Novel vaccine prime and selective BCG boost: a new tuberculosis vaccine strategy for infants of HIV-infected mothers.

PubWeight™: 0.80‹?›

🔗 View Article (PMID 20470797)

Published in Vaccine on May 14, 2010

Authors

Mark Hatherill, Hassan Mahomed, Willem Hanekom

Articles by these authors

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial. Lancet (2013) 8.18

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis (2012) 4.60

International study of temperature, heat and urban mortality: the 'ISOTHURM' project. Int J Epidemiol (2008) 4.13

Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J Immunol (2008) 3.19

Immunological biomarkers of tuberculosis. Nat Rev Immunol (2011) 2.88

Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns. Am J Respir Crit Care Med (2010) 2.64

The utility of an interferon gamma release assay for diagnosis of latent tuberculosis infection and disease in children: a systematic review and meta-analysis. Pediatr Infect Dis J (2011) 2.47

High-dose rifapentine with moxifloxacin for pulmonary tuberculosis. N Engl J Med (2014) 2.42

Predictive value of recent QuantiFERON conversion for tuberculosis disease in adolescents. Am J Respir Crit Care Med (2012) 2.32

Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells. Eur J Immunol (2010) 2.25

Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants. J Infect Dis (2011) 2.24

Efficacy of percutaneous versus intradermal BCG in the prevention of tuberculosis in South African infants: randomised trial. BMJ (2008) 2.17

Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load. J Immunol (2011) 2.07

Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa. J Infect Dis (2008) 2.05

The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults. Am J Respir Crit Care Med (2010) 2.03

Structured approaches for the screening and diagnosis of childhood tuberculosis in a high prevalence region of South Africa. Bull World Health Organ (2009) 1.62

Pediatric intensive care in South Africa: an account of making optimum use of limited resources at the Red Cross War Memorial Children's Hospital*. Pediatr Crit Care Med (2014) 1.48

The tuberculin skin test versus QuantiFERON TB Gold® in predicting tuberculosis disease in an adolescent cohort study in South Africa. PLoS One (2011) 1.42

Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG. Tuberculosis (Edinb) (2013) 1.34

Induction and regulation of T-cell immunity by the novel tuberculosis vaccine M72/AS01 in South African adults. Am J Respir Crit Care Med (2013) 1.31

Evaluation of the quality of informed consent in a vaccine field trial in a developing country setting. BMC Med Ethics (2008) 1.27

Consensus statement on diagnostic end points for infant tuberculosis vaccine trials. Clin Infect Dis (2011) 1.25

Comparison of T-SPOT.TB assay and tuberculin skin test for the evaluation of young children at high risk for tuberculosis in a community setting. Pediatrics (2009) 1.23

TB incidence in an adolescent cohort in South Africa. PLoS One (2013) 1.22

Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tract. Immunology (2009) 1.21

Randomized trial of type 1 and type 3 oral monovalent poliovirus vaccines in newborns in Africa. J Infect Dis (2011) 1.17

Mycobacterium tuberculosis-specific CD8+ T cells are functionally and phenotypically different between latent infection and active disease. Eur J Immunol (2013) 1.12

'Communicate to vaccinate' (COMMVAC). building evidence for improving communication about childhood vaccinations in low- and middle-income countries: protocol for a programme of research. Implement Sci (2011) 1.12

Childhood tuberculosis: old and new vaccines. Paediatr Respir Rev (2007) 1.10

A phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis-infected adults. Am J Respir Crit Care Med (2012) 1.09

The dynamics of QuantiFERON-TB gold in-tube conversion and reversion in a cohort of South African adolescents. Am J Respir Crit Care Med (2015) 1.08

Immune activation in the female genital tract during HIV infection predicts mucosal CD4 depletion and HIV shedding. J Infect Dis (2011) 1.06

Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease. Vaccine (2010) 1.03

Moxifloxacin population pharmacokinetics in patients with pulmonary tuberculosis and the effect of intermittent high-dose rifapentine. Antimicrob Agents Chemother (2012) 0.99

HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis. Eur J Immunol (2012) 0.97

Prospects for a new, safer and more effective TB vaccine. Paediatr Respir Rev (2010) 0.94

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. PLoS One (2013) 0.94

Time to symptom resolution in young children treated for pulmonary tuberculosis. Pediatr Infect Dis J (2014) 0.92

Distribution of brain infarction in children with tuberculous meningitis and correlation with outcome score at 6 months. Pediatr Radiol (2006) 0.91

Dose-dependent immune response to Mycobacterium bovis BCG vaccination in neonates. Clin Vaccine Immunol (2006) 0.90

Detection and treatment of subclinical tuberculosis. Tuberculosis (Edinb) (2012) 0.89

Comparison of polyclonal expansion methods to improve the recovery of cervical cytobrush-derived T cells from the female genital tract of HIV-infected women. J Immunol Methods (2010) 0.89

Effect of isoniazid therapy for latent TB infection on QuantiFERON-TB gold in-tube responses in adults with positive tuberculin skin test results in a high TB incidence area: a controlled study. Chest (2014) 0.89

Isolation of non-tuberculous mycobacteria in children investigated for pulmonary tuberculosis. PLoS One (2006) 0.89

Hospital-acquired hyponatremia is associated with excessive administration of intravenous maintenance fluid. Pediatrics (2004) 0.88

Determining causes of mortality in children enrolled in a vaccine field trial in a rural area in the Western Cape Province of South Africa. J Paediatr Child Health (2007) 0.88

Phenotypic variability in childhood TB: implications for diagnostic endpoints in tuberculosis vaccine trials. Vaccine (2011) 0.87

Knowledge and acceptability of patient-specific infection control measures for pulmonary tuberculosis. Am J Infect Control (2013) 0.84

Making COD statistics useful for public health at local level in the city of Cape Town: utilidad para la salud pública a nivel local en Ciudad del Cabo. Bull World Health Organ (2006) 0.84

Developing vaccinology expertise for Africa: six years and counting. Vaccine (2011) 0.84

Screening for TB in high school adolescents in a high burden setting in South Africa. Tuberculosis (Edinb) (2013) 0.83

Clinical course of hospitalised children infected with human metapneumovirus and respiratory syncytial virus. J Paediatr Child Health (2006) 0.82

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response. BMC Infect Dis (2014) 0.81

Relationship between fluid management, changes in serum sodium and outcome in hypernatraemia associated with gastroenteritis. J Paediatr Child Health (2007) 0.80

The potential impact of helminth infection on trials of novel tuberculosis vaccines. Vaccine (2009) 0.79

Risk of Disease After Isoniazid Preventive Therapy for Mycobacterium tuberculosis Exposure in Young HIV-uninfected Children. Pediatr Infect Dis J (2015) 0.78

Comparison of mantoux and tine tuberculin skin tests in BCG-vaccinated children investigated for tuberculosis. PLoS One (2009) 0.78

Diagnostic features associated with culture of Mycobacterium tuberculosis among young children in a vaccine trial setting. Pediatr Infect Dis J (2012) 0.78

Moxifloxacin population pharmacokinetics and model-based comparison of efficacy between moxifloxacin and ofloxacin in African patients. Antimicrob Agents Chemother (2013) 0.78

Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function. Eur J Immunol (2013) 0.77

Vaccine-induced immunity in early life. Vaccine (2013) 0.77

Meeting report: The International Conference on Human Immunity to Tuberculosis. Tuberculosis (Edinb) (2012) 0.76

Clinical Testing of Tuberculosis Vaccine Candidates. Microbiol Spectr (2016) 0.76

Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants. Nat Commun (2016) 0.75

The Role of Clinical Symptoms in the Diagnosis of Intrathoracic Tuberculosis in Young Children. Pediatr Infect Dis J (2015) 0.75