Published in Nanomedicine (Lond) on June 01, 2010
A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands. ACS Nano (2010) 2.27
Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors. AIP Adv (2012) 1.35
Gold nanoparticles in biology and medicine: recent advances and prospects. Acta Naturae (2011) 1.12
Toxicity of engineered nanomaterials: a physicochemical perspective. J Biochem Mol Toxicol (2012) 0.98
Blood-nanoparticle interactions and in vivo biodistribution: impact of surface PEG and ligand properties. Mol Pharm (2012) 0.96
Effects of surface functional groups on the formation of nanoparticle-protein corona. Appl Phys Lett (2012) 0.96
Anti-HER2 antibody and ScFvEGFR-conjugated antifouling magnetic iron oxide nanoparticles for targeting and magnetic resonance imaging of breast cancer. Int J Nanomedicine (2013) 0.91
Improving delivery and efficacy of nanomedicines in solid tumors: role of tumor priming. Nanomedicine (Lond) (2011) 0.91
Paclitaxel-loaded iron platinum stealth immunomicelles are potent MRI imaging agents that prevent prostate cancer growth in a PSMA-dependent manner. Int J Nanomedicine (2012) 0.90
Nanomedical engineering: shaping future nanomedicines. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2014) 0.89
Selective targeting of antibody conjugated multifunctional nanoclusters (nanoroses) to epidermal growth factor receptors in cancer cells. Langmuir (2011) 0.89
Delivery of siRNA silencing Runx2 using a multifunctional polymer-lipid nanoparticle inhibits osteogenesis in a cell culture model of heterotopic ossification. Integr Biol (Camb) (2012) 0.88
Doxorubicin-Loaded PEG-PCL-PEG Micelle Using Xenograft Model of Nude Mice: Effect of Multiple Administration of Micelle on the Suppression of Human Breast Cancer. Cancers (Basel) (2010) 0.87
Image-guided local delivery strategies enhance therapeutic nanoparticle uptake in solid tumors. ACS Nano (2013) 0.87
'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities. Nanotechnology (2013) 0.85
177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model. Nucl Med Biol (2013) 0.85
Nanodrug delivery systems: a promising technology for detection, diagnosis, and treatment of cancer. AAPS PharmSciTech (2014) 0.85
Evidences For Charge Transfer-Induced Conformational Changes In Carbon Nanostructure-Protein Corona. J Phys Chem C Nanomater Interfaces (2012) 0.85
Nanotechnology and the treatment of HIV infection. Viruses (2012) 0.84
Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles. Int J Nanomedicine (2012) 0.84
Magnetic Nanoparticle Facilitated Drug Delivery for Cancer Therapy with Targeted and Image-Guided Approaches. Adv Funct Mater (2016) 0.84
Targeted delivery system of nanobiomaterials in anticancer therapy: from cells to clinics. Biomed Res Int (2014) 0.83
Multimeric Near IR-MR Contrast Agent for Multimodal In Vivo Imaging. J Am Chem Soc (2015) 0.83
USNCTAM perspectives on mechanics in medicine. J R Soc Interface (2014) 0.83
Selective targeting of melanoma by PEG-masked protein-based multifunctional nanoparticles. Int J Nanomedicine (2012) 0.82
Nano-sized and micro-sized polystyrene particles affect phagocyte function. Cell Biol Toxicol (2013) 0.82
Cell and nanoparticle transport in tumour microvasculature: the role of size, shape and surface functionality of nanoparticles. Interface Focus (2016) 0.81
Mixed nanomicelles as potential carriers for systemic delivery of Z-GP-Dox, an FAPα-based doxorubicin prodrug: formulation and pharmacokinetic evaluation. Int J Nanomedicine (2015) 0.79
Real-time monitoring of magnetic drug targeting using fibered confocal fluorescence microscopy. J Control Release (2016) 0.78
Accelerated blood clearance phenomenon upon cross-administration of PEGylated nanocarriers in beagle dogs. Int J Nanomedicine (2015) 0.78
PEG-b-AGE Polymer Coated Magnetic Nanoparticle Probes with Facile Functionalization and Anti-fouling Properties for Reducing Non-specific Uptake and Improving Biomarker Targeting. J Mater Chem B Mater Biol Med (2015) 0.78
Design strategy of surface decoration for efficient delivery of nanoparticles by computer simulation. Sci Rep (2016) 0.77
The influence of linker length on the properties of cathepsin S cleavable (177)Lu-labeled HPMA copolymers for pancreatic cancer imaging. Biomaterials (2014) 0.77
Anthracycline Drugs on Modified Surface of Quercetin-Loaded Polymer Nanoparticles: A Dual Drug Delivery Model for Cancer Treatment. PLoS One (2016) 0.77
AntihypoxamiR functionalized gramicidin lipid nanoparticles rescue against ischemic memory improving cutaneous wound healing. Nanomedicine (2016) 0.76
Anti-HER2/neu peptide-conjugated iron oxide nanoparticles for targeted delivery of paclitaxel to breast cancer cells. Nanoscale (2015) 0.76
Comparison of Confocal and Super-Resolution Reflectance Imaging of Metal Oxide Nanoparticles. PLoS One (2016) 0.75
Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide-siRNA Nanocomplexes. Bioconjug Chem (2016) 0.75
Nanotechnology for cancer treatment. Nanotechnol Rev (2015) 0.75
A review on current nanomaterials and their drug conjugate for targeted breast cancer treatment. Int J Nanomedicine (2017) 0.75
Improving sensitivity and specificity of capturing and detecting targeted cancer cells with anti-biofouling polymer coated magnetic iron oxide nanoparticles. Colloids Surf B Biointerfaces (2016) 0.75
Drug-targeting methodologies with applications: A review. World J Clin Cases (2014) 0.75
MR imaging enables measurement of therapeutic nanoparticle uptake in rat N1-S1 liver tumors after nanoablation. J Vasc Interv Radiol (2014) 0.75
Using Nanoparticles in Medicine for Liver Cancer Imaging. Oman Med J (2017) 0.75
The effects of non-invasive radiofrequency electric field hyperthermia on biotransport and biodistribution of fluorescent [60]fullerene derivative in a murine orthotopic model of breast adenocarcinoma. J Control Release (2017) 0.75
In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol (2004) 17.47
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res (1986) 15.83
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release (2000) 14.89
Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer (2005) 13.49
Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater (2009) 11.95
Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev (2001) 10.02
Drug penetration in solid tumours. Nat Rev Cancer (2006) 9.80
The use of nanocrystals in biological detection. Nat Biotechnol (2004) 8.34
Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int J Pharm (2005) 7.53
Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc Natl Acad Sci U S A (2007) 7.50
In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol (2006) 6.93
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci U S A (2008) 5.76
Immunological properties of engineered nanomaterials. Nat Nanotechnol (2007) 5.59
Nanoparticle and targeted systems for cancer therapy. Adv Drug Deliv Rev (2004) 5.31
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging. Proc Natl Acad Sci U S A (2007) 5.17
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res (2006) 4.43
Nanomedicine: current status and future prospects. FASEB J (2005) 4.28
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst (2006) 4.27
Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell (2009) 4.02
In vivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol (2005) 3.92
Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog Lipid Res (2003) 3.89
Nanotechnology applications in cancer. Annu Rev Biomed Eng (2007) 3.88
Transport of molecules, particles, and cells in solid tumors. Annu Rev Biomed Eng (1999) 3.64
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54
Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angew Chem Int Ed Engl (2007) 3.41
'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf B Biointerfaces (2000) 3.33
Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv Drug Deliv Rev (2008) 3.18
The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. Clin Immunol (2006) 3.08
Nanomedicine--challenge and perspectives. Angew Chem Int Ed Engl (2009) 2.74
Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv Drug Deliv Rev (2006) 2.69
Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. Cancer Res (1990) 2.61
Seven challenges for nanomedicine. Nat Nanotechnol (2008) 2.59
Folate receptor-mediated drug targeting: from therapeutics to diagnostics. J Pharm Sci (2005) 2.46
Nanotechnology safety concerns revisited. Toxicol Sci (2007) 2.41
Nanotechnology and cancer. Annu Rev Med (2008) 2.25
The role of complement in inflammation and phagocytosis. Immunol Today (1991) 2.04
Theranostic nanomedicine for cancer. Nanomedicine (Lond) (2008) 1.96
Nanoparticles evading the reticuloendothelial system: role of the supported bilayer. Biochim Biophys Acta (2009) 1.94
Does a targeting ligand influence nanoparticle tumor localization or uptake? Trends Biotechnol (2008) 1.94
Parameters influencing the stealthiness of colloidal drug delivery systems. Biomaterials (2006) 1.94
Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging (1998) 1.77
Influence of surface charge density on protein adsorption on polymeric nanoparticles: analysis by two-dimensional electrophoresis. Eur J Pharm Biopharm (2002) 1.55
Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats. Eur J Pharm Biopharm (1998) 1.54
Analysis of plasma protein adsorption on polymeric nanoparticles with different surface characteristics. J Biomed Mater Res (1998) 1.51
Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. J Control Release (2001) 1.51
Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenografts. Hum Gene Ther (1999) 1.45
Tumor targeting with RGD peptide ligands-design of new molecular conjugates for imaging and therapy of cancers. Anticancer Agents Med Chem (2007) 1.34
Minimizing the hydrodynamic size of quantum dots with multifunctional multidentate polymer ligands. J Am Chem Soc (2008) 1.26
Cellular dynamics of EGF receptor-targeted synthetic viruses. Mol Ther (2007) 1.25
Next-generation quantum dots. Nat Biotechnol (2009) 1.25
Selective gene delivery for cancer therapy using cationic liposomes: in vivo proof of applicability. J Control Release (2006) 1.02
In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol (2004) 17.47
In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags. Nat Biotechnol (2007) 7.33
Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res (2008) 5.67
Luminescent quantum dots for multiplexed biological detection and imaging. Curr Opin Biotechnol (2002) 4.93
In vivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol (2005) 3.92
Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv Drug Deliv Rev (2008) 3.18
Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging. J Am Chem Soc (2008) 2.79
Bioimaging: second window for in vivo imaging. Nat Nanotechnol (2009) 2.48
Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry. Nat Protoc (2007) 2.45
Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol Cancer Ther (2006) 2.38
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res (2004) 2.31
A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands. ACS Nano (2010) 2.27
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy. Int J Nanomedicine (2008) 2.20
Self-assembled nanoparticle probes for recognition and detection of biomolecules. J Am Chem Soc (2002) 2.18
Alloyed semiconductor quantum dots: tuning the optical properties without changing the particle size. J Am Chem Soc (2003) 2.00
Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. J Am Chem Soc (2007) 1.98
Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings. J Am Chem Soc (2007) 1.95
Emerging use of nanoparticles in diagnosis and treatment of breast cancer. Lancet Oncol (2006) 1.94
Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging. Small (2009) 1.93
Quantum-dot nanocrystals for ultrasensitive biological labeling and multicolor optical encoding. J Biomed Opt (2002) 1.92
Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells. Nucleic Acids Res (2004) 1.89
A systematic examination of surface coatings on the optical and chemical properties of semiconductor quantum dots. Phys Chem Chem Phys (2006) 1.88
Receptor-targeted nanoparticles for in vivo imaging of breast cancer. Clin Cancer Res (2009) 1.86
Using solution-phase nanoparticles, surface-confined nanoparticle arrays and single nanoparticles as biological sensing platforms. J Fluoresc (2004) 1.73
Counting single native biomolecules and intact viruses with color-coded nanoparticles. Anal Chem (2006) 1.64
Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain. Nat Nanotechnol (2008) 1.63
Multicolor quantum dots for molecular diagnostics of cancer. Expert Rev Mol Diagn (2006) 1.63
Spectroscopic tags using dye-embedded nanoparticles and surface-enhanced Raman scattering. Anal Chem (2003) 1.61
Development of multifunctional nanoparticles for targeted drug delivery and noninvasive imaging of therapeutic effect. Curr Drug Discov Technol (2009) 1.60
Hand-held spectroscopic device for in vivo and intraoperative tumor detection: contrast enhancement, detection sensitivity, and tissue penetration. Anal Chem (2010) 1.47
Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles. Gastroenterology (2009) 1.47
Semiconductor nanocrystals: structure, properties, and band gap engineering. Acc Chem Res (2010) 1.46
Quantum dot nanocrystals for in vivo molecular and cellular imaging. Photochem Photobiol (2004) 1.36
Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles. Cancer Res (2011) 1.36
Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging. Nanomedicine (Lond) (2006) 1.32
Molecular mapping of tumor heterogeneity on clinical tissue specimens with multiplexed quantum dots. ACS Nano (2010) 1.31
Oxidative quenching and degradation of polymer-encapsulated quantum dots: new insights into the long-term fate and toxicity of nanocrystals in vivo. J Am Chem Soc (2008) 1.31
Nanotechnology applications in surgical oncology. Annu Rev Med (2010) 1.31
Intraoperative near-infrared imaging of surgical wounds after tumor resections can detect residual disease. Clin Cancer Res (2012) 1.30
HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors. ACS Nano (2009) 1.29
Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer. ACS Nano (2013) 1.28
Engineering luminescent quantum dots for in vivo molecular and cellular imaging. Ann Biomed Eng (2006) 1.26
Minimizing the hydrodynamic size of quantum dots with multifunctional multidentate polymer ligands. J Am Chem Soc (2008) 1.26
Mesoporous silica beads embedded with semiconductor quantum dots and iron oxide nanocrystals: dual-function microcarriers for optical encoding and magnetic separation. Anal Chem (2006) 1.25
Next-generation quantum dots. Nat Biotechnol (2009) 1.25
Nanotechnology for targeted cancer therapy. Expert Rev Anticancer Ther (2007) 1.21
Semiconductor quantum dots for bioimaging and biodiagnostic applications. Annu Rev Anal Chem (Palo Alto Calif) (2013) 1.18
Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes. Proc Natl Acad Sci U S A (2008) 1.17
Molecular profiling of single cells and tissue specimens with quantum dots. Trends Biotechnol (2003) 1.14
Quantum dot-encoded mesoporous beads with high brightness and uniformity: rapid readout using flow cytometry. Anal Chem (2004) 1.13
Chemical analysis and cellular imaging with quantum dots. Analyst (2004) 1.11
Surface-enhanced Raman nanoparticle beacons based on bioconjugated gold nanocrystals and long range plasmonic coupling. J Am Chem Soc (2008) 1.07
Physical chemistry of nanomedicine: understanding the complex behaviors of nanoparticles in vivo. Annu Rev Phys Chem (2015) 1.04
Minimizing nonspecific cellular binding of quantum dots with hydroxyl-derivatized surface coatings. Anal Chem (2008) 1.03
Etching colloidal gold nanocrystals with hyperbranched and multivalent polymers: a new route to fluorescent and water-soluble atomic clusters. J Am Chem Soc (2007) 1.03
Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange. J Am Chem Soc (2010) 1.01
Quantum dots for in vivo molecular and cellular imaging. Methods Mol Biol (2007) 1.00
Multiplexed detection and characterization of rare tumor cells in Hodgkin's lymphoma with multicolor quantum dots. Anal Chem (2010) 0.99
Targeted delivery of cisplatin to lung cancer using ScFvEGFR-heparin-cisplatin nanoparticles. ACS Nano (2011) 0.95
Stimuli-responsive SERS nanoparticles: conformational control of plasmonic coupling and surface Raman enhancement. J Am Chem Soc (2009) 0.94
A folate receptor-targeting nanoparticle minimizes drug resistance in a human cancer model. ACS Nano (2011) 0.94
Visualizing human prostate cancer cells in mouse skeleton using bioconjugated near-infrared fluorescent quantum dots. Urology (2009) 0.93
Re-examining the origins of spectral blinking in single-molecule and single-nanoparticle SERS. Faraday Discuss (2006) 0.91
Compact quantum dots for single-molecule imaging. J Vis Exp (2012) 0.90
Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotechnol (2009) 0.90
Quantitative 3D fluorescence technique for the analysis of en face preparations of arterial walls using quantum dot nanocrystals and two-photon excitation laser scanning microscopy. Am J Physiol Regul Integr Comp Physiol (2005) 0.90
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug. Head Neck (2009) 0.89
Proton-Resistant Quantum Dots: Stability in Gastrointestinal Fluids and Implications for Oral Delivery of Nanoparticle Agents. Nano Res (2009) 0.87
An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors. IEEE Trans Biomed Eng (2015) 0.86
Imaging dynamic cellular events with quantum dots The bright future. Biochem (Lond) (2010) 0.86
Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes. J Virol (2005) 0.85
Quantum dots: emerging applications in urologic oncology. Urol Oncol (2008) 0.84
Anchoring molecular chromophores to colloidal gold nanocrystals: surface-enhanced Raman evidence for strong electronic coupling and irreversible structural locking. J Am Chem Soc (2012) 0.84
Single-bead immunoassays using magnetic microparticles and spectral-shifting quantum dots. J Agric Food Chem (2007) 0.83
A new class of far-red and near-infrared biological labels based on alloyed semiconductor quantum dots. J Nanosci Nanotechnol (2004) 0.83
The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas. Ann Surg (2015) 0.83
Molecular profiling of single cancer cells and clinical tissue specimens with semiconductor quantum dots. Int J Nanomedicine (2006) 0.82
Molecular imaging to identify tumor recurrence following chemoradiation in a hostile surgical environment. Mol Imaging (2014) 0.82
Quantum dot-encoded beads. Methods Mol Biol (2005) 0.82
One-pot synthesis, encapsulation, and solubilization of size-tuned quantum dots with amphiphilic multidentate ligands. J Am Chem Soc (2008) 0.81
Multidentate-protected colloidal gold nanocrystals: pH control of cooperative precipitation and surface layer shedding. J Am Chem Soc (2011) 0.79
Nanocrystal synthesis in an amphibious bath: spontaneous generation of hydrophilic and hydrophobic surface coatings. Angew Chem Int Ed Engl (2008) 0.78
Compact and blinking-suppressed quantum dots for single-particle tracking in live cells. J Phys Chem B (2014) 0.77
New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I). Nanomedicine (2006) 0.77
Bio-nano-informatics: an integrated information management system for personalized oncology. Conf Proc IEEE Eng Med Biol Soc (2006) 0.77
Quality control of highly multiplexed proteomic immunostaining with quantum dots: correcting for crosstalk. Conf Proc IEEE Eng Med Biol Soc (2009) 0.75
Nanomolecular histopathology for renal tumor classification. Conf Proc IEEE Eng Med Biol Soc (2005) 0.75
A stilbene-based fluoroionophore for copper ion sensing in both reduced and oxidized environments. Talanta (2010) 0.75
An unusual role of folate in the self-assembly of heparin-folate conjugates into nanoparticles. Nanoscale (2015) 0.75
Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. Conf Proc IEEE Eng Med Biol Soc (2005) 0.75
Optically encoded nanoparticles for detecting single biomolecules and viruses: rapid analysis of two-color colocalization data by high-speed computing. Conf Proc IEEE Eng Med Biol Soc (2005) 0.75