PubRank

Suzie J Scales

Author PubWeight™ 47.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A paracrine requirement for hedgehog signalling in cancer. Nature 2008 8.16
2 Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell 2011 3.95
3 Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis. Proc Natl Acad Sci U S A 2009 3.13
4 CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell 2006 2.89
5 The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol 2009 2.63
6 Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance. Cancer Res 2010 2.45
7 Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates. Nat Biotechnol 2012 2.43
8 The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell 2013 2.42
9 TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev 2010 1.95
10 Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation. Mol Cell Biol 2010 1.81
11 Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates. Proc Natl Acad Sci U S A 2005 1.62
12 Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Res 2009 1.41
13 Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B. Dev Cell 2011 1.29
14 The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling. Nat Struct Mol Biol 2009 1.15
15 Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J Biol Chem 2010 1.13
16 Functional characterization of putative cilia genes by high-content analysis. Mol Biol Cell 2011 1.12
17 Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma. Blood 2007 1.11
18 High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate. Br J Haematol 2007 1.03
19 Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes. FEBS Lett 2011 1.00
20 Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake. Mol Cancer Ther 2008 0.98
21 DNA internalized via caveolae requires microtubule-dependent, Rab7-independent transport to the late endocytic pathway for delivery to the nucleus. J Biol Chem 2007 0.98
22 Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation. J Biol Chem 2011 0.93
23 FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther 2012 0.86
24 Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels. J Cell Biol 2013 0.84
25 DropArray™, a wall-less 96-well plate for uptake and immunofluorescence microscopy, confirms CD22 recycles. Traffic 2014 0.80