously associated with anti-TNF medication response in rheumatoid arthritis patients: results from a homogeneous Greek population.
|
PLoS One
|
2013
|
0.83
|
|
88
|
Investigation of IL1, VEGF, PPARG and MEFV genes in psoriatic arthritis susceptibility.
|
Ann Rheum Dis
|
2011
|
0.82
|
|
89
|
Economics of stratified medicine in rheumatoid arthritis.
|
Curr Rheumatol Rep
|
2014
|
0.82
|
|
90
|
Genetic epidemiology of psoriatic arthritis.
|
Mod Rheumatol
|
2004
|
0.81
|
|
91
|
Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response.
|
Pharmacogenet Genomics
|
2010
|
0.81
|
|
92
|
Fine mapping of genes within the IDDM8 region in rheumatoid arthritis.
|
Arthritis Res Ther
|
2006
|
0.81
|
|
93
|
Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.
|
Rheumatology (Oxford)
|
2009
|
0.81
|
|
94
|
Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.
|
Arthritis Care Res (Hoboken)
|
2010
|
0.81
|
|
95
|
Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
|
Arthritis Res Ther
|
2006
|
0.80
|
|
96
|
TNFR2 is not associated with rheumatoid arthritis susceptibility in a Caucasian population.
|
Arthritis Rheum
|
2005
|
0.78
|
|
97
|
What have genome-wide studies told us about psoriatic arthritis?
|
Curr Rheumatol Rep
|
2012
|
0.78
|
|
98
|
The bacterial skin microbiome in psoriatic arthritis, an unexplored link in pathogenesis: challenges and opportunities offered by recent technological advances.
|
Rheumatology (Oxford)
|
2013
|
0.77
|
|
99
|
No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort.
|
Ann Rheum Dis
|
2009
|
0.76
|
|
100
|
Genetics and the impact on treatment protocols in patients with rheumatoid arthritis.
|
Expert Rev Clin Immunol
|
2012
|
0.76
|
|
101
|
Pharmacogenetics of treatment response in psoriatic arthritis.
|
Curr Rheumatol Rep
|
2015
|
0.76
|
|
102
|
Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis.
|
Rheumatology (Oxford)
|
2009
|
0.76
|
|
103
|
Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.
|
Nat Genet
|
2015
|
0.75
|
|
104
|
Reply: To PMID 24339425.
|
Arthritis Care Res (Hoboken)
|
2015
|
0.75
|
|
105
|
Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure.
|
BMC Genet
|
2003
|
0.75
|
|
106
|
Investigation of association of the DLG5 gene with psoriatic arthritis.
|
Ann Rheum Dis
|
2007
|
0.75
|
|
107
|
Investigation of C reactive protein gene polymorphisms as predictors of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.
|
Ann Rheum Dis
|
2013
|
0.75
|
|
108
|
Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA.
|
J Rheumatol
|
2012
|
0.75
|
|
109
|
Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.
|
Nat Commun
|
2015
|
0.75
|
|
110
|
Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach.
|
Ann Rheum Dis
|
2013
|
0.75
|
|
111
|
Idiopathic orbital inflammation successfully treated using rituximab in a patient with rheumatoid arthritis.
|
J Rheumatol
|
2012
|
0.75
|
|
112
|
Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
|
Nat Commun
|
2016
|
0.75
|