Little evidence for association of the glaucoma gene MYOC with open-angle glaucoma.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 2976471)

Published in Br J Ophthalmol on May 01, 2010

Authors

Seongsoo Sohn1, Wonhee Hur, Young Ran Choi, Yun Shin Chung, Chang-Seok Ki, Changwon Kee

Author Affiliations

1: Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, South Korea.

Articles cited by this

Identification of a gene that causes primary open angle glaucoma. Science (1997) 8.14

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells. J Biol Chem (1998) 2.13

Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids. Arch Ophthalmol (1996) 1.81

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function. Mol Cell Biol (2001) 1.75

Comparative ocular pressure elevation by medrysone, fluorometholone, and dexamethasone phosphate. Arch Ophthalmol (1980) 1.59

Localization of the stress proteins alpha B-crystallin and trabecular meshwork inducible glucocorticoid response protein in normal and glaucomatous trabecular meshwork. Invest Ophthalmol Vis Sci (1998) 1.29

Variations in the myocilin gene in patients with open-angle glaucoma. Arch Ophthalmol (2002) 1.28

Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment. Invest Ophthalmol Vis Sci (2000) 1.26

Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma. Mol Cell Biol (2004) 1.23

Evaluation of the myocilin (MYOC) glaucoma gene in monkey and human steroid-induced ocular hypertension. Invest Ophthalmol Vis Sci (2001) 1.16

Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments. Invest Ophthalmol Vis Sci (2002) 1.14

Molecular and clinical evaluation of a patient hemizygous for TIGR/MYOC. Arch Ophthalmol (2001) 1.13

Association of a single nucleotide polymorphism in the TIGR/MYOCILIN gene promoter with the severity of primary open-angle glaucoma. Clin Genet (2001) 1.07

[Not Available]. Ann Ocul (Paris) (1954) 1.03

Overexpression and properties of wild-type and Tyr437His mutated myocilin in the eyes of transgenic mice. Invest Ophthalmol Vis Sci (2005) 1.00

Role of MYOC and OPTN sequence variations in Spanish patients with primary open-angle glaucoma. Mol Vis (2007) 0.96

Myocilin gene expression in the trabecular meshwork of rats in a steroid-induced ocular hypertension model. Ophthalmic Res (2005) 0.87

Association of the myocilin mt.1 promoter variant with the worsening of glaucomatous disease over time. Clin Genet (2003) 0.87

Myocilin mt1 promoter polymorphism in Turkish patients with primary open angle glaucoma. Mol Vis (2005) 0.84

mRNA in situ hybridization of TIGR/MYOC in human trabecular meshwork. Invest Ophthalmol Vis Sci (2000) 0.83

Promoter mutations of myocilin gene in Japanese patients with open angle glaucoma including normal tension glaucoma. Br J Ophthalmol (2000) 0.83

Mutations including the promoter region of myocilin/TIGR gene. Eur J Hum Genet (2005) 0.82

Changes in mRNA levels of the Myoc/Tigr gene in the rat eye after experimental elevation of intraocular pressure or optic nerve transection. Invest Ophthalmol Vis Sci (2001) 0.82

Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma. J Glaucoma (2004) 0.81

No evidence of association between GT/CA-repeat polymorphism in the GLC1A gene promoter and primary open-angle or exfoliation glaucoma. Acta Ophthalmol Scand (2002) 0.80

Articles by these authors

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46

Correct use of repeated measures analysis of variance. Korean J Lab Med (2009) 2.45

A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development (2004) 1.92

Whole blood Epstein-Barr virus DNA load as a diagnostic and prognostic surrogate: extranodal natural killer/T-cell lymphoma. Leuk Lymphoma (2009) 1.83

Pseudoexfoliative material on the IOL surface and development of glaucoma after cataract surgery in patients with pseudoexfoliation syndrome. J Cataract Refract Surg (2007) 1.75

Evaluation of Cobas TaqMan MTB PCR for detection of Mycobacterium tuberculosis. J Clin Microbiol (2010) 1.74

Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells. Biochem Biophys Res Commun (2003) 1.72

GATA2 functions at multiple steps in hemangioblast development and differentiation. Development (2006) 1.69

Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. Am J Respir Crit Care Med (2015) 1.68

Impact of MET amplification on gastric cancer: possible roles as a novel prognostic marker and a potential therapeutic target. Oncol Rep (2011) 1.66

Novel interleukin 1beta polymorphism increased the risk of gastric cancer in a Korean population. J Gastroenterol (2004) 1.65

Comparison of visual field progression between relatively low and high intraocular pressure groups in normal tension glaucoma patients. J Glaucoma (2014) 1.58

The effect of cataract extraction on the contractility of ciliary muscle. Am J Ophthalmol (2008) 1.45

Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5). Am J Hum Genet (2007) 1.42

Impact of epidermal growth factor receptor (EGFR) kinase mutations, EGFR gene amplifications, and KRAS mutations on survival of pancreatic adenocarcinoma. Cancer (2007) 1.42

The proportion of uniparental disomy is increased in Prader-Willi syndrome due to an advanced maternal childbearing age in Korea. J Hum Genet (2013) 1.42

A novel exon 3 mutation (P66S) in the SOD1 gene in familial ALS. Can J Neurol Sci (2012) 1.40

[In vitro culture of hepatitis C virus (HCV) using immortalized hepatocyte]. Korean J Gastroenterol (2008) 1.39

Rapid detection and identification of 12 respiratory viruses using a dual priming oligonucleotide system-based multiplex PCR assay. J Virol Methods (2008) 1.37

CD133+ liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma. Cancer Lett (2011) 1.33

Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. Antimicrob Agents Chemother (2006) 1.31

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One (2013) 1.23

Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea. Cancer Lett (2005) 1.21

HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1. Exp Mol Med (2005) 1.20

Polymorphism near the IL28B gene in Korean hepatitis C virus-infected patients treated with peg-interferon plus ribavirin. J Clin Virol (2011) 1.13

BRAFV600E mutation analysis in fine-needle aspiration cytology specimens for evaluation of thyroid nodule: a large series in a BRAFV600E-prevalent population. J Clin Endocrinol Metab (2010) 1.13

Mutant enrichment with 3'-modified oligonucleotides a practical PCR method for detecting trace mutant DNAs. J Mol Diagn (2011) 1.12

Clinical implication of highly sensitive detection of the BRAF V600E mutation in fine-needle aspirations of thyroid nodules: a comparative analysis of three molecular assays in 4585 consecutive cases in a BRAF V600E mutation-prevalent area. J Clin Endocrinol Metab (2012) 1.12

Comparison of the Xpert MTB/RIF and Cobas TaqMan MTB assays for detection of Mycobacterium tuberculosis in respiratory specimens. J Clin Microbiol (2013) 1.11

Reform of medical education in Korea. Med Teach (2010) 1.10

A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J Biol Chem (2010) 1.09

Screening of the SOD1, FUS, TARDBP, ANG, and OPTN mutations in Korean patients with familial and sporadic ALS. Neurobiol Aging (2012) 1.07

Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract. Mol Cell Biol (2002) 1.07

Ultrasonic biomicroscopic evaluation of cyclodialysis before and after direct cyclopexy. Arch Ophthalmol (2008) 1.07

Mutation analysis of the GNE gene in Korean patients with distal myopathy with rimmed vacuoles. J Hum Genet (2005) 1.06

Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis. Tuberculosis (Edinb) (2007) 1.05

Klebsiella pneumoniae co-producing NDM-5 and OXA-181 carbapenemases, South Korea. Emerg Infect Dis (2015) 1.05

Silencing of 14-3-3ζ over-expression in hepatocellular carcinoma inhibits tumor growth and enhances chemosensitivity to cis-diammined dichloridoplatium. Cancer Lett (2011) 1.05

Expression of wild-type and truncated myocilins in trabecular meshwork cells: their subcellular localizations and cytotoxicities. Invest Ophthalmol Vis Sci (2002) 1.04

Evaluation of the GenBank, EzTaxon, and BIBI services for molecular identification of clinical blood culture isolates that were unidentifiable or misidentified by conventional methods. J Clin Microbiol (2012) 1.03

NRAMP1 gene polymorphism and susceptibility to nontuberculous mycobacterial lung diseases. Chest (2005) 1.03

Identification of clinical mold isolates by sequence analysis of the internal transcribed spacer region, ribosomal large-subunit D1/D2, and β-tubulin. Ann Lab Med (2012) 1.03

Evaluation of PCR-based screening for vancomycin-resistant enterococci compared with a chromogenic agar-based culture method. J Med Microbiol (2011) 1.03

Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population. Haematologica (2013) 1.02

Mutation analysis of SPG4 and SPG3A genes and its implication in molecular diagnosis of Korean patients with hereditary spastic paraplegia. Arch Neurol (2005) 1.00

Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort. Invest Ophthalmol Vis Sci (2010) 1.00

Distribution of nontuberculous mycobacteria by multigene sequence-based typing and clinical significance of isolated strains. J Clin Microbiol (2014) 0.98

Acquired Gitelman syndrome in a patient with primary Sjögren syndrome. Am J Kidney Dis (2008) 0.97

Report of a Korean patient with cystic fibrosis, carrying Q98R and Q220X mutations in the CFTR gene. J Korean Med Sci (2006) 0.97

Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced non-small cell lung cancer? Clin Cancer Res (2008) 0.97

Selective COX-2 inhibitor, NS-398, suppresses cellular proliferation in human hepatocellular carcinoma cell lines via cell cycle arrest. World J Gastroenterol (2007) 0.96

A comparison of the Ghent and revised Ghent nosologies for the diagnosis of Marfan syndrome in an adult Korean population. Am J Med Genet A (2011) 0.96

Functional identification of the pro-apoptotic effector domain in human Sox4. Biochem Biophys Res Commun (2004) 0.95

Identification of flotillin-1 as a protein interacting with myocilin: implications for the pathogenesis of primary open-angle glaucoma. Biochem Biophys Res Commun (2005) 0.94

Influence of the extent of myopia on the progression of normal-tension glaucoma. Am J Ophthalmol (2010) 0.93

Identification of an Arg35X mutation in the PDCD10 gene in a patient with cerebral and multiple spinal cavernous malformations. J Neurol Sci (2007) 0.93

First case of Bartonella quintana endocarditis in Korea. J Korean Med Sci (2012) 0.93

Complete sequencing of a genetic polymorphism in NAT2 in the Korean population. Clin Chem (2002) 0.93

SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15). PLoS One (2013) 0.92

Molecular screening of the TSH receptor (TSHR) and thyroid peroxidase (TPO) genes in Korean patients with nonsyndromic congenital hypothyroidism. Clin Endocrinol (Oxf) (2011) 0.92

Pediatric-onset dystonia associated with bilateral striatal necrosis and G14459A mutation in a Korean family: a case report. J Korean Med Sci (2009) 0.92

The distribution of intraocular pressure in urban and in rural populations: the Namil study in South Korea. Am J Ophthalmol (2012) 0.92

Streptococcus suis meningitis with bilateral sensorineural hearing loss. Korean J Lab Med (2011) 0.91

Clinical evaluation of micro-scale chip-based PCR system for rapid detection of hepatitis B virus. Biosens Bioelectron (2005) 0.91

Large diurnal variation of intraocular pressure despite maximal medical treatment in juvenile open angle glaucoma. J Glaucoma (2007) 0.90

The effect of bevacizumab on the outcome of trabeculectomy with 5-Fluorouracil. J Ocul Pharmacol Ther (2013) 0.90

Clinical features and genetic analysis of Korean patients with Loeys-Dietz syndrome. J Hum Genet (2011) 0.90

Standardization of terminology in laboratory medicine II. J Korean Med Sci (2008) 0.90

Ischemia-modified albumin is a highly sensitive serum marker of transient myocardial ischemia induced by coronary vasospasm. Coron Artery Dis (2007) 0.90

Identification of PSEN1 and APP gene mutations in Korean patients with early-onset Alzheimer's disease. J Korean Med Sci (2008) 0.90

High frequency of microsatellite instability in intestinal-type gastric cancer in Korean patients. Korean J Intern Med (2005) 0.90

Optical coherence tomographic findings of crystal deposits in the lens and cornea in Bietti crystalline corneoretinopathy associated with mutation in the CYP4V2 gene. Jpn J Ophthalmol (2013) 0.89

Mutation spectrum of CYP1B1 and MYOC genes in Korean patients with primary congenital glaucoma. Mol Vis (2011) 0.89

Medical education in Korea: the e-learning consortium. Med Teach (2009) 0.89

Identification of proteolipid protein 1 gene duplication by multiplex ligation-dependent probe amplification: first report of genetically confirmed family of Pelizaeus-Merzbacher disease in Korea. J Korean Med Sci (2008) 0.89

Evaluation of peripapillary choroidal thickness in unilateral normal-tension glaucoma. Jpn J Ophthalmol (2013) 0.89

Beneficial effect of metronomic chemotherapy on tumor suppression and survival in a rat model of hepatocellular carcinoma with liver cirrhosis. Cancer Chemother Pharmacol (2009) 0.88

Estimation of carrier frequencies of six autosomal-recessive Mendelian disorders in the Korean population. J Hum Genet (2011) 0.88

Clinical features and gene analysis in Korean patients with early-onset Parkinson disease. Arch Neurol (2006) 0.88

Noninvasive predictors of nonalcoholic steatohepatitis in Korean patients with histologically proven nonalcoholic fatty liver disease. Clin Mol Hepatol (2013) 0.87

Bioimaging for targeted delivery of hyaluronic Acid derivatives to the livers in cirrhotic mice using quantum dots. ACS Nano (2010) 0.87

Heterogeneous spectrum of CFTR gene mutations in Korean patients with cystic fibrosis. Korean J Lab Med (2011) 0.87

Clinical, pathological, and genetic analysis of a Korean family with thoracic aortic aneurysms and dissections carrying a novel Asp26Tyr mutation. Ann Clin Lab Sci (2010) 0.87

Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex. J Biol Chem (2012) 0.87

Mycobacterial infection after intravesical bacillus Calmette-Guërin treatment for bladder cancer: a case report. Korean J Lab Med (2011) 0.87

Novel mutation in the HSN2 gene in a Korean patient with hereditary sensory and autonomic neuropathy type 2. J Hum Genet (2006) 0.87

A novel point mutation in PMP22 gene associated with a familial case of Charcot-Marie-Tooth disease type 1A with sensorineural deafness. Neuromuscul Disord (2004) 0.86

Hepatitis C virus (HCV) genotyping by annealing reverse transcription-PCR products with genotype-specific capture probes. J Microbiol (2008) 0.86

GSTM1, GSTT1 and GSTP1 polymorphisms in the Korean population. J Korean Med Sci (2005) 0.86

Familial Xp22.33-Xp22.12 deletion delineated by chromosomal microarray analysis causes proportionate short stature. Am J Med Genet A (2012) 0.86

The effect of surface area expansion with pericardial membrane (preclude) in Ahmed glaucoma valve implant surgery. J Glaucoma (2004) 0.86

Novel nonsense GNAS mutation in a 14-month-old boy with plate-like osteoma cutis and medulloblastoma. J Dermatol (2014) 0.86

The usefulness of multidetector computed tomographic angiography for the diagnosis of Marfan syndrome by Ghent criteria. Int J Cardiovasc Imaging (2011) 0.86

Clinical and genetic analysis of HLXB9 gene in Korean patients with Currarino syndrome. J Hum Genet (2007) 0.86

Number of mutations within CTL-defined epitopes of the hepatitis B Virus (HBV) core region is associated with HBV disease progression. J Med Virol (2011) 0.85