R P Schleimer

Author PubWeight™ 135.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters. J Immunol 1986 3.41
2 Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. J Exp Med 1991 2.76
3 Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor. Infect Immun 1998 1.87
4 Activation of eotaxin gene transcription by NF-kappa B and STAT6 in human airway epithelial cells. J Immunol 1999 1.83
5 Human lung mast cells: purification and characterization. J Immunol 1982 1.78
6 Generation of leukotrienes by purified human lung mast cells. J Clin Invest 1982 1.77
7 Studies on the adhesive interaction between purified human eosinophils and cultured vascular endothelial cells. J Immunol 1988 1.68
8 IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J Immunol 1995 1.68
9 Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy 2001 1.63
10 Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES. J Immunol 2000 1.52
11 Arachidonic acid metabolism in purified human lung mast cells. J Immunol 1984 1.47
12 Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils. J Allergy Clin Immunol 2000 1.46
13 Episodic eosinophilia-myalgia-like syndrome in a patient without L-tryptophan use: association with eosinophil activation and increased serum levels of granulocyte-macrophage colony-stimulating factor. J Allergy Clin Immunol 1991 1.45
14 Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. Am J Respir Cell Mol Biol 2001 1.42
15 Eosinophils in health and disease: the LIAR hypothesis. Clin Exp Allergy 2010 1.41
16 Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. J Clin Invest 1983 1.41
17 Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES. J Immunol 1994 1.38
18 Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and eosinophil adhesion molecules in IL-1 beta-induced transendothelial migration. J Immunol 1992 1.38
19 Heterogeneity of human mast cells. J Immunol 1983 1.37
20 Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and glucocorticoids. J Immunol 1995 1.33
21 Recombinant IL-3 induces histamine release from human basophils. J Immunol 1989 1.31
22 Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood 1995 1.30
23 Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J Clin Invest 1997 1.22
24 Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor. J Immunol 1991 1.21
25 Chemokines and allergic disease. J Allergy Clin Immunol 1999 1.20
26 Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy 2012 1.18
27 Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes. J Immunol 2000 1.16
28 Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds. J Infect Dis 1994 1.15
29 Dispersed human lung mast cells. Pharmacologic aspects and comparison with human lung tissue fragments. Am Rev Respir Dis 1982 1.14
30 Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells. Immunology 1992 1.14
31 Differential regulation of epithelial-derived C-C chemokine expression by IL-4 and the glucocorticoid budesonide. J Immunol 1999 1.14
32 Inhibition of basophil histamine release by anti-inflammatory steroids. Nature 1981 1.14
33 The role of adhesion molecules in human eosinophil and basophil recruitment. J Allergy Clin Immunol 1994 1.12
34 Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils. J Leukoc Biol 1997 1.12
35 Comparative studies of human basophils and mast cells. Fed Proc 1983 1.11
36 Regulation of human basophil and lung mast cell function by cyclic adenosine monophosphate. J Immunol 1988 1.11
37 Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to non-membrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes, and neutrophils. J Histochem Cytochem 1992 1.10
38 Mast cells, basophils, and eosinophils: distinct but overlapping pathways for recruitment. Immunol Rev 2001 1.10
39 Lipopolysaccharide-induced leukocyte rolling and adhesion in the rat mesenteric microcirculation: regulation by glucocorticoids and role of cytokines. J Immunol 1998 1.09
40 Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation. J Cell Biol 1984 1.07
41 Eosinophil transendothelial migration induced by cytokines. II. Potentiation of eosinophil transendothelial migration by eosinophil-active cytokines. J Immunol 1994 1.07
42 CD44 and CD69 represent different types of cell-surface activation markers for human eosinophils. Am J Respir Cell Mol Biol 1998 1.06
43 Human lung macrophage-derived histamine-releasing activity is due to IgE-dependent factors. J Immunol 1986 1.05
44 Interaction between hyperosmolar and IgE-mediated histamine release from basophils and mast cells. Am Rev Respir Dis 1984 1.05
45 Detection of the chemokine RANTES and endothelial adhesion molecules in nasal polyps. J Allergy Clin Immunol 1996 1.05
46 Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1. Am J Respir Cell Mol Biol 1997 1.03
47 Role of human basophils and mast cells in the pathogenesis of allergic diseases. J Allergy Clin Immunol 1985 1.02
48 Characterization of inflammatory mediator release from purified human lung mast cells. Am Rev Respir Dis 1986 1.01
49 Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen. J Immunol 1991 1.01
50 Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects. J Allergy Clin Immunol 2001 1.00
51 Flow cytometric methods for the analysis of human basophil surface antigens and viability. J Immunol Methods 1989 1.00
52 Glucocorticosteroid inhibition of cytokine production: relevance to antiallergic actions. J Allergy Clin Immunol 1996 0.99
53 Interleukin-1 is released at sites of human cutaneous allergic reactions. J Allergy Clin Immunol 1990 0.98
54 Inhibition of basophil histamine release by anti-inflammatory steroids. II. Studies on the mechanism of action. J Immunol 1982 0.98
55 Human lung macrophages enhance and inhibit lymphocyte proliferation. J Immunol 1984 0.98
56 Modulation of MHC class II expression in human cells by dexamethasone. Cell Immunol 1995 0.98
57 Differential synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine and platelet-activating factor by human inflammatory cells. J Immunol 1991 0.97
58 Adherence of human basophils to cultured umbilical vein endothelial cells. J Clin Invest 1988 0.96
59 Double-stranded RNA activates RANTES gene transcription through co-operation of nuclear factor-kappaB and interferon regulatory factors in human airway epithelial cells. Clin Exp Allergy 2004 0.96
60 Preliminary identification and role of phosphodiesterase isozymes in human basophils. J Immunol 1992 0.95
61 Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge. J Clin Invest 1987 0.95
62 Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. I. Characterization of the response. J Immunol 1981 0.95
63 Inhibition of T cell-mediated cytotoxicity by anti-inflammatory steroids. J Immunol 1984 0.95
64 Interleukin 1 production by human lung tissue. II. Inhibition by anti-inflammatory steroids. J Immunol 1987 0.94
65 Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro. J Med Genet 2004 0.94
66 Expression of a functional laminin receptor (alpha 6 beta 1, very late activation antigen-6) on human eosinophils. Blood 1993 0.94
67 Dexamethasone does not inhibit the release of mediators from human mast cells residing in airway, intestine, or skin. Am Rev Respir Dis 1989 0.94
68 Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not non-eosinophilic, chronic rhinosinusitis with nasal polyps. Clin Exp Allergy 2014 0.93
69 Differential regulation of human basophil and lung mast cell function by adenosine. J Pharmacol Exp Ther 1991 0.93
70 Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids. Am J Respir Cell Mol Biol 1999 0.93
71 Qualitative differences between dimeric and trimeric stimulation of human basophils. J Immunol 1983 0.93
72 The mechanisms of antiinflammatory steroid action in allergic diseases. Annu Rev Pharmacol Toxicol 1985 0.92
73 Immunoglobulin E-mediated degranulation of isolated human lung mast cells. Lab Invest 1985 0.91
74 IL-3 augments adhesiveness for endothelium and CD11b expression in human basophils but not neutrophils. J Immunol 1990 0.91
75 Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis. Clin Exp Allergy 2015 0.90
76 Pathogenesis of nasal polyposis. Clin Exp Allergy 2015 0.90
77 Human endothelial cells prolong eosinophil survival. Regulation by cytokines and glucocorticoids. J Immunol 1989 0.90
78 Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes. Cell Death Dis 2013 0.89
79 Human mast cells use conservation and condensation mechanisms during recovery from degranulation. In vitro studies with mast cells purified from human lungs. Lab Invest 1986 0.89
80 Phenotypic analysis of alveolar macrophages and monocytes in allergic airway inflammation. I. Evidence for activation of alveolar macrophages, but not peripheral blood monocytes, in subjects with allergic rhinitis and asthma. Am J Respir Crit Care Med 1997 0.89
81 Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps. Allergy 2011 0.88
82 Cutaneous injection of RANTES causes eosinophil recruitment: comparison of nonallergic and allergic human subjects. J Immunol 1997 0.88
83 Codeine induces human mast cell chemokine and cytokine production: involvement of G-protein activation. Allergy 2007 0.88
84 The pharmacologic modulation of the release of arachidonic acid metabolites from purified human lung mast cells. Am Rev Respir Dis 1985 0.88
85 Leukotriene B4 as a mediator of early and late reactions to antigen in humans: the effect of systemic glucocorticoid treatment in vivo. J Allergy Clin Immunol 1989 0.88
86 Protection by dexamethasone of the functional desensitization to beta 2-adrenoceptor-mediated responses in human lung mast cells. Br J Pharmacol 1997 0.87
87 Selective inhibition of arachidonic acid metabolite release from human lung tissue by antiinflammatory steroids. J Immunol 1986 0.87
88 Functional desensitization of beta agonist responses in human lung mast cells. Am J Respir Cell Mol Biol 1995 0.86
89 Human mast cells synthesize new granules during recovery from degranulation. In vitro studies with mast cells purified from human lungs. Blood 1988 0.86
90 Comparison of human eosinophil and neutrophil ligands for P-selectin: ligands for P-selectin differ from those for E-selectin. Am J Respir Cell Mol Biol 1995 0.86
91 The epithelium as a target of glucocorticoid action in the treatment of asthma. Am J Respir Crit Care Med 1996 0.85
92 The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma. Am J Respir Crit Care Med 2000 0.84
93 Morphologic mast cell cycles. Cell Immunol 1987 0.84
94 Lipoxygenase products of arachidonic acid: role in modulation of IgE-induced histamine release. Adv Prostaglandin Thromboxane Leukot Res 1982 0.84
95 Regulation of the action of hydrocortisone in airway epithelial cells by 11beta-hydroxysteroid dehydrogenase. Am J Respir Cell Mol Biol 1999 0.84
96 Generation of leukotriene B4 by human lung fragments and purified human lung mast cells. Am Rev Respir Dis 1988 0.84
97 GM-CSF regulates human eosinophil responses to F-Met peptide and platelet activating factor. J Immunol 1993 0.83
98 Production of granulocyte/macrophage colony-stimulating factor in human airways during allergen-induced late-phase reactions in atopic subjects. Lymphokine Cytokine Res 1992 0.83
99 Inflammatory mediators and mechanisms of release from purified human basophils and mast cells. J Allergy Clin Immunol 1984 0.83
100 Appearance of granulocyte-macrophage colony-stimulating factor activity at allergen-challenged cutaneous late-phase reaction sites. J Immunol 1993 0.83
101 Transforming growth factor-β stimulates the expression of eotaxin/CC chemokine ligand 11 and its promoter activity through binding site for nuclear factor-κβ in airway smooth muscle cells. Clin Exp Allergy 2010 0.82
102 Migration of eosinophils across endothelial cell monolayers: interactions among IL-5, endothelial-activating cytokines, and C-C chemokines. J Immunol 2000 0.82
103 Mediator release from human basophils and mast cells from lung and intestinal mucosa. Int Arch Allergy Appl Immunol 1985 0.82
104 Identification of novel inducible genes in airway epithelium. Am J Respir Cell Mol Biol 1997 0.81
105 Purified human basophils and mast cells: current concepts of mediator release. Eur J Respir Dis Suppl 1983 0.81
106 Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. II. Interaction with other stimuli. J Immunol 1982 0.81
107 Expression of interleukin-16 by human epithelial cells. Inhibition by dexamethasone. Am J Respir Cell Mol Biol 1999 0.80
108 The pathophysiology of human mast cells. In vitro and in vivo function. Am Rev Respir Dis 1987 0.79
109 Endogenous glucocorticoids and antigen-induced acute and late phase pulmonary responses. Clin Exp Allergy 2000 0.79
110 Inhibition by adenosine of histamine and leukotriene release from human basophils. Biochem Pharmacol 1989 0.78
111 Induction of tolerance to a soluble antigen following irradiation and bone marrow reconstitution. Int Arch Allergy Appl Immunol 1982 0.78
112 Simultaneous quantitation of endogenous levels of cortisone and cortisol in human nasal and bronchoalveolar lavage fluids and plasma via gas chromatography-negative ion chemical ionization mass spectrometry. Anal Biochem 1994 0.78
113 The pharmacologic control of mediator release from human basophils and mast cells. Respiration 1986 0.78
114 Functional regulation of beta 1 integrins on human eosinophils by divalent cations and cytokines. Am J Respir Cell Mol Biol 1996 0.78
115 Effects of prostaglandin synthesis inhibition on the immune response. Immunopharmacology 1981 0.78
116 Dexamethasone inhibits the antigen-induced contractile activity and release of inflammatory mediators in isolated guinea pig lung tissue. Am Rev Respir Dis 1987 0.77
117 The role of prostaglandin D2 in IgE-mediated reactions in man. Trans Assoc Am Physicians 1982 0.77
118 An in vitro comparison of commonly used topical glucocorticoid preparations. J Allergy Clin Immunol 1999 0.77
119 Characterization of platelet-activating factor synthesized by normal and granulocyte-macrophage colony-stimulating factor-primed human eosinophils. Immunology 1992 0.77
120 Mast cells and mast cell mediators in models of airway disease. Prog Clin Biol Res 1985 0.77
121 Antiinflammatory steroids inhibit granulocyte/macrophage colony-stimulating factor production by human lung tissue. Lung 1994 0.77
122 Inhibition of human basophil leukotriene release by antiinflammatory steroids. Int Arch Allergy Appl Immunol 1985 0.77
123 RNA is closely associated with human mast cell secretory granules, suggesting a role(s) for granules in synthetic processes. J Histochem Cytochem 2000 0.77
124 Application of a flow cytometric method using autofluorescence and a tandem fluorescent dye to analyze human alveolar macrophage surface markers. J Immunol Methods 1994 0.77
125 IgE-dependent regulation of human basophil adherence to vascular endothelium. J Immunol 1989 0.76
126 Function and expression of adhesion molecules on human basophils. J Allergy Clin Immunol 1994 0.76
127 Assessment of signal transducer and activator of transcription 6 as a target of glucocorticoid action in human airway epithelial cells. Clin Exp Allergy 2004 0.76
128 The effects of the potent glucocorticoid budesonide on adhesion of eosinophils to human vascular endothelial cells and on endothelial expression of adhesion molecules. J Pharmacol Exp Ther 1993 0.76
129 Is leukotriene B4 an important mediator in human IgE-mediated allergic reactions? Am Rev Respir Dis 1987 0.76
130 The anti-inflammatory profile of inhaled corticosteroids: biopsy studies in asthmatic patients. Respir Med 2000 0.76
131 Interleukin 1 production by human lung tissue. I. Identification and characterization. J Immunol 1987 0.76
132 Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo. J Immunol 1991 0.75
133 IgE-mediated leukotriene release in vitro and in vivo. Trans Assoc Am Physicians 1984 0.75
134 Analysis of mast cell activation using diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Int Arch Allergy Immunol 1995 0.75
135 How do steroids work? Am J Respir Crit Care Med 1996 0.75
136 Specificity of mouse leukocyte binding to insolubilized histamine. Proc West Pharmacol Soc 1979 0.75
137 Diamine oxidase-gold ultrastructural localization of histamine in isolated human lung mast cells stimulated to undergo anaphylactic degranulation and recovery in vitro. J Leukoc Biol 1996 0.75
138 Radioimmunoassay for fentanyl. Methods Enzymol 1982 0.75
139 The effect of endotoxin on immediate hypersensitivity as assessed by puncture skin testing. Ann Allergy 1987 0.75
140 Measurement of low picomolar levels of triamcinolone acetonide in human bronchoalveolar lavage fluid by gas chromatography-electron-capture negative-ion mass spectrometry. Anal Biochem 2001 0.75
141 Studies with purified human basophils and mast cells. Monogr Allergy 1983 0.75
142 Human mast cells and basophils--structure, function, pharmacology, and biochemistry. Clin Rev Allergy 1983 0.75
143 In vitro resistance to dexamethasone of basophils from patients receiving long-term steroid therapy. Am Rev Respir Dis 1985 0.75
144 Wy-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy)phenyl]membrane sulfonamide), an orally active leukotriene antagonist: effects on arachidonic acid metabolism in various inflammatory cells. Eur J Pharmacol 1988 0.75
145 Diamine oxidase-gold labels histamine in human mast-cell granules: a new enzyme-affinity ultrastructural method. J Histochem Cytochem 1993 0.75
146 Inhibition of lytic programming by pharmacologic agents. Ann N Y Acad Sci 1988 0.75
147 Immunochemical studies on the enkephalins and endorphins. Proc West Pharmacol Soc 1979 0.75