Hepatic artery ligation with and without portal infusion of 5-FU. A randomized study in patients with unresectable liver metastases from colorectal carcinoma. The E.O.R.T.C. Gastrointestinal Cancer Cooperative Group (G.I. Group).

Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis. Colorectal Cancer Collaborative Group. BMJ (2000) 3.09

Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg (1999) 6.93

The effect of debulking surgery after induction chemotherapy on the prognosis in advanced epithelial ovarian cancer. Gynecological Cancer Cooperative Group of the European Organization for Research and Treatment of Cancer. N Engl J Med (1995) 4.75

Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg (1997) 4.47

Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group. J Clin Oncol (2000) 4.25

Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet (1998) 4.16

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol (1998) 3.79

Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group. J Clin Oncol (1991) 3.25

Center for Birth Defects Information Services. Birth Defects Orig Artic Ser (1980) 3.09

Fraud in medical research: an international survey of biostatisticians. ISCB Subcommittee on Fraud. Control Clin Trials (2000) 2.67

Leptin secretion and leptin receptor in the human stomach. Gut (2000) 2.46

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: an updated meta-analysis. J Clin Oncol (2004) 2.24

Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am J Pathol (1997) 2.19

Gastrinomas in the duodenums of patients with multiple endocrine neoplasia type 1 and the Zollinger-Ellison syndrome. N Engl J Med (1990) 2.12

Morbidity of thyroid surgery. Am J Surg (1998) 2.10

A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer. Ann Oncol (2005) 2.09

Transvaginal removal of gallbladders with large stones after laparoscopic cholecystectomy. Surg Laparosc Endosc (1993) 2.07

Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. J Clin Oncol (1998) 2.05

Laparoscopic resection of gastric gastrointestinal stromal tumors (GIST) is safe and effective, irrespective of tumor size. Surg Endosc (2012) 2.04

[Impact of obesity on postoperative results of elective laparoscopic colectomy in sigmoid diverticulitis: a prospective study]. Ann Chir (2001) 2.03

Hydroxyurea for treatment of severe sickle cell anemia: a pediatric clinical trial. Blood (1996) 2.01

Pattern of cancer risk in persons with AIDS in Italy in the HAART era. Br J Cancer (2009) 1.95

Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. J Natl Cancer Inst (1996) 1.93

Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organization for Research and Treatment of Cancer (EORTC). Ann Surg (1988) 1.87

Changing patterns of cancer incidence in the early- and late-HAART periods: the Swiss HIV Cohort Study. Br J Cancer (2010) 1.86

Adjuvant treatment of stage I lung cancer with high-dose vitamin A. J Clin Oncol (1993) 1.84

Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy. Pharmacogenomics J (2010) 1.75

Determinants of recurrence after sigmoid resection for uncomplicated diverticulitis. Dis Colon Rectum (2003) 1.70

Indexes of surgical quality in gastric cancer surgery: experience of an Italian network. Ann Surg Oncol (2009) 1.66

Third molar root development in relation to chronological age: a large sample sized retrospective study. Forensic Sci Int (2003) 1.58

Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: data from 12,676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803. Eur J Cancer (2011) 1.57

Immunocytochemical markers in stage I lung cancer: relevance to prognosis. J Clin Oncol (1997) 1.55

Progression-free survival as surrogate and as true end point: insights from the breast and colorectal cancer literature. Ann Oncol (2009) 1.54

Evaluation of clinical efficacy of new medical treatments in advanced colorectal cancer. Results of a workshop organized by the EORTC GITCCG. European Organization for Research and Treatment of Cancer. Gastrointestinal Tract Cancer Cooperative Group. Tumori (1998) 1.54

Dose-dense adjuvant chemotherapy in node-positive breast cancer: docetaxel followed by epirubicin/cyclophosphamide (T/EC), or the reverse sequence (EC/T), every 2 weeks, versus docetaxel, epirubicin and cyclophosphamide (TEC) every 3 weeks. AERO B03 randomized phase II study. Ann Oncol (2006) 1.54

Neuroendocrine tumors of the pancreas. Surg Endosc (2003) 1.53

Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial). Ann Oncol (2003) 1.52

Endoscopic sphincterotomy prior to laparoscopic cholecystectomy for the treatment of cholelithiasis. Surg Endosc (2003) 1.51

Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience. Ann Surg (1996) 1.51

The trials of Dr. Bernard Fisher: a European perspective on an American episode. Control Clin Trials (1997) 1.49

Cell renewal in the human rectum. In vitro autoradiographic study on active ulcerative colitis. Gastroenterology (1970) 1.49

Should there be mass screening using faecal occult blood tests for colorectal cancer? Eur J Cancer (1998) 1.48

Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial. European Organisation for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group, the Gruppo Interdisciplinare Valutazione Interventi in Oncologia, and the Japanese Foundation for Cancer Research. Lancet (1998) 1.46

Biliary elimination of mezlocillin: an experimental and clinical study. Antimicrob Agents Chemother (1980) 1.46

Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. Ann Oncol (2007) 1.44

Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia (1998) 1.44

Management of cutaneous melanoma M0: state of the art and trends. Eur J Cancer (1997) 1.43

Coma due to water intoxication in beer drinkers. Lancet (1971) 1.42

Endogenous hypergastrinaemia does not promote growth of colonic mucosa or of a transplanted colon adenocarcinoma in rats. Eur J Gastroenterol Hepatol (1998) 1.42

Pancreatic metastasis of renal cell carcinoma: presentation, treatment and survival. J Urol (2001) 1.42

Lung cancer in the Swiss HIV Cohort Study: role of smoking, immunodeficiency and pulmonary infection. Br J Cancer (2012) 1.41

Reproducibility of monoamine metabolite measurements in human cerebrospinal fluid. Acta Neurol Scand (1990) 1.41

Surgical management of BANS malignant melanoma. Surgery (1991) 1.40

Gallstone ileus. JBR-BTR (2010) 1.40

The value of preoperative radiotherapy in esophageal cancer: results of a study of the E.O.R.T.C. World J Surg (1987) 1.40

Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma: final results of a GERCOR multicenter phase II study. J Clin Oncol (2002) 1.39

Limb-sparing treatment for soft tissue sarcomas: influence of prognostic factors. J Surg Oncol (1996) 1.39

[Pseudomyxoma peritonei. Apropos of 19 cases]. J Chir (Paris) (1993) 1.38

Oxaliplatin clinical activity: a review. Crit Rev Oncol Hematol (2000) 1.35

[The problem of therapeutic efficacy indices. 3. Comparison of the indices and their use]. Therapie (2000) 1.34

Prognostic factors affecting long term outcome after liver resection for hepatocellular carcinoma: results in a series of 100 Italian patients. Cancer (1998) 1.34

Interleukin-6 blood level is associated with circulating carcinoembryonic antigen and prognosis in patients with colorectal cancer. Ann Surg Oncol (2000) 1.33

Cell renewal in familial polyposis: comparison between polyps and adjacent healthy mucosa. Gastroenterology (1972) 1.30

Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers. Br J Cancer (2010) 1.30

Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial). Ann Oncol (2009) 1.29

Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists' Group. Br J Cancer (1998) 1.27

Laparoscopic cholecystectomy in acute cholecystitis. A prospective comparative study in patients with acute vs. chronic cholecystitis. Surg Endosc (2000) 1.27

Synchronous carcinoma of the colon and rectum: prognostic and therapeutic implications. Am J Surg (1989) 1.25

An EORTC Gastrointestinal Group evaluation of the combination of sequential methotrexate and 5-fluorouracil, combined with adriamycin in advanced measurable gastric cancer. J Clin Oncol (1986) 1.23

Gastrin stimulates the self-replication rate of enterochromaffinlike cells in the rat stomach. Effects of omeprazole, ranitidine, and gastrin-17 in intact and antrectomized rats. Gastroenterology (1990) 1.23

Late recurrence of a hepatic angiomyolipoma. Eur J Gastroenterol Hepatol (2000) 1.23

Colorectal cancer in patients under 40 years of age. Dis Colon Rectum (1986) 1.23

Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient. Diabetologia (2013) 1.22

Primary cultures of endothelial cells from the human liver sinusoid are permissive for human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1992) 1.21

Final results of a randomized trial on the treatment of rectal cancer with preoperative radiotherapy alone or in combination with 5-fluorouracil, followed by radical surgery. Trial of the European Organization on Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group. Cancer (1984) 1.18

Impact of recent legislative bills regarding clinical research on Italian ethics committee activity. J Med Ethics (2008) 1.18

Instructional multimedia program versus standard lecture: a comparison of two methods for teaching the undergraduate orthodontic curriculum. Eur J Dent Educ (2004) 1.16

Proliferation of enterochromaffinlike cells in omeprazole-treated hypergastrinemic rats. Gastroenterology (1989) 1.16

Adjuvant therapy of poor prognosis colon cancer with levamisole: results of an EORTC double-blind randomized clinical trial. Br J Surg (1989) 1.16

Laparoscopic cholecystectomy in the elderly: a prospective study. Surg Endosc (2000) 1.15

In vitro autoradiographic determination of cell kinetic parameters in adenocarcinomas and adjacent healthy mucosa of the human colon and rectum. Cancer Res (1976) 1.15

Colonic mucosal atrophy induced by a liquid elemental diet in rats. Am J Dig Dis (1977) 1.15

Stimulating effect of gastrin on cell proliferation kinetics in canine fundic mucosa. Gastroenterology (1972) 1.15

[Internal hernia: a rare cause of intestinal obstruction. Apropos of 14 cases]. Ann Chir (1999) 1.14

Dental maturity in Belgian children using Demirjian's method and polynomial functions: new standard curves for forensic and clinical use. J Forensic Odontostomatol (2004) 1.14

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma. Br J Cancer (2004) 1.14

Curative surgery for obstruction from primary left colorectal carcinoma: primary or staged resection? Cochrane Database Syst Rev (2004) 1.14

Assessment by nano-indentation of the hardness and elasticity of the resin-dentin bonding area. J Dent Res (1993) 1.13

Laparoscopic adjustable silicone gastric banding (Lap-Band): how to avoid complications. Obes Surg (1997) 1.13

Phase II study of epirubicin in advanced adenocarcinoma of the pancreas. Eur J Cancer Clin Oncol (1985) 1.12

The prognostic value of N-ratio in patients with gastric cancer: validation in a large, multicenter series. Eur J Surg Oncol (2007) 1.12

Primary anastomosis after intraoperative colonic lavage vs. Hartmann's procedure in generalized peritonitis complicating diverticular disease of the colon. Int J Colorectal Dis (2003) 1.11

Gastrointestinal carcinoid: epidemiological and survival evidence from a large population-based study (n = 25 531). Ann Oncol (2013) 1.11

Phase II trial of vinorelbine in metastatic squamous cell esophageal carcinoma. European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group. J Clin Oncol (1996) 1.10