Published in J Am Chem Soc on June 16, 2010
Palladium(II)-catalyzed alkene functionalization via nucleopalladation: stereochemical pathways and enantioselective catalytic applications. Chem Rev (2011) 1.76
Advancing the mechanistic understanding of an enantioselective palladium-catalyzed alkene difunctionalization reaction. J Am Chem Soc (2010) 1.42
Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes. J Am Chem Soc (2013) 1.28
Enantioselective Pd(II)-catalyzed aerobic oxidative amidation of alkenes and insights into the role of electronic asymmetry in pyridine-oxazoline ligands. Org Lett (2011) 1.23
A palladium-catalyzed three-component cross-coupling of conjugated dienes or terminal alkenes with vinyl triflates and boronic acids. J Am Chem Soc (2011) 1.17
A visible-light-mediated oxidative C-N bond formation/aromatization cascade: photocatalytic preparation of N-arylindoles. Angew Chem Int Ed Engl (2012) 1.03
Reconciling the stereochemical course of nucleopalladation with the development of enantioselective wacker-type cyclizations. Angew Chem Int Ed Engl (2012) 1.03
Mechanism and enantioselectivity in palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones: insights from computation and experiment. J Am Chem Soc (2013) 1.02
Applications of ortho-quinone methide intermediates in catalysis and asymmetric synthesis. J Org Chem (2011) 1.01
A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations. J Am Chem Soc (2013) 1.01
Palladium-catalyzed 1,1-difunctionalization of ethylene. J Am Chem Soc (2012) 1.01
Copper-catalyzed intramolecular alkene carboetherification: synthesis of fused-ring and bridged-ring tetrahydrofurans. J Am Chem Soc (2012) 1.00
Rhodium(II)-catalyzed enantioselective C-H functionalization of indoles. J Am Chem Soc (2011) 1.00
Nickel-catalyzed cross couplings of benzylic ammonium salts and boronic acids: stereospecific formation of diarylethanes via C-N bond activation. J Am Chem Soc (2012) 1.00
Asymmetric transition metal-catalyzed cross-coupling reactions for the construction of tertiary stereocenters. Tetrahedron (2013) 0.99
Enantioselective addition of boronates to o-quinone methides catalyzed by chiral biphenols. J Am Chem Soc (2012) 0.98
Rhodium-catalyzed synthesis of 2,3-disubstituted indoles from β,β-disubstituted stryryl azides. Angew Chem Int Ed Engl (2011) 0.92
Enantioselective functionalization of radical intermediates in redox catalysis: copper-catalyzed asymmetric oxytrifluoromethylation of alkenes. Angew Chem Int Ed Engl (2013) 0.90
Enantioselective Dehydrogenative Heck Arylations of Trisubstituted Alkenes with Indoles to Construct Quaternary Stereocenters. J Am Chem Soc (2015) 0.89
Palladium-catalyzed hydrofunctionalization of vinyl phenol derivatives with heteroaromatics. Org Lett (2011) 0.88
Stereospecific nickel-catalyzed cross-coupling reactions of alkyl Grignard reagents and identification of selective anti-breast-cancer agents. Angew Chem Int Ed Engl (2014) 0.87
Intercepting Wacker intermediates with arenes: C-H functionalization and dearomatization. Org Lett (2011) 0.86
Enantioselective synthesis of hindered cyclic dialkyl ethers via catalytic oxa-Michael/Michael desymmetrization. Chem Sci (2013) 0.86
A General, Simple Catalyst for Enantiospecific Cross Couplings of Benzylic Ammonium Triflates and Boronic Acids: No Phosphine Ligand Required. Tetrahedron (2014) 0.85
Copper-catalyzed oxytrifluoromethylation of unactivated alkenes. J Am Chem Soc (2012) 0.84
Combined oxypalladation/C-H functionalization: palladium(II)-catalyzed intramolecular oxidative oxyarylation of hydroxyalkenes. Angew Chem Int Ed Engl (2012) 0.84
Palladium(II)-catalyzed enantio- and diastereoselective synthesis of pyrrolidine derivatives. Org Lett (2012) 0.80
Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes. J Am Chem Soc (2015) 0.79
A scalable synthesis of the (S)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole ((S)-t-BuPyOx) ligand. Beilstein J Org Chem (2013) 0.78
Synthesis and Preliminary Biological Study of Bisindolylmethanes Accessed by an Acid-Catalyzed Hydroarylation of Vinylindoles. Tetrahedron (2012) 0.78
Enantioselective copper-catalyzed carboetherification of unactivated alkenes. Angew Chem Int Ed Engl (2014) 0.78
Iridium-Catalyzed Enantioselective Allylic Substitution of Enol Silanes from Vinylogous Esters and Amides. J Am Chem Soc (2015) 0.76
Diaryl and heteroaryl sulfides: synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents. J Org Chem (2014) 0.75
Palladium-Catalyzed Enantioselective Intermolecular Coupling of Phenols and Allylic Alcohols. J Am Chem Soc (2016) 0.75
Crystal structure of 3-{5-[3-(4-fluoro-phen-yl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate. Acta Crystallogr E Crystallogr Commun (2016) 0.75
Catalytic functionalization of indoles in a new dimension. Angew Chem Int Ed Engl (2009) 1.61
Palladium-catalyzed enantioselective addition of two distinct nucleophiles across alkenes capable of quinone methide formation. J Am Chem Soc (2009) 1.54
Palladium-catalyzed direct arylation of (hetero)arenes with aryl boronic acids. Angew Chem Int Ed Engl (2008) 1.31
Discovery through total synthesis: a retrospective on the himastatin problem. Chemistry (2001) 1.26
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit. Nat Prod Rep (2005) 1.25
It all began with an error: the nomofungin/communesin story. Angew Chem Int Ed Engl (2008) 1.20
The reaction of derivatives of tryptophan, tryptamine, and other indoles with 2-hydroxy-5-nitrobenzyl bromide (Koshland's reagent). J Am Chem Soc (1968) 0.99
Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine. Chem Commun (Camb) (2004) 0.95
The reaction of Koshland's protein reagent with tryptophan. Tetrahedron Lett (1969) 0.93
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat Med (2011) 4.47
Enantioselective Heck arylations of acyclic alkenyl alcohols using a redox-relay strategy. Science (2012) 3.04
Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners. Chem Rev (2011) 2.88
Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Dis Model Mech (2008) 2.34
Three-dimensional correlation of steric and electronic free energy relationships guides asymmetric propargylation. Science (2011) 2.04
Palladium(II)-catalyzed enantioselective aerobic dialkoxylation of 2-propenyl phenols: a pronounced effect of copper additives on enantioselectivity. J Am Chem Soc (2007) 1.81
Recent advancements and challenges of palladium(II)-catalyzed oxidation reactions with molecular oxygen as the sole oxidant. Chem Commun (Camb) (2009) 1.72
MET and MYC cooperate in mammary tumorigenesis. Proc Natl Acad Sci U S A (2005) 1.70
Elucidating the significance of beta-hydride elimination and the dynamic role of acid/base chemistry in a palladium-catalyzed aerobic oxidation of alcohols. J Am Chem Soc (2004) 1.66
Recent progress in Wacker oxidations: moving toward molecular oxygen as the sole oxidant. Inorg Chem (2007) 1.58
Palladium-catalyzed oxidative intermolecular difunctionalization of terminal alkenes with organostannanes and molecular oxygen. Angew Chem Int Ed Engl (2009) 1.55
Palladium-catalyzed enantioselective addition of two distinct nucleophiles across alkenes capable of quinone methide formation. J Am Chem Soc (2009) 1.54
Multidimensional steric parameters in the analysis of asymmetric catalytic reactions. Nat Chem (2012) 1.46
Mechanistic approaches to palladium-catalyzed alkene difunctionalization reactions. Org Biomol Chem (2008) 1.45
Advancing the mechanistic understanding of an enantioselective palladium-catalyzed alkene difunctionalization reaction. J Am Chem Soc (2010) 1.42
Discovery of and mechanistic insight into a ligand-modulated palladium-catalyzed Wacker oxidation of styrenes using TBHP. J Am Chem Soc (2005) 1.42
A general and efficient catalyst system for a Wacker-type oxidation using TBHP as the terminal oxidant: application to classically challenging substrates. J Am Chem Soc (2009) 1.41
Mechanistic investigations of the palladium-catalyzed aerobic oxidative kinetic resolution of secondary alcohols using (-)-sparteine. J Am Chem Soc (2003) 1.40
Operationally simple and highly (E)-styrenyl-selective Heck reactions of electronically nonbiased olefins. J Am Chem Soc (2011) 1.40
Palladium(II)-catalyzed aerobic dialkoxylation of styrenes: a profound influence of an o-phenol. J Am Chem Soc (2006) 1.37
Discovery of a practical direct O2-coupled Wacker oxidation with Pd[(-)-sparteine]Cl2. Org Lett (2006) 1.36
Enantioselective redox-relay oxidative heck arylations of acyclic alkenyl alcohols using boronic acids. J Am Chem Soc (2013) 1.36
A highly selective and general palladium catalyst for the oxidative Heck reaction of electronically nonbiased olefins. J Am Chem Soc (2010) 1.31
A well-defined complex for palladium-catalyzed aerobic oxidation of alcohols: design, synthesis, and mechanistic considerations. Angew Chem Int Ed Engl (2003) 1.29
Pd(II)-catalyzed oxidative 1,1-diarylation of terminal olefins. Org Lett (2010) 1.27
Palladium-catalyzed reductive coupling of styrenes and organostannanes under aerobic conditions. J Am Chem Soc (2007) 1.22
Quantitatively correlating the effect of ligand-substituent size in asymmetric catalysis using linear free energy relationships. Angew Chem Int Ed Engl (2008) 1.22
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res (2003) 1.18
A palladium-catalyzed three-component cross-coupling of conjugated dienes or terminal alkenes with vinyl triflates and boronic acids. J Am Chem Soc (2011) 1.17
Transcription factor Oct1 is a somatic and cancer stem cell determinant. PLoS Genet (2012) 1.15
A pharmacogenomic method for individualized prediction of drug sensitivity. Mol Syst Biol (2011) 1.15
Palladium catalysts for aerobic oxidative kinetic resolution of secondary alcohols based on mechanistic insight. Org Lett (2003) 1.12
Systematically probing the effect of catalyst acidity in a hydrogen-bond-catalyzed enantioselective reaction. Angew Chem Int Ed Engl (2007) 1.12
Catalyst-controlled Wacker-type oxidation of protected allylic amines. Angew Chem Int Ed Engl (2010) 1.12
Palladium-catalyzed hydroalkylation of styrenes with organozinc reagents to form carbon-carbon sp3-sp3 bonds under oxidative conditions. J Am Chem Soc (2009) 1.12
Palladium-catalyzed hydroarylation of 1,3-dienes with boronic esters via reductive formation of pi-allyl palladium intermediates under oxidative conditions. J Am Chem Soc (2010) 1.10
Mechanism, reactivity, and selectivity in palladium-catalyzed redox-relay Heck arylations of alkenyl alcohols. J Am Chem Soc (2014) 1.10
On the mechanism of the palladium-catalyzed tert-butylhydroperoxide-mediated Wacker-type oxidation of alkenes using quinoline-2-oxazoline ligands. J Am Chem Soc (2011) 1.10
Experimental and computational study of a direct O2-coupled Wacker oxidation: water dependence in the absence of Cu salts. J Am Chem Soc (2010) 1.07
Synthesis of the reported structures for kealiinines B and C. Org Lett (2012) 1.07
An inducible system for the study of FGF signalling in early amphibian development. Dev Biol (2003) 1.05
Design and synthesis of modular oxazoline ligands for the enantioselective chromium-catalyzed addition of allyl bromide to ketones. J Am Chem Soc (2007) 1.05
Patient-derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicine. Curr Protoc Pharmacol (2013) 1.04
Palladium(II)-catalyzed aerobic hydroalkoxylation of styrenes containing a phenol. J Am Chem Soc (2006) 1.04
A convenient palladium-catalyzed aerobic oxidation of alcohols at room temperature. Chem Commun (Camb) (2002) 1.03
Origin of enantioselection in chiral alcohol oxidation catalyzed by Pd[(-)-sparteine]Cl2. J Am Chem Soc (2005) 1.03
Stereochemical diversity in chiral ligand design: discovery and optimization of catalysts for the enantioselective addition of allylic halides to aldehydes. Org Lett (2005) 1.03
Predicting and optimizing asymmetric catalyst performance using the principles of experimental design and steric parameters. Proc Natl Acad Sci U S A (2011) 1.02
Palladium-catalyzed 1,1-difunctionalization of ethylene. J Am Chem Soc (2012) 1.01
Applications of ortho-quinone methide intermediates in catalysis and asymmetric synthesis. J Org Chem (2011) 1.01
Mapping mammary gland architecture using multi-scale in situ analysis. Integr Biol (Camb) (2008) 1.00
Palladium-catalyzed 1,4-difunctionalization of butadiene to form skipped polyenes. J Am Chem Soc (2013) 0.98
Prediction of catalyst and substrate performance in the enantioselective propargylation of aliphatic ketones by a multidimensional model of steric effects. J Am Chem Soc (2013) 0.97
Aerobic alcohol oxidation coupled to palladium-catalyzed alkene hydroarylation with boronic esters. Angew Chem Int Ed Engl (2008) 0.97
Development of a general Pd(II)-catalyzed intermolecular hydroalkoxylation reaction of vinylphenols by using a sacrificial alcohol as the hydride source. Org Lett (2006) 0.96
Pd(0)-catalyzed 1,1-diarylation of ethylene and allylic carbonates. Org Lett (2013) 0.95
Palladium-catalyzed aerobic oxidative kinetic resolution of alcohols with an achiral exogenous base. J Org Chem (2003) 0.94
Using physical organic parameters to correlate asymmetric catalyst performance. J Org Chem (2013) 0.94
Palladium-catalyzed allylic cross-coupling reactions of primary and secondary homoallylic electrophiles. J Am Chem Soc (2012) 0.94
Coupling Pd-Catalyzed Alcohol Oxidation to Olefin Functionalization: Hydrohalogenation/Hydroalkoxylation of Styrenes. Organometallics (2007) 0.94
Mechanistic questions about the reaction of molecular oxygen with palladium in oxidase catalysis. Angew Chem Int Ed Engl (2006) 0.94
Linear free-energy relationship analysis of a catalytic desymmetrization reaction of a diarylmethane-bis(phenol). Org Lett (2010) 0.94
Investigating the nature of palladium chain-walking in the enantioselective redox-relay Heck reaction of alkenyl alcohols. J Org Chem (2014) 0.93
Dual role of (-)-sparteine in the palladium-catalyzed aerobic oxidative kinetic resolution of secondary alcohols. J Am Chem Soc (2002) 0.91
Development and comparison of the substrate scope of Pd-catalysts for the aerobic oxidation of alcohols. J Org Chem (2005) 0.89
Scope of enantioselective palladium(II)-catalyzed aerobic alcohol oxidations with (-)-sparteine. J Org Chem (2003) 0.89
A new approach to carbon-carbon bond formation: Development of aerobic Pd-catalyzed reductive coupling reactions of organometallic reagents and styrenes. Tetrahedron (2009) 0.89
Analyzing site selectivity in Rh2(esp)2-catalyzed intermolecular C-H amination reactions. J Am Chem Soc (2014) 0.88
Palladium-catalyzed hydrofunctionalization of vinyl phenol derivatives with heteroaromatics. Org Lett (2011) 0.88
Asymmetric palladium-catalyzed hydroarylation of styrenes and dienes. Tetrahedron (2011) 0.88
Using mechanistic and computational studies to explain ligand effects in the palladium-catalyzed aerobic oxidation of alcohols. J Am Chem Soc (2005) 0.87
Evaluation of catalyst acidity and substrate electronic effects in a hydrogen bond-catalyzed enantioselective reaction. J Org Chem (2010) 0.87
Diastereoselective synthesis of piperazines by manganese-mediated reductive cyclization. Org Lett (2003) 0.86
Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes. Genes Cancer (2012) 0.86
A palladium-catalyzed three-component-coupling strategy for the differential vicinal diarylation of terminal 1,3-dienes. Org Lett (2014) 0.85
Limiting-dilution transplantation assays in mammary stem cell studies. Methods Mol Biol (2010) 0.85
Unusual reactivity of molecular oxygen with pi-allylnickel(N-heterocyclic carbene) chloride complexes. J Am Chem Soc (2003) 0.85
Overview of human primary tumorgraft models: comparisons with traditional oncology preclinical models and the clinical relevance and utility of primary tumorgrafts in basic and translational oncology research. Curr Protoc Pharmacol (2012) 0.85
Design of hydrogen bond catalysts based on a modular oxazoline template: application to an enantioselective hetero Diels-Alder reaction. Org Lett (2005) 0.85
Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells. Breast Cancer Res (2013) 0.85
Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis. J Biol Chem (2012) 0.84
Oxygen-induced ligand dehydrogenation of a planar bis-mu-chloronickel(I) dimer featuring an NHC ligand. Inorg Chem (2005) 0.83
Anti-Markovnikov hydroalkylation of allylic amine derivatives via a palladium-catalyzed reductive cross-coupling reaction. J Am Chem Soc (2011) 0.83
Catalyst-controlled Wacker-type oxidation of homoallylic alcohols in the absence of protecting groups. J Org Chem (2011) 0.83
Modular synthesis of amine-functionalized oxazolines. Org Lett (2002) 0.82
Wacker-type oxidation of internal alkenes using Pd(Quinox) and TBHP. J Org Chem (2013) 0.82
Use of stem cell markers in dissociated mammary populations. Methods Mol Biol (2010) 0.81
Hybrid enzymatic and organic electrocatalytic cascade for the complete oxidation of glycerol. J Am Chem Soc (2014) 0.80
In situ analysis of cell populations: long-term label-retaining cells. Methods Mol Biol (2010) 0.80
Palladium(II)-catalyzed enantio- and diastereoselective synthesis of pyrrolidine derivatives. Org Lett (2012) 0.80
Distinctive meta-directing group effect for iridium-catalyzed 1,1-diarylalkene enantioselective hydrogenation. Org Lett (2013) 0.79
Pd(II)-catalyzed conversion of styrene derivatives to acetals: impact of (-)-sparteine on regioselectivity. Org Lett (2006) 0.79
The palladium-catalyzed anti-Markovnikov hydroalkylation of allylic alcohol derivatives. Org Lett (2012) 0.79