PubRank

Hyunah Choo

Author PubWeight™ 25.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antiviral activities and cellular toxicities of modified 2',3'-dideoxy-2',3'-didehydrocytidine analogues. Antimicrob Agents Chemother 2002 1.79
2 5- And 6-exocyclic products, cis-2,3,5-trisubstituted tetrahydrofurans, and cis-2,3,6-trisubstituted tetrahydropyrans via Prins-type cyclization. J Org Chem 2008 1.06
3 L-nucleosides: antiviral activity and molecular mechanism. Curr Top Med Chem 2002 0.99
4 Novel GSK-3beta inhibitors from sequential virtual screening. Bioorg Med Chem 2007 0.92
5 5-Exocyclic products, 2,3,5-trisubstituted tetrahydrofurans via Prins-type cyclization. Org Lett 2006 0.92
6 Novel quinazolinone derivatives as 5-HT7 receptor ligands. Bioorg Med Chem 2007 0.86
7 KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models. Pharmacol Biochem Behav 2010 0.86
8 IKKbeta inhibitors identification part II: ligand and structure-based virtual screening. Bioorg Med Chem 2010 0.85
9 Synthesis, structure-activity relationships, and mechanism of drug resistance of D- and L-beta-3'-fluoro-2',3'-unsaturated-4'-thionucleosides as anti-HIV agents. J Med Chem 2004 0.83
10 In vitro solubility, stability and permeability of novel quercetin-amino acid conjugates. Bioorg Med Chem 2008 0.80
11 Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides. J Med Chem 2002 0.80
12 IKKβ inhibitor identification: a multi-filter driven novel scaffold. BMC Bioinformatics 2010 0.80
13 IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening. Bioorg Med Chem 2009 0.80
14 New serotonin 5-HT(6) ligands from common feature pharmacophore hypotheses. J Chem Inf Model 2007 0.79
15 4-Aminoethylpiperazinyl aryl ketones with 5-HT₁A/5-HT₇ selectivity. Bioorg Med Chem 2011 0.79
16 Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors. Bioorg Med Chem Lett 2011 0.79
17 Identification of novel serotonin 2C receptor ligands by sequential virtual screening. Bioorg Med Chem 2009 0.79
18 Enhanced stability and intracellular accumulation of quercetin by protection of the chemically or metabolically susceptible hydroxyl groups with a pivaloxymethyl (POM) promoiety. J Med Chem 2010 0.79
19 Water-soluble and cleavable quercetin-amino acid conjugates as safe modulators for P-glycoprotein-based multidrug resistance. J Med Chem 2014 0.78
20 3D QSAR pharmacophore model based on diverse IKKβ inhibitors. J Mol Model 2010 0.78
21 Synthesis of beta-enantiomers of N4-hydroxy-3'-deoxypyrimidine nucleosides and their evaluation against bovine viral diarrhoea virus and hepatitis C virus in cell culture. Antivir Chem Chemother 2004 0.78
22 Classification of dopamine, serotonin, and dual antagonists by decision trees. Bioorg Med Chem 2006 0.78
23 Quercetin-POC conjugates: Differential stability and bioactivity profiles between breast cancer (MCF-7) and colorectal carcinoma (HCT116) cell lines. Bioorg Med Chem 2013 0.78
24 Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity. Org Biomol Chem 2015 0.77
25 Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson's disease. Bioorg Med Chem 2013 0.77
26 Quinazolindione derivatives as potent 5-HT3A receptor antagonists. Bioorg Med Chem 2009 0.77
27 Novel T-type calcium channel blockers: dioxoquinazoline carboxamide derivatives. Bioorg Med Chem 2006 0.77
28 Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers. Bioorg Med Chem Lett 2010 0.77
29 Synthesis and potent anti-HIV activity of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thiocytidine. Org Lett 2002 0.77
30 2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV). Eur J Med Chem 2011 0.77
31 3D pharmacophore based virtual screening of T-type calcium channel blockers. Bioorg Med Chem 2006 0.77
32 Effects of fluorine substitution of cytosine analogues on the binding affinity to HIV-1 reverse transcriptase. Bioorg Med Chem Lett 2004 0.76
33 Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers. Bioorg Med Chem Lett 2006 0.75
34 5-HT₃ antagonists under development. Expert Opin Investig Drugs 2010 0.75
35 Comparative QSAR studies on peptide deformylase inhibitors. J Mol Model 2007 0.75
36 Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers. Org Biomol Chem 2014 0.75
37 Selective inhibition of the hypoxia-inducible factor prolyl hydroxylase PHD3 by Zn(II). Chem Commun (Camb) 2015 0.75
38 Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment. Bioorg Med Chem Lett 2013 0.75
39 Separation of quercetin's biological activity from its oxidative property through bioisosteric replacement of the catecholic hydroxyl groups with fluorine atoms. J Agric Food Chem 2012 0.75
40 Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents. Bioorg Med Chem Lett 2010 0.75
41 Synthesis and biological evaluation of aryloxazole derivatives as antimitotic and vascular-disrupting agents for cancer therapy. J Med Chem 2013 0.75
42 Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists. ChemMedChem 2013 0.75
43 Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV). Antivir Chem Chemother 2006 0.75
44 Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT(7) ligands and role of the aromatic substituents in binding to the target receptor. Bioorg Med Chem 2013 0.75
45 2'-Fluoro-4'-thio-2',3'-unsaturated nucleosides: anti-HIV activity, resistance profile, and molecular modeling studies. Nucleosides Nucleotides Nucleic Acids 2003 0.75
46 Synthesis and antibacterial activities of new piperidine substituted (5R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3]triazolyl)methyl] oxazolidinones. Bioorg Med Chem Lett 2013 0.75
47 Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta[c]pyrrol-2-yl moieties. Chem Pharm Bull (Tokyo) 2014 0.75
48 Intermolecular double Prins-type cyclization: a facile and efficient synthesis of 1,6-dioxecanes. Angew Chem Int Ed Engl 2009 0.75