The neurobiology of the switch process in bipolar disorder: a review.

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Published in J Clin Psychiatry on May 04, 2010

Authors

Giacomo Salvadore1, Jorge A Quiroz, Rodrigo Machado-Vieira, Ioline D Henter, Husseini K Manji, Carlos A Zarate

Author Affiliations

1: Experimental Therapeutics, Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, Maryland, USA.

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Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci U S A (2004) 1.54

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Acute adverse reactions to prednisone in relation to dosage. Clin Pharmacol Ther (1972) 1.16

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Biphasic effect of D-2 agonist quinpirole on locomotion and movements. Eur J Pharmacol (1989) 1.14

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A double-blind trial of bupropion versus desipramine for bipolar depression. J Clin Psychiatry (1994) 1.01

The behavioral effects of REM sleep deprivation in rats. Psychophysiology (1970) 1.01

Modulation of brain gene expression during sleep and wakefulness: a review of recent findings. Neuropsychopharmacology (2001) 1.00

Psychosis in a child inhaling budesonide. Lancet (1983) 1.00

The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs. Arch Gen Psychiatry (1972) 1.00

Tranylcypromine versus imipramine in anergic bipolar depression. Am J Psychiatry (1991) 0.99

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Beclomethasone mania. Br J Psychiatry (1989) 0.94

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The role of the cingulate gyrus in depression: from functional anatomy to neurochemistry. Biol Psychiatry (1996) 0.94

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Predictors of switching from mania to depression in a large observational study across Europe (EMBLEM). J Affect Disord (2009) 0.93

A function for REM sleep: regulation of noradrenergic receptor sensitivity. Brain Res (1988) 0.92

Regular induction of hypomania by L-dopa in "bipolar" manic-depressive patients. Nature (1971) 0.90

Mood-stabilisers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar I depressed patients. J Affect Disord (2001) 0.90

Falret's discovery: the origin of the concept of bipolar affective illness. Translated by M. J. Sedler and Eric C. Dessain. Am J Psychiatry (1983) 0.90

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Biological and behavioral effects of one night's sleep deprivation in depressed patients and normals. J Psychiatr Res (1979) 0.87

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