Published in J Exp Clin Cancer Res on June 03, 2010
EMMPRIN promotes angiogenesis, proliferation, invasion and resistance to sunitinib in renal cell carcinoma, and its level predicts patient outcome. PLoS One (2013) 0.91
Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation. Leukemia (2012) 0.91
Role of emmprin in endometrial cancer. BMC Cancer (2012) 0.90
CD147 expression in human gastric cancer is associated with tumor recurrence and prognosis. PLoS One (2014) 0.88
The role of EMMPRIN expression in ovarian epithelial carcinomas. Cell Cycle (2013) 0.87
New insights into germ cell migration and survival/apoptosis in spermatogenesis: Lessons from CD147. Spermatogenesis (2012) 0.85
Downregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer. Oncol Lett (2014) 0.76
CD147 promotes the proliferation, invasiveness, migration and angiogenesis of human lung carcinoma cells. Oncol Lett (2016) 0.75
Role of miR-647 in human gastric cancer suppression. Oncol Rep (2017) 0.75
CD147 knockdown improves the antitumor efficacy of trastuzumab in HER2-positive breast cancer cells. Oncotarget (2016) 0.75
Combination of VP3 and CD147-knockdown enhance apoptosis and tumor growth delay index in colorectal tumor allograft. BMC Cancer (2016) 0.75
CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways. Oncotarget (2016) 0.75
A system for stable expression of short interfering RNAs in mammalian cells. Science (2002) 35.21
Cancer burden in the year 2000. The global picture. Eur J Cancer (2001) 10.47
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Axis of evil: molecular mechanisms of cancer metastasis. Oncogene (2003) 2.81
Combined transcriptome and genome analysis of single micrometastatic cells. Nat Biotechnol (2002) 2.48
Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res (2005) 2.42
Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. Int J Cancer (2002) 2.39
EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie (2005) 2.10
CD147 immunoglobulin superfamily receptor function and role in pathology. Exp Mol Pathol (2007) 1.77
Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN. Mol Cancer Res (2004) 1.73
Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression. Pathol Int (2006) 1.71
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Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production. Cancer Res (2004) 1.61
Regulation of multidrug resistance in cancer cells by hyaluronan. J Biol Chem (2003) 1.61
Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147. Cancer (2006) 1.59
A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res (2006) 1.46
Dealing with the family: CD147 interactions with cyclophilins. Immunology (2006) 1.46
Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway. Mol Cancer Res (2006) 1.45
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res (1993) 1.41
Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res (2003) 1.39
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis. Br J Cancer (2006) 1.36
RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion. Cancer Lett (2008) 1.10
Involvement of CD147 in regulation of multidrug resistance to P-gp substrate drugs and in vitro invasion in breast cancer cells. Cancer Sci (2007) 1.05
Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells. Cancer Lett (2006) 0.92
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells. Cancer Sci (2007) 0.91
Silencing CD147 inhibits tumor progression and increases chemosensitivity in murine lymphoid neoplasm P388D1 cells. Ann Hematol (2009) 0.81
Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism (2009) 1.73
Analysis of long non-coding RNA expression profiles in gastric cancer. World J Gastroenterol (2013) 1.50
CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women. J Clin Pharmacol (2010) 1.44
The prognostic value of preoperative NLR, d-NLR, PLR and LMR for predicting clinical outcome in surgical colorectal cancer patients. Med Oncol (2014) 1.16
Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals. Eur J Clin Pharmacol (2012) 0.99
CagA+ H pylori infection is associated with polarization of T helper cell immune responses in gastric carcinogenesis. World J Gastroenterol (2007) 0.97
Association of NAT2, GSTM1, GSTT1, CYP2A6, and CYP2A13 gene polymorphisms with susceptibility and clinicopathologic characteristics of bladder cancer in Central China. Cancer Detect Prev (2009) 0.95
CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients. Eur J Clin Pharmacol (2009) 0.95
Genetic variation in the promoter of DNMT3B is associated with the risk of colorectal cancer. Int J Colorectal Dis (2011) 0.93
Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis. Int J Colorectal Dis (2011) 0.90
Pharmacokinetics of three proton pump inhibitors in Chinese subjects in relation to the CYP2C19 genotype. Eur J Clin Pharmacol (2006) 0.90
Polymorphisms in interleukin-1B (IL-1B) and interleukin 1 receptor antagonist (IL-1RN) genes associate with gastric cancer risk in the Chinese population. Dig Dis Sci (2011) 0.88
Qualified kidney biomarkers and their potential significance in drug safety evaluation and prediction. Pharmacol Ther (2012) 0.87
Serum CEA level change and its significance before and after Gefitinib therapy on patients with advanced non-small cell lung cancer. Asian Pac J Cancer Prev (2013) 0.86
Attenuated expression of the tight junction proteins is involved in clopidogrel-induced gastric injury through p38 MAPK activation. Toxicology (2012) 0.84
Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system. Mol Cancer (2012) 0.84
MRI shows clodronate-liposomes attenuating liver injury in rats with severe acute pancreatitis. Hepatobiliary Pancreat Dis Int (2010) 0.83
CES1A -816C as a genetic marker to predict greater platelet clopidogrel response in patients with percutaneous coronary intervention. J Cardiovasc Pharmacol (2014) 0.82
Association between polymorphisms in RAPGEF1, TP53, NRF1 and type 2 diabetes in Chinese Han population. Diabetes Res Clin Pract (2010) 0.81
[Polymorphisms of DNA methyltransferases and the risk of prostate cancer]. Zhonghua Nan Ke Xue (2014) 0.80
CYP3A4 * 1G Genetic Polymorphism Influences Metabolism of Fentanyl in Human Liver Microsomes in Chinese Patients. Pharmacology (2015) 0.80
Roles of E-cadherin (CDH1) genetic variations in cancer risk: a meta-analysis. Asian Pac J Cancer Prev (2014) 0.80
[Changes of regulatory T cells and T helper cells in peripheral blood and their roles in the severity evaluation in children with asthma]. Zhongguo Dang Dai Er Ke Za Zhi (2011) 0.79
Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. J Food Sci (2012) 0.79
[Effect of Rapamycin and Cyclosporin A on the expression of TLR5 and Foxp3 in allorejection]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2009) 0.79
Urinary modified nucleosides as novel biomarkers for diagnosis and prognostic monitoring of urothelial bladder cancer. Tumori (2015) 0.79
Targeted tumor gene therapy based on loss of IGF2 imprinting. Cancer Biol Ther (2010) 0.79
Reduced expression of SK3 and IK1 channel proteins in the cavernous tissue of diabetic rats. Asian J Androl (2010) 0.78
Influence of CYP3A5*3 polymorphism and interaction between CYP3A5*3 and CYP3A4*1G polymorphisms on post-operative fentanyl analgesia in Chinese patients undergoing gynaecological surgery. Eur J Anaesthesiol (2011) 0.78
Preparation and characterization of anti-GP73 monoclonal antibodies and development of double-antibody sandwich ELISA. Asian Pac J Cancer Prev (2015) 0.78
Celecoxib inhibits insulin-like growth factor 1 induced growth and invasion in non-small cell lung cancer. Oncol Lett (2013) 0.78
Blockage of hERG current and the disruption of trafficking as induced by roxithromycin. Can J Physiol Pharmacol (2013) 0.77
The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel. Basic Clin Pharmacol Toxicol (2010) 0.77
Increased endoplasmic reticulum stress response is involved in clopidogrel-induced apoptosis of gastric epithelial cells. PLoS One (2013) 0.77
Effect of CYP3A4*1G, CYP3A5*3, POR*28, and ABCB1 C3435T on the pharmacokinetics of nifedipine in healthy Chinese volunteers. Int J Clin Pharmacol Ther (2015) 0.77
Independent anti-inflammatory effect of insulin in newly diagnosed type 2 diabetes. Diabetes Metab Res Rev (2009) 0.77
Interaction between M-CSF and IL-10 on productions of IL-12 and IL-18 and expressions of CD14, CD23, and CD64 by human monocytes. Acta Pharmacol Sin (2004) 0.77
Effects of UGT1A1*6, UGT1A1*28, and ABCB1-3435C>T polymorphisms on irinotecaninduced toxicity in Chinese cancer patients. Int J Clin Pharmacol Ther (2016) 0.76
Efffect of the ABCC3 -211C/T polymorphism on clopidogrel responsiveness in patients with percutaneous coronary intervention. Clin Exp Pharmacol Physiol (2013) 0.76
Inhibitory effects of α-pinene on hepatoma carcinoma cell proliferation. Asian Pac J Cancer Prev (2014) 0.75
Effect of endothelin-1 on cyclooxygenase-2 expression in human hormone refractory prostate cancer cells. Oncol Lett (2010) 0.75
Function of regulatory T-cells improved by dexamethasone in Graves' disease. Eur J Endocrinol (2012) 0.75
Degradation of Reactive Brilliant Red X-3B by zero-valent iron/activated carbon system in the presence of microwave irradiation. Water Sci Technol (2011) 0.75
[Effect of Helicobacter pylori lipopolysaccharide on expression of Gli and Ptch-1 proteins in sonic hedgehog signaling pathway of gastric mucosa GES-1 cells]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2013) 0.75
[Effect of recombinant adenovirus Ad-DT-A in targeted therapy for malignant cancer cell lines with loss of IGF2 imprinting]. Zhonghua Zhong Liu Za Zhi (2011) 0.75
The molecular mechanism underlying the induction of hepatic MRP3 expression and function by omeprazole. Biopharm Drug Dispos (2015) 0.75
Synthesis and antimicrobial activities of oximes derived from O-benzylhydroxylamine as FabH inhibitors. ChemMedChem (2012) 0.75
Influence of piperacillin on pharmacokinetics of etimicin in healthy volunteers. Acta Pharmacol Sin (2002) 0.75
Using estimative reaction free energy to predict splice sites and their flanking competitors. Gene (2008) 0.75
[Study on extraction of coumarins in Cnidium monieri by supercritical CO2 and separation of compositions analysis]. Zhongguo Zhong Yao Za Zhi (2005) 0.75
Interspecific competition between Microcystis aeruginosa and Anabaena flos-aquae from Taihu Lake, China. Z Naturforsch C (2014) 0.75
CYP2C19 681G > A polymorphism and pharmacokinetics of clopidogrel in Chinese healthy volunteers. Pharmazie (2012) 0.75
Design, synthesis and biological evaluation of N-phenylsulfonylnicotinamide derivatives as novel antitumor inhibitors. Bioorg Med Chem (2012) 0.75
[Epidermal growth factor up-regulates the mRNA expression of endothelin-1 and its receptors in prostate cancer PC-3 cell lines]. Zhonghua Nan Ke Xue (2008) 0.75
Pharmacokinetics of simvastatin lactone and its active metabolite simvastatin hydroxy acid in healthy Chinese male and female volunteers. Int J Clin Pharmacol Ther (2014) 0.75
[Discovery and genetic analysis of blue-eyed mutant in the white rex rabbits]. Yi Chuan (2013) 0.75
Paraoxonase-1 Q192R polymorphism is not associated with clopidogrel response in Chinese stroke patients. Pharmazie (2012) 0.75
[Influence of SNCG transfection on the effectiveness of anti-tumor drugs in PC-3 cell lines]. Zhonghua Nan Ke Xue (2008) 0.75
Prevention of relapse of Graves' disease by treatment with an intrathyroid injection of dexamethasone. J Clin Endocrinol Metab (2009) 0.75
MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model. Neuroreport (2017) 0.75
[Detection of sexual hormone in semen of patients with idiopathic azoospermia or oligospermia and its significance]. Zhonghua Nan Ke Xue (2003) 0.75
Enhanced Platelet Response to Clopidogrel in Abcc3-deficient Mice Due to Its Increased Bioactivation. J Cardiovasc Pharmacol (2016) 0.75
Lenalidomide in treating patients with castration-resistant prostate cancer. Asian Pac J Cancer Prev (2015) 0.75