Published in Hepatology on June 01, 2010
PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice. Br J Cancer (2012) 1.10
PPARs in Liver Diseases and Cancer: Epigenetic Regulation by MicroRNAs. PPAR Res (2012) 1.03
Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer. PPAR Res (2012) 0.97
Peroxisome proliferator-activated receptors and cancer: challenges and opportunities. Br J Pharmacol (2011) 0.95
Pigment epithelium-derived factor (PEDF) promotes tumor cell death by inducing macrophage membrane tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J Biol Chem (2011) 0.93
PPARγ Promotes Growth and Invasion of Thyroid Cancer Cells. PPAR Res (2011) 0.90
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma. Cell Death Dis (2013) 0.89
Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway. Oncotarget (2014) 0.87
Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer. Cancers (Basel) (2011) 0.86
Inhibition of oxidative stress-elicited AKT activation facilitates PPARγ agonist-mediated inhibition of stem cell character and tumor growth of liver cancer cells. PLoS One (2013) 0.84
Thyroid-specific transcription factors and their roles in thyroid cancer. J Thyroid Res (2011) 0.83
PPARs Signaling and Cancer in the Gastrointestinal System. PPAR Res (2012) 0.83
MiR-27a promotes hepatocellular carcinoma cell proliferation through suppression of its target gene peroxisome proliferator-activated receptor γ. Chin Med J (Engl) (2015) 0.82
PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma. PPAR Res (2012) 0.79
MicroRNAs-Dependent Regulation of PPARs in Metabolic Diseases and Cancers. PPAR Res (2017) 0.78
PPARs and Mitochondrial Metabolism: From NAFLD to HCC. PPAR Res (2016) 0.77
Identifying prognostic features by bottom-up approach and correlating to drug repositioning. PLoS One (2015) 0.77
Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma. J Hepatocell Carcinoma (2014) 0.76
Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma. Oncogene (2016) 0.76
Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription. J Clin Invest (2017) 0.75
Hepatitis D and hepatocellular carcinoma. World J Hepatol (2015) 0.75
Dietary restriction protects against diethylnitrosamine-induced hepatocellular tumorigenesis by restoring the disturbed gene expression profile. Sci Rep (2017) 0.75
Peroxisome Proliferator-Activated Receptor γ Expression Is Inversely Associated with Macroscopic Vascular Invasion in Human Hepatocellular Carcinoma. Int J Mol Sci (2016) 0.75
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. J Exp Med (2017) 0.75
A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med (2003) 21.55
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med (2004) 10.31
Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med (2005) 6.39
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis. N Engl J Med (2002) 6.15
Viral loads and duration of viral shedding in adult patients hospitalized with influenza. J Infect Dis (2009) 5.23
Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A (2005) 5.05
Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol (2008) 4.44
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Gastrointest Endosc (2006) 4.31
Omeprazole before endoscopy in patients with gastrointestinal bleeding. N Engl J Med (2007) 4.29
Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study. Gastroenterology (2013) 3.55
Hepatitis B virus reactivation in lymphoma patients with prior resolved hepatitis B undergoing anticancer therapy with or without rituximab. J Clin Oncol (2008) 3.44
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients. Clin Cancer Res (2009) 3.41
CISH and susceptibility to infectious diseases. N Engl J Med (2010) 3.31
Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection. N Engl J Med (2015) 3.16
Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol (2002) 3.13
A phenylalanine in DGAT is a key determinant of oil content and composition in maize. Nat Genet (2008) 2.89
MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology (2008) 2.88
miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell (2010) 2.87
Management of antithrombotic agents for endoscopic procedures. Gastrointest Endosc (2009) 2.84
TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. J Am Soc Nephrol (2011) 2.78
Sedation and anesthesia in GI endoscopy. Gastrointest Endosc (2008) 2.73
An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival. J Exp Med (2008) 2.68
An outbreak of severe acute respiratory syndrome among hospital workers in a community hospital in Hong Kong. Ann Intern Med (2003) 2.67
1-(2-Chloro-phen-yl)-2-(isopropyl-amino)ethanol. Acta Crystallogr Sect E Struct Rep Online (2009) 2.65
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res (2006) 2.63
ASGE guideline: colorectal cancer screening and surveillance. Gastrointest Endosc (2006) 2.63
What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific? J Gastroenterol Hepatol (2007) 2.54
Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial. Lancet (2002) 2.52
Comparison of EUS and ERCP in the investigation with suspected biliary obstruction caused by choledocholithiasis: a randomized study. Gastrointest Endosc (2007) 2.50
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis (2009) 2.45
Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science (2012) 2.44
Cholecystectomy or gallbladder in situ after endoscopic sphincterotomy and bile duct stone removal in Chinese patients. Gastroenterology (2006) 2.37
Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection. Gastroenterology (2003) 2.36
MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma. Carcinogenesis (2012) 2.32
Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out of hospital: prospective observational study. BMJ (2003) 2.30
Dieulafoy's lesion. Gastrointest Endosc (2003) 2.29
Use of infliximab within 3 months of ileocolonic resection is associated with adverse postoperative outcomes in Crohn's patients. J Gastrointest Surg (2008) 2.29
Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial. Gastroenterology (2004) 2.28
Genetics of inflammatory bowel disease in Asia: systematic review and meta-analysis. Inflamm Bowel Dis (2011) 2.24
Fecal viral load and norovirus-associated gastroenteritis. Emerg Infect Dis (2006) 2.20
Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis. BMJ (2003) 2.20
Therapeutic Armamentarium for Stricturing Crohn's Disease: Medical Versus Endoscopic Versus Surgical Approaches. Inflamm Bowel Dis (2015) 2.13
Seasonal influenza activity in Hong Kong and its association with meteorological variations. J Med Virol (2009) 2.12
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling. Science (2010) 2.09
Antibiotic prophylaxis for GI endoscopy. Gastrointest Endosc (2008) 2.08
Infection control during GI endoscopy. Gastrointest Endosc (2008) 2.07
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing. Proc Natl Acad Sci U S A (2013) 2.05
T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model. Radiology (2011) 2.05
Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am J Gastroenterol (2006) 2.05
Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc (2010) 2.04
Twenty-year-old stapled pouches for ulcerative colitis without evidence of rectal cancer: implications for surveillance strategy? Dis Colon Rectum (2014) 2.01
A tumor progression model for hepatocellular carcinoma: bioinformatic analysis of genomic data. Gastroenterology (2006) 1.99
TTF-1 expression in breast carcinoma: an unusual but real phenomenon. Histopathology (2013) 1.96
Prokinetics in acute upper GI bleeding: a meta-analysis. Gastrointest Endosc (2010) 1.95
Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg (2013) 1.91
Capsule endoscopy or angiography in patients with acute overt obscure gastrointestinal bleeding: a prospective randomized study with long-term follow-up. Am J Gastroenterol (2012) 1.88
Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis. Gastroenterology (2012) 1.87
Endoscopic therapy versus medical therapy for bleeding peptic ulcer with adherent clot: a meta-analysis. Gastroenterology (2005) 1.85
Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. J Gastroenterol Hepatol (2012) 1.83
Epidemiological and virological characteristics of 2 subgroups of hepatitis B virus genotype C. J Infect Dis (2005) 1.81
Human metapneumovirus detection in patients with severe acute respiratory syndrome. Emerg Infect Dis (2003) 1.81
Postischemic brain injury is exacerbated in mice lacking the kinin B2 receptor. Hypertension (2006) 1.80
Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in noncancerous stomach. Clin Cancer Res (2006) 1.79
Risk of colonoscopic polypectomy bleeding with anticoagulants and antiplatelet agents: analysis of 1657 cases. Gastrointest Endosc (2004) 1.78
Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res (2002) 1.74
Preoperative colorectal neoplasia increases risk for pouch neoplasia in patients with restorative proctocolectomy. Gastroenterology (2010) 1.72
Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma. Clin Cancer Res (2002) 1.71
Diagnosis of gastric cancer by serum proteomic fingerprinting. Gastroenterology (2006) 1.71
Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. Am J Gastroenterol (2010) 1.70
Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches. Semin Cancer Biol (2012) 1.69
Esophageal dilation. Gastrointest Endosc (2006) 1.68
Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. Clin Cancer Res (2011) 1.68
WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer. Clin Cancer Res (2008) 1.67
Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome. Clin Chem (2003) 1.67
Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway. Cardiovasc Res (2008) 1.67
Zinc-finger protein 545 is a novel tumour suppressor that acts by inhibiting ribosomal RNA transcription in gastric cancer. Gut (2012) 1.67
Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer. Gastroenterology (2008) 1.66
FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. PLoS One (2013) 1.65
N-[2-(2-Chloro-phen-yl)-2-hydroxy-ethyl]propan-2-aminium hemioxalate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.62
MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling. Clin Cancer Res (2010) 1.61
EUS in the management of uninvestigated dyspepsia. Gastrointest Endosc (2002) 1.60
Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22. Neoplasia (2009) 1.59
Risk and location of cancer in patients with preoperative colitis-associated dysplasia undergoing proctocolectomy. Ann Surg (2014) 1.58
Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis. Gastroenterology (2004) 1.58
EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis. Cancer Res (2011) 1.58