PubRank

Debra C DuBois

Author PubWeight™ 38.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays. J Pharmacol Exp Ther 2003 1.71
2 The PEPR GeneChip data warehouse, and implementation of a dynamic time series query tool (SGQT) with graphical interface. Nucleic Acids Res 2004 1.40
3 Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats. J Pharmacokinet Pharmacodyn 2002 1.40
4 Pharmacodynamics and pharmacogenomics of methylprednisolone during 7-day infusions in rats. J Pharmacol Exp Ther 2002 1.36
5 Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats. J Endocrinol 2008 1.18
6 Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver. Funct Integr Genomics 2003 1.16
7 Corticosteroid-regulated genes in rat kidney: mining time series array data. Am J Physiol Endocrinol Metab 2005 1.14
8 Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle. Pharm Res 2006 1.10
9 Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens. Physiol Genomics 2007 1.10
10 Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action. Adv Drug Deliv Rev 2010 1.10
11 In vivo multi-tissue corticosteroid microarray time series available online at Public Expression Profile Resource (PEPR). Pharmacogenomics 2003 1.06
12 Circadian variations in rat liver gene expression: relationships to drug actions. J Pharmacol Exp Ther 2008 1.05
13 The genomic response of skeletal muscle to methylprednisolone using microarrays: tailoring data mining to the structure of the pharmacogenomic time series. Pharmacogenomics 2004 1.05
14 A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens. Endocrinology 2007 1.03
15 Receptor/gene-mediated pharmacodynamic effects of methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver. J Pharmacol Exp Ther 2004 1.02
16 Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats. Pharm Res 2007 0.98
17 Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis. J Pharmacokinet Pharmacodyn 2002 0.94
18 Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids. J Pharmacokinet Pharmacodyn 2007 0.93
19 Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats. J Pharmacol Exp Ther 2008 0.93
20 Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats. J Pharmacokinet Pharmacodyn 2010 0.90
21 Pharmacokinetic-pharmacodynamic disease progression model for effect of etanercept in Lewis rats with collagen-induced arthritis. Pharm Res 2011 0.90
22 Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling. J Pharmacokinet Pharmacodyn 2007 0.89
23 Importance of replication in analyzing time-series gene expression data: corticosteroid dynamics and circadian patterns in rat liver. BMC Bioinformatics 2010 0.87
24 Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats. Biopharm Drug Dispos 2007 0.85
25 Pharmacokinetic/pharmacodynamic modeling of corticosterone suppression and lymphocytopenia by methylprednisolone in rats. J Pharm Sci 2008 0.85
26 Circadian signatures in rat liver: from gene expression to pathways. BMC Bioinformatics 2010 0.83
27 Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats. Biopharm Drug Dispos 2012 0.81
28 Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by methylprednisolone in 60 rats. Anal Chem 2014 0.81
29 Pharmacokinetics, pharmacodynamics and toxicities of methotrexate in healthy and collagen-induced arthritic rats. Biopharm Drug Dispos 2013 0.81
30 Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach. J Pharmacokinet Pharmacodyn 2013 0.80
31 Application of scaling factors in simultaneous modeling of microarray data from diverse chips. Pharm Res 2007 0.80
32 Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats. Gene Regul Syst Bio 2008 0.79
33 Mechanistic modeling of the effects of glucocorticoids and circadian rhythms on adipokine expression. J Pharmacol Exp Ther 2011 0.79
34 Dynamic modeling of methylprednisolone effects on body weight and glucose regulation in rats. J Pharmacokinet Pharmacodyn 2011 0.78
35 Expression profiling and pharmacogenomics of muscle and muscle disease. Curr Opin Pharmacol 2003 0.76
36 Pharmacodynamic/pharmacogenomic modeling of insulin resistance genes in rat muscle after methylprednisolone treatment: exploring regulatory signaling cascades. Gene Regul Syst Bio 2008 0.76
37 Pharmacokinetic/pharmacodynamic modeling of methylprednisolone effects on iNOS mRNA expression and nitric oxide during LPS-induced inflammation in rats. Pharm Res 2012 0.76
38 Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics. OMICS 2015 0.76
39 Mechanistic population modeling of diabetes disease progression in Goto-Kakizaki rat muscle. Biopharm Drug Dispos 2010 0.75
40 A new symbolic representation for the identification of informative genes in replicated microarray experiments. OMICS 2010 0.75
41 Quantitation of expressed message for inducible nitric oxide synthase. Methods Enzymol 2002 0.75