Published in Neuropsychopharmacology on June 02, 2010
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) (2013) 2.01
The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders. Br J Pharmacol (2011) 1.39
Role of dorsal medial prefrontal cortex dopamine D1-family receptors in relapse to high-fat food seeking induced by the anxiogenic drug yohimbine. Neuropsychopharmacology (2010) 1.21
Contributions of serotonin in addiction vulnerability. Neuropharmacology (2011) 1.12
The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. Neuropsychopharmacology (2011) 1.11
Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues. Neuropharmacology (2011) 1.07
Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. Pharmacol Rev (2015) 1.06
Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction. Neuropharmacology (2013) 1.05
Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2010) 0.99
Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Res (2014) 0.97
Compulsivity in anorexia nervosa: a transdiagnostic concept. Front Psychol (2014) 0.95
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect. Addict Biol (2011) 0.93
Orexin/hypocretin role in reward: implications for opioid and other addictions. Br J Pharmacol (2014) 0.92
Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedside. Pharmacol Ther (2012) 0.92
A multivariate assessment of individual differences in sensation seeking and impulsivity as predictors of amphetamine self-administration and prefrontal dopamine function in rats. Exp Clin Psychopharmacol (2011) 0.91
The role of the dorsal raphé nucleus in reward-seeking behavior. Front Integr Neurosci (2013) 0.91
Convergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models. Br J Pharmacol (2014) 0.90
Serotonin (2C) receptor regulation of cocaine-induced conditioned place preference and locomotor sensitization. Behav Brain Res (2012) 0.90
Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. Front Neurosci (2013) 0.88
Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex. Neuroscience (2015) 0.84
Protracted withdrawal from cocaine self-administration flips the switch on 5-HT(1B) receptor modulation of cocaine abuse-related behaviors. Biol Psychiatry (2012) 0.84
Extinction under a behavioral microscope: isolating the sources of decline in operant response rate. Behav Processes (2012) 0.84
Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. Neuropsychopharmacology (2013) 0.83
Variation within the serotonin (5-HT) 5-HT₂C receptor system aligns with vulnerability to cocaine cue reactivity. Transl Psychiatry (2014) 0.81
Investigating Methamphetamine Craving Using the Extinction-Reinstatement Model in the Rat. J Addict Res Ther (2011) 0.80
Serotonin2C receptors and drug addiction: focus on cocaine. Exp Brain Res (2013) 0.78
Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects. J Psychopharmacol (2013) 0.77
The serotonin 5-HT2C receptor in medial prefrontal cortex exerts rheostatic control over the motivational salience of cocaine-associated cues: new observations from preclinical animal research. Neuropsychopharmacology (2010) 0.76
Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system. Neuroscience (2016) 0.76
Behavioral, pharmacological and neuroanatomical analysis of serotonin 2C receptor agonism on maternal behavior in rats. Psychoneuroendocrinology (2016) 0.76
Pharmacological evidence for an abstinence-induced switch in 5-HT1B receptor modulation of cocaine self-administration and cocaine-seeking behavior. ACS Chem Neurosci (2014) 0.75
5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen. Synapse (2012) 0.75
Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37
Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry (2002) 10.34
Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli. Psychopharmacology (Berl) (1999) 7.06
Limbic activation during cue-induced cocaine craving. Am J Psychiatry (1999) 6.66
A review of central 5-HT receptors and their function. Neuropharmacology (1999) 6.13
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J Neurosci (2001) 5.18
Anticraving medications for relapse prevention: a possible new class of psychoactive medications. Am J Psychiatry (2005) 4.80
Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J Comp Neurol (2005) 4.65
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. Psychopharmacology (Berl) (2006) 4.23
Reinstatement of cocaine-reinforced responding in the rat. Psychopharmacology (Berl) (1981) 3.90
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology (2005) 3.28
Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats. J Neurosci (2008) 3.20
Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. J Neurosci (2000) 2.86
Selective inactivation of the dorsomedial prefrontal cortex and the basolateral amygdala attenuates conditioned-cued reinstatement of extinguished cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2002) 2.79
Neurobiology of craving, conditioned reward and relapse. Curr Opin Pharmacol (2005) 2.47
On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience (1992) 2.23
Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Brain Res Mol Brain Res (1994) 2.21
A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2002) 2.08
Role of ventral medial prefrontal cortex in incubation of cocaine craving. Neuropharmacology (2008) 1.99
Limbic-striatal memory systems and drug addiction. Neurobiol Learn Mem (2002) 1.82
SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology (1997) 1.76
Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br J Pharmacol (1999) 1.67
Local-circuit neurones in the medial prefrontal cortex (areas 25, 32 and 24b) in the rat: morphology and quantitative distribution. J Comp Neurol (1997) 1.64
Prospects for serotonin 5-HT2R pharmacotherapy in psychostimulant abuse. Prog Brain Res (2008) 1.62
Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations. J Clin Psychopharmacol (1993) 1.60
The prefrontal cortex regulates the basal release of dopamine in the limbic striatum: an effect mediated by ventral tegmental area. J Neurochem (1996) 1.55
Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding. Neuropsychopharmacology (2002) 1.49
Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS. Neuropharmacology (2000) 1.43
Role of conditioned reinforcers in the initiation, maintenance and extinction of drug-seeking behavior. Pavlov J Biol Sci (1977) 1.38
Topography of serotonin neurons in the dorsal raphe nucleus that send axon collaterals to the rat prefrontal cortex and nucleus accumbens. Brain Res (1993) 1.34
Pharmacological and environmental determinants of relapse to cocaine-seeking behavior. Pharmacol Biochem Behav (1999) 1.34
The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues. Neuropsychopharmacology (2007) 1.32
Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization. Eur J Neurosci (1999) 1.27
Addiction as a pathology in prefrontal cortical regulation of corticostriatal habit circuitry. Neurotox Res (2008) 1.26
Stimulation of serotonin2C receptors influences cocaine-seeking behavior in response to drug-associated stimuli in rats. Psychopharmacology (Berl) (2007) 1.23
Electrical stimulation of the prefrontal cortex increases cholecystokinin, glutamate, and dopamine release in the nucleus accumbens: an in vivo microdialysis study in freely moving rats. J Neurosci (1998) 1.21
Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior. J Pharmacol Exp Ther (2000) 1.21
Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats. Behav Pharmacol (2007) 1.20
Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behav Neurosci (2009) 1.20
Neuronal calcium-binding proteins and schizophrenia. Schizophr Res (2002) 1.19
Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism. J Neurosci (2002) 1.17
Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addiction. Neuroscience (2007) 1.16
Elevated expression of 5-HT1B receptors in nucleus accumbens efferents sensitizes animals to cocaine. J Neurosci (2002) 1.14
Influence of individual differences and chronic fluoxetine treatment on cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2001) 1.14
Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference. Brain Res (2003) 1.12
Dual dopamine/serotonin releasers: potential treatment agents for stimulant addiction. Exp Clin Psychopharmacol (2008) 1.06
Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology (2004) 1.05
Fluoxetine alters the effects of intravenous cocaine in humans. J Clin Psychopharmacol (1994) 1.04
Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice. J Neurosci (2002) 1.04
Effects of fluoxetine and d-fenfluramine on cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2003) 1.02
Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex. J Pharmacol Exp Ther (2003) 1.01
Selective visualization of rat brain 5-HT2A receptors by autoradiography with [3H]MDL 100,907. Naunyn Schmiedebergs Arch Pharmacol (1997) 1.01
Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. J Neurosci (2009) 1.00
Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration. Neuropsychopharmacology (2004) 0.97
Effect of atypical antipsychotic drugs on 5-HT2 receptors in the rat orbito-frontal cortex: an in vivo electrophysiological study. Psychopharmacology (Berl) (1999) 0.96
Evidence for a selective prefrontal cortical GABA(B) receptor-mediated inhibition of glutamate release in the ventral tegmental area: a dual probe microdialysis study in the awake rat. Neuroscience (2005) 0.96
Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5-HT2C receptor stimulation and not by D1 receptor blockade. Neuropsychopharmacology (2005) 0.94
Regional distribution and cellular localization of 5-HT2C receptor mRNA in monkey brain: comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA. Synapse (2001) 0.94
Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans. Biol Psychiatry (1998) 0.92
Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse (1992) 0.90
Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [3H]phosphatidylinositols. Naunyn Schmiedebergs Arch Pharmacol (2002) 0.89
Treating crack cocaine dependence: the critical role of relapse prevention. J Psychoactive Drugs (1992) 0.89
Serotonin depletion attenuates cocaine-seeking behavior in rats. Psychopharmacology (Berl) (1999) 0.88
Stimulation of 5-HT(1B) receptors enhances cocaine reinforcement yet reduces cocaine-seeking behavior. Addict Biol (2009) 0.87
mRNAs for clozapine-sensitive receptors co-localize in rat prefrontal cortex neurons. Neurosci Lett (1998) 0.87
Serotonin depletion attenuates cocaine seeking but enhances sucrose seeking and the effects of cocaine priming on reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2001) 0.87
Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats. Pharmacol Rep (2005) 0.87
Effect of schedule of reinforcement on cue-elicited reinstatement of cocaine-seeking behavior. Behav Pharmacol (2008) 0.87
Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry (1995) 0.86
Increase of extracellular glutamate and expression of Fos-like immunoreactivity in the ventral tegmental area in response to electrical stimulation of the prefrontal cortex. J Neurochem (1998) 0.86
Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl) (1995) 0.83
Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. Eur J Pharmacol (1989) 0.83
Differences in the laminar origin of projections from the medial prefrontal cortex to the nucleus accumbens shell and core regions in the rat. Brain Res (2001) 0.81
Repeated cocaine modifies the neuroendocrine responses to the 5-HT1C/5-HT2 receptor agonist DOI. Eur J Pharmacol (1992) 0.80
Parameters of intracranial self-administration of cocaine into the medial prefrontal cortex. NIDA Res Monogr (1984) 0.80
Repeated administration of low doses of cocaine enhances the sensitivity of 5-HT2 receptor function. Pharmacol Biochem Behav (1992) 0.79
Chronic cocaine exposure potentiates prolactin and head shake responses to 5-HT2 receptor stimulation in rats. Neuropharmacology (1996) 0.78
Fluoxetine attenuates adrenocortical but not subjective responses to cocaine cues. Am J Drug Alcohol Abuse (2004) 0.78
Blunted oral body temperature response to MK-212 in cocaine addicts. Drug Alcohol Depend (1994) 0.77
Repeated cocaine exposure inhibits the adrenocorticotropic hormone response to the serotonin releaser d-fenfluramine and the 5-HT1A agonist, 8-OH-DPAT. Neuropharmacology (1994) 0.77
Repeated cocaine administration reduces 5-HT1A-mediated prolactin secretion in rats. Neurosci Lett (1995) 0.76
Withdrawal from continuous or intermittent cocaine: behavioral responsivity to 5-HT1 receptor agonists. Pharmacol Biochem Behav (1993) 0.76
Effect of 5,7-dihydroxytryptamine lesion on mianserin-induced conditioned place aversion and on 5-hydroxytryptamine1C receptors in the rat brain. Neuroscience (1993) 0.76
Effect of sleep deprivation on the performance of simulated laparoscopic surgical skill. Am J Surg (2003) 1.86
Synergistic interaction between nicotine and social rewards in adolescent male rats. Psychopharmacology (Berl) (2009) 1.59
Social reward-conditioned place preference: a model revealing an interaction between cocaine and social context rewards in rats. Drug Alcohol Depend (2008) 1.57
Effects of excitotoxic lesions of the basolateral amygdala on cocaine-seeking behavior and cocaine conditioned place preference in rats. Brain Res (2002) 1.35
Anti-craving effects of environmental enrichment. Int J Neuropsychopharmacol (2009) 1.25
Ratio and time requirements on operant schedules: effort-related effects of nucleus accumbens dopamine depletions. Eur J Neurosci (2005) 1.22
Dorsal hippocampus inhibition disrupts acquisition and expression, but not consolidation, of cocaine conditioned place preference. Behav Neurosci (2006) 1.21
Increases in dopamine D3 receptor binding in rats receiving a cocaine challenge at various time points after cocaine self-administration: implications for cocaine-seeking behavior. Neuropsychopharmacology (2004) 1.21
c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues. Synapse (2009) 1.18
Accumbens dopamine and the regulation of effort in food-seeking behavior: modulation of work output by different ratio or force requirements. Behav Brain Res (2004) 1.17
Blockade or stimulation of D1 dopamine receptors attenuates cue reinstatement of extinguished cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2001) 1.16
Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference. Brain Res (2003) 1.12
Dorsal, but not ventral, hippocampal lesions disrupt cocaine place conditioning. Neuroreport (2003) 1.11
Effects of SCH-23390 infused into the amygdala or adjacent cortex and basal ganglia on cocaine seeking and self-administration in rats. Neuropsychopharmacology (2006) 1.06
Upregulation of Arc mRNA expression in the prefrontal cortex following cue-induced reinstatement of extinguished cocaine-seeking behavior. Synapse (2008) 1.05
Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology (2004) 1.05
Limited physical contact through a mesh barrier is sufficient for social reward-conditioned place preference in adolescent male rats. Physiol Behav (2011) 1.03
Effects of fluoxetine and d-fenfluramine on cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2003) 1.02
Blockade of 5-HT2A receptors in the medial prefrontal cortex attenuates reinstatement of cue-elicited cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2010) 0.99
The interactive effects of environmental enrichment and extinction interventions in attenuating cue-elicited cocaine-seeking behavior in rats. Pharmacol Biochem Behav (2010) 0.96
Substance use disorders and PTSD: an exploratory study of treatment preferences among military veterans. Addict Behav (2013) 0.94
The isolation of motivational, motoric, and schedule effects on operant performance: a modeling approach. J Exp Anal Behav (2011) 0.94
Environmental enrichment counters cocaine abstinence-induced stress and brain reactivity to cocaine cues but fails to prevent the incubation effect. Addict Biol (2011) 0.93
Region-specific involvement of AMPA/Kainate receptors in Fos protein expression induced by cocaine-conditioned cues. Eur Neuropsychopharmacol (2008) 0.92
Routine upper gastrointestinal Gastrografin swallow after laparoscopic Roux-en-Y gastric bypass. Obes Surg (2003) 0.90
A new criterion for acquisition of nicotine self-administration in rats. Drug Alcohol Depend (2012) 0.88
Effect of schedule of reinforcement on cue-elicited reinstatement of cocaine-seeking behavior. Behav Pharmacol (2008) 0.87
Stimulation of 5-HT(1B) receptors enhances cocaine reinforcement yet reduces cocaine-seeking behavior. Addict Biol (2009) 0.87
Effects of 7-OH-DPAT on cocaine-seeking behavior and on re-establishment of cocaine self-administration. Pharmacol Biochem Behav (2002) 0.86
A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model. Pharmacol Biochem Behav (2008) 0.86
Stimulation of dopamine D2/D3 but not D1 receptors in the central amygdala decreases cocaine-seeking behavior. Behav Brain Res (2010) 0.85
Stimulation of 5-HT1B receptors decreases cocaine- and sucrose-seeking behavior. Pharmacol Biochem Behav (2005) 0.85
Protracted withdrawal from cocaine self-administration flips the switch on 5-HT(1B) receptor modulation of cocaine abuse-related behaviors. Biol Psychiatry (2012) 0.84
Extinction under a behavioral microscope: isolating the sources of decline in operant response rate. Behav Processes (2012) 0.84
Cocaine-induced Fos expression is detectable in the frontal cortex and striatum of rats under isoflurane but not alpha-chloralose anesthesia: implications for FMRI. J Neurosci Methods (2009) 0.83
Modeling the effects of fluoxetine on food-reinforced behavior. Behav Pharmacol (2008) 0.83
D1-receptor drugs and cocaine-seeking behavior: investigation of receptor mediation and behavioral disruption in rats. Psychopharmacology (Berl) (2003) 0.82
The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors. Psychopharmacology (Berl) (2007) 0.81
Mood symptoms contribute to working memory decrement in active-duty soldiers being treated for posttraumatic stress disorder. Brain Behav (2012) 0.79
Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. J Pharmacol Exp Ther (2013) 0.78
Novel cues reinstate cocaine-seeking behavior and induce Fos protein expression as effectively as conditioned cues. Neuropsychopharmacology (2012) 0.78
Pharmacological evidence for an abstinence-induced switch in 5-HT1B receptor modulation of cocaine self-administration and cocaine-seeking behavior. ACS Chem Neurosci (2014) 0.75
5-HT(2A) receptor blockade and 5-HT(2C) receptor activation interact to reduce cocaine hyperlocomotion and Fos protein expression in the caudate-putamen. Synapse (2012) 0.75
Fos expression in response to dopamine D3-preferring phenylpiperazine drugs given with and without cocaine. Synapse (2013) 0.75
Cancer risk in endoscopically unresectable colon polyps. Am J Surg (2006) 0.75