Published in Drug Metab Lett on April 01, 2010
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Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. Crit Care Med (2013) 2.31
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The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition. Pharmacol Rev (2012) 1.10
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Risperidone prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. J Cardiovasc Pharmacol (2003) 0.90
Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure. Br J Clin Pharmacol (2008) 0.89
Validation of warfarin pharmacogenetic algorithms in clinical practice. Pharmacogenomics (2012) 0.88
Drug-induced long QT syndrome in women: review of current evidence and remaining gaps. Gend Med (2008) 0.86
Genetic determinants of response to aspirin: appraisal of 4 candidate genes. Thromb Res (2011) 0.84
The influence of CYP2D6 phenotype on the clinical response of nebivolol in patients with essential hypertension. Br J Clin Pharmacol (2006) 0.84
Lengthening of cardiac repolarization in isolated guinea pigs hearts by sequential or concomitant administration of two IKr blockers. J Pharm Sci (2010) 0.84
Association between renal function and CYP3A5 genotype in heart transplant recipients treated with calcineurin inhibitors. J Heart Lung Transplant (2010) 0.83
Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy. J Popul Ther Clin Pharmacol (2013) 0.82
Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination. Theor Biol Med Model (2009) 0.81
QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. Fundam Clin Pharmacol (2011) 0.81
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Detection and prevention of drug-drug interactions in the hospitalized elderly: utility of new cytochrome p450-based software. Am J Geriatr Pharmacother (2011) 0.81
Multiple-dose pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered over 21 days with lopinavir-ritonavir in human immunodeficiency virus type 1-infected subjects. Antimicrob Agents Chemother (2008) 0.81
Olanzapine prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. J Psychopharmacol (2006) 0.80
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Effect of a single dose of ritonavir on the pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered in healthy volunteers. Antimicrob Agents Chemother (2008) 0.80
Gender-related differences in drug-induced prolongation of cardiac repolarization in prepubertal guinea pigs. J Cardiovasc Pharmacol Ther (2009) 0.80
Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism. PLoS One (2010) 0.80
Platelet count, not oxidative stress, may contribute to inadequate platelet inhibition by aspirin. Int J Cardiol (2009) 0.79
Effects of AGTR1 A1166C gene polymorphism in patients with heart failure treated with candesartan. Ann Pharmacother (2008) 0.79
Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents. J Mol Cell Cardiol (2009) 0.79
Week-long high-maintenance dose clopidogrel regimen achieves better platelet aggregation inhibition than a standard loading dose before percutaneous coronary intervention: results of a double-blind, randomized clinical trial. J Interv Cardiol (2009) 0.79
Role of CYP2D6 in the stereoselective disposition of venlafaxine in humans. Pharmacogenetics (2003) 0.78
Characterization of CYP3A isozymes involved in the metabolism of domperidone: role of cytochrome b5 and inhibition by ketoconazole. Drug Metab Lett (2010) 0.78
Increased risk of myocardial infarction associated with angiotensin-converting enzyme gene polymorphism is age dependent. J Clin Pharmacol (2010) 0.78
Rosuvastatin blocks hERG current and prolongs cardiac repolarization. J Pharm Sci (2011) 0.77
Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy. Ther Drug Monit (2015) 0.77
PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients. Pharmacogenet Genomics (2012) 0.75
Performance of different population pharmacokinetic algorithms. Ther Drug Monit (2011) 0.75
Inhibitory effects of propafenone on the pharmacokinetics of caffeine in humans. Ther Drug Monit (2006) 0.75
Effects of ciprofloxacin on the stereoselective disposition of mexiletine in man. Ther Drug Monit (2004) 0.75
Enantioselective quantification of carvedilol in human plasma by HPLC in heavily medicated heart failure patients. J Pharm Biomed Anal (2010) 0.75
High-dose venlafaxine treatment in a depressed patient with a genetic CYP2D6 deficiency. Int J Psychiatry Clin Pract (2004) 0.75
Modulatory role of verapamil treatment on the cardiac electrophysiological effects of cisapride. Can J Physiol Pharmacol (2006) 0.75
Combined administration of quinidine and propafenone for atrial fibrillation: the CAQ-PAF study. J Clin Pharmacol (2012) 0.75
An improved HPLC assay with fluorescence detection for the determination of domperidone and three major metabolites for application to in vitro drug metabolism studies. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.75
Evaluation of Limited Sampling Methods for Oral Busulfan Pharmacokinetic Monitoring in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation. Ther Drug Monit (2016) 0.75